Neutrophil fate in experimental glomerular capillary injury in the rat: Emigration exceeds in situ clearance by apoptosis

American Journal of Pathology

Volumn 150, Issue 1, 1997, Pages 223-234

  Hughes, Jeremy ^a   Johnson, Richard J ^b   Mooney, Andrew ^a   Hugo, Christian ^b   Gordon, Kathy ^a   Savill, John ^b  

^a NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONCANAVALIN A;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL INFILTRATION; CELL MIGRATION; CONTROLLED STUDY; DIAGNOSIS; ENDOTHELIUM CELL; GLOMERULONEPHRITIS; LEUKOCYTE ACTIVATION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; CAPILLARIES; CELL MOVEMENT; CONCANAVALIN A; GLOMERULONEPHRITIS; INDIUM RADIOISOTOPES; INFUSIONS, INTRAVENOUS; KIDNEY GLOMERULUS; LYMPH NODES; MACROPHAGES; MALE; NEUTROPHILS; PHAGOCYTOSIS; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 0031021556     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Linas SL, Whittenburg D, Repine JE: Role of neutrophil derived oxidants and elastase in LPS-mediated renal injury. Kidney Int 1991, 39:618-623
2. Cochrane CG: Immunologie tissue injury mediated by neutrophil leukocytes. Adv Immunol 1968, 9:97-165
3. Henson PM: Pathologic mechanisms in neutrophil-mediated injury. Am J Pathol 1972, 68:593-604
4. Naish PF, Thompson NM, Simpson U, Peters DK: The role of polymorphonuclear leucocytes in the autologous phase of nephrotoxtc nephritis. Clin Exp Immunol 1975, 22:102-111
5. 2-halide system in immune complex nephritis. Kidney Int 1987, 32:342-349
6. Henson PM, Johnston RB: Tissue injury in inflammation: oxidants, proteinases, and cationic proteins. J Clin Invest 1987, 79:669-674
7. Johnson RJ, Couser WG, Alpers CE, Vissers M, Schulze M, Klebanoff SJ: The human neutrophil serine proteinase and cathepsin can mediate glomerular injury in vivo. J Exp Med 1988, 168:1169-1174
8. Johnson RJ, Alpers CE, Pruchro C, Schulze M, Baker PJ, Pritzl P, Couser WG: Mechanism and kinetics for platelet and neutrophil localisation in immune complex nephritis, Kidney Int 1989, 36:780-789
9. Savill J, Wyllie AH, Henson JE, Walport MJ, Henson PM, Haslett C: Macrophage phagocytosis of aging neutrophils in inflammation: programmed cell death in the neutrophil leads to its recognition by macrophages. J Clin Invest 1989, 83:865-875
10. Grigg JM, Savill JS, Sarraf C, Haslett C, Silverman M: Neonatal apoptosis and clearance from neonatal lungs. Lancet 1991, 338:720-722
11. Cox G, Crossley J, Xing Z: Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo. Am J Respir Cell Mol Biol 1995, 12:232-237
12. Sanui H, Yoshida S, Nomoto K, Ohhara R, Adachi Y: Peritoneal macrophages which phagocytose autologous polymorphonuclear leucocytes in guinea pigs, I. Induction by irritants and microorganisms and inhibition by colchicine. Br J Exp Pathol 1982, 63:278-284
13. Savill J, Smith J, Sarraf C, Ren Y, Abbott F, Rees A: Glomerular mesangial cells and inflammatory macrophages ingest neutrophils undergoing apoptosis. Kidney Int 1992, 42:924-936
14. Barres BA, Hart IK, Coles HSR, Burne JF, Voyvodic JT, Richardson WD, Raff MC: Cell death and control of cell survival in the oligodendrocyte lineage, Cell 1992, 70:31-46
15. Coles HSR, Burne JF, Raff MC: Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor. Development (Camb) 1993, 118:777-784
16. Baker A, Mooney A, Hughes J, Lombardi D, Johnson RJ, Savill J: Mesangial cell apoptosis: the major mechanism for the resolution of glomerular hyperceliularity in experimental mesangial proliferative glomerulonephritis. J Clin Invest 1994, 94:2105-2116
17. Lan HY, Nikolic-Paterson DJ, Atkins RC: Trafficking of inflammatory macrophages from the kidney to draining lymph nodes during experimental glomerulonephritis. Clin Exp Irnmunol 1993, 92:336-341
18. Johnson RJ, Garcia RL, Pritzl P, Alpers CE: Platelets mediate glomerular cell proliferation in immune complex nephritis induced by anti-mesangial cell antibodies in the rat, Am J Pathol 1990, 136:369-374
19. Dijkstra CD, Dopp EA, Joling P, Kraal G: The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage populations in the rat recognised by monoclonal antibodies ED1, ED2, ED3, Immunology 1985, 54:589-599
20. Sekiya S, Gotoh S, Yamashita T, Watanabe T, Saitoh S, Sendo F: Selective depletion of rat neutrophils by In vivo administration of a monoclonal antibody, J Leukocyte Bio! 1989,46:96-102
21. 111 lndium tropolonate. Br J Radiol 1982, 55:247-249
22. Haslett C, Worthen GS, Giclas PC, Morrison DC: The pulmonary vascular sequestration of neutrophtls in endotoxemia is initiated by an effect of endotoxin on the neutrophil in the rabbit, Am Rev Respir Dis 1987, 136:9-18
23. Brown GM, Brown DM, Donaldson K, Drost E, MacNee W: Neutrophil sequestration in rat lungs. Thorax 1994, 50:661-667
24. Williams JH, Moser KM, Ulich T, Cairo MS: Harvesting the non-circulating pool of polymorphonuclear leukocytes in rats by hetastarch exchange transfusion (HET): yield and functional assessment. J Leukocyte Biol 1987, 42:455-462
25. Salant DJ, Darby C, Couser WG: Experimental membranous glomerulonephrits in rats: quantitative studies of glomerular immune deposit formation in isolated glomeruli and whole animals. J Clin Invest 1980, 66:71-81
26. Doherty DE, Downey GP, Worthen GS, Haslett C, Henson PM: Monocyte retention and migration in pulmonary inflammation. Lab Invest 1988, 59:200-213
27. Savill J, Dransfield I, Hogg N, Haslett C: Vitronectfn receptor mediated phagocytosis of cells undergoing apoptosis. Nature 1990, 343:170-173
28. Whyte MKB, Meagher LC, MacDermot J, Haslett C: Impairment of function in aging neutrophils is associated with apoptosis, J Immunol 1993, 150:5124-5134