Resveratrol attenuates NF-κB-binding activity but not cytokine production in mechanically ventilated mice

Acta Anaesthesiologica Scandinavica

Volumn 58, Issue 4, 2014, Pages 487-494

  Van Der Wal, S E I ^a   Vaneker, M ^a   Kox, M ^a   Braak, G ^b   Van Hees, H W H ^a   Van Den Brink, I A ^a   Van De Pol, F M ^a   Heunks, L M ^a   Van Der Hoeven, J G ^a   Joosten, L A B ^a   Vissers, K C P ^a   Scheffer, G J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b BERNHOVEN HOSPITAL   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; RESVERATROL; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; CARDIOPULMONARY FUNCTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DNA BINDING; LUNG HOMOGENATE; MALE; MOUSE; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; TIDAL VOLUME;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYTOKINES; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEART; LUNG; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B; RESPIRATION, ARTIFICIAL; STILBENES;

EID: 84896297721     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/aas.12276     Document Type: Article

References (36)

1. Gajic O, Dara SI, Mendez JL, Adesanya AO, Festic E, Caples SM, Rana R, St Sauver JL, Lymp JF, Afessa B, Hubmayr RD,. Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation. Crit Care Med 2004; 32: 1817-1824.
2. Ranieri VM, Giunta F, Suter PM, Slutsky AS,. Mechanical ventilation as a mediator of multisystem organ failure in acute respiratory distress syndrome. JAMA 2000; 284: 43-44.
3. Wolthuis EK, Choi G, Dessing MC, Bresser P, Lutter R, Dzoljic M, van der Poll T, Vroom MB, Hollmann M, Schultz MJ,. Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents pulmonary inflammation in patients without preexisting lung injury. Anesthesiology 2008; 108: 46-54.
4. Vaneker M, Halbertsma FJ, van Egmond J, Netea MG, Dijkman HB, Snijdelaar DG, Joosten LA, van der Hoeven JG, Scheffer GJ,. Mechanical ventilation in healthy mice induces reversible pulmonary and systemic cytokine elevation with preserved alveolar integrity: an in vivo model using clinical relevant ventilation settings. Anesthesiology 2007; 107: 419-426.
5. Dolinay T, Kim YS, Howrylak J, Hunninghake GM, An CH, Fredenburgh L, Massaro AF, Rogers A, Gazourian L, Nakahira K, Haspel JA, Landazury R, Eppanapally S, Christie JD, Meyer NJ, Ware LB, Christiani DC, Ryter SW, Baron RM, Choi AM,. Inflammasome-regulated cytokines are critical mediators of acute lung injury. Am J Respir Crit Care Med 2012; 185: 1225-1234.
6. Matzinger P,. The danger model: a renewed sense of self. Science 2002; 296: 301-305.
7. Abraham E,. Neutrophils and acute lung injury. Crit Care Med 2003; 31: S195-199.
8. Kawai T, Akira S,. TLR signaling. Semin Immunol 2007; 19: 24-32.
9. Trinchieri G, Sher A,. Cooperation of Toll-like receptor signals in innate immune defence. Nat Rev Immunol 2007; 7: 179-190.
10. Beutler B,. Toll-like receptors and their place in immunology. Where does the immune response to infection begin? Nat Rev Immunol 2004; 4: 498.
11. Imai Y, Kuba K, Neely GG, Yaghubian-Malhami R, Perkmann T, van Loo G, Ermolaeva M, Veldhuizen R, Leung YH, Wang H, Liu H, Sun Y, Pasparakis M, Kopf M, Mech C, Bavari S, Peiris JS, Slutsky AS, Akira S, Hultqvist M, Holmdahl R, Nicholls J, Jiang C, Binder CJ, Penninger JM,. Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell 2008; 133: 235-249.
12. Vaneker M, Joosten LA, Heunks LM, Snijdelaar DG, Halbertsma FJ, van Egmond J, Netea MG, van der Hoeven JG, Scheffer GJ,. Low-tidal-volume mechanical ventilation induces a toll-like receptor 4-dependent inflammatory response in healthy mice. Anesthesiology 2008; 109: 465-472.
13. Kenny EF, O'Neill LA,. Signalling adaptors used by Toll-like receptors: an update. Cytokine 2008; 43: 342-349.
14. Sebai H, Ristorcelli E, Sbarra V, Hovsepian S, Fayet G, Aouani E, Lombardo D,. Protective effect of resveratrol against LPS-induced extracellular lipoperoxidation in AR42J cells partly via a Myd88-dependent signaling pathway. Arch Biochem Biophys 2010; 495: 56-61.
15. Jeong E, Lee JY,. Intrinsic and extrinsic regulation of innate immune receptors. Yonsei Med J 2011; 52: 379-392.
