B-cell receptor configuration and mutational analysis of patients with chronic lymphocytic leukaemia and trisomy 12 reveal recurrent molecular abnormalities

Hematological Oncology

Volumn 32, Issue 1, 2014, Pages 22-30

  Falisi, Erika ^a   Novella, Elisabetta ^a   Visco, Carlo ^a   Guercini, Nicola ^a   Maura, Francesco ^b   Giaretta, Ilaria ^a   Pomponi, Fabrizio ^a   Nichele, Ilaria ^a   Finotto, Silvia ^a   Montaldi, Annamaria ^a   Neri, Antonino ^b   Rodeghiero, Francesco ^a  

^a SAN BORTOLO HOSPITAL   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Chronic lymphocytic leukaemia; FBXW7; NOTCH1; Stereotyped BCR; TP53

Indexed keywords

B LYMPHOCYTE RECEPTOR; NOTCH1 RECEPTOR; PROTEIN P53;

ADULT; AGED; APOPTOSIS; ARTICLE; CANCER PROGNOSIS; CELL PROLIFERATION; CHROMOSOME 12; CHROMOSOME ANALYSIS; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; FBXW7 GENE; FEMALE; FRAMESHIFT MUTATION; GENE; GENE MUTATION; HUMAN; IGHV4 GENE; KARYOTYPE; MALE; MALIGNANT TRANSFORMATION; MIDDLE AGED; MISSENSE MUTATION; MUTATIONAL ANALYSIS; NOTCH1 RECEPTOR GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN P53 GENE; RICHTER SYNDROME; STEREOTYPY; TRISOMY 12; TUMOR ESCAPE;

CHRONIC LYMPHOCYTIC LEUKAEMIA; FBXW7; NOTCH1; STEREOTYPED BCR; TP53;

AGED; AMINO ACID SEQUENCE; ANIMALS; CELL CYCLE PROTEINS; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOMES, HUMAN, PAIR 12; CLONE CELLS; CONSERVED SEQUENCE; DISEASE PROGRESSION; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; F-BOX PROTEINS; FEMALE; GENE REARRANGEMENT, B-LYMPHOCYTE; GENE REARRANGEMENT, B-LYMPHOCYTE, HEAVY CHAIN; GENES, IMMUNOGLOBULIN; GENES, P53; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTERPHASE; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASTIC STEM CELLS; RECEPTOR, NOTCH1; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; SYNDROME; TRISOMY; UBIQUITIN-PROTEIN LIGASES;

EID: 84895561052     PISSN: 02780232     EISSN: 10991069     Source Type: Journal    
DOI: 10.1002/hon.2086     Document Type: Article

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