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Volumn 15, Issue 1, 2014, Pages 45-53

The physiological roles of apolipoprotein J/clusterin in metabolic and cardiovascular diseases

Author keywords

Atherosclerosis; Clusterin deficient mice; Diabetes; High density cholesterol; Oxidative stress

Indexed keywords

CHAPERONE; CLUSTERIN; HIGH DENSITY LIPOPROTEIN; ISOPROTEIN; NUCLEAR CLUSTERIN; SECRETED CLUSTERIN; UNCLASSIFIED DRUG;

EID: 84896290419     PISSN: 13899155     EISSN: 15732606     Source Type: Journal    
DOI: 10.1007/s11154-013-9275-3     Document Type: Article
Times cited : (113)

References (94)
  • 4
    • 79959919890 scopus 로고    scopus 로고
    • Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease
    • Besler C, Heinrich K, Rohrer L, Doerries C, Riwanto M, Shih DM, et al. Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease. J Clin Invest. 2011;121:2693-708.
    • (2011) J Clin Invest , vol.121 , pp. 2693-2708
    • Besler, C.1    Heinrich, K.2    Rohrer, L.3    Doerries, C.4    Riwanto, M.5    Shih, D.M.6
  • 7
    • 78649861855 scopus 로고    scopus 로고
    • HDL apolipoprotein-related peptides in the treatment of atherosclerosis and other inflammatory disorders
    • Getz GS, Wool GD, Reardon CA. HDL apolipoprotein-related peptides in the treatment of atherosclerosis and other inflammatory disorders. Curr Pharm Des. 2010;16:3173-84.
    • (2010) Curr Pharm des , vol.16 , pp. 3173-3184
    • Getz, G.S.1    Wool, G.D.2    Reardon, C.A.3
  • 8
    • 0035856544 scopus 로고    scopus 로고
    • High-density lipoprotein and the dynamics of atherosclerotic lesions
    • Navab M, Van Lenten BJ, Reddy ST, Fogelman AM. High-density lipoprotein and the dynamics of atherosclerotic lesions. Circulation. 2001;104:2386-7. (Pubitemid 33108367)
    • (2001) Circulation , vol.104 , Issue.20 , pp. 2386-2387
    • Navab, M.1    Van Lenten, B.J.2    Reddy, S.T.3    Fogelman, A.M.4
  • 9
    • 42949118926 scopus 로고    scopus 로고
    • An apolipoprotein A-I mimetic dose-dependently increases the formation of prebeta1 HDL in human plasma
    • Troutt JS, Alborn WE, Mosior MK, Dai J, Murphy AT, Beyer TP, et al. An apolipoprotein A-I mimetic dose-dependently increases the formation of prebeta1 HDL in human plasma. J Lipid Res. 2008;49:581-7.
    • (2008) J Lipid Res , vol.49 , pp. 581-587
    • Troutt, J.S.1    Alborn, W.E.2    Mosior, M.K.3    Dai, J.4    Murphy, A.T.5    Beyer, T.P.6
  • 11
    • 78650070687 scopus 로고    scopus 로고
    • Apolipoprotein A-I mimetic peptides prevent atherosclerosis development and reduce plaque inflammation in a murine model of diabetes
    • Morgantini C, Imaizumi S, Grijalva V, Navab M, Fogelman AM, Reddy ST. Apolipoprotein A-I mimetic peptides prevent atherosclerosis development and reduce plaque inflammation in a murine model of diabetes. Diabetes. 2010;59:3223-8.
    • (2010) Diabetes , vol.59 , pp. 3223-3228
    • Morgantini, C.1    Imaizumi, S.2    Grijalva, V.3    Navab, M.4    Fogelman, A.M.5    Reddy, S.T.6
  • 12
    • 80053431876 scopus 로고    scopus 로고
    • Anti-inflammatory and antioxidant properties of HDLs are impaired in type 2 diabetes
    • Morgantini C, Natali A, Boldrini B, Imaizumi S, Navab M, Fogelman AM, et al. Anti-inflammatory and antioxidant properties of HDLs are impaired in type 2 diabetes. Diabetes. 2011;60:2617-23.
    • (2011) Diabetes , vol.60 , pp. 2617-2623
    • Morgantini, C.1    Natali, A.2    Boldrini, B.3    Imaizumi, S.4    Navab, M.5    Fogelman, A.M.6
  • 13
    • 84874469648 scopus 로고    scopus 로고
    • Altered activation of endothelial anti- and proapoptotic pathways by high-density lipoprotein from patients with coronary artery disease: Role of high-density lipoprotein-proteome remodeling
    • Riwanto M, Rohrer L, Roschitzki B, Besler C, Mocharla P, Mueller M, et al. Altered activation of endothelial anti- and proapoptotic pathways by high-density lipoprotein from patients with coronary artery disease: role of high-density lipoprotein-proteome remodeling. Circulation. 2013;127:891-904.
