메뉴 건너뛰기




Volumn 22, Issue 3, 2014, Pages 730-738

Evidence for the role of AMPK in regulating PGC-1 alpha expression and mitochondrial proteins in mouse epididymal adipose tissue

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; MITOCHONDRIAL ENZYME; NORADRENALIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA;

EID: 84895797258     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1002/oby.20605     Document Type: Article
Times cited : (135)

References (35)
  • 1
    • 33644660537 scopus 로고    scopus 로고
    • PGC-1 coactivators: Inducible regulators of energy metabolism in health and disease
    • Finck BN, Kelly DP,. PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J Clin Invest 2006; 116: 615-622.
    • (2006) J Clin Invest , vol.116 , pp. 615-622
    • Finck, B.N.1    Kelly, D.P.2
  • 2
    • 42949083922 scopus 로고    scopus 로고
    • Modest PGC-1alpha overexpression in muscle in vivo is sufficient to increase insulin sensitivity and palmitate oxidation in subsarcolemmal, not intermyofibrillar, mitochondria
    • Benton CR, Nickerson JG, Lally J, et al. Modest PGC-1alpha overexpression in muscle in vivo is sufficient to increase insulin sensitivity and palmitate oxidation in subsarcolemmal, not intermyofibrillar, mitochondria. J Biol Chem 2008; 283: 4228-4240.
    • (2008) J Biol Chem , vol.283 , pp. 4228-4240
    • Benton, C.R.1    Nickerson, J.G.2    Lally, J.3
  • 3
    • 0037102256 scopus 로고    scopus 로고
    • Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres
    • Lin J, Wu H, Tarr PT, et al. Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature 2002; 418: 797-801.
    • (2002) Nature , vol.418 , pp. 797-801
    • Lin, J.1    Wu, H.2    Tarr, P.T.3
  • 4
    • 22144434964 scopus 로고    scopus 로고
    • Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle
    • Arany Z, He H, Lin J, et al. Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle. Cell Metab 2005; 1: 259-271.
    • (2005) Cell Metab , vol.1 , pp. 259-271
    • Arany, Z.1    He, H.2    Lin, J.3
  • 5
    • 0035977050 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase activates peroxisome proliferator-activated receptor alpha: A potential role in the cardiac metabolic stress response
    • Barger PM, Browning AC, Garner AN, Kelly DP., p38 mitogen-activated protein kinase activates peroxisome proliferator-activated receptor alpha: a potential role in the cardiac metabolic stress response. J Biol Chem 2001; 276: 44495-44501.
    • (2001) J Biol Chem , vol.276 , pp. 44495-44501
    • Barger, P.M.1    Browning, A.C.2    Garner, A.N.3    Kelly, D.P.4
  • 6
    • 0033803048 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis
    • Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP,. Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest 2000; 106: 847-856.
    • (2000) J Clin Invest , vol.106 , pp. 847-856
    • Lehman, J.J.1    Barger, P.M.2    Kovacs, A.3    Saffitz, J.E.4    Medeiros, D.M.5    Kelly, D.P.6
  • 7
    • 84857626157 scopus 로고    scopus 로고
    • The transcriptional coactivators, PGC-1alpha and beta, cooperate to maintain cardiac mitochondrial function during the early stages of insulin resistance
    • Mitra R, Nogee DP, Zechner JF, et al. The transcriptional coactivators, PGC-1alpha and beta, cooperate to maintain cardiac mitochondrial function during the early stages of insulin resistance. J Mol Cell Cardiol 2011; 52: 701-710.
    • (2011) J Mol Cell Cardiol , vol.52 , pp. 701-710
    • Mitra, R.1    Nogee, D.P.2    Zechner, J.F.3
  • 8
    • 0042357130 scopus 로고    scopus 로고
    • Acquirement of brown fat cell features by human white adipocytes
    • Tiraby C, Tavernier G, Lefort C, et al. Acquirement of brown fat cell features by human white adipocytes. J Biol Chem 2003; 278: 33370-33376.
