메뉴 건너뛰기




Volumn 63, Issue 3, 2014, Pages 185-195

The immune system and the remodeling infarcted heart: Cell biological insights and therapeutic opportunities

Author keywords

Cardiac remodeling; Chemokines; Cytokines; Innate immunity; Leukocytes; Myocardial infarction; Toll like receptors

Indexed keywords

GROWTH DIFFERENTIATION FACTOR 15; INTERLEUKIN 10; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR 3;

EID: 84896318665     PISSN: 01602446     EISSN: 15334023     Source Type: Journal    
DOI: 10.1097/FJC.0000000000000003     Document Type: Review
Times cited : (137)

References (92)
  • 1
    • 33847724471 scopus 로고    scopus 로고
    • The mechanistic basis of infarct healing
    • Frangogiannis NG. The mechanistic basis of infarct healing. Antioxid Redox Signal. 2006;8:1907-1939
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1907-1939
    • Frangogiannis, N.G.1
  • 2
    • 53249095498 scopus 로고    scopus 로고
    • The immune system and cardiac repair
    • Frangogiannis NG. The immune system and cardiac repair. Pharmacol Res. 2008;58:88-111
    • (2008) Pharmacol Res , vol.58 , pp. 88-111
    • Frangogiannis, N.G.1
  • 3
    • 84855371090 scopus 로고    scopus 로고
    • Regulation of the inflammatory response in cardiac repair
    • Frangogiannis NG. Regulation of the inflammatory response in cardiac repair. Circ Res. 2012;110:159-173
    • (2012) Circ Res , vol.110 , pp. 159-173
    • Frangogiannis, N.G.1
  • 4
    • 59449085857 scopus 로고    scopus 로고
    • Post-infarct remodelling: Contribution of wound healing and inflammation
    • Frantz S, Bauersachs J, Ertl G. Post-infarct remodelling: Contribution of wound healing and inflammation. Cardiovasc Res. 2009;81:474-481
    • (2009) Cardiovasc Res , vol.81 , pp. 474-481
    • Frantz, S.1    Bauersachs, J.2    Ertl, G.3
  • 5
    • 0025944661 scopus 로고
    • Inflammation in the course of early myocardial ischemia
    • Entman ML, Michael L, Rossen RD, et al. Inflammation in the course of early myocardial ischemia. FASEB J. 1991;5:2529-2537
    • (1991) FASEB J. , vol.5 , pp. 2529-2537
    • Entman, M.L.1    Michael, L.2    Rossen, R.D.3
  • 6
    • 0037010009 scopus 로고    scopus 로고
    • The effect of blockade of the CD11/CD18 integrin receptor on infarct size in patients with acute myocardial infarction treated with direct angioplasty: The results of the HALT-MI study
    • Faxon DP, Gibbons RJ, Chronos NA, et al. The effect of blockade of the CD11/CD18 integrin receptor on infarct size in patients with acute myocardial infarction treated with direct angioplasty: The results of the HALT-MI study. J Am Coll Cardiol. 2002;40:1199-1204
    • (2002) J Am Coll Cardiol , vol.40 , pp. 1199-1204
    • Faxon, D.P.1    Gibbons, R.J.2    Chronos, N.A.3
  • 7
    • 33845981823 scopus 로고    scopus 로고
    • Pexelizumab for acute ST-elevation myocardial infarction in patients undergoing primary percutaneous coronary intervention: A randomized controlled trial
    • Armstrong PW, Granger CB, Adams PX, et al. Pexelizumab for acute ST-elevation myocardial infarction in patients undergoing primary percutaneous coronary intervention: A randomized controlled trial. JAMA. 2007;297:43-51
    • (2007) JAMA , vol.297 , pp. 43-51
    • Armstrong, P.W.1    Granger, C.B.2    Adams, P.X.3
  • 8
    • 0017643309 scopus 로고
    • The wavefront phenomenon of ischemic cell death 1 Myocardial infarct size vs duration of coronary occlusion in dogs
    • Reimer KA, Lowe JE, Rasmussen MM, et al. The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs duration of coronary occlusion in dogs. Circulation. 1977;56:786-794
    • (1977) Circulation , Issue.56 , pp. 786-794
    • Reimer, K.A.1    Lowe, J.E.2    Rasmussen, M.M.3
  • 9
    • 84860112830 scopus 로고    scopus 로고
    • The innate immune response in reperfused myocardium
    • Timmers L, Pasterkamp G, de Hoog VC, et al. The innate immune response in reperfused myocardium. Cardiovasc Res. 2012;94:276-283
    • (2012) Cardiovasc Res , vol.94 , pp. 276-283
    • Timmers, L.1    Pasterkamp, G.2    De Hoog, V.C.3
  • 10
    • 51649111202 scopus 로고    scopus 로고
    • High-mobility group box-1 in ischemia-reperfusion injury of the heart
    • Andrassy M, Volz HC, Igwe JC, et al. High-mobility group box-1 in ischemia-reperfusion injury of the heart. Circulation. 2008;117:3216-3226
    • (2008) Circulation , vol.117 , pp. 3216-3226
    • Andrassy, M.1    Volz, H.C.2    Igwe, J.C.3
  • 12
    • 42149091690 scopus 로고    scopus 로고
    • CD44 is critically involved in infarct healing by regulating the inflammatory and fibrotic response
