High selenium intake and increased diabetes risk: Experimental evidence for interplay between selenium and carbohydrate metabolism

Journal of Clinical Biochemistry and Nutrition

Volumn 48, Issue 1, 2011, Pages 40-45

  Steinbrenner, Holger ^a   Speckmann, Bodo ^a   Pinto, Antonio ^a   Sies, Helmut ^a,b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Akt; Glutathione peroxidase; Hyperglycemia; Insulin; PGC 1 ; Selenoprotein

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CADMIUM; CARBOHYDRATE; COPPER; DEXAMETHASONE; GLUCAGON; GLUCOCORTICOID; GLUTATHIONE PEROXIDASE 1; INSULIN; INSULIN RECEPTOR; METFORMIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SELENATE; SELENITE; SELENIUM; SELENIUM DERIVATIVE; SELENOPROTEIN P; SODIUM SELENITE; STREPTOZOCIN; VANADIUM; VANADYL SULFATE; ZINC;

APOPTOSIS; CARBOHYDRATE METABOLISM; CELL PROTECTION; CROSS LINKING; DIABETES MELLITUS; DIET SUPPLEMENTATION; DIETARY INTAKE; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG MEGADOSE; DRUG METABOLISM; GENE OVEREXPRESSION; GLUCONEOGENESIS; GLUCOSE HOMEOSTASIS; HOMEOSTASIS; HUMAN; HYPERGLYCEMIA; HYPERINSULINEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; INSULIN RESISTANCE; LIVER; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATION REDUCTION STATE; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RECEPTOR UPREGULATION; REGULATORY MECHANISM; REVIEW; RISK FACTOR; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES;

ANIMALIA; MUS;

EID: 78650748209     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.11-002FR     Document Type: Review

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