메뉴 건너뛰기




Volumn 53, Issue 5, 2014, Pages 422-431

Genistein inhibits DNA methylation and increases expression of tumor suppressor genes in human breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; DNA; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; GENISTEIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; SERINE PROTEINASE INHIBITOR; STRATIFIN;

EID: 84895922467     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.22154     Document Type: Article
Times cited : (159)

References (43)
  • 1
    • 82455174438 scopus 로고    scopus 로고
    • DNA methylation and soy phytoestrogens: Quantitative study in DU-145 and PC-3 human prostate cancer cell lines
    • Adjakly M, Bosviel R, Rabiau N, Boiteux J-P, Bignon Y-J, Guy L, Bernard-Gallon D. 2011. DNA methylation and soy phytoestrogens: Quantitative study in DU-145 and PC-3 human prostate cancer cell lines. Epigenomics 3:795-803.
    • (2011) Epigenomics , vol.3 , pp. 795-803
    • Adjakly, M.1    Bosviel, R.2    Rabiau, N.3    Boiteux, J.-P.4    Bignon, Y.-J.5    Guy, L.6    Bernard-Gallon, D.7
  • 2
    • 48749117943 scopus 로고    scopus 로고
    • Multi-targeted therapy of cancer by genistein
    • Banerjee S, Li Y, Wang Z, Sarkar FH. 2008. Multi-targeted therapy of cancer by genistein. Cancer Lett 269:226-242.
    • (2008) Cancer Lett , vol.269 , pp. 226-242
    • Banerjee, S.1    Li, Y.2    Wang, Z.3    Sarkar, F.H.4
  • 3
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer-A mechanism for early oncogenic pathway addiction?
    • Baylin SB, Ohm JE. 2006. Epigenetic gene silencing in cancer-A mechanism for early oncogenic pathway addiction? Nat Rev Cancer 6:107-116.
    • (2006) Nat Rev Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 4
    • 84874714195 scopus 로고    scopus 로고
    • Maternal diet supplementation with methyl donors and increased parity affect the incidence of craniofacial defects in the offspring of twisted gastrulation mutant mice
    • Billington CJ, Jr., Schmidt B, Zhang L, Hodges JS, Georgieff MK, Schotta G, Gopalakrishnan R, Petryk A. 2013. Maternal diet supplementation with methyl donors and increased parity affect the incidence of craniofacial defects in the offspring of twisted gastrulation mutant mice. J Nutr 143:332-339.
    • (2013) J Nutr , vol.143 , pp. 332-339
    • Billington Jr., C.J.1    Schmidt, B.2    Zhang, L.3    Hodges, J.S.4    Georgieff, M.K.5    Schotta, G.6    Gopalakrishnan, R.7    Petryk, A.8
  • 5
    • 84860734987 scopus 로고    scopus 로고
    • Can soy phytoestrogens decrease DNA methylation in BRCA1 and BRCA2 oncosuppressor genes in breast cancer?
    • Bosviel R, Dumollard E, Dechelotte P, Bignon YJ, Bernard-Gallon D. 2012. Can soy phytoestrogens decrease DNA methylation in BRCA1 and BRCA2 oncosuppressor genes in breast cancer? OMICS 16:235-244.
    • (2012) OMICS , vol.16 , pp. 235-244
    • Bosviel, R.1    Dumollard, E.2    Dechelotte, P.3    Bignon, Y.J.4    Bernard-Gallon, D.5
  • 6
    • 0037068379 scopus 로고    scopus 로고
    • 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: Mechanistic studies and their implications for cancer therapy
    • Christman JK. 2002. 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: Mechanistic studies and their implications for cancer therapy. Oncogene 21:5483-5495.
    • (2002) Oncogene , vol.21 , pp. 5483-5495
    • Christman, J.K.1
  • 7
    • 0035902801 scopus 로고    scopus 로고
    • Differences between human breast cell lines in susceptibility towards growth inhibition by genistein
    • Dampier K, Hudson EA, Howells LM, Manson MM, Walker RA, Gescher A. 2001. Differences between human breast cell lines in susceptibility towards growth inhibition by genistein. Br J Cancer 85:618-624.