    • Huebener P, Abou-Khamis T, Zymek P, et al. CD44 is critically involved in infarct healing by regulating the inflammatory and fibrotic response. J Immunol. 2008;180:2625-2633
    • (2008) J Immunol , vol.180 , pp. 2625-2633
    • Huebener, P.1    Abou-Khamis, T.2    Zymek, P.3
  • 13
    • 77649276038 scopus 로고    scopus 로고
    • The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction
    • Dobaczewski M, Gonzalez-Quesada C, Frangogiannis NG. The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction. J Mol Cell Cardiol. 2010; 48:504-511
    • (2010) J Mol Cell Cardiol , vol.48 , pp. 504-511
    • Dobaczewski, M.1    Gonzalez-Quesada, C.2    Frangogiannis, N.G.3
  • 14
    • 1242336786 scopus 로고    scopus 로고
    • Reduced myocardial ischemiareperfusion injury in toll-like receptor 4-deficient mice
    • Oyama J, Blais C Jr, Liu X, et al. Reduced myocardial ischemiareperfusion injury in toll-like receptor 4-deficient mice. Circulation. 2004;109:784-789
    • (2004) Circulation , vol.109 , pp. 784-789
    • Oyama, J.1    Blais Jr., C.2    Liu, X.3
  • 15
    • 41149165830 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction
    • Timmers L, Sluijter JP, van Keulen JK, et al. Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction. Circ Res. 2008;102:257-264
    • (2008) Circ Res , vol.102 , pp. 257-264
    • Timmers, L.1    Sluijter, J.P.2    Van Keulen, J.K.3
  • 16
    • 74549178528 scopus 로고    scopus 로고
    • Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibody
    • Arslan F, Smeets MB, O'Neill LA, et al. Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibody. Circulation. 2010;121:80-90
    • (2010) Circulation , vol.121 , pp. 80-90
    • Arslan, F.1    Smeets, M.B.2    O'Neill, L.A.3
  • 17
    • 0015042034 scopus 로고
    • The phlogistic role of C3 leukotactic fragments in myocardial infarcts of rats
    • Hill JH, Ward PA. The phlogistic role of C3 leukotactic fragments in myocardial infarcts of rats. J Exp Med. 1971;133:885-900
    • (1971) J Exp Med , vol.133 , pp. 885-900
    • Hill, J.H.1    Ward, P.A.2
  • 18
    • 0025354456 scopus 로고
    • Soluble human complement receptor type 1: In vivo inhibitor of complement suppressing post-ischemic myocardial inflammation and necrosis
    • Weisman HF, Bartow T, Leppo MK, et al. Soluble human complement receptor type 1: In vivo inhibitor of complement suppressing post-ischemic myocardial inflammation and necrosis. Science. 1990;249:146-151
    • (1990) Science , vol.249 , pp. 146-151
    • Weisman, H.F.1    Bartow, T.2    Leppo, M.K.3
  • 19
    • 0024203618 scopus 로고
    • Role of xanthine oxidase and granulocytes in ischemiareperfusion injury
    • Granger DN. Role of xanthine oxidase and granulocytes in ischemiareperfusion injury. Am J Physiol. 1988;255(6 pt 2):H1269-H1275
    • (1988) Am J Physiol , vol.255 , Issue.6 PART 2
    • Granger, D.N.1
  • 20
    • 0034656849 scopus 로고    scopus 로고
    • Reactive oxygen species, cell signaling, and cell injury
    • Hensley K, Robinson KA, Gabbita SP, et al. Reactive oxygen species, cell signaling, and cell injury. Free Radic Biol Med. 2000;28:1456-1462
    • (2000) Free Radic Biol Med , vol.28 , pp. 1456-1462
    • Hensley, K.1    Robinson, K.A.2    Gabbita, S.P.3
  • 21
    • 79955605472 scopus 로고    scopus 로고
    • Multiple facets of NF-kappaB in the heart: To be or not to NF-kappaB
    • Gordon JW, Shaw JA, Kirshenbaum LA. Multiple facets of NF-kappaB in the heart: To be or not to NF-kappaB. Circ Res. 2011;108:1122-1132
    • (2011) Circ Res , vol.108 , pp. 1122-1132
    • Gordon, J.W.1    Shaw, J.A.2    Kirshenbaum, L.A.3
  • 22
    • 3042702881 scopus 로고    scopus 로고
    • Inflammatory cytokines and postmyocardial infarction remodeling
    • Nian M, Lee P, Khaper N, et al. Inflammatory cytokines and postmyocardial infarction remodeling. Circ Res. 2004;94:1543-1553
    • (2004) Circ Res , vol.94 , pp. 1543-1553
    • Nian, M.1    Lee, P.2    Khaper, N.3
  • 23
    • 46749144616 scopus 로고    scopus 로고
    • Interleukin-1 receptor type i signaling critically regulates infarct healing and cardiac remodeling
    • Bujak M, Dobaczewski M, Chatila K, et al. Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling. Am J Pathol. 2008;173:57-67
    • (2008) Am J Pathol , vol.173 , pp. 57-67
    • Bujak, M.1    Dobaczewski, M.2    Chatila, K.3
  • 24
  • 25
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K, Tschopp J. The inflammasomes. Cell. 2010;140:821-832
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 26
    • 83755195135 scopus 로고    scopus 로고
    • The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse
