β 1-adrenergic receptor antagonists signal via PDE4 translocation

EMBO Reports

Volumn 14, Issue 3, 2013, Pages 276-283

  Richter, Wito ^a   Mika, Delphine ^a   Blanchard, Elise ^a   Day, Peter ^b,c   Conti, Marco ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Roche Group   (United States)

Author keywords

adrenergic receptor; antagonist; cAMP; cyclic nucleotide phosphodiesterase; PDE

Indexed keywords

ADENYLATE CYCLASE; BETA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHODIESTERASE IV;

ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN HYDROLYSIS; RECEPTOR OCCUPANCY; SIGNAL TRANSDUCTION;

ADRENERGIC BETA-1 RECEPTOR ANTAGONISTS; CELL MEMBRANE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; HEK293 CELLS; HUMANS; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTORS, ADRENERGIC, BETA-1; SIGNAL TRANSDUCTION;

EID: 84874649848     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2013.4     Document Type: Article

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