    • (2013) Circulation , vol.127 , pp. 891-904
    • Riwanto, M.1    Rohrer, L.2    Roschitzki, B.3    Besler, C.4    Mocharla, P.5    Mueller, M.6
  • 14
    • 0034719136 scopus 로고    scopus 로고
    • Clusterin is an ATP - Independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent state
    • DOI 10.1021/bi002189x
    • Poon S, Easterbrook-Smith SB, Rybchyn MS, Carver JA, Wilson MR. Clusterin is an ATP-independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent state. Biochemistry. 2000;39:15953-60. (Pubitemid 32038257)
    • (2000) Biochemistry , vol.39 , Issue.51 , pp. 15953-15960
    • Poon, S.1    Easterbrook-Smith, S.B.2    Rybchyn, M.S.3    Carver, J.A.4    Wilson, M.R.5
  • 16
    • 0028211892 scopus 로고
    • Molecular characterization of human TRPM-2/clusterin, a gene associated with sperm maturation, apoptosis and neurodegeneration
    • Wong P, Taillefer D, Lakins J, Pineault J, Chader G, Tenniswood M. Molecular characterization of human TRPM-2/clusterin, a gene associated with sperm maturation, apoptosis and neurodegeneration. Eur J Biochem. 1994;221:917-25. (Pubitemid 24146191)
    • (1994) European Journal of Biochemistry , vol.221 , Issue.3 , pp. 917-925
    • Wong, P.1    Taillefer, D.2    Lakins, J.3    Pineault, J.4    Chader, G.5    Tenniswood, M.6
  • 20
    • 78549264026 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
    • Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, et al. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. NatGenet. 2009;41:1094-9.
    • (2009) NatGenet , vol.41 , pp. 1094-1099
    • Lambert, J.C.1    Heath, S.2    Even, G.3    Campion, D.4    Sleegers, K.5    Hiltunen, M.6
  • 21
    • 70349558522 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
    • Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet. 2009;41:1088-93.
    • (2009) Nat Genet , vol.41 , pp. 1088-1093
    • Harold, D.1    Abraham, R.2    Hollingworth, P.3    Sims, R.4    Gerrish, A.5    Hamshere, M.L.6
  • 22
  • 23
    • 0006475111 scopus 로고
    • Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: Identity to sulfated glycoprotein 2, a constituent of rat testis fluid
    • Jenne DE, Tschopp J. Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid. Proc Natl Acad Sci U S A. 1989;86:7123-7. (Pubitemid 19240877)
    • (1989) Proceedings of the National Academy of Sciences of the United States of America , vol.86 , Issue.18 , pp. 7123-7127
    • Jenne, D.E.1    Tschopp, J.2
  • 24
    • 33750694197 scopus 로고    scopus 로고
    • Regulation of clusterin/apolipoprotein J, a functional homologue to the small heat shock proteins, by oxidative stress in ageing and age-related diseases
    • DOI 10.1080/10715760600902310, PII WNK7T55278T7PP8P, Free Radicals in the Aging Process - The 'Free Radical Theory of Aging' 50 years after -
    • Trougakos IP, Gonos ES. Regulation of clusterin/apolipoprotein J, a functional homologue to the small heat shock proteins, by oxidative stress in ageing and age-related diseases. Free Radic Res. 2006;40:1324-34. (Pubitemid 44698281)
    • (2006) Free Radical Research , vol.40 , Issue.12 , pp. 1324-1334
    • Trougakos, I.P.1    Gonos, E.S.2
  • 25
    • 81155154326 scopus 로고    scopus 로고
    • CRM1 protein-mediated regulation of nuclear clusterin (nCLU), an ionizing radiation-stimulated, Bax-dependent pro-death factor
    • Leskov KS, Araki S, Lavik JP, Gomez JA, Gama V, Gonos ES, et al. CRM1 protein-mediated regulation of nuclear clusterin (nCLU), an ionizing radiation-stimulated, Bax-dependent pro-death factor. J Biol Chem. 2011;286:40083-90.
    • (2011) J Biol Chem , vol.286 , pp. 40083-40090
    • Leskov, K.S.1    Araki, S.2    Lavik, J.P.3    Gomez, J.A.4    Gama, V.5    Gonos, E.S.6
  • 26
    • 34247387196 scopus 로고    scopus 로고
    • Stress-induced retrotranslocation of clusterin/ApoJ into the cytosol
    • DOI 10.1111/j.1600-0854.2007.00549.x
    • Nizard P, Tetley S, Le Drean Y, Watrin T, Le Goff P, Wilson MR, et al. Stress-induced retrotranslocation of clusterin/ApoJ into the cytosol. Traffic. 2007;8:554-65. (Pubitemid 46638565)
    • (2007) Traffic , vol.8 , Issue.5 , pp. 554-565
    • Nizard, P.1    Tetley, S.2    Le, D.Y.3    Watrin, T.4    Le, G.P.5    Wilson, M.R.6    Michel, D.7
  • 27
    • 0020601062 scopus 로고
    • Purification and characterization of a cell-aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid
    • Blaschuk O, Burdzy K, Fritz IB. Purification and characterization of a cell-aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid. J Biol Chem. 1983;258:7714-20. (Pubitemid 13038010)
    • (1983) Journal of Biological Chemistry , vol.258 , Issue.12 , pp. 7714-7720
    • Blaschuk, O.1    Burdzy, K.2    Fritz, I.B.3
  • 28
    • 0034161616 scopus 로고    scopus 로고
    • Clusterin is a secreted mammalian chaperone
    • DOI 10.1016/S0968-0004(99)01534-0, PII S0968000499015340
    • Wilson MR, Easterbrook-Smith SB. Clusterin is a secreted mammalian chaperone. Trends Biochem Sci. 2000;25:95-8. (Pubitemid 30122416)
    • (2000) Trends in Biochemical Sciences , vol.25 , Issue.3 , pp. 95-98
    • Wilson, M.R.1    Easterbrook-Smith, S.B.2
  • 29
    • 0028925349 scopus 로고
    • The expression of the avian clusterin gene can be driven by two alternative promoters with distinct regulatory elements
    • Michel D, Chatelain G, Herault Y, Brun G. The expression of the avian clusterin gene can be driven by two alternative promoters with distinct regulatory elements. Eur J Biochem. 1995;229:215-23.