    • (2001) Br J Cancer , vol.85 , pp. 618-624
    • Dampier, K.1    Hudson, E.A.2    Howells, L.M.3    Manson, M.M.4    Walker, R.A.5    Gescher, A.6
  • 8
    • 63449113187 scopus 로고    scopus 로고
    • Epigenetic alterations in the breast: Implications for breast cancer detection, prognosis and treatment
    • Dworkin AM, Huang TH, Toland AE. 2009. Epigenetic alterations in the breast: Implications for breast cancer detection, prognosis and treatment. Semin Cancer Biol 19:165-171.
    • (2009) Semin Cancer Biol , vol.19 , pp. 165-171
    • Dworkin, A.M.1    Huang, T.H.2    Toland, A.E.3
  • 10
    • 33845969839 scopus 로고    scopus 로고
    • Dietary polyphenols may affect DNA methylation
    • Fang M, Chen D, Yang CS. 2007. Dietary polyphenols may affect DNA methylation. J Nutr 137:223S-228S.
    • (2007) J Nutr , vol.137
    • Fang, M.1    Chen, D.2    Yang, C.S.3
  • 11
    • 0345275879 scopus 로고    scopus 로고
    • Tea Polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines
    • Fang MZ, Wang Y, Ai N, Hou Z, Sun Y, Lu H, Welsh W, Yang CS. 2003. Tea Polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res 63:7563-7570.
    • (2003) Cancer Res , vol.63 , pp. 7563-7570
    • Fang, M.Z.1    Wang, Y.2    Ai, N.3    Hou, Z.4    Sun, Y.5    Lu, H.6    Welsh, W.7    Yang, C.S.8
  • 12
    • 26444451123 scopus 로고    scopus 로고
    • Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy
    • Fang MZ, Chen D, Sun Y, Jin Z, Christman JK, Yang CS. 2005. Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy. Clin Cancer Res 11:7033-7041.
    • (2005) Clin Cancer Res , vol.11 , pp. 7033-7041
    • Fang, M.Z.1    Chen, D.2    Sun, Y.3    Jin, Z.4    Christman, J.K.5    Yang, C.S.6
  • 13
    • 84855956247 scopus 로고    scopus 로고
    • Epigenetics and the environment: Emerging patterns and implications
    • Feil R, Fraga MF. 2011. Epigenetics and the environment: Emerging patterns and implications. Nat Rev Genet 13:97-109.
    • (2011) Nat Rev Genet , vol.13 , pp. 97-109
    • Feil, R.1    Fraga, M.F.2
  • 16
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman JG, Baylin SB. 2003. Gene silencing in cancer in association with promoter hypermethylation. New England J Med 349:2042-2054.
    • (2003) New England J Med , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 18
    • 84861212776 scopus 로고    scopus 로고
    • MicroRNA-34a and microRNA-21 play roles in the chemopreventive effects of 3,6-dihydroxyflavone on 1-methyl-1-nitrosourea-induced breast carcinogenesis
    • Hui C, Yujie F, Lijia Y, Long Y, Hongxia X, Yong Z, Jundong Z, Qianyong Z, Mantian M. 2012. MicroRNA-34a and microRNA-21 play roles in the chemopreventive effects of 3, 6-dihydroxyflavone on 1-methyl-1-nitrosourea-induced breast carcinogenesis. Breast Cancer Res 14:R80.
    • (2012) Breast Cancer Res , vol.14
    • Hui, C.1    Yujie, F.2    Lijia, Y.3    Long, Y.4    Hongxia, X.5    Yong, Z.6    Jundong, Z.7    Qianyong, Z.8    Mantian, M.9
  • 19
    • 84872540201 scopus 로고    scopus 로고
    • Flavonoids, flavonoid subclasses and breast cancer risk:A meta-analysis of epidemiologic studies
    • Hui C, Qi X, Qianyong Z, Xiaoli P, Jundong Z, Mantian M. 2013. Flavonoids, flavonoid subclasses and breast cancer risk:A meta-analysis of epidemiologic studies. PLoS One 8:e54318.