    • Mezzaroma E, Toldo S, Farkas D, et al. The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse. Proc Natl Acad Sci USA. 2011;108:19725-19730
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 19725-19730
    • Mezzaroma, E.1    Toldo, S.2    Farkas, D.3
  • 27
    • 79951679204 scopus 로고    scopus 로고
    • Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury
    • Kawaguchi M, Takahashi M, Hata T, et al. Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury. Circulation. 2011;123:594-604
    • (2011) Circulation , vol.123 , pp. 594-604
    • Kawaguchi, M.1    Takahashi, M.2    Hata, T.3
  • 28
    • 0032544201 scopus 로고    scopus 로고
    • Resident cardiac mast cells degranulate and release preformed TNF-alpha, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion
    • Frangogiannis NG, Lindsey ML, Michael LH, et al. Resident cardiac mast cells degranulate and release preformed TNF-alpha, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion. Circulation. 1998;98:699-710
    • (1998) Circulation , vol.98 , pp. 699-710
    • Frangogiannis, N.G.1    Lindsey, M.L.2    Michael, L.H.3
  • 29
    • 0034625134 scopus 로고    scopus 로고
    • Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemicinduced apoptosis in a murine model of acute myocardial infarction
    • Kurrelmeyer KM, Michael LH, Baumgarten G, et al. Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemicinduced apoptosis in a murine model of acute myocardial infarction. Proc Natl Acad Sci USA. 2000;97:5456-5461
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5456-5461
    • Kurrelmeyer, K.M.1    Michael, L.H.2    Baumgarten, G.3
  • 30
    • 64549087652 scopus 로고    scopus 로고
    • Divergent tumor necrosis factor receptor-related remodeling responses in heart failure: Role of nuclear factor-kappaB and inflammatory activation
    • Hamid T, Gu Y, Ortines RV, et al. Divergent tumor necrosis factor receptor-related remodeling responses in heart failure: Role of nuclear factor-kappaB and inflammatory activation. Circulation. 2009;119: 1386-1397
    • (2009) Circulation , vol.119 , pp. 1386-1397
    • Hamid, T.1    Gu, Y.2    Ortines, R.V.3
  • 31
    • 40349100263 scopus 로고    scopus 로고
    • Role of gp130-mediated signalling pathways in the heart and its impact on potential therapeutic aspects
    • Fischer P, Hilfiker-Kleiner D. Role of gp130-mediated signalling pathways in the heart and its impact on potential therapeutic aspects. Br J Pharmacol. 2008;153(suppl 1)S414-S427
    • (2008) Br J Pharmacol , vol.153 , Issue.SUPPL. . 1
    • Fischer, P.1    Hilfiker-Kleiner, D.2
  • 32
    • 0642273060 scopus 로고    scopus 로고
    • Role of interleukin-6 for LV remodeling and survival after experimental myocardial infarction
    • Fuchs M, Hilfiker A, Kaminski K, et al. Role of interleukin-6 for LV remodeling and survival after experimental myocardial infarction. FASEB J. 2003;17:2118-2120
    • (2003) FASEB J. , vol.17 , pp. 2118-2120
    • Fuchs, M.1    Hilfiker, A.2    Kaminski, K.3
  • 33
    • 77954781995 scopus 로고    scopus 로고
    • Antibody against interleukin-6 receptor attenuates left ventricular remodelling after myocardial infarction in mice
    • Kobara M, Noda K, Kitamura M, et al. Antibody against interleukin-6 receptor attenuates left ventricular remodelling after myocardial infarction in mice. Cardiovasc Res. 2010;87:424-430
    • (2010) Cardiovasc Res , vol.87 , pp. 424-430
    • Kobara, M.1    Noda, K.2    Kitamura, M.3
  • 34
    • 77954762928 scopus 로고    scopus 로고
    • Continuous glycoprotein- 130-mediated signal transducer and activator of transcription-3 activation promotes inflammation, left ventricular rupture, and adverse outcome in subacute myocardial infarction
    • Hilfiker-Kleiner D, Shukla P, Klein G, et al. Continuous glycoprotein- 130-mediated signal transducer and activator of transcription-3 activation promotes inflammation, left ventricular rupture, and adverse outcome in subacute myocardial infarction. Circulation. 2010;122:145-155
    • (2010) Circulation , vol.122 , pp. 145-155
    • Hilfiker-Kleiner, D.1    Shukla, P.2    Klein, G.3
  • 35
    • 34249008096 scopus 로고    scopus 로고
    • Chemokines in ischemia and reperfusion
    • Frangogiannis NG. Chemokines in ischemia and reperfusion. Thromb Haemost. 2007;97:738-747
    • (2007) Thromb Haemost , vol.97 , pp. 738-747
    • Frangogiannis, N.G.1
  • 36
    • 36549033197 scopus 로고    scopus 로고
    • The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
    • Nahrendorf M, Swirski FK, Aikawa E, et al. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med. 2007;204:3037-3047
    • (2007) J Exp Med , vol.204 , pp. 3037-3047