16. Haddad JJ, Abdel-Karim NE,. NF-kappaB cellular and molecular regulatory mechanisms and pathways: therapeutic pattern or pseudoregulation? Cell Immunol 2011; 271: 5-14.
17. Vaneker M, Heunks LM, Joosten LA, van Hees HW, Snijdelaar DG, Halbertsma FJ, van Egmond J, Netea MG, van der Hoeven JG, Scheffer GJ,. Mechanical ventilation induces a Toll/interleukin-1 receptor domain-containing adapter-inducing interferon beta-dependent inflammatory response in healthy mice. Anesthesiology 2009; 111: 836-843.
18. Rahman A, Fazal F,. Blocking NF-kappaB: an inflammatory issue. Proc Am Thorac Soc 2011; 8: 497-503.
19. Youn HS, Lee JY, Fitzgerald KA, Young HA, Akira S, Hwang DH,. Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex. J Immunol 2005; 175: 3339-3346.
20. Kundu JK, Shin YK, Kim SH, Surh YJ,. Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kappaB in mouse skin by blocking IkappaB kinase activity. Carcinogenesis 2006; 27: 1465-1474.
21. Cao Q, Jing C, Tang X, Yin Y, Han X, Wu W,. Protective effect of resveratrol on acute lung injury induced by lipopolysaccharide in mice. Anat Rec (Hoboken) 2011; 294: 527-532.
22. Gupta SC, Kim JH, Kannappan R, Reuter S, Dougherty PM, Aggarwal BB,. Role of nuclear factor kappaB-mediated inflammatory pathways in cancer-related symptoms and their regulation by nutritional agents. Exp Biol Med (Maywood) 2011; 236: 658-671.
23. Lei M, Wang JG, Xiao DM, Fan M, Wang DP, Xiong JY, Chen Y, Ding Y, Liu SL,. Resveratrol inhibits interleukin 1beta-mediated inducible nitric oxide synthase expression in articular chondrocytes by activating SIRT1 and thereby suppressing nuclear factor-kappaB activity. Eur J Pharmacol 2012; 674: 73-79.
24. Wyke SM, Russell ST, Tisdale MJ,. Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation. Br J Cancer 2004; 91: 1742-1750.
25. Holmes-McNary M, Baldwin AS Jr., Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkappaB kinase. Cancer Res 2000; 60: 3477-3483.
26. Kim MH, Yoo DS, Lee SY, Byeon SE, Lee YG, Min T, Rho HS, Rhee MH, Lee J, Cho JY,. The TRIF/TBK1/IRF-3 activation pathway is the primary inhibitory target of resveratrol, contributing to its broad-spectrum anti-inflammatory effects. Pharmazie 2011; 66: 293-300.
27. Janssen BJ, Smits JF,. Autonomic control of blood pressure in mice: basic physiology and effects of genetic modification. Am J Physiol Regul Integr Comp Physiol 2002; 282: R1545-1564.
28. Li LF, Ouyang B, Choukroun G, Matyal R, Mascarenhas M, Jafari B, Bonventre JV, Force T, Quinn DA,. Stretch-induced IL-8 depends on c-Jun NH2-terminal and nuclear factor-kappaB-inducing kinases. Am J Physiol Lung Cell Mol Physiol 2003; 285: L464-475.
29. Li J, Wang S, Xu J, Dai Q, Xu S, Sun H, Peng L,. [Regulation trend of resveratrol on TNF-alpha, IL-1beta, IL-6 expressions in bronchoalveolar lavage fluid of RSV-infected BALB/c mice]. Zhongguo Zhong Yao Za Zhi 2012; 37: 1451-1454.
30. Kirchner EA, Mols G, Hermle G, Muehlschlegel JD, Geiger KK, Guttmann J, Pahl HL,. Reduced activation of immunomodulatory transcription factors during positive end-expiratory pressure adjustment based on volume-dependent compliance in isolated perfused rabbit lungs. Br J Anaesth 2005; 94: 530-535.
31. Brown J, Wang H, Hajishengallis GN, Martin M,. TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk. J Dent Res 2011; 90: 417-427.
32. McCall MD, Pawlick R, Shapiro AM,. Resveratrol fails to improve marginal mass engraftment of transplanted islets of Langerhans in mice. Islets 2011; 3: 241-245.
33. Singh NP, Singh UP, Hegde VL, Guan H, Hofseth L, Nagarkatti M, Nagarkatti PS,. Resveratrol (trans-3,5,4'-trihydroxystilbene) suppresses EL4 tumor growth by induction of apoptosis involving reciprocal regulation of SIRT1 and NF-kappaB. Mol Nutr Food Res 2011; 55: 1207-1218.
34. Lee M, Kim S, Kwon OK, Oh SR, Lee HK, Ahn K,. Anti-inflammatory and anti-asthmatic effects of resveratrol, a polyphenolic stilbene, in a mouse model of allergic asthma. Int Immunopharmacol 2009; 9: 418-424.
35. Sharma S, Kulkarni SK, Chopra K,. Effect of resveratrol, a polyphenolic phytoalexin, on thermal hyperalgesia in a mouse model of diabetic neuropathic pain. Fundam Clin Pharmacol 2007; 21: 89-94.
36. Svajger U, Jeras M,. Anti-inflammatory effects of resveratrol and its potential use in therapy of immune-mediated diseases. Int Rev Immunol 2012; 31: 202-222.