-
1
-
-
0025765981
-
The toxicity of benzene and its metabolism and molecular pathology in human risk assessment
-
Yardley-Jones, A., D. Anderson, and D. V. Parke. The toxicity of benzene and its metabolism and molecular pathology in human risk assessment. Br. J. Ind. Med. 48:437-444 (1991).
-
(1991)
Br. J. Ind. Med.
, vol.48
, pp. 437-444
-
-
Yardley-Jones, A.1
Anderson, D.2
Parke, D.V.3
-
4
-
-
0028142345
-
Benzene metabolism by human liver microsomes in relation to cytochrome P450 2E1 activity
-
Seaton, M. J., P. M. Schlosser, J. A. Bond, and M. A. Medinsky. Benzene metabolism by human liver microsomes in relation to cytochrome P450 2E1 activity. Carcinogenesis 15:1799-1806 (1994).
-
(1994)
Carcinogenesis
, vol.15
, pp. 1799-1806
-
-
Seaton, M.J.1
Schlosser, P.M.2
Bond, J.A.3
Medinsky, M.A.4
-
5
-
-
0018646740
-
Benzene disposition in the rat after exposure by inhalation
-
Rickert, D. E., T. S. Baker, J. S. Bus, C. S. Barrow, and R. D. Irons. Benzene disposition in the rat after exposure by inhalation. Toxicol. Appl. Pharmacol. 49:417-423 (1979).
-
(1979)
Toxicol. Appl. Pharmacol.
, vol.49
, pp. 417-423
-
-
Rickert, D.E.1
Baker, T.S.2
Bus, J.S.3
Barrow, C.S.4
Irons, R.D.5
-
6
-
-
0019467474
-
A proposed mechanism of benzene toxicity: Formation of reactive intermediates from polyphenol metabolites
-
Greenlee, W. F., J. D. Sun, and J. S. Bus. A proposed mechanism of benzene toxicity: formation of reactive intermediates from polyphenol metabolites. Toxicol. Appl. Pharmacol. 59:187-195 (1981).
-
(1981)
Toxicol. Appl. Pharmacol.
, vol.59
, pp. 187-195
-
-
Greenlee, W.F.1
Sun, J.D.2
Bus, J.S.3
-
7
-
-
0025017521
-
Bone marrow stromal cell bioactivation and detoxification of the benzene metabolite hydroquinone: Comparison of macrophages and fibroblastoid cells
-
Thomas, D. J., A. Sadler, V. Subrahmanyam, D. Siegel, M. J. Reasor, D. Wierda, and D. Ross. Bone marrow stromal cell bioactivation and detoxification of the benzene metabolite hydroquinone: comparison of macrophages and fibroblastoid cells. Mol. Pharmacol. 37:255-262 (1990).
-
(1990)
Mol. Pharmacol.
, vol.37
, pp. 255-262
-
-
Thomas, D.J.1
Sadler, A.2
Subrahmanyam, V.3
Siegel, D.4
Reasor, M.J.5
Wierda, D.6
Ross, D.7
-
8
-
-
0022323885
-
Quinones as toxic metabolites of benzene
-
Irons, R. D. Quinones as toxic metabolites of benzene. J. Toxicol. Environ. Health 16:673-678 (1985).
-
(1985)
J. Toxicol. Environ. Health
, vol.16
, pp. 673-678
-
-
Irons, R.D.1
-
9
-
-
0027517496
-
Peroxidase activation of hydroquinone results in the formation of DNA adducts in HL-60 cells, mouse bone marrow macrophages and human bone marrow
-
Levay, G., D. Ross, and W. J. Bodell. Peroxidase activation of hydroquinone results in the formation of DNA adducts in HL-60 cells, mouse bone marrow macrophages and human bone marrow. Carcinogenesis 14:2329-2334 (1993).
-
(1993)
Carcinogenesis
, vol.14
, pp. 2329-2334
-
-
Levay, G.1
Ross, D.2
Bodell, W.J.3
-
10
-
-
0027408743
-
Benzene and its phenolic metabolites produce oxidative DNA damage in HL60 cells in vitro and in the bone marrow in vivo
-
Kolachana, P., V. V. Subrahmanyam, K. B. Meyer, L. Zhang, and M. T. Smith. Benzene and its phenolic metabolites produce oxidative DNA damage in HL60 cells in vitro and in the bone marrow in vivo. Cancer Res. 53:1023-1026 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 1023-1026
-
-
Kolachana, P.1
Subrahmanyam, V.V.2
Meyer, K.B.3
Zhang, L.4
Smith, M.T.5
-
11
-
-
0028610410
-
Bioactivation of quinones by DT-diaphorase, molecular, biochemical, and chemical studies
-
Ross, D., H. Beall, R. D. Traver, D. Siegel, R. M. Phillips, and N. W. Gibson. Bioactivation of quinones by DT-diaphorase, molecular, biochemical, and chemical studies. Oncol. Res. 6:493-500 (1994).