    • Nahrendorf, M.1    Swirski, F.K.2    Aikawa, E.3
  • 37
    • 77952065445 scopus 로고    scopus 로고
    • CCR5 signaling suppresses inflammation and reduces adverse remodeling of the infarcted heart, mediating recruitment of regulatory T cells
    • Dobaczewski M, Xia Y, Bujak M, et al. CCR5 signaling suppresses inflammation and reduces adverse remodeling of the infarcted heart, mediating recruitment of regulatory T cells. Am J Pathol. 2010;176: 2177-2187
    • (2010) Am J Pathol , vol.176 , pp. 2177-2187
    • Dobaczewski, M.1    Xia, Y.2    Bujak, M.3
  • 38
    • 0037452728 scopus 로고    scopus 로고
    • Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines
    • Proudfoot AE, Handel TM, Johnson Z, et al. Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines. Proc Natl Acad Sci USA. 2003;100:1885-1890
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1885-1890
    • Proudfoot, A.E.1    Handel, T.M.2    Johnson, Z.3
  • 39
    • 80053298261 scopus 로고    scopus 로고
    • Emerging mechanisms of neutrophil recruitment across endothelium
    • Williams MR, Azcutia V, Newton G, et al. Emerging mechanisms of neutrophil recruitment across endothelium. Trends Immunol. 2011;32: 461-469
    • (2011) Trends Immunol , vol.32 , pp. 461-469
    • Williams, M.R.1    Azcutia, V.2    Newton, G.3
  • 40
    • 80052026271 scopus 로고    scopus 로고
    • The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo
    • Woodfin A, Voisin MB, Beyrau M, et al. The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo. Nat Immunol. 2011;12:761-769
    • (2011) Nat Immunol , vol.12 , pp. 761-769
    • Woodfin, A.1    Voisin, M.B.2    Beyrau, M.3
  • 41
    • 23044465208 scopus 로고    scopus 로고
    • Junctional adhesion molecule-Adeficient polymorphonuclear cells show reduced diapedesis in peritonitis and heart ischemia-reperfusion injury
    • Corada M, Chimenti S, Cera MR, et al. Junctional adhesion molecule-Adeficient polymorphonuclear cells show reduced diapedesis in peritonitis and heart ischemia-reperfusion injury. Proc Natl Acad Sci USA. 2005; 102:10634-10639
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 10634-10639
    • Corada, M.1    Chimenti, S.2    Cera, M.R.3
  • 42
    • 33846118743 scopus 로고    scopus 로고
    • Platelets as immune cells: Bridging inflammation and cardiovascular disease
    • von Hundelshausen P, Weber C. Platelets as immune cells: Bridging inflammation and cardiovascular disease. Circ Res. 2007;100:27-40
    • (2007) Circ Res , vol.100 , pp. 27-40
    • Von Hundelshausen, P.1    Weber, C.2
  • 43
    • 33646373473 scopus 로고    scopus 로고
    • Extracellular matrix remodeling in canine and mouse myocardial infarcts
    • Dobaczewski M, Bujak M, Zymek P, et al. Extracellular matrix remodeling in canine and mouse myocardial infarcts. Cell Tissue Res. 2006; 324:475-488
    • (2006) Cell Tissue Res , vol.324 , pp. 475-488
    • Dobaczewski, M.1    Bujak, M.2    Zymek, P.3
  • 44
    • 0028231065 scopus 로고
    • Adhesion molecules and inflammatory injury
    • Albelda SM, Smith CW, Ward PA. Adhesion molecules and inflammatory injury. FASEB J. 1994;8:504-512
    • (1994) FASEB J. , vol.8 , pp. 504-512
    • Albelda, S.M.1    Smith, C.W.2    Ward, P.A.3
  • 45
    • 0035253788 scopus 로고    scopus 로고
    • Mouse model of myocardial remodelling after ischemia: Role of intercellular adhesion molecule-1
    • Metzler B, Mair J, Lercher A, et al. Mouse model of myocardial remodelling after ischemia: Role of intercellular adhesion molecule-1. Cardiovasc Res. 2001;49:399-407
    • (2001) Cardiovasc Res , vol.49 , pp. 399-407
    • Metzler, B.1    Mair, J.2    Lercher, A.3
  • 46
    • 0035019511 scopus 로고    scopus 로고
    • Leukocyte trafficking and myocardial reperfusion injury in ICAM-1/P-selectin-knockout mice
    • Briaud SA, Ding ZM, Michael LH, et al. Leukocyte trafficking and myocardial reperfusion injury in ICAM-1/P-selectin-knockout mice. Am J Physiol Heart Circ Physiol. 2001;280:H60-H67
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Briaud, S.A.1    Ding, Z.M.2    Michael, L.H.3
  • 47
    • 68149119072 scopus 로고    scopus 로고
    • Identification of splenic reservoir monocytes and their deployment to inflammatory sites
    • Swirski FK, Nahrendorf M, Etzrodt M, et al. Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science. 2009;325:612-616
    • (2009) Science , vol.325 , pp. 612-616
    • Swirski, F.K.1    Nahrendorf, M.2    Etzrodt, M.3
  • 48
    • 84875214942 scopus 로고    scopus 로고
    • Endoscopic time-lapse imaging of immune cells in infarcted mouse hearts