    • (1995) Eur J Biochem , vol.229 , pp. 215-223
    • Michel, D.1    Chatelain, G.2    Herault, Y.3    Brun, G.4
  • 30
    • 0030660559 scopus 로고    scopus 로고
    • Effects of clusterin overexpression on TNFalpha- and TGFbeta-mediated death of L929 cells
    • DOI 10.1021/bi9703507
    • Humphreys D, Hochgrebe TT, Easterbrook-Smith SB, Tenniswood MP, Wilson MR. Effects of clusterin overexpression on TNFalphaand TGFbeta-mediated death of L929 cells. Biochemistry. 1997;36:15233-43. (Pubitemid 27527988)
    • (1997) Biochemistry , vol.36 , Issue.49 , pp. 15233-15243
    • Humphreys, D.1    Hochgrebe, T.T.2    Easterbrook-Smith, S.B.3    Tenniswood, M.P.4    Wilson, M.R.5
  • 31
    • 0028321386 scopus 로고
    • Clusterin expression in differentiating smooth muscle cells
    • Thomas-Salgar S, Millis AJ. Clusterin expression in differentiating smooth muscle cells. J Biol Chem. 1994;269:17879-85. (Pubitemid 24206177)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.27 , pp. 17879-17885
    • Thomas-Salgar, S.1    Millis, A.J.T.2
  • 32
    • 0028177321 scopus 로고
    • Transforming growth factor-beta 1 induces neuronal and astrocyte genes: Tubulin alpha 1, glial fibrillary acidic protein and clusterin
    • Laping NJ, Morgan TE, Nichols NR, Rozovsky I, Young-Chan CS, Zarow C, et al. Transforming growth factor-beta 1 induces neuronal and astrocyte genes: tubulin alpha 1, glial fibrillary acidic protein and clusterin. Neuroscience. 1994;58:563-72.
    • (1994) Neuroscience , vol.58 , pp. 563-572
    • Laping, N.J.1    Morgan, T.E.2    Nichols, N.R.3    Rozovsky, I.4    Young-Chan, C.S.5    Zarow, C.6
  • 33
    • 84880332207 scopus 로고    scopus 로고
    • Expression of Clu and Tgfb1 during murine tooth development: Effects of in -vivo transfection with anti-miR-214
    • Khan QE, Sehic A, Khuu C, Risnes S, Osmundsen H. Expression of Clu and Tgfb1 during murine tooth development: effects of in -vivo transfection with anti-miR-214. Eur J Oral Sci. 2013;121:303-12.
    • (2013) Eur J Oral Sci , vol.121 , pp. 303-312
    • Khan, Q.E.1    Sehic, A.2    Khuu, C.3    Risnes, S.4    Osmundsen, H.5
  • 34
    • 0026570622 scopus 로고
    • Heat shock protein induction in rat hearts. A role for improved myocardial salvage after ischemia and reperfusion?
    • Donnelly TJ, Sievers RE, Vissern FL, Welch WJ, Wolfe CL. Heat shock protein induction in rat hearts. A role for improved myocardial salvage after ischemia and reperfusion? Circulation. 1992;85:769-78.
    • (1992) Circulation , vol.85 , pp. 769-778
    • Donnelly, T.J.1    Sievers, R.E.2    Vissern, F.L.3    Welch, W.J.4    Wolfe, C.L.5
  • 35
    • 0028932259 scopus 로고
    • Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury
    • Marber MS, Mestril R, Chi SH, Sayen MR, Yellon DM, Dillmann WH. Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury. J Clin Invest. 1995;95:1446-56.
    • (1995) J Clin Invest , vol.95 , pp. 1446-1456
    • Marber, M.S.1    Mestril, R.2    Chi, S.H.3    Sayen, M.R.4    Yellon, D.M.5    Dillmann, W.H.6
  • 36
    • 84863600652 scopus 로고    scopus 로고
    • Proteotoxic stress and circulating cell stress proteins in the cardiovascular diseases
    • Henderson B, Pockley AG. Proteotoxic stress and circulating cell stress proteins in the cardiovascular diseases. Cell Stress Chaperones. 2012;17:303-11.
