Macrophages from human pluripotent stem cells

Handbook of Macrophages: Life Cycle, Functions and Diseases

Volumn , Issue , 2012, Pages 83-120

  Cowley, Sally A ^a   Karlsson, Karl R ^a   van Wilgenburg, Bonnie ^a   Carter, Gemma C ^a   Browne, Cathy ^a   Vowles, Jane ^a   Estrada, Fernando Martinez ^a   Pelchen Matthews, Annegret ^b   Miller, Joanna ^c   Moore, Michael D ^a   James, William ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84896209464     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (69)

1. Thomson J, Itskovitz-Eldor J, Shapiro S, Waknitz M, Swiergiel J, Marshall V, et al. Embryonic Stem Cell Lines Derived from Human Blastocysts. Science. 1998;282(5391):1145-7.
2. Takahashi K, Yamanaka S. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors. Cell. 2006;126(4):663-76.
3. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, et al. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors. Cell. 2007;131(5):861-72.
4. Yu J, Vodyanik M, Smuga-Otto K, Antosiewicz-Bourget J, Frane J, Tian S, et al. Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells. Science. 2007;318(5858):1917-20.
5. Park I-H, Lerou P, Zhao R, Huo H, Daley G. Generation of human-induced pluripotent stem cells. Nature Protocols. 2008;3(7):1180-6.
6. Cowley S. Induced pluripotent stem cells and their application into personalised therapy. Elsevier; 2011.
7. Hu B-Y, Weick J, Yu J, Ma L-X, Zhang X-Q, Thomson J, et al. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proceedings of the National Academy of Sciences. 2010;107(9):4335-40.
8. Karlsson K, Cowley S, Martinez F, Shaw M, Minger S, James W. Homogeneous monocytes and macrophages from human embryonic stem cells following coculturefree differentiation in M-CSF and IL-3. Experimental hematology. 2008;36(9):1167-75.
9. Subramanian A, Guo B, Marsden M, Galic Z, Kitchen S, Kacena A, et al. Macrophage differentiation from embryoid bodies derived from human embryonic stem cells. Journal of stem cells. 2009;4(1):29-45.
10. Anderson J, Bandi S, Kaufman D, Akkina R. Derivation of normal macrophages from human embryonic stem (hES) cells for applications in HIV gene therapy. Retrovirology. 2006;3(1):24.
11. Kambal A, Mitchell G, Cary W, Gruenloh W, Jung Y, Kalomoiris S, et al. Generation of HIV-1 Resistant and Functional Macrophages From Hematopoietic Stem Cellderived Induced Pluripotent Stem Cells. Mol. Ther. 2011;19(3):584-93.
12. Senju S, Haruta M, Matsumura K, Matsunaga Y, Fukushima S, Ikeda T, et al. Generation of dendritic cells and macrophages from human induced pluripotent stem cells aiming at cell therapy. Gene Therapy. 2011.
13. Choi K-D, Vodyanik M, Slukvin I. Hematopoietic differentiation and production of mature myeloid cells from human pluripotent stem cells. Nature Protocols. 2011;6(3):296-313.
14. Cobos-Jiménez V, Booiman T, Hamann J, Kootstra N. Macrophages and HIV-1. Current opinion in HIV and AIDS. 2011;6(5):385-90.
15. Carter G, Bernstone L, Sangani D, Bee J, Harder T, James W. HIV entry in macrophages is dependent on intact lipid rafts. Virology. 2009;386(1):192-202.
16. Carter G, Bernstone L, Baskaran D, James W. HIV-1 infects macrophages by exploiting an endocytic route dependent on dynamin, Rac1 and Pak1. Virology. 2011;409(2):234-50.
17. Durbin AP, Vargas MJ, Wanionek K, Hammond SN, Gordon A, Rocha C, et al. Phenotyping of peripheral blood mononuclear cells during acute dengue illness demonstrates infection and increased activation of monocytes in severe cases compared to classic dengue fever. Virology. 2008 Jul 5;376(2):429-35.
