Intracellular fatty acids suppress β-adrenergic induction of PKA-targeted gene expression in white adipocytes

American Journal of Physiology - Endocrinology and Metabolism

Volumn 301, Issue 1, 2011, Pages

  Mottillo, Emilio P ^a   Granneman, James G ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine 3',5' cyclic monophosphate; Adenylyl cyclase; Adipose tissue; Adipose triglyceride lipase; Hormone sensitive lipase; Protein kinase A

Indexed keywords

5 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1,3 BENZODIOXOLE 2,2 DICARBOXYLIC ACID; ADENYLATE CYCLASE; BETA 3 ADRENERGIC RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; FATTY ACID; HORMONE SENSITIVE LIPASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SMALL INTERFERING RNA; UNCOUPLING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BETA ADRENERGIC STIMULATION; CELL NUCLEUS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME INHIBITION; FATTY ACID TRANSPORT; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; GENE SILENCING; INTRACELLULAR SPACE; LIPOLYSIS; MALE; MITOCHONDRION; MOUSE; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION; WHITE ADIPOSE TISSUE; WILD TYPE;

3T3-L1 CELLS; ADIPOCYTES, WHITE; ANIMALS; COENZYME A LIGASES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOWN-REGULATION; ENZYME INHIBITORS; FATTY ACIDS; FEMALE; GENE EXPRESSION; INTRACELLULAR SPACE; LIPOLYSIS; MALE; MICE; MICE, INBRED C57BL; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, ADRENERGIC, BETA-3; TRIAZENES;

EID: 79959601726     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00039.2011     Document Type: Article

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