    • (2012) Cell Stress Chaperones , vol.17 , pp. 303-311
    • Henderson, B.1    Pockley, A.G.2
  • 37
    • 71949122628 scopus 로고    scopus 로고
    • Clusterin overexpression and relapse-free survival in breast cancer
    • Yom CK, Woo HY, Min SY, Kang SY, Kim HS. Clusterin overexpression and relapse-free survival in breast cancer. Anticancer Res. 2009;29:3909-12.
    • (2009) Anticancer Res , vol.29 , pp. 3909-3912
    • Yom, C.K.1    Woo, H.Y.2    Min, S.Y.3    Kang, S.Y.4    Kim, H.S.5
  • 38
    • 34548173298 scopus 로고    scopus 로고
    • Multiple pathways regulating the anti-apoptotic protein clusterin in breast cancer
    • Ranney MK, Ahmed IS, Potts KR, Craven RJ. Multiple pathways regulating the anti-apoptotic protein clusterin in breast cancer. Biochim Biophys Acta. 2007;1772:1103-11.
    • (2007) Biochim Biophys Acta , vol.1772 , pp. 1103-1111
    • Ranney, M.K.1    Ahmed, I.S.2    Potts, K.R.3    Craven, R.J.4
  • 39
    • 67650095405 scopus 로고    scopus 로고
    • Roles of clusterin in progression, chemoresistance and metastasis of human ovarian cancer
    • Wei L, Xue T, Wang J, Chen B, Lei Y, Huang Y, et al. Roles of clusterin in progression, chemoresistance and metastasis of human ovarian cancer. Int J Cancer. 2009;125:791-806.
    • (2009) Int J Cancer , vol.125 , pp. 791-806
    • Wei, L.1    Xue, T.2    Wang, J.3    Chen, B.4    Lei, Y.5    Huang, Y.6
  • 41
    • 0037083472 scopus 로고    scopus 로고
    • Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy
    • DOI 10.1002/pros.10047
    • July LV, Akbari M, Zellweger T, Jones EC, Goldenberg SL, Gleave ME. Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy. Prostate. 2002;50:179-88. (Pubitemid 34137445)
    • (2002) Prostate , vol.50 , Issue.3 , pp. 179-188
    • July, L.V.1    Akbari, M.2    Zellweger, T.3    Jones, E.C.4    Goldenberg, S.L.5    Gleave, M.E.6
  • 42
    • 66949123885 scopus 로고    scopus 로고
    • Overexpression of clusterin is a resistance factor to the anti-cancer effect of histone deacetylase inhibitors
    • Liu T, Liu PY, Tee AE, Haber M, Norris MD, Gleave ME, et al. Overexpression of clusterin is a resistance factor to the anti-cancer effect of histone deacetylase inhibitors. Eur J Cancer. 2009;45:1846-54.
    • (2009) Eur J Cancer , vol.45 , pp. 1846-1854
    • Liu, T.1    Liu, P.Y.2    Tee, A.E.3    Haber, M.4    Norris, M.D.5    Gleave, M.E.6
  • 43
    • 80052468423 scopus 로고    scopus 로고
    • Randomized phase II trial of Custirsen (OGX-011) in combination with docetaxel or mitoxantrone as second-line therapy in patients with metastatic castrate-resistant prostate cancer progressing after first-line docetaxel: CUOG trial P-06c
    • Saad F, Hotte S, North S, Eigl B, Chi K, Czaykowski P, et al. Randomized phase II trial of Custirsen (OGX-011) in combination with docetaxel or mitoxantrone as second-line therapy in patients with metastatic castrate-resistant prostate cancer progressing after first-line docetaxel: CUOG trial P-06c. Clin Cancer Res. 2011;17:5765-73.
    • (2011) Clin Cancer Res , vol.17 , pp. 5765-5773
    • Saad, F.1    Hotte, S.2    North, S.3    Eigl, B.4    Chi, K.5    Czaykowski, P.6
  • 44
    • 84857913871 scopus 로고    scopus 로고
    • Phase I/II trial of custirsen (OGX-011), an inhibitor of clusterin, in combination with a gemcitabine and platinum regimen in patients with previously untreated advanced non-small cell lung cancer
    • Laskin JJ, Nicholas G, Lee C, Gitlitz B, Vincent M, Cormier Y, et al. Phase I/II trial of custirsen (OGX-011), an inhibitor of clusterin, in combination with a gemcitabine and platinum regimen in patients with previously untreated advanced non-small cell lung cancer. J Thorac Oncol. 2012;7:579-86.
    • (2012) J Thorac Oncol , vol.7 , pp. 579-586
    • Laskin, J.J.1    Nicholas, G.2    Lee, C.3    Gitlitz, B.4    Vincent, M.5    Cormier, Y.6
  • 45
    • 84862010313 scopus 로고    scopus 로고
    • Clusterin inhibition using OGX-011 synergistically enhances antitumour activity of sorafenib in a human renal cell carcinoma model
    • Kususda Y, Miyake H, Gleave ME, Fujisawa M. Clusterin inhibition using OGX-011 synergistically enhances antitumour activity of sorafenib in a human renal cell carcinoma model. Br J Cancer. 2012;106:1945-52.
