X chromosome inactivation in the cycle of life

Development (Cambridge)

Volumn 139, Issue 12, 2012, Pages 2085-2089

  Barakat, Tahsin Stefan ^a   Gribnau, Joost ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Tsix; X chromosome inactivation; XCI activator; XCI inhibitor; Xist

Indexed keywords

KRUPPEL LIKE FACTOR 2; KRUPPEL LIKE FACTOR 4; LIVER RECEPTOR HOMOLOG 1; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR SOX2;

ARTICLE; DIPLOIDY; DOWN REGULATION; EMBRYONIC STEM CELL; GENE CONTROL; GENE EXPRESSION; HUMAN; LIFE CYCLE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; TRANSACTIVATION; TRANSGENE; UPREGULATION; X CHROMOSOME INACTIVATION;

ANIMALS; GENOMIC IMPRINTING; LIFE CYCLE STAGES; REGULATORY SEQUENCES, NUCLEIC ACID; X CHROMOSOME; X CHROMOSOME INACTIVATION;

MAMMALIA; MUS;

EID: 84861364476     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.069328     Document Type: Article

References (60)

1. Augui, S., Filion, G. J., Huart, S., Nora, E., Guggiari, M., Maresca, M., Stewart, A. F. and Heard, E. (2007). Sensing X chromosome pairs before X inactivation via a novel X-pairing region of the Xic. Science 318, 1632-1636.
2. Bacher, C. P., Guggiari, M., Brors, B., Augui, S., Clerc, P., Avner, P., Eils, R. and Heard, E. (2006). Transient colocalization of X-inactivation centres accompanies the initiation of X inactivation. Nat. Cell Biol. 8, 293-299.
3. Bao, S., Tang, F., Li, X., Hayashi, K., Gillich, A., Lao, K. and Surani, M. A. (2009). Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells. Nature 461, 1292-1295.
4. Barakat, T. S., Gunhanlar, N., Pardo, C. G., Achame, E. M., Ghazvini, M., Boers, R., Kenter, A., Rentmeester, E., Grootegoed, J. A. and Gribnau, J. (2011). RNF12 activates Xist and is essential for X chromosome inactivation. PLoS Genet. 7, e1002001.
5. Borsani, G., Tonlorenzi, R., Simmler, M. C., Dandolo, L., Arnaud, D., Capra, V., Grompe, M., Pizzuti, A., Muzny, D., Lawrence, C. et al. (1991). Characterization of a murine gene expressed from the inactive X chromosome. Nature 351, 325-329.
6. Boyer, L. A., Plath, K., Zeitlinger, J., Brambrink, T., Medeiros, L. A., Lee, T. I., Levine, S. S., Wernig, M., Tajonar, A., Ray, M. K. et al. (2006). Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441, 349-353.
7. Brockdorff, N., Ashworth, A., Kay, G. F., Cooper, P., Smith, S., McCabe, V. M., Norris, D. P., Penny, G. D., Patel, D. and Rastan, S. (1991). Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome. Nature 351, 329-331.
8. Brons, I. G., Smithers, L. E., Trotter, M. W., Rugg-Gunn, P., Sun, B., Chuva de Sousa Lopes, S. M., Howlett, S. K., Clarkson, A., Ahrlund-Richter, L., Pedersen, R. A. et al. (2007). Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 448, 191-195.
9. Brown, C. J., Ballabio, A., Rupert, J. L., Lafreniere, R. G., Grompe, M., Tonlorenzi, R. and Willard, H. F. (1991). A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome. Nature 349, 38-44.
10. Brown, C. J., Hendrich, B. D., Rupert, J. L., Lafreniere, R. G., Xing, Y., Lawrence, J. and Willard, H. F. (1992). The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus. Cell 71, 527-542.
11. Chaumeil, J., Le Baccon, P., Wutz, A. and Heard, E. (2006). A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced. Genes Dev. 20, 2223-2237.
12. Chureau, C., Chantalat, S., Romito, A., Galvani, A., Duret, L., Avner, P. and Rougeulle, C. (2011). Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region. Hum. Mol. Genet. 20, 705-718.
13. Chuva de Sousa Lopes, S. M., Hayashi, K., Shovlin, T. C., Mifsud, W., Surani, M. A. and McLaren, A. (2008). X chromosome activity in mouse XX primordial germ cells. PLoS Genet. 4, e30.
14. Clerc, P. and Avner, P. (1998). Role of the region 3' to Xist exon 6 in the counting process of X-chromosome inactivation. Nat. Genet. 19, 249-253.
15. de Napoles, M., Nesterova, T. and Brockdorff, N. (2007). Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells. PLoS ONE 2, e860.
16. Do, J. T., Han, D. W., Gentile, L., Sobek-Klocke, I., Stehling, M., Lee, H. T. and Scholer, H. R. (2007). Erasure of cellular memory by fusion with pluripotent cells. Stem Cells 25, 1013-1020.