    • (2003) J Biol Chem , vol.278 , pp. 33370-33376
    • Tiraby, C.1    Tavernier, G.2    Lefort, C.3
  • 9
    • 84862162100 scopus 로고    scopus 로고
    • Development of insulin resistance in mice lacking PGC-1alpha in adipose tissues
    • Kleiner S, Mepani RJ, Laznik D, et al. Development of insulin resistance in mice lacking PGC-1alpha in adipose tissues. Proc Natl Acad Sci U S A 2012; 109: 9635-9640.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 9635-9640
    • Kleiner, S.1    Mepani, R.J.2    Laznik, D.3
  • 11
    • 63849186508 scopus 로고    scopus 로고
    • Exercise and adrenaline increase PGC-1{alpha} mRNA expression in rat adipose tissue
    • Sutherland LN, Bomhof MR, Capozzi LC, Basaraba SA, Wright DC,. Exercise and adrenaline increase PGC-1{alpha} mRNA expression in rat adipose tissue. J Physiol 2009; 587: 1607-1617.
    • (2009) J Physiol , vol.587 , pp. 1607-1617
    • Sutherland, L.N.1    Bomhof, M.R.2    Capozzi, L.C.3    Basaraba, S.A.4    Wright, D.C.5
  • 12
    • 77950226740 scopus 로고    scopus 로고
    • Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes
    • Petrovic N, Walden TB, Shabalina IG, Timmons JA, Cannon B, Nedergaard J,. Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes. J Biol Chem 2010; 285: 7153-7164.
    • (2010) J Biol Chem , vol.285 , pp. 7153-7164
    • Petrovic, N.1    Walden, T.B.2    Shabalina, I.G.3    Timmons, J.A.4    Cannon, B.5    Nedergaard, J.6
  • 13
    • 79959601726 scopus 로고    scopus 로고
    • Intracellular fatty acids suppress beta-adrenergic induction of PKA-targeted gene expression in white adipocytes
    • Mottillo EP, Granneman JG,. Intracellular fatty acids suppress beta-adrenergic induction of PKA-targeted gene expression in white adipocytes. Am J Physiol Endocrinol Metab 2012; 301: E122-E131.
    • (2012) Am J Physiol Endocrinol Metab , vol.301
    • Mottillo, E.P.1    Granneman, J.G.2
  • 14
    • 84872667668 scopus 로고    scopus 로고
    • AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity
    • O'Neill HM, Holloway GP, Steinberg GR,. AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: implications for obesity. Mol Cell Endocrinol 2012; 366: 135-151.
    • (2012) Mol Cell Endocrinol , vol.366 , pp. 135-151
    • O'Neill, H.M.1    Holloway, G.P.2    Steinberg, G.R.3
  • 15
    • 34547545892 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
    • Jager S, Handschin C, St-Pierre J, Spiegelman BM,. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci U S A 2007; 104: 12017-12022.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 12017-12022
    • Jager, S.1    Handschin, C.2    St-Pierre, J.3    Spiegelman, B.M.4
  • 16
    • 77950192925 scopus 로고    scopus 로고
    • Dysregulation of lipolysis and lipid metabolism in visceral and subcutaneous adipocytes by high-fat diet: Role of ATGL, HSL, and AMPK
    • Gaidhu MP, Anthony NM, Patel P, Hawke TJ, Ceddia RB,. Dysregulation of lipolysis and lipid metabolism in visceral and subcutaneous adipocytes by high-fat diet: role of ATGL, HSL, and AMPK. Am J Physiol Cell Physiol 2010; 298: C961-C971.
    • (2010) Am J Physiol Cell Physiol , vol.298
    • Gaidhu, M.P.1    Anthony, N.M.2    Patel, P.3    Hawke, T.J.4    Ceddia, R.B.5
  • 17
    • 47749085114 scopus 로고    scopus 로고
    • AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: Potential mechanism and physiological relevance
    • Gauthier MS, Miyoshi H, Souza SC, et al. AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance. J Biol Chem 2008; 283: 16514-16524.
    • (2008) J Biol Chem , vol.283 , pp. 16514-16524
    • Gauthier, M.S.1    Miyoshi, H.2    Souza, S.C.3
  • 18
    • 34247853279 scopus 로고    scopus 로고
    • Adrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytes
    • Koh HJ, Hirshman MF, He H, et al. Adrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytes. Biochem J 2007; 403: 473-481.
