-
3
-
-
34548138938
-
The role of prognostic factors in assessing 'high-risk' subgroups of patients with chronic lymphocytic leukemia
-
Kay NE, O'Brien SM, Pettitt AR, Stilgenbauer S, (2007) The role of prognostic factors in assessing 'high-risk' subgroups of patients with chronic lymphocytic leukemia. Leukemia 21: 1885-1891.
-
(2007)
Leukemia
, vol.21
, pp. 1885-1891
-
-
Kay, N.E.1
O'Brien, S.M.2
Pettitt, A.R.3
Stilgenbauer, S.4
-
4
-
-
27244434788
-
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
-
Calin GA, Ferracin M, Cimmino A, Di LG, Shimizu M, et al. (2005) A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med 353: 1793-1801.
-
(2005)
N Engl J Med
, vol.353
, pp. 1793-1801
-
-
Calin, G.A.1
Ferracin, M.2
Cimmino, A.3
Di, L.G.4
Shimizu, M.5
-
5
-
-
0034727833
-
Genomic aberrations and survival in chronic lymphocytic leukemia
-
Dohner H, Stilgenbauer S, Benner A, Leupolt E, Krober A, et al. (2000) Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med 343: 1910-1916.
-
(2000)
N Engl J Med
, vol.343
, pp. 1910-1916
-
-
Dohner, H.1
Stilgenbauer, S.2
Benner, A.3
Leupolt, E.4
Krober, A.5
-
6
-
-
72949093335
-
From pathogenesis to treatment of chronic lymphocytic leukaemia
-
Zenz T, Mertens D, Kuppers R, Dohner H, Stilgenbauer S, (2010) From pathogenesis to treatment of chronic lymphocytic leukaemia. Nat Rev Cancer 10: 37-50.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 37-50
-
-
Zenz, T.1
Mertens, D.2
Kuppers, R.3
Dohner, H.4
Stilgenbauer, S.5
-
7
-
-
36148992239
-
CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cells
-
Damle RN, Temburni S, Calissano C, Yancopoulos S, Banapour T, et al. (2007) CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cells. Blood 110: 3352-3359.
-
(2007)
Blood
, vol.110
, pp. 3352-3359
-
-
Damle, R.N.1
Temburni, S.2
Calissano, C.3
Yancopoulos, S.4
Banapour, T.5
-
8
-
-
0033567907
-
Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
-
Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK, (1999) Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 94: 1848-1854.
-
(1999)
Blood
, vol.94
, pp. 1848-1854
-
-
Hamblin, T.J.1
Davis, Z.2
Gardiner, A.3
Oscier, D.G.4
Stevenson, F.K.5
-
9
-
-
0032532668
-
Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors
-
Fais F, Ghiotto F, Hashimoto S, Sellars B, Valetto A, et al. (1998) Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors. J Clin Invest 102: 1515-1525.
-
(1998)
J Clin Invest
, vol.102
, pp. 1515-1525
-
-
Fais, F.1
Ghiotto, F.2
Hashimoto, S.3
Sellars, B.4
Valetto, A.5
-
10
-
-
33846108722
-
Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations
-
Stamatopoulos K, Belessi C, Moreno C, Boudjograh M, Guida G, et al. (2007) Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations. Blood 109: 259-270.
-
(2007)
Blood
, vol.109
, pp. 259-270
-
-
Stamatopoulos, K.1
Belessi, C.2
Moreno, C.3
Boudjograh, M.4
Guida, G.5
-
11
-
-
10744230550
-
Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: implicating recognition of a common antigen epitope
-
Tobin G, Thunberg U, Johnson A, Eriksson I, Soderberg O, et al. (2003) Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: implicating recognition of a common antigen epitope. Blood 101: 4952-4957.
-
(2003)
Blood
, vol.101
, pp. 4952-4957
-
-
Tobin, G.1
Thunberg, U.2
Johnson, A.3
Eriksson, I.4
Soderberg, O.5
-
12
-
-
4944244255
-
Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins
-
Widhopf GF, Rassenti LZ, Toy TL, Gribben JG, Wierda WG, et al. (2004) Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins. Blood 104: 2499-2504.
-
(2004)
Blood
, vol.104
, pp. 2499-2504
-
-
Widhopf, G.F.1
Rassenti, L.Z.2
Toy, T.L.3
Gribben, J.G.4
Wierda, W.G.5
-
13
-
-
33947598891
-
Comprehensive characterization of IGHV3-21-expressing B-cell chronic lymphocytic leukemia: an Italian multicenter study
-
Bomben R, Dal BM, Capello D, Benedetti D, Marconi D, et al. (2007) Comprehensive characterization of IGHV3-21-expressing B-cell chronic lymphocytic leukemia: an Italian multicenter study. Blood 109: 2989-2998.
-
(2007)
Blood
, vol.109
, pp. 2989-2998
-
-
Bomben, R.1
Dal, B.M.2
Capello, D.3
Benedetti, D.4
Marconi, D.5
-
14
-
-
79951498701
-
Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities
-
Chiorazzi N, Ferrarini M, (2011) Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities. Blood 117: 1781-1791.
-
(2011)
Blood
, vol.117
, pp. 1781-1791
-
-
Chiorazzi, N.1
Ferrarini, M.2
-
15
-
-
78649792807
-
The role of the B-cell receptor in the pathogenesis of chronic lymphocytic leukaemia
-
Packham G, Stevenson F, (2010) The role of the B-cell receptor in the pathogenesis of chronic lymphocytic leukaemia. Semin Cancer Biol 20: 391-399.
