Enantioselective synthesis and physicochemical properties of libraries of 3-amino- and 3-amidofluoropiperidines

Chemistry - A European Journal

Volumn 20, Issue 13, 2014, Pages 3813-3824

  Orliac, Aurélie ^a   Routier, Julie ^b   Burgat Charvillon, Fabienne ^b   Sauer, Wolfgang H B ^b   Bombrun, Agnes ^a,b   Kulkarni, Santosh S ^c   Gomez Pardo, Domingo ^a   Cossy, Janine ^a  

^a PSL RESEARCH UNIVERSITY   (France)

^b MERCK SERONO S A   (Switzerland)

^c SYNGENE INTERNATIONAL LTD   (India)

Author keywords

basicity; enantioselectivity; fluorine; lipophilicity; stereoelectronic effects

Indexed keywords

ALKALINITY; ATOMS; ENANTIOSELECTIVITY; LIBRARIES;

AXIAL POSITIONS; COMMON SOFTWARE; DIPOLE DIPOLE INTERACTIONS; ENANTIOSELECTIVE SYNTHESIS; LIPOPHILICITY; PHYSICOCHEMICAL PROPERTY; RING ENLARGEMENT; STEREOELECTRONIC EFFECT;

FLUORINE;

EID: 84896388774     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201302423     Document Type: Article

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