    • Jung K, Kim P, Leuschner F, et al. Endoscopic time-lapse imaging of immune cells in infarcted mouse hearts. Circ Res. 2013;112:891-899
    • (2013) Circ Res , vol.112 , pp. 891-899
    • Jung, K.1    Kim, P.2    Leuschner, F.3
  • 49
    • 20944449211 scopus 로고    scopus 로고
    • CCL2/monocyte chemoattractant protein-1 regulates inflammatory responses critical to healing myocardial infarcts
    • Dewald O, Zymek P, Winkelmann K, et al. CCL2/monocyte chemoattractant protein-1 regulates inflammatory responses critical to healing myocardial infarcts. Circ Res. 2005;96:881-889
    • (2005) Circ Res , vol.96 , pp. 881-889
    • Dewald, O.1    Zymek, P.2    Winkelmann, K.3
  • 50
    • 0037962287 scopus 로고    scopus 로고
    • MCSF expression is induced in healing myocardial infarcts and may regulate monocyte and endothelial cell phenotype
    • Frangogiannis NG, Mendoza LH, Ren G, et al. MCSF expression is induced in healing myocardial infarcts and may regulate monocyte and endothelial cell phenotype. Am J Physiol Heart Circ Physiol. 2003;285: H483-H492
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Frangogiannis, N.G.1    Mendoza, L.H.2    Ren, G.3
  • 51
    • 0036315811 scopus 로고    scopus 로고
    • Mast cells and macrophages in normal C57/BL/6 mice
    • Gersch C, Dewald O, Zoerlein M, et al. Mast cells and macrophages in normal C57/BL/6 mice. Histochem Cell Biol. 2002;118:41-49
    • (2002) Histochem Cell Biol , vol.118 , pp. 41-49
    • Gersch, C.1    Dewald, O.2    Zoerlein, M.3
  • 52
    • 73349122017 scopus 로고    scopus 로고
    • Cardiac fibroblast: The renaissance cell
    • Souders CA, Bowers SL, Baudino TA. Cardiac fibroblast: The renaissance cell. Circ Res. 2009;105:1164-1176
    • (2009) Circ Res , vol.105 , pp. 1164-1176
    • Souders, C.A.1    Bowers, S.L.2    Baudino, T.A.3
  • 53
    • 0035379769 scopus 로고    scopus 로고
    • Induction and suppression of interferon-inducible protein 10 in reperfused myocardial infarcts may regulate angiogenesis
    • Frangogiannis NG, Mendoza LH, Lewallen M, et al. Induction and suppression of interferon-inducible protein 10 in reperfused myocardial infarcts may regulate angiogenesis. FASEB J. 2001;15:1428-1430
    • (2001) FASEB J. , vol.15 , pp. 1428-1430
    • Frangogiannis, N.G.1    Mendoza, L.H.2    Lewallen, M.3
  • 54
    • 72449132876 scopus 로고    scopus 로고
    • Induction of the CXC chemokine interferon-gamma-inducible protein 10 regulates the reparative response following myocardial infarction
    • Bujak M, Dobaczewski M, Gonzalez-Quesada C, et al. Induction of the CXC chemokine interferon-gamma-inducible protein 10 regulates the reparative response following myocardial infarction. Circ Res. 2009; 105:973-983
    • (2009) Circ Res , vol.105 , pp. 973-983
    • Bujak, M.1    Dobaczewski, M.2    Gonzalez-Quesada, C.3
  • 55
    • 0032722467 scopus 로고    scopus 로고
    • Granulocyte apoptosis and its role in the resolution and control of lung inflammation
    • Haslett C. Granulocyte apoptosis and its role in the resolution and control of lung inflammation. Am J Respir Crit Care Med. 1999;160(5 pt 2): S5-S11
    • (1999) Am J Respir Crit Care Med , vol.160 , Issue.5 PART 2
    • Haslett, C.1
  • 56
    • 0036884424 scopus 로고    scopus 로고
    • A blast from the past: Clearance of apoptotic cells regulates immune responses
    • Savill J, Dransfield I, Gregory C, et al. A blast from the past: Clearance of apoptotic cells regulates immune responses. Nat Rev Immunol. 2002;2: 965-975
    • (2002) Nat Rev Immunol , vol.2 , pp. 965-975
    • Savill, J.1    Dransfield, I.2    Gregory, C.3
  • 57
    • 2342428467 scopus 로고    scopus 로고
    • Hyaluronan fragments stimulate endothelial recognition of injury through TLR4
    • Taylor KR, Trowbridge JM, Rudisill JA, et al. Hyaluronan fragments stimulate endothelial recognition of injury through TLR4. J Biol Chem. 2004;279:17079-17084
    • (2004) J Biol Chem , vol.279 , pp. 17079-17084
    • Taylor, K.R.1    Trowbridge, J.M.2    Rudisill, J.A.3
  • 58
  • 59
    • 0036143406 scopus 로고    scopus 로고
    • Morphological characteristics of the microvasculature in healing myocardial infarcts
    • Ren G, Michael LH, Entman ML, et al. Morphological characteristics of the microvasculature in healing myocardial infarcts. J Histochem Cytochem. 2002;50:71-79
    • (2002) J Histochem Cytochem , vol.50 , pp. 71-79
    • Ren, G.1    Michael, L.H.2    Entman, M.L.3
  • 60
    • 3242796605 scopus 로고    scopus 로고
    • Vascular mural cells in healing canine myocardial infarcts
    • Dobaczewski M, Akrivakis S, Nasser K, et al. Vascular mural cells in healing canine myocardial infarcts. J Histochem Cytochem. 2004;52: 1019-1029