-
(1994)
Oncol. Res.
, vol.6
, pp. 493-500
-
-
Ross, D.1
Beall, H.2
Traver, R.D.3
Siegel, D.4
Phillips, R.M.5
Gibson, N.W.6
-
12
-
-
0027055783
-
Cell-specific metabolism in mouse bone marrow stroma: Studies of activation and detoxification of benzene metabolites
-
Ganousis, L. G., D. Goon, T. Zyglewska, K. K. Wu, and D. Ross. Cell-specific metabolism in mouse bone marrow stroma: studies of activation and detoxification of benzene metabolites. Mol. Pharmacol. 42:1118-1125 (1992).
-
(1992)
Mol. Pharmacol.
, vol.42
, pp. 1118-1125
-
-
Ganousis, L.G.1
Goon, D.2
Zyglewska, T.3
Wu, K.K.4
Ross, D.5
-
13
-
-
0024503765
-
Macrophage regulation of myelopoiesis is altered by exposure to the benzene metabolite hydroquinone
-
Thomas, D. J., M. J. Reasor, and D. Wierda. Macrophage regulation of myelopoiesis is altered by exposure to the benzene metabolite hydroquinone. Toxicol. Appl. Pharmacol. 97:440-453 (1989).
-
(1989)
Toxicol. Appl. Pharmacol.
, vol.97
, pp. 440-453
-
-
Thomas, D.J.1
Reasor, M.J.2
Wierda, D.3
-
14
-
-
0019453973
-
Acute and chronic dose/response effects of inhaled benzene on multipotential hematopoietic stem (CFU-S) and granulocyte/macrophage progenitor (GM-CFU-C) cells in CD-1 mice
-
Green, J. D., C. A. Snyder, J. LoBue, B. D. Goldstein, and R. E. Albert. Acute and chronic dose/response effects of inhaled benzene on multipotential hematopoietic stem (CFU-S) and granulocyte/macrophage progenitor (GM-CFU-C) cells in CD-1 mice. Toxicol. Appl. Pharmacol. 58:492-503 (1981).
-
(1981)
Toxicol. Appl. Pharmacol.
, vol.58
, pp. 492-503
-
-
Green, J.D.1
Snyder, C.A.2
LoBue, J.3
Goldstein, B.D.4
Albert, R.E.5
-
15
-
-
0019954263
-
Effects of benzene inhalation on murine pluripotent stem cells
-
Cronkite, E. P., T. Inoue, A. L. Carsten, M. E. Miller, J. E. Bullis, and R. T. Drew. Effects of benzene inhalation on murine pluripotent stem cells. J. Toxicol. Environ. Health 9:411-421 (1982).
-
(1982)
J. Toxicol. Environ. Health
, vol.9
, pp. 411-421
-
-
Cronkite, E.P.1
Inoue, T.2
Carsten, A.L.3
Miller, M.E.4
Bullis, J.E.5
Drew, R.T.6
-
17
-
-
0028998582
-
Isolation of small, primitive human hematopoietic stem cells: Distribution of cell surface cytokine receptors and growth in SCID-Hu mice
-
Wagner, J. E., D. Collins, S. Fuller, L. R. Schain, A. E. Berson, C. Almici, M. A. Hall, K. E. Chen, T. B. Okarma, and J. S. Lebkowski. Isolation of small, primitive human hematopoietic stem cells: distribution of cell surface cytokine receptors and growth in SCID-Hu mice. Blood 86:512-523 (1995).
-
(1995)
Blood
, vol.86
, pp. 512-523
-
-
Wagner, J.E.1
Collins, D.2
Fuller, S.3
Schain, L.R.4
Berson, A.E.5
Almici, C.6
Hall, M.A.7
Chen, K.E.8
Okarma, T.B.9
Lebkowski, J.S.10
-
18
-
-
0025838078
-
+ HLA-DR- bone marrow cells contain progenitor cells capable of self-renewal, multilineage differentiation, and long-term in vitro hematopoiesis
-
+ HLA-DR- bone marrow cells contain progenitor cells capable of self-renewal, multilineage differentiation, and long-term in vitro hematopoiesis. Blood Cells 17:287-295 (1991).
