Depletion of macrophages in mice results in higher dengue virus titers and highlights the role of macrophages for virus control

European Journal of Immunology

Volumn 39, Issue 10, 2009, Pages 2809-2821

  Fink, Katja ^a,b   Ng, Cedrig ^a   Nkenfou, Celine ^a,c,d   Vasudevan, Subhash G ^a,e   Van Rooijen, Nico ^f   Schul, Wouter ^a  

^a NOVARTIS INSTITUTE FOR TROPICAL DISEASES   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

^c Molecular Biology Center   (Cameroon)

^d UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^e DUKE NUS MEDICAL SCHOOL   (Singapore)

^f VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Dengue virus; Host pathogen interactions; Macrophages; Monocytes

Indexed keywords

ALPHA INTERFERON RECEPTOR; BETA INTERFERON RECEPTOR; CD11B ANTIGEN; GAMMA INTERFERON RECEPTOR; GLYCOPROTEIN P 15095;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DENGUE; DENGUE VIRUS; IN VIVO STUDY; KNOCKOUT MOUSE; LYMPH NODE; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIREMIA; VIRUS IMMUNITY; VIRUS REPLICATION; VIRUS TITRATION;

ANIMALS; CELL COUNT; CELL MOVEMENT; CLODRONIC ACID; DENGUE; DENGUE VIRUS; EPIDERMIS; GRANULOCYTES; LANGERHANS CELLS; LIPOSOMES; LYMPH; LYMPH NODES; LYMPHOID TISSUE; MACROPHAGES; MICE; MICE, INBRED STRAINS; MICE, KNOCKOUT; MONOCYTES; PERITONEUM; RECEPTOR, INTERFERON ALPHA-BETA; RECEPTORS, INTERFERON; SPLEEN; VIRAL LOAD; VIRAL NONSTRUCTURAL PROTEINS; VIREMIA;

EID: 70350521457     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200939389     Document Type: Article

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