    • (2004) J Histochem Cytochem , vol.52 , pp. 1019-1029
    • Dobaczewski, M.1    Akrivakis, S.2    Nasser, K.3
  • 61
    • 33845220020 scopus 로고    scopus 로고
    • The role of platelet-derived growth factor signaling in healing myocardial infarcts
    • Zymek P, Bujak M, Chatila K, et al. The role of platelet-derived growth factor signaling in healing myocardial infarcts. J Am Coll Cardiol. 2006; 48:2315-2323
    • (2006) J Am Coll Cardiol , vol.48 , pp. 2315-2323
    • Zymek, P.1    Bujak, M.2    Chatila, K.3
  • 62
    • 0034284216 scopus 로고    scopus 로고
    • IL-10 is induced in the reperfused myocardium and may modulate the reaction to injury
    • Frangogiannis NG, Mendoza LH, Lindsey ML, et al. IL-10 is induced in the reperfused myocardium and may modulate the reaction to injury. J Immunol. 2000;165:2798-2808
    • (2000) J Immunol , vol.165 , pp. 2798-2808
    • Frangogiannis, N.G.1    Mendoza, L.H.2    Lindsey, M.L.3
  • 63
    • 0034048281 scopus 로고    scopus 로고
    • Crucial role of endogenous interleukin-10 production in myocardial ischemia/reperfusion injury
    • Yang Z, Zingarelli B, Szabo C. Crucial role of endogenous interleukin-10 production in myocardial ischemia/reperfusion injury. Circulation. 2000; 101:1019-1026
    • (2000) Circulation , vol.101 , pp. 1019-1026
    • Yang, Z.1    Zingarelli, B.2    Szabo, C.3
  • 64
    • 34047123693 scopus 로고    scopus 로고
    • Interleukin-10 is not a critical regulator of infarct healing and left ventricular remodeling
    • Zymek P, Nah DY, Bujak M, et al. Interleukin-10 is not a critical regulator of infarct healing and left ventricular remodeling. Cardiovasc Res. 2007;74:313-322
    • (2007) Cardiovasc Res , vol.74 , pp. 313-322
    • Zymek, P.1    Nah, D.Y.2    Bujak, M.3
  • 65
    • 34047148354 scopus 로고    scopus 로고
    • The role of TGF-beta signaling in myocardial infarction and cardiac remodeling
    • Bujak M, Frangogiannis NG. The role of TGF-beta signaling in myocardial infarction and cardiac remodeling. Cardiovasc Res. 2007;74:184-195
    • (2007) Cardiovasc Res , vol.74 , pp. 184-195
    • Bujak, M.1    Frangogiannis, N.G.2
  • 66
    • 0023834148 scopus 로고
    • Transforming growth factor beta regulates the expression and structure of extracellular matrix chondroitin/dermatan sulfate proteoglycans
    • Bassols A, Massague J. Transforming growth factor beta regulates the expression and structure of extracellular matrix chondroitin/dermatan sulfate proteoglycans. J Biol Chem. 1988;263:3039-3045
    • (1988) J Biol Chem , vol.263 , pp. 3039-3045
    • Bassols, A.1    Massague, J.2
  • 67
    • 0022976357 scopus 로고
    • Enhanced production and extracellular deposition of the endothelial-type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-beta
    • Laiho M, Saksela O, Andreasen PA, et al. Enhanced production and extracellular deposition of the endothelial-type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-beta. J Cell Biol. 1986;103(6 pt 1):2403-2410
    • (1986) J Cell Biol , vol.103 , Issue.6 PART 1 , pp. 2403-2410
    • Laiho, M.1    Saksela, O.2    Andreasen, P.A.3
  • 68
    • 8644268825 scopus 로고    scopus 로고
    • Inhibition of TGF-beta signaling exacerbates early cardiac dysfunction but prevents late remodeling after infarction
    • Ikeuchi M, Tsutsui H, Shiomi T, et al. Inhibition of TGF-beta signaling exacerbates early cardiac dysfunction but prevents late remodeling after infarction. Cardiovasc Res. 2004;64:526-535
    • (2004) Cardiovasc Res , vol.64 , pp. 526-535
    • Ikeuchi, M.1    Tsutsui, H.2    Shiomi, T.3
  • 69
    • 21044435626 scopus 로고    scopus 로고
    • Postinfarction gene therapy against transforming growth factor-beta signal modulates infarct tissue dynamics and attenuates left ventricular remodeling and heart failure
    • Okada H, Takemura G, Kosai K, et al. Postinfarction gene therapy against transforming growth factor-beta signal modulates infarct tissue dynamics and attenuates left ventricular remodeling and heart failure. Circulation. 2005;111:2430-2437
    • (2005) Circulation , vol.111 , pp. 2430-2437
    • Okada, H.1    Takemura, G.2    Kosai, K.3
  • 70
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi Y, Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell. 2003;113:685-700
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 71
    • 35848951385 scopus 로고    scopus 로고
    • Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling
    • Bujak M, Ren G, Kweon HJ, et al. Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling. Circulation. 2007; 116:2127-2138
