A study of neuropsychological deficit in children with obsessive-compulsive disorder

European Psychiatry

Volumn 23, Issue 7, 2008, Pages 512-520

  Shin, Min Sup ^a   Choi, Hyunjung ^a   Kim, Hana ^a   Hwang, Jun Won ^a   Kim, Boong Nyun ^a   Cho, Soo Churl ^a  

^a Seoul National University Children's Hospital   (South Korea)

Author keywords

Childhood OCD; Executive function; Neuropsychological deficit

Indexed keywords

ADOLESCENT; ARTICLE; ATTENTION DEFICIT DISORDER; COGNITION; CONTROLLED STUDY; DEPRESSION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROPSYCHOLOGICAL TEST; OBSESSIVE COMPULSIVE DISORDER; PERCEPTION; PRESCHOOL CHILD; PRIORITY JOURNAL; TIC; UNIVERSITY HOSPITAL; VERBAL BEHAVIOR;

ADOLESCENT; ADULT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CHILD; COGNITION DISORDERS; COMORBIDITY; DEPRESSIVE DISORDER; FEMALE; HUMANS; MALE; OBSESSIVE-COMPULSIVE DISORDER; PREVALENCE; SEVERITY OF ILLNESS INDEX; TIC DISORDERS; WECHSLER SCALES;

EID: 53249113706     PISSN: 09249338     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eurpsy.2008.03.010     Document Type: Article

References (83)

