Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatin

Nucleic Acids Research

Volumn 42, Issue 4, 2014, Pages 2330-2345

  Lan, Li ^a,b   Nakajima, Satoshi ^a,b   Wei, Leizhen ^a,b   Sun, Luxi ^b,c   Hsieh, Ching Lung ^a,b   Sobol, Robert W ^a,b,d   Bruchez, Marcel ^e   Van Houten, Bennett ^a,b   Yasui, Akira ^f   Levine, Arthur S ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^c Tsinghua University   (China)

^d UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^e CARNEGIE MELLON UNIVERSITY   (United States)

^f TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CYCLINE; DNA DIRECTED DNA POLYMERASE BETA; DNA GLYCOSYLTRANSFERASE; GENOMIC DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PHOTOSENSITIZING AGENT; PROTEIN FEN1; REACTIVE OXYGEN METABOLITE; REPRESSOR PROTEIN; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELLULAR DISTRIBUTION; CHROMATIN CONDENSATION; CONTROLLED STUDY; DNA DAMAGE; EUCHROMATIN; EXCISION REPAIR; GENE CASSETTE; GENE INDUCTION; GENE LOCUS; HETEROCHROMATIN; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; PROTEIN TRANSPORT; REPRESSOR GENE; TRANSCRIPTION INITIATION;

CELL LINE; CHROMATIN; DNA DAMAGE; DNA GLYCOSYLASES; DNA POLYMERASE BETA; DNA REPAIR; DNA REPAIR ENZYMES; EUCHROMATIN; FLAP ENDONUCLEASES; GENOME; GREEN FLUORESCENT PROTEINS; HETEROCHROMATIN; HUMANS; LASERS; OXIDATION-REDUCTION; POLY(ADP-RIBOSE) POLYMERASES; PROLIFERATING CELL NUCLEAR ANTIGEN; REACTIVE OXYGEN SPECIES; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; RESPONSE ELEMENTS; TRANS-ACTIVATORS;

EID: 84895811308     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt1233     Document Type: Article

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