    • (2012) Br J Cancer , vol.106 , pp. 1945-1952
    • Kususda, Y.1    Miyake, H.2    Gleave, M.E.3    Fujisawa, M.4
  • 46
    • 80051547555 scopus 로고    scopus 로고
    • Glucose-regulated protein 78 (GRP78) mediated the efficacy to curcumin treatment on hepatocellular carcinoma
    • Chang YJ, Tai CJ, Kuo LJ, Wei PL, Liang HH, Liu TZ, et al. Glucose-regulated protein 78 (GRP78) mediated the efficacy to curcumin treatment on hepatocellular carcinoma. Ann Surg Oncol. 2011;18:2395-403.
    • (2011) Ann Surg Oncol , vol.18 , pp. 2395-2403
    • Chang, Y.J.1    Tai, C.J.2    Kuo, L.J.3    Wei, P.L.4    Liang, H.H.5    Liu, T.Z.6
  • 47
    • 84874006813 scopus 로고    scopus 로고
    • Clusterin protects hepatocellular carcinoma cells from endoplasmic reticulumstress induced apoptosis through GRP78
    • Wang C, Jiang K, Gao D, Kang X, Sun C, Zhang Q, et al. Clusterin protects hepatocellular carcinoma cells from endoplasmic reticulumstress induced apoptosis through GRP78. PLoS One. 2013; 8:e55981.
    • (2013) PLoS One , vol.8
    • Wang, C.1    Jiang, K.2    Gao, D.3    Kang, X.4    Sun, C.5    Zhang, Q.6
  • 48
  • 49
    • 58849123363 scopus 로고    scopus 로고
    • Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex
    • Trougakos IP, Lourda M, Antonelou MH, Kletsas D, Gorgoulis VG, Papassideri IS, et al. Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex. Clin Cancer Res. 2009;15:48-59.
    • (2009) Clin Cancer Res , vol.15 , pp. 48-59
    • Trougakos, I.P.1    Lourda, M.2    Antonelou, M.H.3    Kletsas, D.4    Gorgoulis, V.G.5    Papassideri, I.S.6
  • 51
    • 80053583151 scopus 로고    scopus 로고
    • Apolipoprotein J/Clusterin is a novel structural component of human erythrocytes and a biomarker of cellular stress and senescence
    • Antonelou MH, Kriebardis AG, Stamoulis KE, Trougakos IP, Papassideri IS. Apolipoprotein J/Clusterin is a novel structural component of human erythrocytes and a biomarker of cellular stress and senescence. PLoS One. 2011;6:e26032.
    • (2011) PLoS One , vol.6
    • Antonelou, M.H.1    Kriebardis, A.G.2    Stamoulis, K.E.3    Trougakos, I.P.4    Papassideri, I.S.5
  • 52
    • 0041347519 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in cancer therapy: Is transcription the primary target?
    • DOI 10.1016/S1535-6108(03)00165-X
    • Johnstone RW, Licht JD. Histone deacetylase inhibitors in cancer therapy: is transcription the primary target? Cancer Cell. 2003;4:13-8. (Pubitemid 36904157)
    • (2003) Cancer Cell , vol.4 , Issue.1 , pp. 13-18
    • Johnstone, R.W.1    Licht, J.D.2
  • 53
    • 84155184197 scopus 로고    scopus 로고
    • Human nuclear clusterin mediates apoptosis by interacting with Bcl-XL through C-terminal coiled coil domain
    • Kim N, Yoo JC, Han JY, Hwang EM, Kim YS, Jeong EY, et al. Human nuclear clusterin mediates apoptosis by interacting with Bcl-XL through C-terminal coiled coil domain. J Cell Physiol. 2012;227: 1157-67.
    • (2012) J Cell Physiol , vol.227 , pp. 1157-1167
    • Kim, N.1    Yoo, J.C.2    Han, J.Y.3    Hwang, E.M.4    Kim, Y.S.5    Jeong, E.Y.6
  • 55
    • 79956130567 scopus 로고    scopus 로고
    • Association of the clusterin gene polymorphisms with type 2 diabetes mellitus
    • Daimon M, Oizumi T, Karasawa S, Kaino W, Takase K, Tada K, et al. Association of the clusterin gene polymorphisms with type 2 diabetes mellitus. Metabolism. 2011;60:815-22.
    • (2011) Metabolism , vol.60 , pp. 815-822
    • Daimon, M.1    Oizumi, T.2    Karasawa, S.3    Kaino, W.4    Takase, K.5    Tada, K.6
  • 58
    • 79956213385 scopus 로고    scopus 로고
    • Interaction of a putative BH3 domain of clusterin with anti-apoptotic Bcl-2 family proteins as revealed by NMR spectroscopy
    • Lee DH, Ha JH, KimY, Bae KH, Park JY, Choi WS, et al. Interaction of a putative BH3 domain of clusterin with anti-apoptotic Bcl-2 family proteins as revealed by NMR spectroscopy. Biochem Biophys Res Commun. 2011;408:541-7.
