1,8-Cineol, a food flavoring agent, prevents ethanol-induced gastric injury in rats

Digestive Diseases and Sciences

Volumn 46, Issue 2, 2001, Pages 331-337

  Santos, F A ^a   Rao, V S N ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

1,8 cineole; Ethanol; Gastric mucosal lesions; Gastric mucus; Nonprotein sulfhydryls

Indexed keywords

8 PHENYLTHEOPHYLLINE; ADENOSINE; ALCOHOL; CIMETIDINE; CINEOLE; FLAVORING AGENT; HISTAMINE H2 RECEPTOR ANTAGONIST; LIPOXYGENASE INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NORDIHYDROGUAIARETIC ACID; THIOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH INJURY; STOMACH JUICE; STOMACH MUCOSA LESION; STOMACH MUCUS; STOMACH PROTECTION; STOMACH SECRETION; STOMACH WALL;

ADMINISTRATION, ORAL; ALCOHOLISM; ANIMALS; ANTIOXIDANTS; CYCLOHEXANOLS; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; ETHANOL; FLAVORING AGENTS; GASTRIC JUICE; GASTRITIS; MALE; MENTHOL; MONOTERPENES; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; RATS; RATS, WISTAR; TERPENES;

EID: 0035085944     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005604932760     Document Type: Article

References (44)

1. Blood levels of 1,8-cineole and locomotor activity of mice after inhalation and oral administration of rosemary oil
2. Volatile constituents of Psidium pohlianum Berg. and Psidium guyanensis Pers
3. Essential plant oils and headache mechanisms
4. Monographs on botanical flavouring substances used in foods. Part V
5. Pharmacology of rosemary (Rosmarinus officinales Linn.) and its therapeutic potentials
6. Antibacterial and antifungal activity of aromatic constituents of essential oils
7. The absorption of drugs and poisons through the skin and mucous membranes
8. Terpenes and the lipid-protein-partitioning theory of skin penetration enhancement
9. The antitussive effects of menthol, camphor and cineole in conscious guinea-pigs
10. Formulation optimization of indomethacin gels containing a combination of three kinds of cyclic monoterpenes as percutaneous penetration enhancers
11. Inhibition of cytokine production and arachidonic acid metabolism by eucalyptol (1,8-cineole) in human blood monocytes in vitro
12. Anti-inflammatory effects of eucalyptol (1,8-cineole) in bronchial asthma: Inhibition of arachidonic acid metabolism in human blood monocytes ex vivo
13. Anti-inflammatory and antinociceptive effects of 1,8-cineole, a terpenoid oxide present in many plant essential oils
14. Early vascular injury and increased vascularpermeability in gastric mucosal injury caused by ethanol in the rat
15. 2 generation in rats by flavonoids of Dittrichia viscosa
16. Gastric cytoprotection of the non-steroidal anti-inflammatory sesquiterpene, β-caryophyllene
17. Gastroprotective agents for the prevention of NSAID-induced gastropathy
18. Protective effect of a purified fraction against reactive oxygen radicals. In vivo and in vitro study
19. Adenosine protects against indomethacin-induced gastric damage in rats
20. Gastric antisecretory, antiulcer and cytoprotectiveproperties of 9-hydroxy. 19,20-Bisnor-prostanoic acid in experimental animals
21. Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: Implications for gastrointestinal toxicity
22. Cytoprotection by prostaglandins
23. Mild irritants prevent gastric mucosa through adaptive cytoprotection mediated by prostaglandins
24. A method for the quantitative estimation of gastric barrier mucus
25. A quantitative method for measuring spontaneous gastric secretion in the rat
26. Estimation of total, protein bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent
27. 4 in rat gastric mucosa
28. Role of leukotrienes in acute gastric lesions induced by ethanol, taurocholate, aspirin, platelet-activating factor and stress in rats
29. Early vascular injury and increased vascular permeability in gastric mucosal injury caused by ethanol in the rat
30. Possible role of oxygen free radicals in ethanol-induced gastric mucosal damage in rats
31. Removing oxygen-derived free radicals stimulate healing of ethanol-induced erosive gastritis in the rat
32. Studies on the mechanism of ethanol-induced gastric damage in rats
33. Gastric blood flow in ulcer diseases
34. Microcirculatory stasis precedes tissue necrosis in ethanol-induced gastric mucosal injury in the rat
35. Interference of myrtol standardized with inflammatory and allergic mediators
36. Protective role of intracellular glutathione against ethanol-induced damage in cultured rat gastric mucosal cells
37. Role of glutathione in gastric mucosal cytoprotection
38. Sulfyhdryl compounds may mediate gastric cytoprotection
39. Central gastric antisecretory action of adenosine in the rat
40. Adenosine, antioxidant enzymes and cytoprotection
41. Modulatory action of adenosine on gastric function and ethanol-induced mucosal damage in rats
42. Nitric oxide in the gastrointestinal physiology and pathology
43. Correlation of quantitative changes of gastric mucosal glycoproteins with ethanol-induced gastric damage in rats
44. Functional imaging of effects of fragrances on the human brain after prolonged inhalation