Neuropsychological deficits in obsessive-compulsive disorder: A comparison with unipolar depression, panic disorder, and normal controls

Archives of General Psychiatry

Volumn 55, Issue 5, 1998, Pages 415-423

  Purcell, Rosemary ^a,b   Maruff, Paul ^b,c   Kyrios, Michael ^a   Pantelis, Christos ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^c SWINBURNE UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COGNITION; COMPUTER ANALYSIS; DEPRESSION; DISEASE ASSOCIATION; INTELLIGENCE QUOTIENT; NEUROPSYCHOLOGICAL TEST; OBSESSION; TREATMENT PLANNING; VISUAL MEMORY;

ADULT; ATTENTION; COGNITION DISORDERS; DEPRESSIVE DISORDER; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; MALE; MEMORY; MOTOR SKILLS; NEUROPSYCHOLOGICAL TESTS; OBSESSIVE-COMPULSIVE DISORDER; PANIC DISORDER; PATTERN RECOGNITION, VISUAL; SET (PSYCHOLOGY); SPACE PERCEPTION;

EID: 0031862339     PISSN: 0003990X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archpsyc.55.5.415     Document Type: Article

References (65)

1. Robinson D, Wu H, Munne RA, Ashtari M. Reduced caudate nucleus volume in obsessive-compulsive disorder. Arch Gen Psychiatry. 1995;52:393-398.
2. Calabrese G, Colombo C, Bonfanti A, Scotti G, Scarone S. Caudate nucleus abnormalities in obsessive-compulsive disorder: measurements of MRI signal intensity. Psychiatry Res. 1993;50:89-92.
3. Scarone S, Colombo C, Livian S, Abbruzzese M, Ronchi P, Locatelli M, Scotti G, Smeraldi E. Increased right caudate nucleus size in obsessive-compulsive disorder: detection with magnetic resonance imaging. Psychiatry Res. 1992;45: 115-121.
4. Luxenberg JS, Swedo SE, Flament MF, Friedland RP. Neuroanatomical abnormalities in obsessive-compulsive disorder detected with quantitative X-ray computed tomography. Am J Psychiatry. 1988;145:1089-1093.
5. Breiter HC, Rauch SL, Kwong KK, Baker JR. Functional magnetic resonance imaging of symptom provocation in obsessive-compulsive disorder. Arch Gen Psychiatry. 1996;53:595-606.
6. Lucey W, Costa DC, Blanes T, Busatto GF, Pilowsky LS, Takei N, Marks IM, Ell PJ, Kerwin RW. Regional cerebral blood flow in obsessive-compulsive disordered patients at rest: differential correlates with obsessive-compulsive and anxious-avoidant dimensions. Br J Psychiatry. 1995;167:629-634.
7. Perani D, Colombo C, Bressi S, Bonfanti A, Grassi F, Scarone S, Bellodi L, Smeraldi E, Fazio F. [F-18] FDG PET study in obsessive-compulsive disorder: a clinical metabolic correlation study after treatment. Br J Psychiatry. 1995;166:244-250.
8. Rubin RT, Ananth J, Villanueva-Meyer J, Trajmar PG, Mena I. Regional 133 xenon cerebral blood flow and cerebral 99mTc-HMPAO uptake in patients with obsessive-compulsive disorder before and during treatment. Biol Psychiatry. 1995; 38:429-437.
9. McGuire PK, Bench CJ, Frith CD, Marks IM, Functional anatomy of obsessivecompulsive phenomena. Br J Psychiatry. 1994;164:459-468.
10. Rauch SL, Jenike MA, Alpert NM, Baer L, Breiter HC, Savage CR, Fischman AJ, Regional cerebral blood flow measured during symptom provocation in obsessive- compulsive disorder using oxygen 15-labeled carbon dioxide and positron emission tomography. Arch Gen Psychiatry. 1994;51:62-70.