1. Abbruzzese M., Ferri S., and Scarone S. The selective breakdown of frontal functions in patients with obsessive-compulsive disorder and in patients with schizophrenia: a double dissociation experimental finding. Neuropsychologia 35 (1997) 907-912
2. Abbruzzese M., Ferri S., and Scarone S. Wisconsin Card Sorting Test performance in obsessive-compulsive disorder: no evidence for involvement of dorsolateral prefrontal cortex. Psychiatr Res 58 (1995) 37-43
3. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. (1994), APA, Washington DC
4. Andres S., Boget T., Lazaro L., Penades R., Morer A., Salamero M., et al. Neuropsychological performance in children and adolescents with obsessive-compulsive disorder and influence of clinical variables. Biol Psychiatry 61 8 (2007) 946-951
5. Bannon S., Gonsalvez C.J., Croft R.J., and Boyce P.M. Executive functions in obsessive-compulsive disorder: state or trait deficits?. Aust N Z J Psychiatry 40 11-12 (2006) 1031-1038
6. Basso M.R., Bornstein R.A., Carona F., and Morton R. Depression accounts for executive function deficits in obsessive-compulsive disorder. Neuropsychiatry Neuropsychol Behav Neurol 14 (2001) 241-245
7. Baxter Jr. L.R., Schwartz J.M., Mazziotta J.C., Phelps M.E., Pahl J.J., Guze B.H., et al. Cerebral glucose metabolic rates in non-depressed patients with obsessive-compulsive disorder. Am J Psychiatry 145 (1988) 1560-1563
8. Beers S., Rosenberg D., Dick E., Williams T., O'Hearn K.M., Birmaher B., et al. Neuropsychological study of frontal lobe function in psychotropic naïve children with obsessive-compulsive disorder. Am J Psychiatry 156 (1999) 777-779
9. Behar D., Rapoport J.L., Berg C.F., Denckla M.B., Mann L., Cox C., et al. Computerized tomography and neuropsychological test measures in adolescents with obsessive-compulsive disorder. Am J Psychiatry 141 (1984) 363-369
10. Berstein J.H., and Waber D.P. Developmental scoring system for the Rey-Osterreith Complex Figure Manual (1994), PAR, Lutz, FL
11. Boone J.A., and Philpott L. Neuropsychological characteristics of nondepressed adults with obsessive-compulsive disorder. Neuropsychiatry Neuropsychol Behav Neurol 4 (1991) 96-109
12. Cavedini P., Ferri S., Scarone S., and Bellodi L. Frontal lobe dysfunction in obsessive-compulsive disorder and major depression. Psychiatry Res 78 (1998) 21-28
13. Chamberlain S.R., Fineberg N.A., Blackwell A.D., Robbins T.W., and Sahakian B.J. Motor inhibition and cognitive flexibility in obsessive-compulsive disorder and trichotillomania. Am J Psychiatry 163 (2006) 1282-1284
14. Choi J.S., Kang D.H., Kim J.J., Ha T.H., Lee J.M., Youn T., et al. Left anterior subregion of orbitofrontal cortex volume reduction and impaired organizational strategies in obsessive-compulsive disorder. J Psychiatr Res 38 (2004) 193-199
15. Christensen K.J., WonKim S., Dysken W., and Hoover K.M. Neuropsychological performance in obsessive compulsive disorder. Biol Psychiatry 31 (1992) 4-18
16. Constans J.I., Foa E.B., Franklin M.E., and Mathews A. Memory for actual and imagined events in OC checkers. Behav Res Ther 33 (1995) 665-671
17. Cottraux J., and Gerard D. Neuroimaging and neuroanatomical issues in obsessive-compulsive disorder. In: Swinson R.P., Antony M.M., Rachman S., and Richter M.A. (Eds). Obsessive-Compulsive Disorder: Theory, research, and treatment (1998), Guilford, New York, NP 154-180
18. Delis D.C., Kramer J.H., Kaplan E., and Ober B.A. California Verbal Learning Test: adult version manual (1987), The Psychological Corporation, San Antonio, TX
19. Fenger M.M., Gade A., Adams K.H., Hansen E.S., Bolwig T.G., and Knudsen G.M. Cognitive deficits in obsessive-compulsive disorder on tests of frontal lobe functions. Nor J Psychiatry 59 (2005) 39-44
