High frequency of hypermethylation at the 14-3-3 σ locus leads to gene silencing in breast cancer

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 11, 2000, Pages 6049-6054

  Ferguson, Anne T ^a,e   Evron, Ella ^a   Umbricht, Christopher B ^a   Pandita, Tej K ^b   Chan, Timothy A ^a   Hermeking, Heiko ^a   Marks, Jeffrey R ^c   Lambers, Anouk R ^c   Futreal, P Andrew ^c   Stampfer, Martha R ^d   Sukumar, Saraswati ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b Columbia University ^*  (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^e Calydon Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; MESSENGER RNA;

ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CELL CYCLE G2 PHASE; CELL STRAIN MCF 7; CHROMOSOME BREAKAGE; CONTROLLED STUDY; CPG ISLAND; DNA DAMAGE; GAMMA IRRADIATION; GENE EXPRESSION; GENE FREQUENCY; GENE LOCUS; GENE SILENCING; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; MALIGNANT TRANSFORMATION; METHYLATION; PRIORITY JOURNAL;

14-3-3 PROTEINS; AZACITIDINE; BREAST; BREAST NEOPLASMS; CELL CYCLE PROTEINS; CELL LINE; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, NEOPLASTIC; CPG ISLANDS; DNA METHYLATION; DNA REPAIR; EPITHELIAL CELLS; FEMALE; G2 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; NEOPLASM PROTEINS; PROTEIN BIOSYNTHESIS; PROTEINS; RADIATION TOLERANCE; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; RNA, NEOPLASM; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED; TYROSINE 3-MONOOXYGENASE;

EID: 12944275670     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.100566997     Document Type: Article

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