    • (2007) Circulation , vol.116 , pp. 2127-2138
    • Bujak, M.1    Ren, G.2    Kweon, H.J.3
  • 72
    • 77956627158 scopus 로고    scopus 로고
    • Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction
    • Dobaczewski M, Bujak M, Li N, et al. Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction. Circ Res. 2010;107:418-428
    • (2010) Circ Res , vol.107 , pp. 418-428
    • Dobaczewski, M.1    Bujak, M.2    Li, N.3
  • 73
    • 79955703474 scopus 로고    scopus 로고
    • GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice
    • Kempf T, Zarbock A, Widera C, et al. GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice. Nat Med. 2011;17:581-588
    • (2011) Nat Med , vol.17 , pp. 581-588
    • Kempf, T.1    Zarbock, A.2    Widera, C.3
  • 74
    • 0034919056 scopus 로고    scopus 로고
    • Decoy receptors: A strategy to regulate inflammatory cytokines and chemokines
    • Mantovani A, Locati M, Vecchi A, et al. Decoy receptors: A strategy to regulate inflammatory cytokines and chemokines. Trends Immunol. 2001;22:328-336
    • (2001) Trends Immunol , vol.22 , pp. 328-336
    • Mantovani, A.1    Locati, M.2    Vecchi, A.3
  • 75
    • 84865498877 scopus 로고    scopus 로고
    • The chemokine decoy receptor D6 prevents excessive inflammation and adverse ventricular remodeling after myocardial infarction
    • Cochain C, Auvynet C, Poupel L, et al. The chemokine decoy receptor D6 prevents excessive inflammation and adverse ventricular remodeling after myocardial infarction. Arterioscler Thromb Vasc Biol. 2012;32: 2206-2213
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 2206-2213
    • Cochain, C.1    Auvynet, C.2    Poupel, L.3
  • 76
    • 84865298775 scopus 로고    scopus 로고
    • Dissecting negative regulation of Toll-like receptor signaling
    • Kondo T, Kawai T, Akira S. Dissecting negative regulation of Toll-like receptor signaling. Trends Immunol. 2012;33:449-458
    • (2012) Trends Immunol , vol.33 , pp. 449-458
    • Kondo, T.1    Kawai, T.2    Akira, S.3
  • 77
    • 84871914561 scopus 로고    scopus 로고
    • Endogenous IRAK-M attenuates postinfarction remodeling through effects on macrophages and fibroblasts
    • Chen W, Saxena A, Li N, et al. Endogenous IRAK-M attenuates postinfarction remodeling through effects on macrophages and fibroblasts. Arterioscler Thromb Vasc Biol. 2012;32:2598-2608
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 2598-2608
    • Chen, W.1    Saxena, A.2    Li, N.3
  • 78
    • 84878183269 scopus 로고    scopus 로고
    • The extracellular matrix modulates fibroblast phenotype and function in the infarcted myocardium
    • Dobaczewski M, de Haan JJ, Frangogiannis NG. The extracellular matrix modulates fibroblast phenotype and function in the infarcted myocardium. J Cardiovasc Transl Res. 2012;5:837-847
    • (2012) J Cardiovasc Transl Res , vol.5 , pp. 837-847
    • Dobaczewski, M.1    De Haan, J.J.2    Frangogiannis, N.G.3
  • 79
    • 84860145209 scopus 로고    scopus 로고
    • Matricellular proteins in cardiac adaptation and disease
    • Frangogiannis NG. Matricellular proteins in cardiac adaptation and disease. Physiol Rev. 2012;92:635-688
    • (2012) Physiol Rev , vol.92 , pp. 635-688
    • Frangogiannis, N.G.1
  • 80
    • 20444489650 scopus 로고    scopus 로고
    • The critical role of endogenous thrombospondin (TSP)-1 in preventing expansion of healing myocardial infarcts
    • Frangogiannis NG, Ren G, Dewald O, et al. The critical role of endogenous thrombospondin (TSP)-1 in preventing expansion of healing myocardial infarcts. Circulation. 2005;111:2935-2942
    • (2005) Circulation , vol.111 , pp. 2935-2942
    • Frangogiannis, N.G.1    Ren, G.2    Dewald, O.3
  • 81
    • 60549088560 scopus 로고    scopus 로고
    • Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction
    • Schellings MW, Vanhoutte D, Swinnen M, et al. Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction. J Exp Med. 2009;206:113-123
    • (2009) J Exp Med , vol.206 , pp. 113-123
    • Schellings, M.W.1    Vanhoutte, D.2    Swinnen, M.3
  • 82
    • 0017289098 scopus 로고
    • Deleterious effects of methylprednisolone in patients with myocardial infarction
    • Roberts R, DeMello V, Sobel BE. Deleterious effects of methylprednisolone in patients with myocardial infarction. Circulation. 1976;53(suppl 3):I204-I206
    • (1976) Circulation , vol.53 , Issue.SUPPL. 3
    • Roberts, R.1    Demello, V.2    Sobel, B.E.3
  • 83
    • 0023847806 scopus 로고
    • Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti- Mo1, anti-CD11b) that inhibits leukocyte adhesion
