Neuropsychological functioning in youth with obsessive compulsive disorder: An examination of executive function and memory impairment

Psychiatry Research

Volumn 216, Issue 1, 2014, Pages 108-115

  Lewin, Adam B ^a   Larson, Michael J ^b   Park, Jennifer M ^a   McGuire, Joseph F ^a   Murphy, Tanya K ^a   Storch, Eric A ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b BRIGHAM YOUNG UNIVERSITY   (United States)

Author keywords

Children; Executive functioning; Memory; Neuropsychological impairment; Obsessive compulsive disorder (OCD)

Indexed keywords

ANTIDEPRESSANT AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; CENTRAL STIMULANT AGENT; NEUROLEPTIC AGENT;

ADOLESCENT; ANXIETY DISORDER; ARTICLE; ATTENTION DEFICIT DISORDER; CHILD; CHILDREN YALE BROWN OBSESSIVE COMPULSIVE SCALE; COMORBIDITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DEPRESSION; DISEASE ASSOCIATION; DISEASE SEVERITY; EXECUTIVE FUNCTION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEMORY DISORDER; NEUROPSYCHOLOGICAL TEST; OBSESSIVE COMPULSIVE DISORDER; PRIORITY JOURNAL; TIC; CASE CONTROL STUDY; COMPLICATION; MEMORY; OBSESSIVE-COMPULSIVE DISORDER; PSYCHOLOGY; SEVERITY OF ILLNESS INDEX;

ADOLESCENT; ANTIPSYCHOTIC AGENTS; CASE-CONTROL STUDIES; CHILD; EXECUTIVE FUNCTION; FEMALE; HUMANS; MALE; MEMORY; NEUROPSYCHOLOGICAL TESTS; OBSESSIVE-COMPULSIVE DISORDER; SEVERITY OF ILLNESS INDEX;

EID: 84895862303     PISSN: 01651781     EISSN: 18727123     Source Type: Journal    
DOI: 10.1016/j.psychres.2014.01.014     Document Type: Article

References (60)