17. Donohoe, M. E., Zhang, L. F., Xu, N., Shi, Y. and Lee, J. T. (2007). Identification of a Ctcf cofactor, Yy1, for the X chromosome binary switch. Mol. Cell 25, 43-56.
18. Donohoe, M. E., Silva, S. S., Pinter, S. F., Xu, N. and Lee, J. T. (2009). The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting. Nature 460, 128-132.
19. Eggan, K., Akutsu, H., Hochedlinger, K., Rideout, W., 3rd, Yanagimachi, R. and Jaenisch, R. (2000). X-Chromosome inactivation in cloned mouse embryos. Science 290, 1578-1581.
20. Grumbach, M. M., Morishima, A. and Taylor, J. H. (1963). Human sex chromosome abnormalities in relation to DNA replication and heterochromatinization. Proc. Natl. Acad. Sci. USA 49, 581-589.
21. Guo, G. and Smith, A. (2010). A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency. Development 137, 3185-3192.
22. Guo, G., Yang, J., Nichols, J., Hall, J. S., Eyres, I., Mansfield, W. and Smith, A. (2009). Klf4 reverts developmentally programmed restriction of ground state pluripotency. Development 136, 1063-1069.
23. Huynh, K. D. and Lee, J. T. (2003). Inheritance of a pre-inactivated paternal X chromosome in early mouse embryos. Nature 426, 857-862.
24. Jonkers, I., Barakat, T. S., Achame, E. M., Monkhorst, K., Kenter, A., Rentmeester, E., Grosveld, F., Grootegoed, J. A. and Gribnau, J. (2009). RNF12 is an X-Encoded dose-dependent activator of X chromosome inactivation. Cell 139, 999-1011.
25. Kim, J., Chu, J., Shen, X., Wang, J. and Orkin, S. H. (2008). An extended transcriptional network for pluripotency of embryonic stem cells. Cell 132, 1049-1061.
26. Lee, J. T. (2000). Disruption of imprinted X inactivation by parent-of-origin effects at Tsix. Cell 103, 17-27.
27. Lee, J. T. and Lu, N. (1999). Targeted mutagenesis of Tsix leads to nonrandom X inactivation. Cell 99, 47-57.
28. Lee, J. T., Davidow, L. S. and Warshawsky, D. (1999). Tsix, a gene antisense to Xist at the X-inactivation centre. Nat. Genet. 21, 400-404.
29. Lyon, M. F. (1961). Gene action in the X-chromosome of the mouse (Mus musculus L.). Nature 190, 372-373.
30. Maherali, N., Sridharan, R., Xie, W., Utikal, J., Eminli, S., Arnold, K., Stadtfeld, M., Yachechko, R., Tchieu, J., Jaenisch, R. et al. (2007). Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1, 55-70.
31. Mak, W., Nesterova, T. B., de Napoles, M., Appanah, R., Yamanaka, S., Otte, A. P. and Brockdorff, N. (2004). Reactivation of the paternal X chromosome in early mouse embryos. Science 303, 666-669.
32. Marahrens, Y., Panning, B., Dausman, J., Strauss, W. and Jaenisch, R. (1997). Xist-deficient mice are defective in dosage compensation but not spermatogenesis. Genes Dev. 11, 156-166.
33. Masui, O., Bonnet, I., Le Baccon, P., Brito, I., Pollex, T., Murphy, N., Hupe, P., Barillot, E., Belmont, A. S. and Heard, E. (2011). Live-cell chromosome dynamics and outcome of X chromosome pairing events during ES cell differentiation. Cell 145, 447-458.
34. Mise, N., Fuchikami, T., Sugimoto, M., Kobayakawa, S., Ike, F., Ogawa, T., Tada, T., Kanaya, S., Noce, T. and Abe, K. (2008). Differences and similarities in the developmental status of embryo-derived stem cells and primordial germ cells revealed by global expression profiling. Genes Cells 13, 863-877.
35. Mlynarczyk-Evans, S., Royce-Tolland, M., Alexander, M. K., Andersen, A. A., Kalantry, S., Gribnau, J. and Panning, B. (2006). X chromosomes alternate between two states prior to random X-inactivation. PLoS Biol. 4, e159.
36. Monk, M. and Harper, M. I. (1979). Sequential X chromosome inactivation coupled with cellular differentiation in early mouse embryos. Nature 281, 311-313.
37. Monk, M. and McLaren, A. (1981). X-chromosome activity in foetal germ cells of the mouse. J. Embryol. Exp. Morphol. 63, 75-84.
38. Monkhorst, K., Jonkers, I., Rentmeester, E., Grosveld, F. and Gribnau, J. (2008). X inactivation counting and choice is a stochastic process: evidence for involvement of an X-linked activator. Cell 132, 410-421.