-
(1991)
Blood Cells
, vol.17
, pp. 287-295
-
-
Srour, E.F.1
Brandt, J.E.2
Briddell, R.A.3
Leemhuis, T.4
Van Besien, K.5
Hoffman, R.6
-
20
-
-
0028026727
-
Peroxidase activity in murine and human hematopoietic progenitor cells: Potential relevance to benzene-induced toxicity
-
Schattenberg, D. G., W. S. Stillman, J. J. Gruntmeir, K. M. Helm, R. D. Irons, and D. Ross. Peroxidase activity in murine and human hematopoietic progenitor cells: potential relevance to benzene-induced toxicity. Mol. Pharmacol. 46:346-351 (1994).
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 346-351
-
-
Schattenberg, D.G.1
Stillman, W.S.2
Gruntmeir, J.J.3
Helm, K.M.4
Irons, R.D.5
Ross, D.6
-
21
-
-
0028670377
-
Cell death in the myeloid lineage
-
Cotter, T. G., R. S. Fernandes, S. Verhaegen, and J. V. McCarthy. Cell death in the myeloid lineage. Immunol. Rev. 142:93-112 (1994).
-
(1994)
Immunol. Rev.
, vol.142
, pp. 93-112
-
-
Cotter, T.G.1
Fernandes, R.S.2
Verhaegen, S.3
McCarthy, J.V.4
-
22
-
-
0028670379
-
Lymphocyte apoptosis-mechanisms and implications in disease
-
Howie, S. E. M., D. J. Harrison, and A. H. Wyllie. Lymphocyte apoptosis-mechanisms and implications in disease. Immunol. Rev. 142:141-153 (1994).
-
(1994)
Immunol. Rev.
, vol.142
, pp. 141-153
-
-
Howie, S.E.M.1
Harrison, D.J.2
Wyllie, A.H.3
-
23
-
-
0027269557
-
Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays
-
Gorczyca, W., J. Gong, and Z. Darzynkiewicz. Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res. 53:1945-1951 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 1945-1951
-
-
Gorczyca, W.1
Gong, J.2
Darzynkiewicz, Z.3
-
24
-
-
0027479655
-
Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation
-
Brown, D. G., X.-M. Sun, and G. M. Cohen. Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. J. Biol. Chem. 268:3037-3039 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 3037-3039
-
-
Brown, D.G.1
Sun, X.-M.2
Cohen, G.M.3
-
25
-
-
0025131538
-
Activation and deactivation of quinones catalyzed by DT-diaphorase: Evidence for bioreductive activation of diaziquone (AZQ) in human tumor cells and detoxification of benzene metabolites in bone marrow stroma
-
Ross, D., D. Siegel, N. W. Gibson, D. Pacheco, D. J. Thomas, M. Reasor, and D. Wierda. Activation and deactivation of quinones catalyzed by DT-diaphorase: evidence for bioreductive activation of diaziquone (AZQ) in human tumor cells and detoxification of benzene metabolites in bone marrow stroma. Free Radical Res. Commun. 8:373-381 (1990).
-
(1990)
Free Radical Res. Commun.
, vol.8
, pp. 373-381
-
-
Ross, D.1
Siegel, D.2
Gibson, N.W.3
Pacheco, D.4
Thomas, D.J.5
Reasor, M.6
Wierda, D.7
-
26
-
-
0026538306
-
Induction of quinone reductase and glutathione in bone marrow cells by 1,2-dithiole-3-thione: Effect on hydroquinone-induced cytotoxicity
-
Twerdock, L. E., S. J. Rembish, and M. A. Trush. Induction of quinone reductase and glutathione in bone marrow cells by 1,2-dithiole-3-thione: effect on hydroquinone-induced cytotoxicity. Toxicol. Appl. Pharmacol. 112:273-281 (1992).
-
(1992)
Toxicol. Appl. Pharmacol.
, vol.112
, pp. 273-281
-
-
Twerdock, L.E.1
Rembish, S.J.2
Trush, M.A.3
-
27
-
-
0025822724
-
Metabolism of hydroquinone by human myeloperoxidase: Mechanisms of stimulation by other phenolic compounds
-
Subrahmanyam, V. V., P. Kolachana, and M. T. Smith. Metabolism of hydroquinone by human myeloperoxidase: mechanisms of stimulation by other phenolic compounds. Arch. Biochem. Biophys. 286:76-84 (1991).
-
(1991)
Arch. Biochem. Biophys.