    • (2013) PLoS One , vol.8
    • Hui, C.1    Qi, X.2    Qianyong, Z.3    Xiaoli, P.4    Jundong, Z.5    Mantian, M.6
  • 20
    • 59249103688 scopus 로고    scopus 로고
    • Cancer prevention: Epigenetics steps up to the plate
    • Issa JP. 2008. Cancer prevention: Epigenetics steps up to the plate. Cancer Prev Res (Phila) 1:219-222.
    • (2008) Cancer Prev Res (Phila) , vol.1 , pp. 219-222
    • Issa, J.P.1
  • 22
    • 33947310031 scopus 로고    scopus 로고
    • Environmental epigenomics and disease susceptibility
    • Jirtle RL, Skinner MK. 2007. Environmental epigenomics and disease susceptibility. Nat Rev Genet 8:253-262.
    • (2007) Nat Rev Genet , vol.8 , pp. 253-262
    • Jirtle, R.L.1    Skinner, M.K.2
  • 23
    • 0037068378 scopus 로고    scopus 로고
    • DNA methylation and cancer
    • Jones PA. 2002. DNA methylation and cancer. Oncogene 21:5358-5360.
    • (2002) Oncogene , vol.21 , pp. 5358-5360
    • Jones, P.A.1
  • 25
    • 39749140314 scopus 로고    scopus 로고
    • Modulation of gene methylation by genistein or lycopene in breast cancer cells
    • King-Batoon A, Leszczynska JM, Klein CB. 2008. Modulation of gene methylation by genistein or lycopene in breast cancer cells. Environ Mol Mutagen 49:36-45.
    • (2008) Environ Mol Mutagen , vol.49 , pp. 36-45
    • King-Batoon, A.1    Leszczynska, J.M.2    Klein, C.B.3
  • 26
    • 77955621544 scopus 로고    scopus 로고
    • Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components
    • Li Y, Tollefsbol TO. 2010. Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components. Curr Med Chem 17:2141-2151.
    • (2010) Curr Med Chem , vol.17 , pp. 2141-2151
    • Li, Y.1    Tollefsbol, T.O.2
  • 27
    • 67449084948 scopus 로고    scopus 로고
    • Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms
    • Li Y, Liu L, Andrews LG, Tollefsbol TO. 2009. Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms. Int J Cancer 125:286-296.
    • (2009) Int J Cancer , vol.125 , pp. 286-296
    • Li, Y.1    Liu, L.2    Andrews, L.G.3    Tollefsbol, T.O.4
  • 28
    • 78049429911 scopus 로고    scopus 로고
    • Cancer chemoprevention by dietary polyphenols: Promising role for epigenetics
    • Link A, Balaguer F, Goel A. 2010. Cancer chemoprevention by dietary polyphenols: Promising role for epigenetics. Biochem Pharmacol 80:1771-1792.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1771-1792
    • Link, A.1    Balaguer, F.2    Goel, A.3
  • 29
    • 61549112191 scopus 로고    scopus 로고
    • Epigenomics and breast cancer
    • Lo PK, Sukumar S. 2008. Epigenomics and breast cancer. Pharmacogenomics 9:1879-1902.
    • (2008) Pharmacogenomics , vol.9 , pp. 1879-1902
    • Lo, P.K.1    Sukumar, S.2
  • 30
    • 84872285699 scopus 로고    scopus 로고
    • Folic acid enforces DNA methylation-mediated transcriptional silencing of |PTEN, APC and RARbeta2 tumour suppressor genes in breast cancer
    • Lubecka-Pietruszewska K, Kaufman-Szymczyk A, Stefanska B, Fabianowska-Majewska K. 2013. Folic acid enforces DNA methylation-mediated transcriptional silencing of |PTEN, APC and RARbeta2 tumour suppressor genes in breast cancer. Biochem Biophys Res Commun 430:623-628.
