Pharmacologic repression of retinoic acid receptor-related orphan nuclear receptor γ is therapeutic in the collagen-induced arthritis experimental model

Arthritis and Rheumatology

Volumn 66, Issue 3, 2014, Pages 579-588

  Chang, Mi Ra ^a   Lyda, Brent ^a   Kamenecka, Theodore M ^a   Griffin, Patrick R ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; CD14 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; DEXAMETHASONE; ENHANCED GREEN FLUORESCENT PROTEIN; G PROTEIN COUPLED RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; RETINOIC ACID RECEPTOR; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; SR 1555; SR 2211; SR1555; SR2211; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR GAL4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; B LYMPHOCYTE; CELL ACTIVATION; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; ENZYME REPRESSION; FEMALE; HISTOPATHOLOGY; IC 50; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH17 CELL; TREATMENT DURATION;

ANIMALS; ARTHRITIS, EXPERIMENTAL; CELL DIFFERENTIATION; CELL LINE; CYTOKINES; INTERLEUKIN-17; MICE; MICE, INBRED DBA; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; PIPERAZINES; PROPANOLS; TH17 CELLS;

EID: 84896287211     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.38272     Document Type: Article

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