1. AACAP Practice parameter for the assessment and treatment of children and adolescents with obsessive-compulsive disorder. Journal of the American Acadamy of Child and Adolescent Psychiatry 2012, 51:98-113.
2. Abramovitch A., Abramowitz J.S., Mittelman A. The neuropsychology of adult obsessive-compulsive disorder: a meta-analysis. Clinical Psychology Review 2013, 33:1163-1171.
3. Abramovitch A., Dar R., Hermesh H., Schweiger A. Comparative neuropsychology of adult obsessive-compulsive disorder and attention deficit/hyperactivity disorder: implications for a novel executive overload model of OCD. Journal of Neuropsychology 2012, 6:161-191.
4. Andres S., Boget T., Lazaro L., Penades R., Morer A., Salamero M., Castro-Fornieles J. Neuropsychological performance in children and adolescents with obsessive-compulsive disorder and influence of clinical variables. Biological Psychiatry 2007, 61:946-951.
5. Andres S., Lazaro L., Salamero M., Boget T., Penades R., Castro-Fornieles J. Changes in cognitive dysfunction in children and adolescents with obsessive-compulsive disorder after treatment. Journal of Psychiatry Research 2008, 42:507-514.
6. Basso M.R., Lowery N., Ghormley C., Combs D., Purdie R., Neel J., Davis M., Bornstein R. Comorbid anxiety corresponds with neuropsychological dysfunction in unipolar depression. Cognitive Neuropsychiatry 2007, 12:437-456.
7. Baxter L.R., Schwartz J.M., Bergman K.S., Szuba M.P., Guze B.H., Mazziotta J.C., Alazraki A., Selin C.E., Ferng H.K., Munford P., et al. Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive-compulsive disorder. Archives of General Psychiatry 1992, 49:681-689.
8. Bedard M.J., Joyal C.C., Godbout L., Chantal S. Executive functions and the obsessive-compulsive disorder: on the importance of subclinical symptoms and other concomitant factors. Archives of Clinical Neuropsychology 2009, 24:585-598.
9. Beers S.R., Rosenberg D.R., Dick E.L., Williams T., O'Hearn K.M., Birmaher B., Ryan C.M. Neuropsychological study of frontal lobe function in psychotropic-naive children with obsessive-compulsive disorder. The American Journal of Psychiatry 1999, 156:777-779.
10. Bloch M.H., Sukhodolsky D.G., Dombrowski P.A., Panza K.E., Craiglow B.G., Landeros-Weisenberger A., Leckman J.F., Peterson B.S., Schultz R.T. Poor fine-motor and visuospatial skills predict persistence of pediatric-onset obsessive-compulsive disorder into adulthood. Jounral of Child Psychology and Psychiatry 2011, 52:974-983.
11. de Visser S.J., van der Post J., Pieters M.S., Cohen A.F., van Gerven J.M. Biomarkers for the effects of antipsychotic drugs in healthy volunteers. British Journal of Clinical Pharmacology 2001, 51:119-132.
12. Delis D.C., Kaplan E., Kramer J.H. Delis-Kaplan Executive Function System (D-KEFS) Technical Manual 2001, The Psychological Corporation, San Antonio, TX.
13. Delis D.C., Kramer J.H., Kaplan E., Ober B.A. California Verbal Learning Test - Children's Version Manual 1994, The Psychological Corporation, San Antonio, TX.
14. Flessner C.A., Allgair A., Garcia A., Freeman J., Sapyta J., Franklin M.E., Foa E., March J. The impact of neuropsychological functioning on treatment outcome in pediatric obsessive-compulsive disorder. Depression and Anxiety 2010, 27:365-371.
15. Fontenelle L.F., Mendlowicz M.V., Versiani M. Patients with obsessive-compulsive disorder (OCD) displayed cognitive deficits consistent with a dysfunction of the dorsolateral-striatal circuit. Psychological Medicine 2004, 34:1367-1368.
16. Gale S.D., Hopkins R.O. Effects of hypoxia on the brain: neuroimaging and neuropsychological findings following carbon monoxide poisoning and obstructive sleep apnea. Journal of the International Neuropsychological Society 2004, 10:60-71.
17. Gilbert D.L., Bansal A.S., Sethuraman G., Sallee F.R., Zhang J., Lipps T., Wassermann E.M. Association of cortical disinhibition with tic, ADHD, and OCD severity in Tourette syndrome. Movement Disorders Journal 2004, 19:416-425.
18. Gottesman, Gould T.D. The endophenotype concept in psychiatry: etymology and strategic intentions. The American Journal of Psychiatry 2003, 160:636-645.
19. Greisberg S., McKay D. Neuropsychology of obsessive-compulsive disorder: a review and treatment implications. Clinical Psychology Review 2003, 23:95-117.
