Intracellular alkalization causes pain sensation through activation of TRPA1 in mice

Journal of Clinical Investigation

Volumn 118, Issue 12, 2008, Pages 4049-4057

  Fujita, Fumitaka ^a,b   Uchida, Kunitoshi ^a,c,d   Moriyama, Tomoko ^e   Shima, Asako ^f   Shibasaki, Koji ^a,c,d   Inada, Hitoshi ^a,d   Sokabe, Takaaki ^a,d   Tominaga, Makoto ^a,c,d  

^a OKAZAKI INSTITUTE FOR INTEGRATIVE BIOSCIENCE   (Japan)

^b C   (Japan)

^c NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^d GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^e HIROSAKI UNIVERSITY   (Japan)

^f NIHON UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIUM CHLORIDE; CALCIUM ION; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 2;

ALKALINIZATION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PH; CELL STRAIN HEK293; CONTROLLED STUDY; HUMAN; HUMAN CELL; MALE; MOUSE; NEUROMODULATION; NOCICEPTION; NONHUMAN; PAIN; PATCH CLAMP; PRIORITY JOURNAL;

ANIMALS; BEHAVIOR, ANIMAL; CALCIUM; HUMANS; HYDROGEN-ION CONCENTRATION; MICE; MICE, MUTANT STRAINS; PAIN THRESHOLD; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 57449100300     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI35957     Document Type: Article

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