Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress

EMBO Molecular Medicine

Volumn 6, Issue 3, 2014, Pages 335-346

  Hosoi, Toru ^a   Yamaguchi, Rie ^a   Noji, Kikuko ^a   Matsuo, Suguru ^a   Baba, Sachiko ^a   Toyoda, Keisuke ^a   Suezawa, Takahiro ^a   Kayano, Takaaki ^a   Tanaka, Shinpei ^b   Ozawa, Koichiro ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Aldehyde dehydrogenase; Nonsteroidal anti inflammatory drug; STAT3

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 2; ALPHA LACTALBUMIN; ANTIOBESITY AGENT; CHAPERONE; FLURBIPROFEN; LEPTIN; MELOXICAM; NONSTEROID ANTIINFLAMMATORY AGENT; RECOMBINANT LEPTIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL STRAIN HEK293; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG TARGETING; ENDOPLASMIC RETICULUM STRESS; FEMALE; HORMONE RESISTANCE; HUMAN; HUMAN CELL; LIPID DIET; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN AGGREGATION; UNFOLDED PROTEIN RESPONSE;

ALDEHYDE DEHYDROGENASE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; DIET, HIGH-FAT; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FLURBIPROFEN; HEK293 CELLS; HUMANS; LEPTIN; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; OBESITY; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84895742693     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201303227     Document Type: Article

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