    • (2007) Biochem J , vol.403 , pp. 473-481
    • Koh, H.J.1    Hirshman, M.F.2    He, H.3
  • 19
    • 0031731021 scopus 로고    scopus 로고
    • The activation of p38 MAPK by the beta-adrenergic agonist isoproterenol in rat epididymal fat cells
    • Moule SK, Denton RM,. The activation of p38 MAPK by the beta-adrenergic agonist isoproterenol in rat epididymal fat cells. FEBS Lett 1998; 439: 287-290.
    • (1998) FEBS Lett , vol.439 , pp. 287-290
    • Moule, S.K.1    Denton, R.M.2
  • 20
    • 78349250513 scopus 로고    scopus 로고
    • Epinephrine-mediated regulation of PDK4 mRNA in rat adipose tissue
    • Wan Z, Thrush AB, Legare M, et al. Epinephrine-mediated regulation of PDK4 mRNA in rat adipose tissue. Am J Physiol Cell Physiol 2010; 299: C1162-C1170.
    • (2010) Am J Physiol Cell Physiol , vol.299
    • Wan, Z.1    Thrush, A.B.2    Legare, M.3
  • 21
    • 84878502593 scopus 로고    scopus 로고
    • Loss of neuronatin promotes "browning" of primary mouse adipocytes while reducing Glut1-mediated glucose disposal
    • Gburcik V, Cleasby ME, Timmons JA,. Loss of neuronatin promotes "browning" of primary mouse adipocytes while reducing Glut1-mediated glucose disposal. Am J Physiol Endocrinol Metab 2013; 304: E885-E894.
    • (2013) Am J Physiol Endocrinol Metab , vol.304
    • Gburcik, V.1    Cleasby, M.E.2    Timmons, J.A.3
  • 22
    • 79960044661 scopus 로고    scopus 로고
    • Atrial natriuretic peptide regulates lipid mobilization and oxygen consumption in human adipocytes by activating AMPK
    • Souza SC, Chau MD, Yang Q, et al. Atrial natriuretic peptide regulates lipid mobilization and oxygen consumption in human adipocytes by activating AMPK. Biochem Biophys Res Commun 2011; 410: 398-403.
    • (2011) Biochem Biophys Res Commun , vol.410 , pp. 398-403
    • Souza, S.C.1    Chau, M.D.2    Yang, Q.3
  • 23
    • 65349152290 scopus 로고    scopus 로고
    • Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: Novel mechanisms integrating HSL and ATGL
    • Gaidhu MP, Fediuc S, Anthony NM, et al. Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: novel mechanisms integrating HSL and ATGL. J Lipid Res 2009; 50: 704-715.
    • (2009) J Lipid Res , vol.50 , pp. 704-715
    • Gaidhu, M.P.1    Fediuc, S.2    Anthony, N.M.3
  • 24
    • 73649128543 scopus 로고    scopus 로고
    • AMPK beta1 deletion reduces appetite, preventing obesity and hepatic insulin resistance
    • Dzamko N, van Denderen BJ, Hevener AL, et al. AMPK beta1 deletion reduces appetite, preventing obesity and hepatic insulin resistance. J Biol Chem 2010; 285: 115-122.
    • (2010) J Biol Chem , vol.285 , pp. 115-122
    • Dzamko, N.1    Van Denderen, B.J.2    Hevener, A.L.3
  • 25
    • 84880746018 scopus 로고    scopus 로고
    • Acute Exercise induces p53 translocation to the mitochondria and promotes a p53-Tfam-mtDNA complex in skeletal muscle
    • Saleem A, Hood DA,. Acute Exercise induces p53 translocation to the mitochondria and promotes a p53-Tfam-mtDNA complex in skeletal muscle. J Physiol 2013; 591: 3625-3636.
    • (2013) J Physiol , vol.591 , pp. 3625-3636
    • Saleem, A.1    Hood, D.A.2
  • 26
    • 84856273971 scopus 로고    scopus 로고
    • Epinephrine induces PDK4 mRNA expression in adipose tissue from obese, insulin resistant rats
    • Wan Z, Frier BC, Williams DB, Wright DC,. Epinephrine induces PDK4 mRNA expression in adipose tissue from obese, insulin resistant rats. Obesity (Silver Spring) 2012; 20: 453-456.