18. Kou Z, Quinn M, Chen H, Rodrigo WW, Rose RC, Schlesinger JJ, et al. Monocytes, but not T or B cells, are the principal target cells for dengue virus (DV) infection among human peripheral blood mononuclear cells. J. Med. Virol. 2008 Jan;80(1):134-46.
19. Balsitis SJ, Coloma J, Castro G, Alava A, Flores D, McKerrow JH, et al. Tropism of dengue virus in mice and humans defined by viral nonstructural protein 3-specific immunostaining. Am. J. Trop. Med. Hyg.. 2009 Mar;80(3):416-24.
20. Jessie K, Fong MY, Devi S, Lam SK, Wong T. Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in situ hybridization. The Journal of infectious diseases. 2004;189(8):1411-8.
21. Dejnirattisai W, Jumnainsong A, Onsirisakul N, Fitton P, Vasanawathana S, Limpitikul W, et al. Cross-reacting antibodies enhance dengue virus infection in humans. Science. 2010 May 7;328(5979):745-8.
22. Miller JL, de Wet BJ, Martinez-Pomares L, Radcliffe CM, Dwek RA, Rudd PM, et al. The mannose receptor mediates dengue virus infection of macrophages. PLoS. Pathog. 2008 Feb 8;4(2):e17.
23. Peiris JS, Porterfield JS. Antibody-mediated enhancement of Flavivirus replication in macrophage-like cell lines. Nature. 1979;282(5738): 509-11.
24. Schieffelin JS, Costin JM, Nicholson CO, Orgeron NM, Fontaine KA, Isern S, et al. Neutralizing and non-neutralizing monoclonal antibodies against dengue virus E protein derived from a naturally infected patient. Virol J. 2010;7:28.
25. Bosch I, Xhaja K, Estevez L, Raines G, Melichar H, Warke RV, et al. Increased production of interleukin-8 in primary human monocytes and in human epithelial and endothelial cell lines after dengue virus challenge. J. Virol. 2002 Jun;76(11):5588-97.
26. Carr JM, Hocking H, Bunting K, Wright PJ, Davidson A, Gamble J, et al. Supernatants from dengue virus type-2 infected macrophages induce permeability changes in endothelial cell monolayers. J. Med. Virol. 2003 Apr;69(4):521-8.
27. Fink K, Ng C, Nkenfou C, Vasudevan SG, van Rooijen N, Schul W. Depletion of macrophages in mice results in higher dengue virus titers and highlights the role of macrophages for virus control. Eur. J. Immunol. 2009 Oct;39(10):2809-21.
28. Halstead SB. Antibody, macrophages, dengue virus infection, shock, and hemorrhage: a pathogenetic cascade. Rev Infect Dis. 1989 May-Jun;11 Suppl. 4:S830-9.
29. Sun P, Bauza K, Pal S, Liang Z, Wu S-j, Beckett C, et al. Infection and activation of human peripheral blood monocytes by dengue viruses through the mechanism of antibody-dependent enhancement. Virology. 2011;421(2):245-52.
30. Robertson NJ, Brook FA, Gardner RL, Cobbold SP, Waldmann H, Fairchild PJ. Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of tolerance. Proc. Natl. Acad. Sci. USA. 2007 Dec 26;104(52):20920-5.
31. Archbold JK, Ely LK, Kjer-Nielsen L, Burrows SR, Rossjohn J, McCluskey J, et al. T cell allorecognition and MHC restriction--A case of Jekyll and Hyde? Mol. Immunol. 2008 Feb;45(3):583-98.
32. Munn DH, Shafizadeh E, Attwood JT, Bondarev I, Pashine A, Mellor AL. Inhibition of T cell proliferation by macrophage tryptophan catabolism. The Journal of experimental medicine. 1999;189(9):1363-72.