, vol.286
, pp. 76-84
-
-
Subrahmanyam, V.V.1
Kolachana, P.2
Smith, M.T.3
-
28
-
-
84907036679
-
Is apoptosis mediated by reactive oxygen species?
-
Sarafian, T. A., and D. E. Bredesen. Is apoptosis mediated by reactive oxygen species? Free Radical Res. 21:1-8 (1994).
-
(1994)
Free Radical Res.
, vol.21
, pp. 1-8
-
-
Sarafian, T.A.1
Bredesen, D.E.2
-
31
-
-
0029059073
-
The treatment of severe acquired aplastic anemia
-
Young, N. S., and A. J. Barrett. The treatment of severe acquired aplastic anemia. Blood 85:3367-3377 (1995).
-
(1995)
Blood
, vol.85
, pp. 3367-3377
-
-
Young, N.S.1
Barrett, A.J.2
-
32
-
-
0029032805
-
Aplastic anemia
-
Young, N. S. Aplastic anemia. Lancet 1:228-232 (1995).
-
(1995)
Lancet
, vol.1
, pp. 228-232
-
-
Young, N.S.1
-
33
-
-
0028246610
-
Haemopoietic progenitor cells are reduced in aplastic anemia
-
Scopes, J., M. Bagnara, E. C. Gordon-Smith, S. E. Ball, and F. M. Gibson. Haemopoietic progenitor cells are reduced in aplastic anemia. Br. J. Haematol. 86:427-430 (1994).
-
(1994)
Br. J. Haematol.
, vol.86
, pp. 427-430
-
-
Scopes, J.1
Bagnara, M.2
Gordon-Smith, E.C.3
Ball, S.E.4
Gibson, F.M.5
-
34
-
-
0025880606
-
In vitro assessment of marrow 'stem cell' and stromal cell function in aplastic anemia
-
Marsh, J. C. W., J. Chang, N. G. Testa, J. M. Hows, and T. M. Dexter. In vitro assessment of marrow 'stem cell' and stromal cell function in aplastic anemia. Br. J. Haematol. 78:258-267 (1991).
-
(1991)
Br. J. Haematol.
, vol.78
, pp. 258-267
-
-
Marsh, J.C.W.1
Chang, J.2
Testa, N.G.3
Hows, J.M.4
Dexter, T.M.5
-
35
-
-
0028930939
-
Simultaneous assessment of cell kinetics and programmed cell death in bone marrow biopsies of myelodysplastics reveals extensive apoptosis as the probable basis for ineffective hematopoiesis
-
Raza, A., S. Mundle, A. Iftikhar, S. Gregory, B. Marcus, Z. Khan, S. Alvi, V. Shetty, S. Dameron, V. Wright, S. Adler, J. M. Loew, S. Shott, S. N. Ali, and H. Preisler. Simultaneous assessment of cell kinetics and programmed cell death in bone marrow biopsies of myelodysplastics reveals extensive apoptosis as the probable basis for ineffective hematopoiesis. Am. J. Hematol. 48:143-154 (1995).
-
(1995)
Am. J. Hematol.
, vol.48
, pp. 143-154
-
-
Raza, A.1
Mundle, S.2
Iftikhar, A.3
Gregory, S.4
Marcus, B.5
Khan, Z.6
Alvi, S.7
Shetty, V.8
Dameron, S.9
Wright, V.10
Adler, S.11
Loew, J.M.12
Shott, S.13
Ali, S.N.14
Preisler, H.15
-
36
-
-
0027360514
-
Malignant tumors occurring after treatment of aplastic anemia
-
Socie, G., M. Henry-Amar, A. Bacigalupo, J. Hows, A. Tichelli, P. Ljungman, S. R. McCann, N. Frickhofen, E. V. T. Veer-Korthof, and E. Gluckman. Malignant tumors occurring after treatment of aplastic anemia. N. Engl. J. Med. 329:1152-1157 (1993).
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 1152-1157
-
-
Socie, G.1
Henry-Amar, M.2
Bacigalupo, A.3
Hows, J.4
Tichelli, A.5
Ljungman, P.6
McCann, S.R.7
Frickhofen, N.8
Veer-Korthof, E.V.T.9
Gluckman, E.10
-
37
-
-
0025908316
-
Is aplastic anemia a pre-leukemic disorder?
-
Marsh, J. C. W., and C. G. Geary. Is aplastic anemia a pre-leukemic disorder? Br. J. Haematol. 77:447-452 (1991).
-
(1991)
Br. J. Haematol.
, vol.77
, pp. 447-452
-
-
Marsh, J.C.W.1
Geary, C.G.2
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