20. Gross-Isseroff, Sasson Y., Voet H., Luca-Haimovici K., Kandel-Sussman H., Hendler T., et al. Alternation learning in obsessive-compulsive disorder. Biol Psychiatry 39 (1996) 733-738
21. Hanna G., Fischer D.J., Chadha K., Himle J., and Van Etten M. Familial and sporadic subtypes of early-onset obsessive-compulsive disorder. Biol Psychiatry 57 (2005) 895-900
22. Harvey N.S. Impaired cognitive set shifting in obsessive-compulsive neurosis. IRCS Med Sci 14 (1986) 936-937
23. Head D., Bolton D., and Hymas N. Deficit in neurocognitive shifting ability in patients with obsessive-compulsive disorders. Biol Psychiatry 25 (1989) 929-937
24. Heaton R.K., Chelune G.J., Talley J.L., Kay G.G., and Curtiss G. Wisconsin card sorting test manual revised and expanded (1993), PAR
25. Henin A., Savage C.R., Rauch S.L., Deckersbach T., Wilhelm S., Baer L., et al. Is age at symptom onset associated with severity of memory impairment in adults with obsessive-compulsive disorder?. Am J Psychiatry 158 (2001) 137-139
26. Hong K.E. Korean textbook of child psychiatry (2005), JMC, Seoul
27. Horton A.M. Some suggestions regarding the clinical interpretation of the Trail Making Test. Clin Neuropsychol 1 (1979) 20-23
28. Hymas N., Lees A., Bolton D., Epps K., and Head D. The neurology of obsessional slowness. Brain 114 (1991) 2203-2233
29. Insel T.R., Donnelly E.F., Lalakea M.L., Alterman I.S., and Murphy D.L. Neurological and neuropsychological studies of patients with obsessive-compulsive disorder. Biol Psychiatry 18 (1983) 741-751
30. Kim B.N., Lee J.S., Shin M.S., Cho S.C., and Lee D.S. Regional cerebral perfusion abnormalities in attention deficit hyperactivity disorder. Eur Arch Clin Neurosci 252 (2002) 219-225
31. Korean Educational Development Institute. Basic Learning Skill Test (1989), KEDI, Seoul
32. Korean Educational Development Institute. Korean Educational Development Institute-Wechsler Intelligence Scale for Children (1991), KEDI, Seoul
33. Kuelz A.K., Hohagen F., and Voderholzer U. Neuropsychological performance in obsessive-compulsive disorder: a critical review. Biol Psychol 65 3 (2004) 185-236
34. Lawrence N.S., Wooderson S., Mataix-Cols D., David R., Speckens A., and Phillips M.L. Decision making and set shifting impairments are associated with distinct symptom dimensions in obsessive-compulsive disorder. Neuropsychology 20 (2006) 409-419
35. Leckman J.F., Pauls D.L., Zhang H., Rosario-Campos M.C., Katsovich L., Kidd K.K., et al. Obsessive compulsive symptom dimensions in affected sibling pairs diagnosed with Gilles de la Tourette syndrome. Am J Med Genet 116B (2003) 60-68
36. Lee J.S., Shin M.S., and Hong K.E. Development of the Korean form of Leyton obsessional inventory-child version (LOI-CV). Kor J Child Adolesc Psychiatry 5 (1994) 162-171
37. Loose R., Kaufmann C., Tucha O., Auer D.P., and Lange K.W. Neural networks of response shifting: influence of task speed and stimulus material. Brain Res 1090 1 (2006) 146-155
38. Lucey J.V., Costa D.C., Busatto G., Pilowsky L.S., Marks I.M., Ell P.J., et al. Caudate regional cerebral blood flow in obsessive-compulsive disorder, panic disorder and healthy controls on single photon emission computerised tomography. Psychiatry Res 74 (1997) 25-33
39. Martin A., Wiggs C.L., Altemus M., Rubenstein C., and Murphy D.L. Working memory as assessed by subject-ordered tasks in patients with obsessive-compulsive disorder. J Clin Exp Neuropsychol 17 (1995) 786-792
40. Martinot J.L., Allilaire J.F., Mazoyer B.M., Hantouche E., Huret J.D., Legaut-Demare F., et al. Obsessive-compulsive disorder: a clinical, neuropsychological and positron emission tomography study. Acta Psychiatr Scand 82 (1990) 233-242
41. Mataix-Cols D., Alonso P., Pifarré J., Menchón J.M., and Vallejo J. Neuropsychological performance in medicated vs. unmedicated patients with obsessive-compulsive disorder. Psychiatry Res 109 3 (2002) 255-264
