Baicalein protects against retinal ischemia by antioxidation, antiapoptosis, downregulation of HIF-1α, VEGF, and MMP-9 and upregulation of HO-1

Journal of Ocular Pharmacology and Therapeutics

Volumn 29, Issue 6, 2013, Pages 539-549

  Chao, Hsiao Ming ^a,b   Chuang, Min Jay ^b   Liu, Jorn Hon ^a,b   Liu, Xiao Qian ^c   Ho, Li Kang ^b   Pan, Wynn H T ^b   Zhang, Xiu Mei ^c   Liu, Chi Ming ^a,b   Tsai, Shen Kou ^a   Kong, Chi Woon ^a   Lee, Shou Dong ^a   Chen, Mi Mi ^a   Chao, Fang Ping ^a  

^a CHENG HSIN GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ANTIOXIDANT; ASCORBIC ACID; BAICALEIN; CHOLINE ACETYLTRANSFERASE; DICHLOROFLUORESCEIN; FERROUS ASCORBATE; GELATINASE B; HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TROLOX C; VASCULOTROPIN; VIMENTIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY LABELING; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; B WAVE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ELECTROPHYSIOLOGY; ELECTRORETINOGRAM; ENZYME INDUCTION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; INTRAOCULAR HYPERTENSION; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; RAT; REAL TIME POLYMERASE CHAIN REACTION; RETINA AMACRINE CELL; RETINA GANGLION CELL; RETINA ISCHEMIA; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL LINE; DOWN-REGULATION; FLAVANONES; HEME OXYGENASE-1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTRAVITREAL INJECTIONS; ISCHEMIA; MATRIX METALLOPROTEINASE 9; RATS; RATS, WISTAR; RETINA; RETINAL DISEASES; RETINAL VESSELS; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84880199900     PISSN: 10807683     EISSN: 15577732     Source Type: Journal    
DOI: 10.1089/jop.2012.0179     Document Type: Article

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