    • (2012) Obesity (Silver Spring) , vol.20 , pp. 453-456
    • Wan, Z.1    Frier, B.C.2    Williams, D.B.3    Wright, D.C.4
  • 27
    • 84864210982 scopus 로고    scopus 로고
    • 6 Indirectly modulates the induction of glyceroneogenic enzymes in adipose tissue during exercise
    • Wan Z, Ritchie I, Beaudoin MS, Castellani L, Chan CB, Wright DC. IL-, 6 Indirectly modulates the induction of glyceroneogenic enzymes in adipose tissue during exercise. PLoS One 2012; 7: e41719.
    • (2012) PLoS One , vol.7
    • Wan, Z.1    Ritchie, I.2    Beaudoin, M.S.3    Castellani, L.4    Chan, C.B.5    Wright, D.C.I.6
  • 28
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD,. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 29
    • 78549272729 scopus 로고    scopus 로고
    • Whole body deletion of AMP-activated protein kinase {beta}2 reduces muscle AMPK activity and exercise capacity
    • Steinberg GR, O'Neill HM, Dzamko NL, et al. Whole body deletion of AMP-activated protein kinase {beta}2 reduces muscle AMPK activity and exercise capacity. J Biol Chem 2010; 285: 37198-37209.
    • (2010) J Biol Chem , vol.285 , pp. 37198-37209
    • Steinberg, G.R.1    O'Neill, H.M.2    Dzamko, N.L.3
  • 30
    • 80053163909 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise
    • O'Neill HM, Maarbjerg SJ, Crane JD, et al. AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise. Proc Natl Acad Sci U S A 2011; 108: 16092-16097.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 16092-16097
    • O'Neill, H.M.1    Maarbjerg, S.J.2    Crane, J.D.3
  • 31
    • 0018572576 scopus 로고
    • Regional differences and effect of weight reduction on human fat cell metabolism
    • Smith U, Hammersten J, Bjorntorp P, Kral JG,. Regional differences and effect of weight reduction on human fat cell metabolism. Eur J Clin Invest 1979; 9: 327-332.
    • (1979) Eur J Clin Invest , vol.9 , pp. 327-332
    • Smith, U.1    Hammersten, J.2    Bjorntorp, P.3    Kral, J.G.4
  • 32
    • 0017570257 scopus 로고
    • Human fat cell adenylate cyclase: Regional differences in adrenaline responsiveness
    • Kather H, Zollig K, Simon B, Schlierf G,. Human fat cell adenylate cyclase: regional differences in adrenaline responsiveness. Eur J Clin Invest 1977; 7: 595-597.
    • (1977) Eur J Clin Invest , vol.7 , pp. 595-597
    • Kather, H.1    Zollig, K.2    Simon, B.3    Schlierf, G.4
  • 33
    • 84862776702 scopus 로고    scopus 로고
    • A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
    • Bostrom P, Wu J, Jedrychowski MP, et al. A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 2012; 481: 463-468.
    • (2012) Nature , vol.481 , pp. 463-468
    • Bostrom, P.1    Wu, J.2    Jedrychowski, M.P.3
  • 34
    • 84859412650 scopus 로고    scopus 로고
    • Insulin sensitive and resistant obesity in humans: AMPK activity, oxidative stress, and depot-specific changes in gene expression in adipose tissue
    • Xu XJ, Gauthier MS, Hess DT, et al. Insulin sensitive and resistant obesity in humans: AMPK activity, oxidative stress, and depot-specific changes in gene expression in adipose tissue. J Lipid Res 2012; 53: 792-801.
    • (2012) J Lipid Res , vol.53 , pp. 792-801
    • Xu, X.J.1    Gauthier, M.S.2    Hess, D.T.3
  • 35
    • 33845864967 scopus 로고    scopus 로고
    • Adipocytes as regulators of energy balance and glucose homeostasis
    • Rosen ED, Spiegelman BM,. Adipocytes as regulators of energy balance and glucose homeostasis. Nature 2006; 444: 847-853.
    • (2006) Nature , vol.444 , pp. 847-853
    • Rosen, E.D.1    Spiegelman, B.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.