    • Simpson PJ, Todd RF III, Fantone JC, et al. Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti- Mo1, anti-CD11b) that inhibits leukocyte adhesion. J Clin Invest. 1988;81:624-629
    • (1988) J Clin Invest , vol.81 , pp. 624-629
    • Simpson, P.J.1    Todd III, R.F.2    Fantone, J.C.3
  • 84
    • 0035808003 scopus 로고    scopus 로고
    • Double-blind, randomized trial of an anti-CD18 antibody in conjunction with recombinant tissue plasminogen activator for acute myocardial infarction: Limitation of myocardial infarction following thrombolysis in acute myocardial infarction( limit AMI) study
    • Baran KW, Nguyen M, McKendall GR, et al. Double-blind, randomized trial of an anti-CD18 antibody in conjunction with recombinant tissue plasminogen activator for acute myocardial infarction: Limitation of myocardial infarction following thrombolysis in acute myocardial infarction( LIMIT AMI) study. Circulation. 2001;104:2778-2783
    • (2001) Circulation , vol.104 , pp. 2778-2783
    • Baran, K.W.1    Nguyen, M.2    McKendall, G.R.3
  • 85
    • 41149107026 scopus 로고    scopus 로고
    • Aging-related defects are associated with adverse cardiac remodeling in a mouse model of reperfused myocardial infarction
    • Bujak M, Kweon HJ, Chatila K, et al. Aging-related defects are associated with adverse cardiac remodeling in a mouse model of reperfused myocardial infarction. J Am Coll Cardiol. 2008;51:1384-1392
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1384-1392
    • Bujak, M.1    Kweon, H.J.2    Chatila, K.3
  • 86
    • 77951665667 scopus 로고    scopus 로고
    • Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction [virginia commonwealth university anakinra remodeling trial( vcu-art) pilot study
    • e1371
    • Abbate A, Kontos MC, Grizzard JD, et al. Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction [Virginia Commonwealth University Anakinra Remodeling Trial( VCU-ART) Pilot study]. Am J Cardiol. 2010;105:1371-1377 e1371
    • (2010) Am J Cardiol , vol.105 , pp. 1371-1377
    • Abbate, A.1    Kontos, M.C.2    Grizzard, J.D.3
  • 87
    • 84876981024 scopus 로고    scopus 로고
    • Effects of interleukin- 1 blockade with anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCU-ART2) pilot study
    • Abbate A, Van Tassell BW, Biondi-Zoccai G, et al. Effects of interleukin- 1 blockade with anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCU-ART2) pilot study]. Am J Cardiol. 2013;111:1394-1400
    • (2013) Am J Cardiol , vol.111 , pp. 1394-1400
    • Abbate, A.1    Van Tassell, B.W.2    Biondi-Zoccai, G.3
  • 88
    • 4944259106 scopus 로고    scopus 로고
    • Left ventricular remodeling and heart failure in diabetic patients treated with primary angioplasty for acute myocardial infarction
    • Carrabba N, Valenti R, Parodi G, et al. Left ventricular remodeling and heart failure in diabetic patients treated with primary angioplasty for acute myocardial infarction. Circulation. 2004;110:1974-1979
    • (2004) Circulation , vol.110 , pp. 1974-1979
    • Carrabba, N.1    Valenti, R.2    Parodi, G.3
  • 89
    • 80052819014 scopus 로고    scopus 로고
    • Transforming growth factor( TGF)-beta signaling in cardiac remodeling
    • Dobaczewski M, Chen W, Frangogiannis NG. Transforming growth factor( TGF)-beta signaling in cardiac remodeling. J Mol Cell Cardiol. 2011;51:600-606
    • (2011) J Mol Cell Cardiol , vol.51 , pp. 600-606
    • Dobaczewski, M.1    Chen, W.2    Frangogiannis, N.G.3
  • 90
    • 36148993519 scopus 로고    scopus 로고
    • Serial measurement of monocyte chemoattractant protein-1 after acute coronary syndromes: Results from the A to Z trial
    • de Lemos JA, Morrow DA, Blazing MA, et al. Serial measurement of monocyte chemoattractant protein-1 after acute coronary syndromes: Results from the A to Z trial. J Am Coll Cardiol. 2007;50:2117-2124
    • (2007) J Am Coll Cardiol , vol.50 , pp. 2117-2124
    • De Lemos, J.A.1    Morrow, D.A.2    Blazing, M.A.3
  • 91
    • 77950940268 scopus 로고    scopus 로고
    • Circulating biomarkers of collagen metabolism in cardiac diseases
    • Lopez B, Gonzalez A, Diez J. Circulating biomarkers of collagen metabolism in cardiac diseases. Circulation. 2010;121:1645-1654
    • (2010) Circulation , vol.121 , pp. 1645-1654
    • Lopez, B.1    Gonzalez, A.2    Diez, J.3
  • 92
    • 84858419467 scopus 로고    scopus 로고
    • Biomarkers: Hopes and challenges in the path from discovery to clinical practice
    • Frangogiannis NG. Biomarkers: Hopes and challenges in the path from discovery to clinical practice. Transl Res. 2012;159:197-204
    • (2012) Transl Res , vol.159 , pp. 197-204
    • Frangogiannis, N.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.