Mainstream smoke chemistry analysis of samples from the 2009 US cigarette market

Regulatory Toxicology and Pharmacology

Volumn 64, Issue 1, 2012, Pages 35-42

  Bodnar, J A ^a   Morgan, W T ^a   Murphy, P A ^a   Ogden, M W ^a  

^a R J REYNOLDS TOBACCO COMPANY   (United States)

Author keywords

Cigarette; Mainstream smoke constituent; Survey; US market

Indexed keywords

1,3 BUTADIENE; 2 NAPHTHYLAMINE; 4 BIPHENYLAMINE; ACETALDEHYDE; ACROLEIN; ACRYLONITRILE; BENZENE; BENZO[A]PYRENE; CADMIUM; CARBON MONOXIDE; CATECHOL; CROTONALDEHYDE; FORMALDEHYDE; HYDROGEN CYANIDE; HYDROQUINONE; MENTHOL; NICOTINE; NITROGEN OXIDE; TAR;

ARTICLE; CHEMICAL COMPOSITION; CIGARETTE SMOKING; CONTROLLED STUDY; FILTER DESIGN; FILTRATION; PRIORITY JOURNAL; SMOKE; SOCIAL MARKETING; UNITED STATES;

DATA COLLECTION; HUMANS; SMOKE; TARS; TOBACCO; TOBACCO SMOKE POLLUTION; UNITED STATES;

EID: 84863829201     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2012.05.011     Document Type: Article

References (11)

1. Chepiga T.A., Morton M.J., Murphy P.A., Avalos J.T., Bombick B.R., Doolittle D.J., Borgerding M.F., Swauger J.E. A Comparison of the mainstream smoke chemistry and mutagenicity of a representative sample of the US cigarette market with two kentucky reference cigarettes (K1R4F and K1R5F). Food and Chemical Toxicology 2000, 38:949-962.
2. Counts M.E., Morton M.J., Laffoon S.W., Cox R.H., Lipowicz P.J. Smoke composition and predicting relationships for international commercial cigarettes smoked with three machine smoking conditions. Regulatory Toxicology and Pharmacology 2005, 41:185-227.
3. deBethizy, J., Bombick, B., Bombick, D., Swauger, J., Doolittle, D., 1998. The use of short-term tests to evaluate progress toward reducing the toxicity of cigarette smoke. Report of Canada's Expert Committee on Cigarette Toxicity Reduction, September 21-22.
4. Food and Drug Administration Center for Tobacco Products, Guidance for Industry Reporting Harmful and Potentially Harmful Constituents in Tobacco Products and Tobacco Smoke Under Section 904 (a) (3) of the Federal Food, Drug, and Cosmetic Act (March, 2012) available from: (accessed May 2012). http://www.fda.gov/downloads/TobaccoProducts/GuidanceComplianceRegulatoryInformation/UCM297828.pdf.
5. Hammond D., O'Conner R.J. Constituents in Tobacco and Smoke Emissions from Canadian Cigarettes. Tobacco Control 2008, 17(Suppl. l):i24-i31.
6. ISO8243-4:2006, Cigarette Sampling.
7. Smith C.J., Livingston S.D., Doolittle D.J. An international literature survey of " IARC Group I carcinogens" reported in mainstream cigarette smoke. Food and Chemical Toxicology 1997, 35(10-11):1107-1130.
8. Steele R.H., Payne V.M., Fulp C.W., Rees D.C., Lee C.K., Doolittle D.J. A comparison of the mutagenicity of mainstream cigarette smoke condensate from a representative sample of the US cigarette market with a kentucky reference cigarette (K1R4F). Mutation Research 1995, 342:179-190.
9. Swauger J.E., Morton M.J., Rahn C.A., Collie B.B., Bombick E.A., Avalos J.T., Doolittle D.J., Borgerding M.F., Rees D.C. A comparison of the mainstream cigarette smoke chemistry and mutagenicity of a representative sample of the US cigarette market with kentucky reference cigarettes K1R4F and K1R5F. Toxicologist 1997, 36(1):152.
10. Swauger J.E., Steichen T.J., Murphy P.A., Kinsler S. An analysis of mainstream smoke chemistry of samples of the US cigarette market acquired between 1995 and 2000. Regulatory Toxicology and Pharmacology 2002, 35:142-156.
11. WHO, 2008. The Scientific Basis of Tobacco Product Regulation: Second Report of a WHO Study Group. WHO Technical Report Series 951, World Health Organization, Geneva, Switzerland. Available from: (accessed May 2012). http://www.who.int/tobacco/global_interaction/tobreg/publications/tsr_951/en/.