    • (2011) Biochem Biophys Res Commun , vol.408 , pp. 541-547
    • Lee, D.H.1    Ha, J.H.2    Kim, Y.3    Bae, K.H.4    Park, J.Y.5    Choi, W.S.6
  • 59
    • 0035876483 scopus 로고    scopus 로고
    • BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
    • DOI 10.1101/gad.897601
    • Zong WX, Lindsten T, Ross AJ, MacGregor GR, Thompson CB. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev. 2001;15:1481-6. (Pubitemid 32552527)
    • (2001) Genes and Development , vol.15 , Issue.12 , pp. 1481-1486
    • Zong, W.-X.1    Lindsten, T.2    Ross, A.J.3    MacGregor, G.R.4    Thompson, C.B.5
  • 60
    • 84867148236 scopus 로고    scopus 로고
    • The impact of lipoic acid on endothelial function and proteinuria in quinapril-treated diabetic patients with stage I hypertension: Results from the QUALITY study
    • Rahman ST, Merchant N, Haque T, Wahi J, Bhaheetharan S, Ferdinand KC, et al. The impact of lipoic acid on endothelial function and proteinuria in quinapril-treated diabetic patients with stage I hypertension: results from the QUALITY study. J Cardiovasc Pharmacol Ther. 2012;17:139-45.
    • (2012) J Cardiovasc Pharmacol Ther , vol.17 , pp. 139-145
    • Rahman, S.T.1    Merchant, N.2    Haque, T.3    Wahi, J.4    Bhaheetharan, S.5    Ferdinand, K.C.6
  • 61
    • 77952966112 scopus 로고    scopus 로고
    • Oxidized LDL: Diversity, patterns of recognition, and pathophysiology
    • Levitan I, Volkov S, Subbaiah PV. Oxidized LDL: diversity, patterns of recognition, and pathophysiology. Antioxid Redox Signal. 2010;13:39-75.
    • (2010) Antioxid Redox Signal , vol.13 , pp. 39-75
    • Levitan, I.1    Volkov, S.2    Subbaiah, P.V.3
  • 63
    • 4544383898 scopus 로고    scopus 로고
    • Oral D-4F causes formation of pre-beta highdensity lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice
    • Navab M, Anantharamaiah GM, Reddy ST, Hama S, Hough G, Grijalva VR, et al. Oral D-4F causes formation of pre-beta highdensity lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice. Circulation. 2004;109:3215-20.
    • (2004) Circulation , vol.109 , pp. 3215-3220
    • Navab, M.1    Anantharamaiah, G.M.2    Reddy, S.T.3    Hama, S.4    Hough, G.5    Grijalva, V.R.6
  • 64
    • 45149104050 scopus 로고    scopus 로고
    • Clusterin activates survival through the phosphatidylinositol 3-kinase/Akt pathway
    • Ammar H, Closset JL. Clusterin activates survival through the phosphatidylinositol 3-kinase/Akt pathway. J Biol Chem. 2008;283:12851-61.
    • (2008) J Biol Chem , vol.283 , pp. 12851-12861
    • Ammar, H.1    Closset, J.L.2
  • 66
    • 70349564793 scopus 로고    scopus 로고
    • Protective role of clusterin/apolipoprotein J against neointimal hyperplasia via antiproliferative effect on vascular smooth muscle cells and cytoprotective effect on endothelial cells
    • Kim HJ, Yoo EK, Kim JY, Choi YK, Lee HJ, Kim JK, et al. Protective role of clusterin/apolipoprotein J against neointimal hyperplasia via antiproliferative effect on vascular smooth muscle cells and cytoprotective effect on endothelial cells. Arterioscler Thromb Vasc Biol. 2009;29:1558-64.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1558-1564
    • Kim, H.J.1    Yoo, E.K.2    Kim, J.Y.3    Choi, Y.K.4    Lee, H.J.5    Kim, J.K.6
  • 68
    • 0034141470 scopus 로고    scopus 로고
    • Laminar shear stress upregulates the complement-inhibitory protein clusterin. A novel potent defense mechanism against complement-induced endothelial cell activation
    • Urbich C, Fritzenwanger M, Zeiher AM, Dimmeler S. Laminar shear stress upregulates the complement-inhibitory protein clusterin : a novel potent defense mechanism against complement-induced endothelial cell activation. Circulation. 2000;101:352-5. (Pubitemid 30067388)
    • (2000) Circulation , vol.101 , Issue.4 , pp. 352-355
    • Urbich, C.1    Fritzenwanger, M.2    Zeiher, A.M.3    Dimmeler, S.4
  • 69
    • 79953309539 scopus 로고    scopus 로고
    • Loss of clusterin limits atherosclerosis in apolipoprotein E-deficient mice via reduced expression of Egr-1 and TNF-alpha
    • Hamada N, Miyata M, Eto H, Ikeda Y, Shirasawa T, Akasaki Y, et al. Loss of clusterin limits atherosclerosis in apolipoprotein E-deficient mice via reduced expression of Egr-1 and TNF-alpha. J Atheroscler Thromb. 2011;18:209-16.