42. Mataix-Cols D., Junqué C., Sànchez-Turet M., Vallejo J., Verger K., and Barrios M. Neuropsychological functioning in a subclinical obsessive-compulsive sample. Biol Psychiatry 45 (1999) 898-904
43. Mataix-Cols D., Rosario-Campos M., and Leckman J.F. A multidimensional model of obsessive-compulsive disorder. Am J Psychiatry 162 (2005) 228-238
44. McKay D. Neuropsychology of obsessive-compulsive disorder: a review and treatment implications. Clin Psychol Rev 23 (2003) 95-117
45. Meyers J.E., and Meyers K.R. Rey Complex Figure Test and recognition trial: professional manual (1995), Psychological Assessment Resources, Odessa, FL
46. Meyers J.E., and Meyers K.R. Rey Complex Figure Test under four different administration procedures. Clin Neuropsychol 9 (1995) 63-67
47. Moritz S., Birkner C., Kloss M., Jacobsen D., Fricke S., Bothern A., et al. Impact of comorbid depressive symptoms on neuropsychological performance in obsessive-compulsive disorder. J Abnorm Psychol 110 (2001) 653-657
48. Moritz S., Birkner C., Kloss M., Jahn H., Hand I., Haasen C., et al. Executive functioning in obsessive-compulsive disorder, unipolar depression and schizophrenia. Arch Clin Neuropsychology 17 (2002) 477-483
49. Okasha A., Rafaat M., Mahallawy N., El Nahas G., El Dawla A.S., Sayed M., et al. Cognitive dysfunction in obsessive-compulsive disorder. Acta Psychiatr Scand 101 (2000) 281-285
50. Park H.S., Lee Y.H., Ha T.H., Rho K.S., Shin M.S., and Kwon J.S. Impairment of visual and verbal memory, and mediating effects of organizational strategies on the impaired memory of obsessive-compulsive disorder patients. Korean J Clin Psychol 22 (2003) 725-742
51. Pennington B.F., and Welsh M. Neuropsychology and developmental psychopathology. In: Cicchetti D., and Cohen D.J. (Eds). Developmental psychopathology: theory and method (1995), John Wiley & Sons, New York
52. Petrides M., and Milner B. Deficits on subject-ordered tasks after frontal and temporal lobe lesions in man. Neuropsychologia 20 (1982) 249-262
53. Pujol J., Soriano-Mas C., Alonso P., Cardoner N., Menchon J.M., Deus J., et al. Mapping structural brain alterations in obsessive-compulsive disorder. Arch Gen Psychiatry 61 (2004) 720-730
54. Purcell R., Maruff P., Kyrios M., and Pantelis C. Neuropsychological deficits in obsessive-compulsive disorder: a comparison with unipolar depression, panic disorder, and normal controls. Arch Gen Psychiatry 55 (1998) 415-423
55. Randomsky A., and Rachman S. Memory bias in obsessive-compulsive disorder. Behav Res Ther 37 (1999) 605-618
56. Rapoport J.L. Obsessive-compulsive disorder and basal ganglia dysfunction. Psychol Med 20 (1990) 465-469
57. Rasmussen S.A., and Eisen J.L. Epidemiology of obsessive compulsive disorder. J Clin Psychiatry 53 (1990) 10-14
58. Reitan R.M. An investigation of the validity of Halstead's measures of biological intelligence. Arch Neurol Psychiatry 73 (1955) 28-35
59. Rettew D.C., Swedo S.E., Leonard H.L., Lenane M.C., and Rapoport J. Obsessions and compulsions across time in 79 children and adolescents with obsessive-compulsive disorder. J Am Acad Child Adolesc Psychiatry 31 (1992) 1050-1056
60. Rey A. L'examine psychologique dans les cas d'encephalopathie traumatique. Arch Psychol 28 (1941) 286-340
61. Rubenstein C.S., Peynircioglu Z.F., Chambless D.L., and Pigott T.A. Memory in sub-clinical obsessive-compulsive checkers. Behav Res Ther 31 (1993) 759-765
62. Savage C.R. Neuropsychology of obsessive-compulsive disorder: research findings and treatment implications. In: Jenike M.A., Baer L., and Minichiello W.E. (Eds). Obsessive-compulsive disorders: practical management. 3rd ed. (1998), Mosby, St. Louis 254-275
63. Savage C.R., Baer L., Keuthen N.J., Brown H.D., Rauch S.L., and Jenike M.A. Organizational strategies mediate nonverbal memory impairment in obsessive-compulsive disorder. Biol Psychiatry 45 7 (1999) 905-916