11. Baxter LR, Schwartz JM, Mazziotta JC, Pnelps ME. Cerebral glucose metabolic rates in nondepressed patients with obsessive-compulsive disorder. Am J Psychiatry. 1988;145:1560-1563.
12. Swoboda KJ, Jenike MA. Frontal abnormalities in a patient with obsessivecompulsive disorder: the role of structural lesions in obsessive-compulsive behavior. Neurology. 1995;45:2130-2134.
13. Weilburg JB, Mesulam M, Weintraub S, Buonanno F, Jenike M, Stakes JW. Focal striatal abnormalities in a patient with obsessive-compulsive disorder. Arch Neurol. 1989;46:233-235.
14. Veale DM, Sahakian BJ, Owen AM, Marks IM. Specific cognitive deficits in tests sensitive to frontal lobe dysfunction in obsessive-compulsive disorder. Psychol Med. 1996;26:1261-1269.
15. Tien AY, Pearlson GD, Macnlin SR, Bylsma FW. Oculomotor performance in obsessive-compulsive disorder. Am J Psychiatry. 1992;149:641-646.
16. Martinet JL, Allilaire JF, Mazoyer BM, Hantouche E. Obsessive-compulsive disorder: a clinical, neuropsychological and positron emission tomography study. Acta Psychiatr Scand. 1990;82:233-242.
17. Malloy P, Rasmussen S, Braden W, Haier RJ, Topographic evoked potential mapping in obsessive-compulsive disorder: evidence of frontal lobe dysfunction. Psychiatry Res. 1989;28:63-71.
18. Malloy P, Frontal lobe dysfunction in obsessive-compulsive disorder, In: Perecman E, ed. The Frontal Lobes Revisited. New York, NY: IRBN Press; 1987:207- 223.
19. Head D, Bolton D, Hymas N. Deficit in cognitive shifting ability in patients with obsessive-compulsive disorder. Biol Psychiatry. 1989;25:929-937.
20. Christensen KJ, Kim SW, Dysken MW, Hoover KM. Neuropsychological performance in obsessive-compulsive disorder. Biol Psychiatry. 1992;31:4-18.
21. Boone KB, Ananth J, Philpott L, Kaur A. Neuropsychological characteristics of nondepressed adults with obsessive-compulsive disorder. Neuropsychiatry Neuropsychol Behav Neurol. 1991;4:96-109.
22. Zielinski CM, Taylor MA, Juzwin KR. Neuropsychological deficits in obsessivecompulsive disorder. Neuropsychiatry Neuropsychol Behav Neurol. 1991;4:110- 126.
23. Gross-lsseroff R, Sasson Y, Voet H, Hendler T, Luca-Haimovici K, KandeiSussman H, Zohar J. Alternation learning in obsessive-compulsive disorder. Biol Psychiatry. 1996;39:733-738.
24. Martin A, Wiggs CL, Altemus M, Rubenstein C. Working memory as assessed by subject-ordered tasks in patients with obsessive-compulsive disorder. J Clin Exp Neuropsychol. 1995;17:786-792.
25. Galderisi S, Mucci A, Catapano F, Damato AC, Maj M, Neuropsychological slowness in obsessive-compulsive patients: is it confined to tests involving the frontosubcortical systems? Br J Psychiatry. 1995;167:394-398.
26. Elliott R, Sahakian BJ, McKay AP, Herrod JJ, Robbins TW, Paykel ES. Neuropsychological impairments in unipolar depression: the influence of perceived failure on subsequent performance. Psychol Med. 1996;26:975-989.
27. Beats BC, Sahakian BJ, Levy R. Cognitive performance in tests sensitive to frontal lobe dysfunction in elderly depressed. Psychol Med. 1996;26:591-603.
28. Franke P, Maier W, Hardt J, Frieboes R, Lichtermann D, Hain C. Assessment of frontal lobe functioning in schizophrenia and unipolar major depression. Psychopathology. 1993;26:76-84.
29. Abas MA, Sahakian BJ, Levy R. Neuropsychological deficits and CT scan changes in the elderly depressives. Psychol Med. 1990;20:507-520.
