Inhibitory effects of monoterpenes on human TRPA1 and the structural basis of their activity

Journal of Physiological Sciences

Volumn 64, Issue 1, 2014, Pages 47-57

  Takaishi, Masayuki ^a,b   Uchida, Kunitoshi ^a,b   Fujita, Fumitaka ^a,c   Tominaga, Makoto ^a,c  

^a OKAZAKI INSTITUTE FOR INTEGRATIVE BIOSCIENCE   (Japan)

^b C   (Japan)

^c GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

Author keywords

Hydroxyl group; Monoterpene; Pain relief; TRPA1

Indexed keywords

2 METHYLISOBORNEOL; 2-METHYLISOBORNEOL; ANALGESIC AGENT; BORNANE DERIVATIVE; CALCIUM CHANNEL; CAMPHOR; CINEOLE; CYCLOHEXANOL DERIVATIVE; FENCHOL; HYDROXIDE; HYDROXIDE ION; ISOBORNEOL; NERVE PROTEIN; NORBORNANE DERIVATIVE; TERPENE; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRPA1 PROTEIN, HUMAN;

ARTICLE; CELL CULTURE; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; HEK293 CELL LINE; HUMAN; PAIN;

ANALGESICS; BORNANES; CALCIUM CHANNELS; CAMPHOR; CELLS, CULTURED; CYCLOHEXANOLS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEK293 CELLS; HUMANS; HYDROXIDES; MONOTERPENES; NERVE TISSUE PROTEINS; NORBORNANES; PAIN; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 84895798857     PISSN: 18806546     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12576-013-0289-0     Document Type: Article

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