    • (2011) J Atheroscler Thromb , vol.18 , pp. 209-216
    • Hamada, N.1    Miyata, M.2    Eto, H.3    Ikeda, Y.4    Shirasawa, T.5    Akasaki, Y.6
  • 70
    • 36349016509 scopus 로고    scopus 로고
    • Mitochondrial complex II in the post-ischemic heart: Oxidative injury and the role of protein S-glutathionylation
    • DOI 10.1074/jbc.M702294200
    • Chen YR, Chen CL, Pfeiffer DR, Zweier JL.Mitochondrial complex II in the post-ischemic heart: oxidative injury and the role of protein S-glutathionylation. J Biol Chem. 2007;282:32640-54. (Pubitemid 350159288)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.45 , pp. 32640-32654
    • Chen, Y.-R.1    Chen, C.-L.2    Pfeiffer, D.R.3    Zweier, J.L.4
  • 71
    • 84879881195 scopus 로고    scopus 로고
    • Ambient ultrafine particles reduce endothelial nitric oxide production via Sglutathionylation of eNOS
    • Du Y, Navab M, Shen M, Hill J, Pakbin P, Sioutas C, et al. Ambient ultrafine particles reduce endothelial nitric oxide production via Sglutathionylation of eNOS. Biochem Biophys Res Commun. 2013; 436:462-6.
    • (2013) Biochem Biophys Res Commun , vol.436 , pp. 462-466
    • Du, Y.1    Navab, M.2    Shen, M.3    Hill, J.4    Pakbin, P.5    Sioutas, C.6
  • 72
    • 82955225246 scopus 로고    scopus 로고
    • Proteomic analysis of intra-arterial thrombus secretions reveals a negative association of clusterin and thrombospondin-1 with abdominal aortic aneurysm
    • Moxon JV, Padula MP, Clancy P, Emeto TI, Herbert BR, Norman PE, et al. Proteomic analysis of intra-arterial thrombus secretions reveals a negative association of clusterin and thrombospondin-1 with abdominal aortic aneurysm. Atherosclerosis. 2011;219:432-9.
    • (2011) Atherosclerosis , vol.219 , pp. 432-439
    • Moxon, J.V.1    Padula, M.P.2    Clancy, P.3    Emeto, T.I.4    Herbert, B.R.5    Norman, P.E.6
  • 73
    • 19744378213 scopus 로고    scopus 로고
    • Heart failure
    • DOI 10.1016/S0140-6736(05)66621-4, PII S0140673605666214
    • McMurray JJ, PfefferMA. Heart failure. Lancet. 2005;365:1877-89. (Pubitemid 40744967)
    • (2005) Lancet , vol.365 , Issue.9474 , pp. 1877-1889
    • McMurray, J.J.V.1    Pfeffer, M.A.2
  • 75
    • 0029792679 scopus 로고    scopus 로고
    • Low density lipoprotein receptor-related protein-2 expression in efferent duct and epididymal epithelia: Evidence in rats for its in vivo role in endocytosis of apolipoprotein J/clusterin
    • Morales CR, Igdoura SA, Wosu UA, Boman J, Argraves WS. Low density lipoprotein receptor-related protein-2 expression in efferent duct and epididymal epithelia: evidence in rats for its in vivo role in endocytosis of apolipoprotein J/clusterin. Biol Reprod. 1996;55:676-83. (Pubitemid 26295069)
    • (1996) Biology of Reproduction , vol.55 , Issue.3 , pp. 676-683
    • Morales, C.R.1    Igdoura, S.A.2    Wosu, U.A.3    Boman, J.4    Argraves, W.S.5
  • 76
    • 40549135297 scopus 로고    scopus 로고
    • Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: Lessons from genetically engineered mice
    • DOI 10.1172/JCI34275
    • Postic C, Girard J. Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. J Clin Invest. 2008;118:829-38. (Pubitemid 351364588)
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.3 , pp. 829-838
    • Postic, C.1    Girard, J.2
  • 77
    • 34547102250 scopus 로고    scopus 로고
    • Expression of the rat sterol regulatory element-binding protein-1c gene in response to insulin is mediated by increased transactivating capacity of specificity protein 1 (Sp1)
    • DOI 10.1074/jbc.M702228200
    • Deng X, Yellaturu C, Cagen L, Wilcox HG, Park EA, Raghow R, et al. Expression of the rat sterol regulatory element-binding protein-1c gene in response to insulin is mediated by increased transactivating capacity of specificity protein 1 (Sp1). J Biol Chem. 2007;282:17517-29. (Pubitemid 47100272)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.24 , pp. 17517-17529
    • Deng, X.1    Yellaturu, C.2    Cagen, L.3    Wilcox, H.G.4    Park, E.A.5    Raghow, R.6    Elam, M.B.7
  • 79
    • 84876746246 scopus 로고    scopus 로고
    • Clusterin decreases hepatic SREBP-1c expression and lipid accumulation
    • Seo HY, Kim MK, Jung YA, Jang BK, Yoo EK, Park KG, et al. Clusterin decreases hepatic SREBP-1c expression and lipid accumulation. Endocrinology. 2013;154:1722-30.