20. Guy W. Clinical Global Impressions, ECDEU Assessment Manual for Psychopharmacology 1976, 218-222. National Institute for Mental Health, Rockville, MD.
21. Head D., Bolton D., Hymas N. Deficit in cognitive shifting ability in patients with obsessive-compulsive disorder. Biological Psychiatry 1989, 25:929-937.
22. Henin A., Mick E., Biederman J., Fried R., Hirshfeld-Becker D.R., Micco J.A., Miller K.G., Rycyna C.C., Wozniak J. Is psychopharmacologic treatment associated with neuropsychological deficits in bipolar youth?. Journal of Clinical Psychiatry 2009, 70:1178-1185.
23. Hollander E., Bienstock C.A., Koran L.M., Pallanti S., Marazziti D., Rasmussen S.A., Ravizza L., Benkelfat C., Saxena S., Greenberg B.D., Sasson Y., Zohar J. Refractory obsessive-compulsive disorder: state-of-the-art treatment. Journal of Clinical Psychiatry 2002, 63(Suppl 6):S20-S29.
24. Kim M.S., Park S.J., Shin M.S., Kwon J.S. Neuropsychological profile in patients with obsessive-compulsive disorder over a period of 4-month treatment. Journal of Psychiatry Research 2002, 36:257-265.
25. Kuelz A.K., Hohagen F., Voderholzer U. Neuropsychological performance in obsessive-compulsive disorder: a critical review. Biological Psychology 2004, 65:185-236.
26. Larson M.J., Weaver L.K., Hopkins R.O. Cognitive sequelae in acute respiratory distress syndrome patients with and without recall of the intensive care unit. Journal of International Neuropsychological Society 2007, 13:595-605.
27. Lewin A.B., Piacentini J. Obsessive-compulsive disorder in children. Kaplan and Sadock's Comprehensive Textbook of Psychiatry 2009, 3671-3678. Lippincott, Williams & Wilkins, Philadelphia. 9th ed. B.J. Sadock, V.A. Sadock, P. Ruiz (Eds.).
28. Lewin A.B., Piacentini J. Evidence-based assessment of child obsessive compulsive disorder: recommendations for clinical practice and treatment research. Child Youth Care Forum 2010, 39:73-89.
29. Lewin, A.B., Piacentini, J., De Nadai, A.S., Jones, A.M., Peris, T.S., Geffken, G.R., Geller, D.A., Nadeau, J.M., Murphy, T.K., Storch, E.A., 2014. Defining clinical severity in pediatric obsessive compulsive disorder. Psychological Assessment in press. http://dx.doi.org/10.1037/a0035174.
30. Lewin A.B., Storch E.A., Mutch P.J., Murphy T.K. Neurocognitive functioning in youth with pediatric autoimmune neuropsychiatric disorders associated with streptococcus. Journal of Neuropsychiatry and Clinical Neurosciences 2011, 23:391-398.
31. Markarian Y., Larson M.J., Aldea M.A., Baldwin S.A., Good D., Berkeljon A., Murphy T.K., Storch E.A., McKay D. Multiple pathways to functional impairment in obsessive-compulsive disorder. Clinical Psychology Review 2010, 30:78-88.
32. Mataix-Cols D., Alonso P., Pifarre J., Menchon J.M., Vallejo J. Neuropsychological performance in medicated vs. unmedicated patients with obsessive-compulsive disorder. Psychiatry Research 2002, 109:255-264.
33. Meyers J.E., Meyers K.R. Rey Complex Figure Test and Recognition Trial: Professional Manual 1995, Psychological Assessent Resources, Odessa, FL.
34. Moritz S., Birkner C., Kloss M., Jacobsen D., Fricke S., Bothern A., Hand I. Impact of comorbid depressive symptoms on neuropsychological performance in obsessive-compulsive disorder. Journal of Abnormal Psychology 2001, 110:653-657.
35. Moritz S., Birkner C., Kloss M., Jahn H., Hand I., Haasen C., Krausz M. Executive functioning in obsessive-compulsive disorder, unipolar depression, and schizophrenia. Archives of Clinical Neuropsychology 2002, 17:477-483.
36. Nielen M.M., Den Boer J.A. Neuropsychological performance of OCD patients before and after treatment with fluoxetine: evidence for persistent cognitive deficits. Psychological Medicine 2003, 33:917-925.
37. Olley A., Malhi G., Sachdev P. Memory and executive functioning in obsessive-compulsive disorder: a selective review. Journal of Affective Disorders 2007, 104:15-23.
38. Ornstein T.J., Arnold P., Manassis K., Mendlowitz S., Schachar R. Neuropsychological performance in childhood OCD: a preliminary study. Depression and Anxiety 2010, 27:372-380.
39. Osterrieth P.A. Le test de copie d'une figure complexe. Contribution a l'etude de la perception et de lat memoire. Archives de Psychologie 1944, 30:206-353.