33. Verreck FA, de Boer T, Langenberg DM, van der Zanden L, Ottenhoff TH. Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-{gamma}- and CD40Lmediated costimulation. J. Leukoc. Biol. 2005 Dec 5.
34. Xu W, Schlagwein N, Roos A, van den Berg TK, Daha MR, van Kooten C. Human peritoneal macrophages show functional characteristics of M-CSF-driven antiinflammatory type 2 macrophages. Eur. J. Immunol. 2007 May 2.
35. Cowan CA, Klimanskaya I, McMahon J, Atienza J, Witmyer J, Zucker JP, et al. Derivation of embryonic stem-cell lines from human blastocysts. N. Engl. J. Med. 2004 Mar 25;350(13):1353-6.
36. Yu J, Hu K, Smuga-Otto K, Tian S, Stewart R, Slukvin I, et al. Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences. Science. 2009;324(5928):797-801.
37. Zufferey R, Nagy D, Mandel RJ, Naldini L, Trono D. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nature Biotechnology. 1997;15(9):871-5.
38. Demaison C, Parsley K, Brouns G, Scherr M, Battmer K, Kinnon C, et al. High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter. Human gene. therapy. 2002;13(7):803-13.
39. Ehrhardt C, Schmolke M, Matzke A, Knoblauch A, Will C, Wixler V, et al. Polyethylenimine, a cost-effective transfection reagent. Signal Transduction. 2006;6(3):179-84.
40. Karlsson H, Samarasinghe S, Ball LM, Sundberg B, Lankester AC, Dazzi F, et al. Mesenchymal stem cells exert differential effects on alloantigen and virus-specific T cell responses. Blood. 2008 Apr 29.
41. Gartner S, Markovits P, Markovitz DM, Betts RF, Popovic M. Virus isolation from and identification of HTLV-III/LAV-producing cells in brain tissue from a patient with AIDS. JAMA: the journal of the American Medical Association. 1986;256(17):2365-71.
42. Gendelman HE, Orenstein JM, Martin MA, Ferrua C, Mitra R, Phipps T, et al. Efficient isolation and propagation of human immunodeficiency virus on recombinant colonystimulating factor 1-treated monocytes. J. Exp. Med. 1988 Apr 1;167(4):1428-41.
43. Koyanagi Y, Miles S, Mitsuyasu RT, Merrill JE, Vinters HV, Chen IS. Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science. 1987 May 15;236(4803):819-22.
44. Collman R, Balliet JW, Gregory SA, Friedman H, Kolson DL, Nathanson N, et al. An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1. J. Virol. 1992 Dec;66(12):7517-21.
45. He J, Choe S, Walker R, Di Marzio P, Morgan DO, Landau NR. Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity. J. Virol. 1995 Nov;69(11):6705-11.
46. Matlin KS, Reggio H, Helenius A, Simons K. Pathway of vesicular stomatitis virus entry leading to infection. J. Mol. Biol. 1982 Apr 15;156(3):609-31.
47. Yamada S, Ohnishi S. Vesicular stomatitis virus binds and fuses with phospholipid domain in target cell membranes. Biochemistry. 1986 Jun 17;25(12):3703-8.
48. Pelchen-Matthews A, Marsh M. Electron microscopy analysis of viral morphogenesis. Methods in cell biology. 2007;79:515-42.
49. Pelchen-Matthews A, Kramer B, Marsh M. Infectious HIV-1 assembles in late endosomes in primary macrophages. J. Cell. Biol. 2003;162(3):443-55.
50. Deneka M, Pelchen-Matthews A, Byland R, Ruiz-Mateos E, Marsh M. In macrophages, HIV-1 assembles into an intracellular plasma membrane domain containing the tetraspanins CD81, CD9, and CD53. The Journal of cell biology. 2007;177(2):329-41.