30. Cohen LJ, Hollander E, DeCaria CM, Stein CM, Simeon D, Liebowitz MR, Aronowitz BR. Specificity ot neuropsychological impairment in obsessive-compulsive disorder: a comparison with social phobic and normal control subjects. J Neuropsychiatry Clin Neurosci. 1996;8:82-85.
31. Lucas JA, Teich MJ, Bigler ED. Memory functioning in panic disorder: a neuropsychological perspective. J Anxiety Disord. 1991;5:1-20.
32. Asmundson GJG, Stein MB, Larsen DK, Walker JR. Neurocognitive function in panic disorder and social phobia patients. Anxiety. 1994;1:201-207.
33. Morris RG, Evendon JL, Sahakian BJ, Robbins TW. Computer-aided assessment of dementia: comparative studies of neuropsychological deficits in Alzheimertype dementia and Parkinson's disease. In: Stahl SM, Iversen SD, Goodman EC, eds. Cognitive Neurochemistry. New York, NY: Oxford University Press; 1987: 21-36.
34. Robbins TW, James M, Owen AM, Sahakian BJ, McInnes L, Rabbitt P. Cambridge Neuropsychological Test Automated Battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers. Dementia. 1994;5:266- 281,
35. Pantelis C, Barnes TRE, Nelson HE, Tanner S, Weatherley L, Owen AM, Robbins TW, Frontal-striatal cognitive deficits in patients with chronic schizophrenia. Brain. 1997;120:1823-1843.
36. Owen AM, Sahakian BJ, Sample J, Polkey CE, Robbins TW. Visuo-spatial shortterm recognition memory and learning after temporal lobe excisions, frontal lobe excisions or amygdalo-hippocampectomy in man. Neuropsychologia. 1995;33: 1-24.
37. Owen AM, Roberts AC, Polkey CE, Sahakian BJ, Bobbins TW. Extradimensional versus intra-dimensional set shifting performance following frontal lobe excisions, temporal lobe excisions or amygdaio-hippocampectomy in man. Neuropsychologia. 1991;29:993-1006.
38. Owen AM, Downes JJ, Sahakian BJ, Polkey CE, Bobbins TW. Planning and spatial working memory following frontal lobe lesions in man. Neuropsychologia. 1990;28:1021-1034.
39. Robbins TW, James M, Owen AM, Lange KW, Lees AJ, Leigh PN, Marsden CD, Quinn NP, Summers BA. Cognitive deficits in progressive supranuclear palsy, Parkinson's disease and multiple system atrophy in tests sensitive to frontal lobe dysfunction. Neurol Neurosurg Psychiatry. 1994;57:79-88.
40. Owen AM, Roberts AC, Hodges JR, Summers BA, Polkey CE, Robbins TW. Contrasting mechanisms of impaired attentional set-shifting with frontal lobe damage or Parkinson's disease. Brain. 1993;116:1159-1175.
41. Owen AM, James M, Leigh PN, Summers BA, Marsden CD, Quinn NP, Lange KW, Robbins TW. Fronto-striatal cognitive deficits at different stages of Parkinson's disease, Brain. 1992;115:1727-1751.
42. American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington, DC: American Psychiatric Association; 1994.
43. Brown TA, DiNardo PA, Barlow DH. Anxiety Disorders Interview Schedule for DSMIV. New York, NY: Graywind Publications Inc; 1994.
44. Goodman WK, Price LH, Rasmussen SA, Mazure C. The Yale-Brown Obsessive Compulsive Scale: I. Development, use, and reliability. Arch Gen Psychiatry. 1989; 46:1006-1011.
45. Oldfield RC. The assessment and analysis of nandedness: The Edinburgh Inventory. Neuropsychologia. 1971;9:97-113.