    • (2013) Biochem Biophys Res Commun , vol.430 , pp. 623-628
    • Lubecka-Pietruszewska, K.1    Kaufman-Szymczyk, A.2    Stefanska, B.3    Fabianowska-Majewska, K.4
  • 31
    • 74549216395 scopus 로고    scopus 로고
    • Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-cell translocation gene 3 in prostate cancer
    • Majid S, Dar AA, Shahryari V, Hirata H, Ahmad A, Saini S, Tanaka Y, Dahiya AV, Dahiya R. 2010. Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-cell translocation gene 3 in prostate cancer. Cancer 116:66-76.
    • (2010) Cancer , vol.116 , pp. 66-76
    • Majid, S.1    Dar, A.A.2    Shahryari, V.3    Hirata, H.4    Ahmad, A.5    Saini, S.6    Tanaka, Y.7    Dahiya, A.V.8    Dahiya, R.9
  • 32
    • 79955983980 scopus 로고    scopus 로고
    • Advances in the computational development of DNA methyltransferase inhibitors
    • Medina-Franco JL, Caulfield T. 2011. Advances in the computational development of DNA methyltransferase inhibitors. Drug Discov Today 16:418-425.
    • (2011) Drug Discov Today , vol.16 , pp. 418-425
    • Medina-Franco, J.L.1    Caulfield, T.2
  • 33
    • 77955352742 scopus 로고    scopus 로고
    • Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines
    • Meeran SM, Patel SN, Tollefsbol TO. 2010. Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines. PLoS One 5:e11457.
    • (2010) PLoS One , vol.5
    • Meeran, S.M.1    Patel, S.N.2    Tollefsbol, T.O.3
  • 35
    • 71549153495 scopus 로고    scopus 로고
    • Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways
    • Ouyang G, Yao L, Ruan K, Song G, Mao Y, Bao S. 2009. Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways. Cell Biol Int 33:1237-1244.
    • (2009) Cell Biol Int , vol.33 , pp. 1237-1244
    • Ouyang, G.1    Yao, L.2    Ruan, K.3    Song, G.4    Mao, Y.5    Bao, S.6
  • 36
    • 36048947234 scopus 로고    scopus 로고
    • Breast cancer: Origins and evolution
    • Polyak K. 2007. Breast cancer: Origins and evolution. J Clin Invest 117:3155-3163.
    • (2007) J Clin Invest , vol.117 , pp. 3155-3163
    • Polyak, K.1
  • 40
  • 41
    • 0043093697 scopus 로고    scopus 로고
    • Transposable elements: Targets for early nutritional effects on epigenetic gene regulation
    • Waterland RA, Jirtle RL. 2003. Transposable elements: Targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol 23:5293-5300.
    • (2003) Mol Cell Biol , vol.23 , pp. 5293-5300
    • Waterland, R.A.1    Jirtle, R.L.2
  • 42
    • 77349089525 scopus 로고    scopus 로고
    • Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation
    • Wu Y, Alvarez M, Slamon DJ, Koeffler P, Vadgama JV. 2010. Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation. BMC Cancer 10:32.
    • (2010) BMC Cancer , vol.10 , pp. 32
    • Wu, Y.1    Alvarez, M.2    Slamon, D.J.3    Koeffler, P.4    Vadgama, J.V.5
  • 43
    • 84873260311 scopus 로고    scopus 로고
    • Isoflavone consumption and risk of breast cancer: A dose-response meta-analysis of observational studies
    • Xie Q, Chen ML, Qin Y, Zhang QY, Xu HX, Zhou Y, Mi MT, Zhu JD. 2013. Isoflavone consumption and risk of breast cancer: A dose-response meta-analysis of observational studies. Asia Pac J Clin Nutr 22:118-127.
    • (2013) Asia Pac J Clin Nutr , vol.22 , pp. 118-127
    • Xie, Q.1    Chen, M.L.2    Qin, Y.3    Zhang, Q.Y.4    Xu, H.X.5    Zhou, Y.6    Mi, M.T.7    Zhu, J.D.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.