    • (2013) Endocrinology , vol.154 , pp. 1722-1730
    • Seo, H.Y.1    Kim, M.K.2    Jung, Y.A.3    Jang, B.K.4    Yoo, E.K.5    Park, K.G.6
  • 81
    • 21344432100 scopus 로고    scopus 로고
    • Role of selective leptin resistance in diet-induced obesity hypertension
    • DOI 10.2337/diabetes.54.7.2012
    • Rahmouni K, Morgan DA, Morgan GM, Mark AL, Haynes WG. Role of selective leptin resistance in diet-induced obesity hypertension. Diabetes. 2005;54:2012-8. (Pubitemid 40911263)
    • (2005) Diabetes , vol.54 , Issue.7 , pp. 2012-2018
    • Rahmouni, K.1    Morgan, D.A.2    Morgan, G.M.3    Mark, A.L.4    Haynes, W.G.5
  • 82
    • 79954701326 scopus 로고    scopus 로고
    • Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation
    • Harlan SM, Morgan DA, Agassandian K, Guo DF, Cassell MD, Sigmund CD, et al. Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation. Circ Res. 2011;108:808-12.
    • (2011) Circ Res , vol.108 , pp. 808-812
    • Harlan, S.M.1    Morgan, D.A.2    Agassandian, K.3    Guo, D.F.4    Cassell, M.D.5    Sigmund, C.D.6
  • 83
    • 84877260638 scopus 로고    scopus 로고
    • Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice
    • Lin Z, Tian H, Lam KS, Lin S, Hoo RC, Konishi M, et al. Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice. Cell Metab. 2013;17:779-89.
    • (2013) Cell Metab , vol.17 , pp. 779-789
    • Lin, Z.1    Tian, H.2    Lam, K.S.3    Lin, S.4    Hoo, R.C.5    Konishi, M.6
  • 84
  • 85
    • 0041703035 scopus 로고    scopus 로고
    • A model for modulation of leptin activity by association with clusterin
    • Bajari TM, Strasser V, Nimpf J, Schneider WJ. A model for modulation of leptin activity by association with clusterin. FASEB J. 2003;17:1505-7.
    • (2003) FASEB J , vol.17 , pp. 1505-1507
    • Bajari, T.M.1    Strasser, V.2    Nimpf, J.3    Schneider, W.J.4
  • 86
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • DOI 10.1038/27376
    • Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature. 1998;395:763-70. (Pubitemid 28485436)
    • (1998) Nature , vol.395 , Issue.6704 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 88
    • 84878738666 scopus 로고    scopus 로고
    • Clusterin and LRP2 are critical components of the hypothalamic feeding regulatory pathway
    • Gil SY, Youn BS, Byun K, Huang H, Namkoong C, Jang PG, et al. Clusterin and LRP2 are critical components of the hypothalamic feeding regulatory pathway. Nat Commun. 2013;4:1862.
    • (2013) Nat Commun , vol.4 , pp. 1862
    • Gil, S.Y.1    Youn, B.S.2    Byun, K.3    Huang, H.4    Namkoong, C.5    Jang, P.G.6
  • 91
    • 56349091404 scopus 로고    scopus 로고
    • The effects of ACE inhibitor and angiotensin receptor blocker on clusterin and apoptosis in the kidney tissue of streptozotocin-diabetic rats
    • Tuncdemir M, Ozturk M. The effects of ACE inhibitor and angiotensin receptor blocker on clusterin and apoptosis in the kidney tissue of streptozotocin-diabetic rats. J Mol Histol. 2008;39:605-16.
    • (2008) J Mol Histol , vol.39 , pp. 605-616
    • Tuncdemir, M.1    Ozturk, M.2
  • 92
    • 77957730965 scopus 로고    scopus 로고
    • Genome-wide association studies in Alzheimer's disease
    • Bertram L, Tanzi RE. Genome-wide association studies in Alzheimer's disease. Hum Mol Genet. 2009;18:R137-45.
    • (2009) Hum Mol Genet , vol.18
    • Bertram, L.1    Tanzi, R.E.2
  • 93
    • 0029920929 scopus 로고    scopus 로고
    • Glycoprotein 330/megalin: Probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers
    • Zlokovic BV, Martel CL, Matsubara E, McComb JG, Zheng G, McCluskey RT, et al. Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers. Proc Natl Acad Sci U S A. 1996;93:4229-34.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 4229-4234
    • Zlokovic, B.V.1    Martel, C.L.2    Matsubara, E.3    McComb, J.G.4    Zheng, G.5    McCluskey, R.T.6
  • 94
    • 4444276735 scopus 로고    scopus 로고
    • Clearance of Alzheimer's Abeta peptide: The many roads to perdition
    • DOI 10.1016/j.neuron.2004.08.024, PII S0896627304005331
    • Tanzi RE, Moir RD, Wagner SL. Clearance of Alzheimer's Abeta peptide: the many roads to perdition. Neuron. 2004;43: 605-8. (Pubitemid 39179722)
    • (2004) Neuron , vol.43 , Issue.5 , pp. 605-608
    • Tanzi, R.E.1    Moir, R.D.2    Wagner, S.L.3


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