Influence of plasticizers on the stability and release of a prodrug of Δ9-tetrahydrocannabinol incorporated in poly (ethylene oxide) matrices

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 70, Issue 2, 2008, Pages 605-614

  Thumma, Sridhar ^a   ElSohly, Mahmoud A ^a,b,c   Zhang, Shuang Qing ^a   Gul, Waseem ^b,c   Repka, Michael A ^a,b  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c ElSohly Laboratories   (United States)

Author keywords

Hot melt; Microenvironmental pH; Plasticizers; Poly (ethylene oxide); Prodrug; Release; Stability; THC

Indexed keywords

ALPHA TOCOPHEROL SUCCINATE; CITRIC ACID TRIETHYL ESTER; DRONABINOL; DRONABINOL HEMIGLUTARATE; MACROGOL; PLASTICIZER; PRODRUG; UNCLASSIFIED DRUG;

ARTICLE; DRUG DEGRADATION; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; MISCIBILITY; PH; THERMOSTABILITY;

CITRIC ACID; DRUG STABILITY; PLASTICIZERS; POLYETHYLENE GLYCOLS; PRODRUGS; SOLUBILITY; TETRAHYDROCANNABINOL; VISCOSITY;

EID: 52949087902     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.06.009     Document Type: Article

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