Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of tolerance

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 52, 2007, Pages 20920-20925

  Robertson, Nathan J ^a   Brook, Frances A ^b   Gardner, Richard L ^b   Cobbold, Stephen P ^a   Waldmann, Herman ^a   Fairchild, Paul J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Acquired immune privilege; Cell replacement therapy; Regulatory T cell

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; MINOR HISTOCOMPATIBILITY ANTIGEN; TRANSFORMING GROWTH FACTOR BETA2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYONIC STEM CELL; GRAFT REJECTION; IMMUNOGENICITY; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; STEM CELL TRANSPLANTATION; T LYMPHOCYTE;

ANIMALS; ANTIBODIES, MONOCLONAL; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; EMBRYONIC STEM CELLS; GRAFT SURVIVAL; HUMANS; IMMUNE SYSTEM; IMMUNE TOLERANCE; KINETICS; MICE; MICE, INBRED C57BL; MINOR HISTOCOMPATIBILITY ANTIGENS; MODELS, BIOLOGICAL; SKIN; TRANSFORMING GROWTH FACTOR BETA2;

EID: 38049181036     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0710265105     Document Type: Article

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