51. Welsch S, Keppler O, Habermann A, Allespach I, Krijnse-Locker J, Kräusslich H-G. HIV-1 buds predominantly at the plasma membrane of primary human macrophages. PLoS pathogens. 2007;3(3).
52. Marsh M, Theusner K, Pelchen-Matthews A. HIV assembly and budding in macrophages. Biochemical Society transactions. 2009;37(Pt 1):185-9.
53. Pelchen-Matthews A, Giese S, Mlčochová P, Turner J, Marsh M. β2 Integrin Adhesion Complexes Maintain the Integrity of HIV-1 Assembly Compartments in Primary Macrophages. Traffic. 2012;13(2):273-91.
54. Miller J, de Wet B, Martinez-Pomares L, Radcliffe C, Dwek R, et al. The mannose receptor mediates dengue virus infection of macrophages. PLoS. pathogens. 2008;4(2).
55. Chan E, Ratanasirintrawoot S, Park I-H, Manos P, Loh Y-H, Huo H, et al. Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells. Nat. Biotech. 2009;27(11):1033-7.
56. Karlsson KR, Cowley S, Martinez FO, Shaw M, Minger SL, James W. Homogeneous monocytes and macrophages from human embryonic stem cells following coculturefree differentiation in M-CSF and IL-3. Exp. Hematol. 2008;36(9):1167-1175.
57. Young DA, Lowe LD, Clark SC. Comparison of the effects of IL-3, granulocytemacrophage colony-stimulating factor, and macrophage colony-stimulating factor in supporting monocyte differentiation in culture. Analysis of macrophage antibodydependent cellular cytotoxicity. J. Immunol. 1990 Jul 15;145(2):607-15.
58. Smith W, Feldmann M, Londei M. Human macrophages induced in vitro by macrophage colony-stimulating factor are deficient in IL-12 production. Eur. J. Immunol. 1998 Aug;28(8):2498-507.
59. Brook FA, Cowley S, Evans E, Turner K, James W, Mardon H. Derivation and characterisation of the human embryonic stem cell line, OxF1. In vitro cellular and developmental biology Animal. 2010;46(3-4):173-7.
60. Armstrong L, Tilgner K, Saretzki G, Atkinson S, Stojkovic M, Moreno R, et al. Human Induced Pluripotent Stem Cell Lines Show Stress Defense Mechanisms and Mitochondrial Regulation Similar to Those of Human Embryonic Stem Cells. STEM CELLS. 2010;28(4):661-73.
61. Zhou L, Sokolskaja E, Jolly C, James W, Cowley S, Fassati A. Transportin 3 Promotes a Nuclear Maturation Step Required for Efficient HIV-1 Integration. PLoS Pathog. 2011;7(8):e1002194.
62. Sessions O, Barrows N, Souza-Neto J, Robinson T, Hershey C, Rodgers M, et al. Discovery of insect and human dengue virus host factors. Nature. 2009;458(7241):1047-50.
63. Khor CC, Chau TNB, Pang J, Davila S, Long HT, Ong R, et al. Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1. Nature genetics. 2011;43(11):1139-41.
64. Gordon S, Martinez F. Alternative Activation of Macrophages: Mechanism and Functions. Immunity. 2010;32(5):593-604.
65. Gabrilovich D, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nature reviews Immunology. 2009;9(3):162-74.
66. Li M, Suzuki K, Qu J, Saini P, Dubova I, Yi F, et al. Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs. Cell Research. 2011;21(12):1740-4.
67. Yusa K, Rashid T, Strick-Marchand H, Varela I, Liu P-Q, Paschon D, et al. Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells. Nature. 2011;478(7369):391-4.
68. Liu G-H, Sancho-Martinez I, Belmonte JCI. Cut and Paste: restoring cellular function by gene correction. Cell Research. 2011.
69. Zou J, Sweeney C, Chou B-K, Choi U, Pan J, Wang H, et al. Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting. Blood. 2011;117(21):5561-72.