Human stem cell aging: Do mitochondrial DNA mutations have a causal role?

Aging Cell

Volumn 13, Issue 2, 2014, Pages 201-205

  Baines, Holly L ^a   Turnbull, Douglass M ^a,b   Greaves, Laura C ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Aging; Human; Mitochondria; Mutator mouse; Stem cells

Indexed keywords

CYTOCHROME C OXIDASE; DNA DIRECTED DNA POLYMERASE GAMMA; MITOCHONDRIAL DNA;

CELL AGING; CELL DAMAGE; CELL DEATH; CELL FUNCTION; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; MITOCHONDRION; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; POINT MUTATION; POPULATION; PREMATURE AGING; PRIORITY JOURNAL; RESPIRATORY CHAIN; REVIEW; SOMATIC MUTATION; STEM CELL;

MUS;

AGING; HUMAN; MITOCHONDRIA; MUTATOR MOUSE; STEM CELLS;

ANIMALS; CELL AGING; DNA, MITOCHONDRIAL; HUMANS; MITOSIS; MODELS, ANIMAL; MUTATION; STEM CELLS;

EID: 84895788635     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12199     Document Type: Review

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