Acute and long-term effects of arsenite in HepG2 cells: Modulation of insulin signaling

BioMetals

Volumn 27, Issue 2, 2014, Pages 317-332

  Hamann, Ingrit ^a   Petroll, Kerstin ^a   Hou, Xiaoqing ^a   Anwar Mohamed, Anwar ^a   El Kadi, Ayman O S ^a   Klotz, Lars Oliver ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Akt; Arsenic; FoxO transcription factors; HepG2 cells; Insulin signaling; Selenium homeostasis

Indexed keywords

ARSENIC TRIOXIDE; DNA; GLUCOSE 6 PHOSPHATASE; INSULIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SELENOPROTEIN P; SERINE; TRANSCRIPTION FACTOR FOXO; WORTMANNIN; ANDROSTANE DERIVATIVE; ARSENOUS ACID DERIVATIVE; PADGEM PROTEIN; SELP PROTEIN, HUMAN;

ARTICLE; CELL METABOLISM; CELL STIMULATION; CELL STRAIN HEPG2; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE RELEASE; DNA BINDING; DOWN REGULATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE EXPRESSION; GENE TARGETING; GLUCOSE METABOLISM; HEPATOMA CELL; HUMAN; HUMAN CELL; INSULIN SENSITIVITY; INTRACELLULAR SIGNALING; LONG TERM EXPOSURE; PROTEIN PHOSPHORYLATION; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; HEPG2 CELL LINE; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANDROSTADIENES; ARSENITES; HEP G2 CELLS; HUMANS; INSULIN; P-SELECTIN; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84896317760     PISSN: 09660844     EISSN: 15728773     Source Type: Journal    
DOI: 10.1007/s10534-014-9714-y     Document Type: Article

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