64. Savage C.R., Deckersbach T., Heckers S., Wagner A.D., Schacter D.L., Alpert N.M., et al. Prefrontal regions supporting spontaneous and directed application of verbal learning strategies evidence from PET. Brain 124 1 (2001) 219-231
65. Savage C.R., Deckersbach T., Wilhem S., Rauch S.L., Baer L., Reid T., et al. Strategic processing and episodic memory impairment in obsessive compulsive disorder. Neuropsychology 14 (2000) 1-11
66. Saxena S., Brody A.L., Colgan M., Maidment K.M., Dunkin J.J., Alborzian S., et al. Localized orbitofrontal and subcortical metabolic changes and predictors of response to paroxetine treatment in obsessive-compulsive disorder. Neuropsychopharmacology 21 (1999) 683-693
67. Saxena S., Brody A.L., Schwartz J.M., and Baxter L.R. Neuroimaging and frontal-subcortical circuitry in obsessive-compulsive disorder. Br J Psychiatry Suppl 35 (1998) 26-37
68. Schmidtke K., Schorb A., Winkelmann G., and Hohagen F. Cognitive frontal lobe dysfunction in obsessive-compulsive disorder. Biol Psychiatry 43 (1998) 666-673
69. Seidman L.J., Benedict K.B., Biederman J., Bernstein J.H., Seiverd K., Milberger S., et al. Performance of ADHD children on the Rey-Osterreith Complex Figure: a pilot neuropsychological study. J Child Psychol Psychiatry 36 (1995) 1459-1473
70. Shin M.S., Cho S.Z., Chun S.Y., and Hong K.E.M. A study of the development and standardization of ADHD diagnostic system. Korean J Child Adolesc Psychiatry 11 (2000) 91-99
71. Shin M.S., Kim Y.H., Cho S.C., and Kim B.N. Neuropsychological characteristics of children with attention deficit hyperactivity disorder, learning disorder, tic disorder on Rey-Osterreith Complex Figure. J Child Neurol 18 (2003) 835-844
72. Shin M.S., Park S.J., Kim M.S., Lee Y.H., Ha T.H., and Kwon J.S. Deficit of organizational strategy and visual memory in obsessive-compulsive disorder. Neuropsychology 18 4 (2004) 665-672
73. Somerville J., Tremont G., and Stern R.A. The Boston Qualitative scoring system as a measure of executive functioning in Rey-Osterrieth Complex figure performance. J Clin Exp Neuropsychol 22 (2000) 613-621
74. Spitznagel M.B., and Suhr J.A. Executive function deficits associated with symptoms of schizotypy and obsessive-compulsive disorder. Psychiatry Res 110 (2002) 151-163
75. Swedo S.E., Rapoport J.L., Leonard H., Lenane M., and Cheslow D. Obsessive-compulsive disorder in children and adolescents: clinical phenomenology of 70 consecutive cases. Arch Gen Psychiatry 46 (1989) 335-341
76. Szeszko P.R., Robinson D., Alvir J.M., Bilder R.M., Lencz T., Ashtari M., et al. Orbitalfrontal and amygdala volume reductions in obsessive-compulsive disorder. Arch Gen Psychiatry 56 (1999) 913-919
77. Tallis F., Pratt P., and Jamani N. Obsessive compulsive disorder, checking and non-verbal memory: a neuropsychological investigation. Behav Res Ther 37 (1999) 161-166
78. Taylor E.M. Psychological appraisal of children with cerebral deficits (1959), Harvard Univ. Press, Cambridge, MA
79. Tripp G., Ruam J., and Peace K. Neuropsychological functioning in children with DSM-IV combined typed ADHD. Aust N Z J Psychiatry 36 (2002) 771-779
80. Waber D.P., Bernstein J.H., and Merola J. Remembering the Rey-Osterrieth complex figure: a dual code, cognitive neuropsychological model. Dev Neuropsychol 5 (1989) 1-15
81. Watkins L.H., Sahakian B.J., Robertson M.M., Veale D.M., Rogers R.D., Pickard K.M., et al. Executive function in Tourette's syndrome and obsessive-compulsive disorder. Psychol Med 35 (2005) 571-582
82. Wechsler D. Wechsler Memory Scale. 3rd ed. (1997), The Psychological Corporation, San Antonio, TX
83. Zielinski C.V., Taylor M.A., and Juzwin K.R. Neuropsychological deficits in obsessive-compulsive disorder. Neuropsychiatry Neuropsychol Behav Neurol 4 (1991) 110-126