Tanshinone IIA attenuates the inflammatory response and apoptosis after traumatic injury of the spinal cord in adult rats

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Yin, Xin ^a   Yin, Yue ^a   Cao, Fa Le ^b   Chen, Yu Fei ^a   Peng, Ye ^a   Hou, Wu Gang ^a   Sun, Shu Kai ^c   Luo, Zhuo Jing ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b The 222th Hospital of CPLA Jilin   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MYELOPEROXIDASE; PROTEIN BCL 2; TANSHINONE IIA; TUMOR NECROSIS FACTOR ALPHA; ABIETANE DERIVATIVE; AUTACOID; BIOLOGICAL MARKER; CYTOKINE; TANSHINONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASTROCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; EDEMA; ENZYME ACTIVITY; INFLAMMATION; INJURY SEVERITY; LAMINECTOMY; LOCOMOTION; MOTOR PERFORMANCE; NEUTROPHIL CHEMOTAXIS; NICK END LABELING; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; RAT; SCORING SYSTEM; SIGNAL TRANSDUCTION; SPINAL CORD INJURY; THORACIC SPINE; TISSUE INJURY; AGING; ANIMAL; CONVALESCENCE; DRUG EFFECT; ENZYMOLOGY; INJURY; MALE; METABOLISM; PATHOLOGY; SPINAL CORD; SPRAGUE DAWLEY RAT;

RATTUS; SALVIA MILTIORRHIZA;

AGING; ANIMALS; APOPTOSIS; ASTROCYTES; BIOLOGICAL MARKERS; CYTOKINES; DITERPENES, ABIETANE; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; MAP KINASE SIGNALING SYSTEM; NEUTROPHIL INFILTRATION; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SPINAL CORD; SPINAL CORD INJURIES; WOUNDS AND INJURIES;

EID: 84861740605     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038381     Document Type: Article

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