46. Nelson HE. National Adult Reading Test (NART): Test Manual. Windsor, England: MFER Nelson; 1982.
47. Milner B. Interhemispheric differences in the localization of psychological processes in man. Br Med Bull. 1971;27:272-277.
48. Robbins TW. A critique of the methods available for the measurement of spontaneous locomotor activity. In: Iversen LL, Iversen SD, Synder SH, eds. Handbook of Psychopharmacology. New York, NY: Plenum Publishing Corp; 1977: 37-82.
49. Sahakian BJ, Downes JJ, Eagger S, Evenden JL, Levy R, Philpot MP, Roberts AC, Robbins TW. Sparing of attentional relative to mnemonic function in a subgroup of patients with dementia of the Alzheimer type. Neuropsychologia. 1990; 28:1197-1123.
50. McNally RI, Kohlbeck PA. Reality monitoring in obsessive-compulsive disorder. Behav Res Ther. 1993;31:249-253.
51. Ecker W, Engelkamp J. Memory for actions in obsessive-compulsive disorder. Behav Cogn Psychother. 1995;23:349-371.
52. Dirson S, Bouvard M, Cottraux J, Martin R. Visual memory impairment in patients with obsessive-compulsive disorder: a controlled study. Psychother Psychosom. 1995;63:22-31.
53. Aronowitz BR, Hollander E, DeCaria C, Cohen L. Neuropsychology of obsessivecompulsive disorder: preliminary findings. Neuropsychiatry Neuropsychol Behav Neurol. 1994;7:81-86.
54. Abbruzzese M, Fern S, Scarone S. Wisconsin Card Sorting Test performance in obsessive-compulsive disorder: no evidence for involvement of dorsolateral prefrontal cortex. Psychiatry Res. 1995;58:37-43.
55. Modell JG, Mountz JM, Curtis GC, Greden JF, Neurophysioiogic dysfunction in basal ganglia/limbic striatal and thalamocortical circuits as a pathogenetic mechanism of obsessive-compulsive disorder. J Neuropsychiatry Clin Neurosci. 1989; 1:27-36.
56. Insel TR. Toward a neuroanatomy of obsessive-compulsive disorder. Arch Gen Psychiatry. 1992;49:739-744.
57. Rapoport JL. Obsessive compulsive disorder and basal ganglia dysfunction. Psychol Med. 1990;20:465-469.
58. Cummings JL. Frontal-subcortical circuits and human behavior. Arch Neurol. 1993; 50:873-880.
59. Owen AM, Evans AC, Petrides M. Evidence for a two-stage model of spatial working memory processing within the lateral frontal cortex: a positron emission tomography study. Cereb Cortex. 1996;6:31-38.
60. Owen AM, Doyon J, Petrides M, Evans AC. Planning and spatial working memory: a positron emission tomography study in humans. Eur J Neurosci. 1996;8:353- 364.
61. Dias R, Robbins TW, Roberts AC. Dissociation in prefrontal cortex of affective and attentional shifts. Nature. 1996;380:69-72.
62. Sawle GV, Hymas NF, Lees AS, Frackowiak RSJ. Obsessional slowness: functional studies with positron emission tomography. Brain. 1991;114:2191-2202.
63. Rauch SL, Savage CR, Alpert NM, Miguel BC, Baer L, Breiter HC, Fischman AS, Manzo PA, Moretti C, Jenike MA. A positron emission tomography study of simple phobic symptom provocation. Arch Gen Psychiatry. 1995;52:20-28.
64. McGuire PK. The brain in obsessive-compulsive disorder, J Neurol Neurosurg Psychiatry. 1995;59:457-459.
65. Rauch SL, Savage CR, Alpert NM, Dougherty D, Kendrick A, Curran T, Brown HD, Manzo P, Fischman AS, Jenike MA. Probing striatal function in obsessivecompulsive disorder using PET and a sequence learning task. Neuroimage. 1996; 3(suppl):s507.