Structural basis for phototoxicity of the genetically encoded photosensitizer KillerRed

Journal of Biological Chemistry

Volumn 284, Issue 46, 2009, Pages 32028-32039

  Pletnev, Sergei ^a   Gurskaya, Nadya G ^b   Pletneva, Nadya V ^b   Lukyanov, Konstantin A ^b   Chudakov, Dmitri M ^b   Martynov, Vladimir I ^b   Popov, Vladimir O ^c   Kovalchuk, Mikhail V ^d   Wlodawer, Alexander ^e   Dauter, Zbigniew ^a   Pletnev, Vladimir ^b  

^a SAIC FREDERICK INC   (United States)

^b SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^c BACH INSTITUTE OF BIOCHEMISTRY   (Russian Federation)

^d SHUBNIKOV INSTITUTE OF CRYSTALLOGRAPHY   (Russian Federation)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL POPULATIONS; CRYSTALLOGRAPHIC STUDIES; FLUORESCENT PROTEIN; HIGH RESOLUTION; PHOTO-TOXICITY; REACTION CHAINS; RED FLUORESCENT PROTEINS; SITE DIRECTED MUTAGENESIS; STRUCTURAL BASIS; STRUCTURAL FEATURE; STRUCTURE-BASED; STRUCTURE-FUNCTION RELATIONSHIP; TARGET PROTEINS;

CELL CULTURE; CELL PROLIFERATION; CHROMOPHORES; FLUORESCENCE; PHOTODYNAMIC THERAPY; PHOTOSENSITIZERS;

PROTEINS;

GLUTAMINE; GREEN FLUORESCENT PROTEIN; KILLERRED; OLIGOMER; SERINE; UNCLASSIFIED DRUG;

ARTICLE; BLEACHING; CARBOXY TERMINAL SEQUENCE; CHROMATOPHORE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; HYDROGEN BOND; OLIGOMERIZATION; PHOTOTOXICITY; PRIORITY JOURNAL; PROTEIN PROCESSING; SITE DIRECTED MUTAGENESIS;

CRYSTALLOGRAPHY, X-RAY; DERMATITIS, PHOTOTOXIC; GREEN FLUORESCENT PROTEINS; HUMANS; LIGHT; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHOTOSENSITIZING AGENTS; PROTEIN CONFORMATION;

EID: 70450231499     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.054973     Document Type: Article

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