39. Monkhorst, K., de Hoon, B., Jonkers, I., Mulugeta Achame, E., Monkhorst, W., Hoogerbrugge, J., Rentmeester, E., Westerhoff, H. V., Grosveld, F., Grootegoed, J. A. et al. (2009). The probability to initiate X chromosome inactivation is determined by the X to autosomal ratio and X chromosome specific allelic properties. PLoS ONE 4, e5616.
40. Navarro, P., Chambers, I., Karwacki-Neisius, V., Chureau, C., Morey, C., Rougeulle, C. and Avner, P. (2008). Molecular coupling of Xist regulation and pluripotency. Science 321, 1693-1695.
41. Navarro, P., Oldfield, A., Legoupi, J., Festuccia, N., Dubois, A., Attia, M., Schoorlemmer, J., Rougeulle, C., Chambers, I. and Avner, P. (2010). Molecular coupling of Tsix regulation and pluripotency. Nature 468, 457-460.
42. Navarro, P., Moffat, M., Mullin, N. P. and Chambers, I. (2011). The Xinactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells. Hum. Genet. 130, 255-264.
43. Nesterova, T. B., Senner, C. E., Schneider, J., Alcayna-Stevens, T., Tattermusch, A., Hemberger, M. and Brockdorff, N. (2011). Pluripotency factor binding and Tsix expression act synergistically to repress Xist in undifferentiated embryonic stem cells. Epigenetics & Chromatin 4, 17.
44. Ogawa, Y. and Lee, J. T. (2003). Xite, X-inactivation intergenic transcription elements that regulate the probability of choice. Mol. Cell 11, 731-743.
45. Okamoto, I., Otte, A. P., Allis, C. D., Reinberg, D. and Heard, E. (2004). Epigenetic dynamics of imprinted X inactivation during early mouse development. Science 303, 644-649.
46. Okamoto, I., Arnaud, D., Le Baccon, P., Otte, A. P., Disteche, C. M., Avner, P. and Heard, E. (2005). Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice. Nature 438, 369-373.
47. Okamoto, I., Patrat, C., Thepot, D., Peynot, N., Fauque, P., Daniel, N., Diabangouaya, P., Wolf, J. P., Renard, J. P., Duranthon, V. et al. (2011). Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development. Nature 472, 370-374.
48. Penny, G. D., Kay, G. F., Sheardown, S. A., Rastan, S. and Brockdorff, N. (1996). Requirement for Xist in X chromosome inactivation. Nature 379, 131-137.
49. Sado, T., Wang, Z., Sasaki, H. and Li, E. (2001). Regulation of imprinted Xchromosome inactivation in mice by Tsix. Development 128, 1275-1286.
50. Shin, J., Bossenz, M., Chung, Y., Ma, H., Byron, M., Taniguchi-Ishigaki, N., Zhu, X., Jiao, B., Hall, L. L., Green, M. R. et al. (2010). Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice. Nature 467, 977-981.
51. Silva, J., Nichols, J., Theunissen, T. W., Guo, G., van Oosten, A. L., Barrandon, O., Wray, J., Yamanaka, S., Chambers, I. and Smith, A. (2009). Nanog is the gateway to the pluripotent ground state. Cell 138, 722-737.
52. Sugimoto, M. and Abe, K. (2007). X chromosome reactivation initiates in nascent primordial germ cells in mice. PLoS Genet. 3, e116.
53. Takagi, N. and Sasaki, M. (1975). Preferential inactivation of the paternally derived X chromosome in the extraembryonic membranes of the mouse. Nature 256, 640-642.
54. Takagi, N., Yoshida, M. A., Sugawara, O. and Sasaki, M. (1983). Reversal of Xinactivation in female mouse somatic cells hybridized with murine teratocarcinoma stem cells in vitro. Cell 34, 1053-1062.
55. Tam, P. P., Zhou, S. X. and Tan, S. S. (1994). X-chromosome activity of the mouse primordial germ cells revealed by the expression of an X-linked lacZ transgene. Development 120, 2925-2932.
56. Tesar, P. J., Chenoweth, J. G., Brook, F. A., Davies, T. J., Evans, E. P., Mack, D. L., Gardner, R. L. and McKay, R. D. (2007). New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 448, 196-199.
57. Tian, D., Sun, S. and Lee, J. T. (2011). The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation. Cell 143, 390-403.
58. Williams, L. H., Kalantry, S., Starmer, J. and Magnuson, T. (2011). Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass. Development 138, 2049-2057.
59. Xu, N., Tsai, C. L. and Lee, J. T. (2006). Transient homologous chromosome pairing marks the onset of X inactivation. Science 311, 1149-1152.
60. Xue, F., Tian, X. C., Du, F., Kubota, C., Taneja, M., Dinnyes, A., Dai, Y., Levine, H., Pereira, L. V. and Yang, X. (2002). Aberrent patterns of X chromosome inactivation in bovine clones. Nat. Genet. 31, 216-220.