40. Penades R., Catalan R., Andres S., Salamero M., Gasto C. Executive function and nonverbal memory in obsessive-compulsive disorder. Psychiatry Research 2005, 133:81-90.
41. Purcell R., Maruff P., Kyrios M., Pantelis C. Cognitive deficits in obsessive-compulsive disorder on tests of frontal-striatal function. Biological Psychiatry 1998, 43:348-357.
42. Purcell R., Maruff P., Kyrios M., Pantelis C. Neuropsychological deficits in obsessive-compulsive disorder: a comparison with unipolar depression, panic disorder, and normal controls. Archives of General Psychiatry 1998, 55:415-423.
43. Rao N.P., Reddy Y.C., Kumar K.J., Kandavel T., Chandrashekar C.R. Are neuropsychological deficits trait markers in OCD?. Progress in Neuro-Psychopharmacology Biological Psychiatry 2008, 32:1574-1579.
44. Rey A. L'examen psychologique dans les cas d'encephalopathie traumatique. Archives de Psychologie 1941, 28:286-340.
45. Roh K.S., Shin M.S., Kim M.S., Ha T.H., Shin Y.W., Lee K.J., Kwon J.S. Persistent cognitive dysfunction in patients with obsessive-compulsive disorder: a naturalistic study. Psychiatry and Clinical Neurosciences 2005, 59:539-545.
46. Rubia K., Cubillo A., Smith A.B., Woolley J., Heyman I., Brammer M.J. Disorder-specific dysfunction in right inferior prefrontal cortex during two inhibition tasks in boys with attention-deficit hyperactivity disorder compared to boys with obsessive-compulsive disorder. Human Brain Mapping 2010, 31:287-299.
47. Rubia K., Cubillo A., Woolley J., Brammer M.J., Smith A. Disorder-specific dysfunctions in patients with attention-deficit/hyperactivity disorder compared to patients with obsessive-compulsive disorder during interference inhibition and attention allocation. Human Brain Mapping 2011, 32:601-611.
48. Savage C.R., Deckersbach T., Wilhelm S., Rauch S.L., Baer L., Reid T., Jenike M.A. Strategic processing and episodic memory impairment in obsessive compulsive disorder. Neuropsychology 2000, 14:141-151.
49. Savage C.R., Rauch S.L. Cognitive deficits in obsessive-compulsive disorder. The American Journal of Psychiatry 2000, 157:1182-1183.
50. Saxena S., Rauch S.L. Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder. Psychiatric Clinics of North America 2000, 23:563-586.
51. Scahill L., Riddle M.A., McSwiggin-Hardin M., Ort S.I. Children's yale-brown obsessive compulsive scale: reliability and validity. Journal of the American Academy of Child & Adolescent Psychiatry 1997, 36:844-852.
52. Schultz R.T., Evans D.W., Wolff M. Neuropsychological models of childhood obsessive-compulsive disorder. Child and Adolescent Psychiatric Clinics of North America 1999, 8:513-531.
53. Shaffer D., Gould M.S., Brasic J., Ambrosini P., Fisher P., Bird H., Aluwahlia S. A children's global assessment scale (CGAS). Archives of General Psychiatry 1983, 40:1228-1231.
54. Sheslow D., Adams W. Wide Range Assessment of Memory and Learning - Second Edition: Administration and Technical Manual 2003, Wide Range, Inc., Wilmington, DE.
55. Shin M.S., Choi H., Kim H., Hwang J.W., Kim B.N., Cho S.C. A study of neuropsychological deficit in children with obsessive-compulsive disorder. European Psychiatry 2008, 23:512-520.
56. Shin N.Y., Kang D.H., Choi J.S., Jun M.H., Jang J.H., Kwon J.S. Do organizational strategies mediate nonverbal memory impairment in drug-naïve patients with obsessive-compulsive disorder?. Neuropsychology 2010, 24:527-533.
57. Silverman W.K., Albano A.M. The Anxiety Disorders Interview Schedule for DSM-IV-Child and Parent Versions 1996, Oxford University Press, London.
58. Sukhodolsky D.G., Landeros-Weisenberger A., Scahill L., Leckman J.F., Schultz R.T. Neuropsychological functioning in children with Tourette syndrome with and without attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry 2010, 49:1155-1164.
59. Vloet T.D., Marx I., Kahraman-Lanzerath B., Zepf F.D., Herpertz-Dahlmann B., Konrad K. Neurocognitive performance in children with ADHD and OCD. Journal of Abnormal Child Psychology 2010, 38:961-969.
60. Whiteside S.P. Adapting the Sheehan disability scale to assess child and parent impairment related to childhood anxiety disorders. Journal of Clinical Child and Adolescent Psychology 2009, 38:721-730.