-
(2010)
Semin Cancer Biol
, vol.20
, pp. 391-399
-
-
Packham, G.1
Stevenson, F.2
-
16
-
-
7244232709
-
Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia
-
Tobin G, Thunberg U, Karlsson K, Murray F, Laurell A, et al. (2004) Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia. Blood 104: 2879-2885.
-
(2004)
Blood
, vol.104
, pp. 2879-2885
-
-
Tobin, G.1
Thunberg, U.2
Karlsson, K.3
Murray, F.4
Laurell, A.5
-
17
-
-
40849084172
-
Recurrent cytogenetic findings in subsets of patients with chronic lymphocytic leukemia expressing IgG-switched stereotyped immunoglobulins 21
-
Athanasiadou A, Stamatopoulos K, Gaitatzi M, Stavroyianni N, Fassas A, et al. (2008) Recurrent cytogenetic findings in subsets of patients with chronic lymphocytic leukemia expressing IgG-switched stereotyped immunoglobulins 21. Haematologica 93: 473-474.
-
(2008)
Haematologica
, vol.93
, pp. 473-474
-
-
Athanasiadou, A.1
Stamatopoulos, K.2
Gaitatzi, M.3
Stavroyianni, N.4
Fassas, A.5
-
18
-
-
77956865697
-
High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with 'stereotyped' IGHV3-21 and IGHV4-34 B-cell receptors
-
Marincevic M, Cahill N, Gunnarsson R, Isaksson A, Mansouri M, et al. (2010) High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with 'stereotyped' IGHV3-21 and IGHV4-34 B-cell receptors. Haematologica 95: 1519-1525.
-
(2010)
Haematologica
, vol.95
, pp. 1519-1525
-
-
Marincevic, M.1
Cahill, N.2
Gunnarsson, R.3
Isaksson, A.4
Mansouri, M.5
-
19
-
-
13544275555
-
Geographic patterns and pathogenetic implications of IGHV gene usage in chronic lymphocytic leukemia: the lesson of the IGHV3-21 gene
-
Ghia P, Stamatopoulos K, Belessi C, Moreno C, Stella S, et al. (2005) Geographic patterns and pathogenetic implications of IGHV gene usage in chronic lymphocytic leukemia: the lesson of the IGHV3-21 gene. Blood 105: 1678-1685.
-
(2005)
Blood
, vol.105
, pp. 1678-1685
-
-
Ghia, P.1
Stamatopoulos, K.2
Belessi, C.3
Moreno, C.4
Stella, S.5
-
20
-
-
67650393955
-
Stereotyped B-cell receptor is an independent risk factor of chronic lymphocytic leukemia transformation to Richter syndrome
-
Rossi D, Spina V, Cerri M, Rasi S, Deambrogi C, et al. (2009) Stereotyped B-cell receptor is an independent risk factor of chronic lymphocytic leukemia transformation to Richter syndrome. Clin Cancer Res 15: 4415-4422.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4415-4422
-
-
Rossi, D.1
Spina, V.2
Cerri, M.3
Rasi, S.4
Deambrogi, C.5
-
21
-
-
4344704897
-
Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia
-
Messmer BT, Albesiano E, Efremov DG, Ghiotto F, Allen SL, et al. (2004) Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia. J Exp Med 200: 519-525.
-
(2004)
J Exp Med
, vol.200
, pp. 519-525
-
-
Messmer, B.T.1
Albesiano, E.2
Efremov, D.G.3
Ghiotto, F.4
Allen, S.L.5
-
22
-
-
58549100059
-
Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: results from an Italian multicentre study
-
Bomben R, Dal BM, Capello D, Forconi F, Maffei R, et al. (2009) Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: results from an Italian multicentre study. Br J Haematol 144: 492-506.
-
(2009)
Br J Haematol
, vol.144
, pp. 492-506
-
-
Bomben, R.1
Dal, B.M.2
Capello, D.3
Forconi, F.4
Maffei, R.5
-
23
-
-
38949203770
-
Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis
-
Murray F, Darzentas N, Hadzidimitriou A, Tobin G, Boudjogra M, et al. (2008) Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis. Blood 111: 1524-1533.
-
(2008)
Blood
, vol.111
, pp. 1524-1533
-
-
Murray, F.1
Darzentas, N.2
Hadzidimitriou, A.3
Tobin, G.4
Boudjogra, M.5
-
24
-
-
45149100665
-
Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
-
Hallek M, Cheson BD, Catovsky D, Caligaris-Cappio F, Dighiero G, et al. (2008) Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood 111: 5446-5456.
-
(2008)
Blood
, vol.111
, pp. 5446-5456
-
-
Hallek, M.1
Cheson, B.D.2
Catovsky, D.3
Caligaris-Cappio, F.4
Dighiero, G.5
-
25
-
-
0037406968
-
ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia
-
Crespo M, Bosch F, Villamor N, Bellosillo B, Colomer D, et al. (2003) ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia. N Engl J Med 348: 1764-1775.
-
(2003)
N Engl J Med
, vol.348
, pp. 1764-1775
-
-
Crespo, M.1
Bosch, F.2
Villamor, N.3
Bellosillo, B.4
Colomer, D.5
-
26
-
-
40849113676
-
Clonal heterogeneity in chronic lymphocytic leukemia cells: superior response to surface IgM cross-linking in CD38, ZAP-70-positive cells
-
Cutrona G, Colombo M, Matis S, Fabbi M, Spriano M, et al. (2008) Clonal heterogeneity in chronic lymphocytic leukemia cells: superior response to surface IgM cross-linking in CD38, ZAP-70-positive cells. Haematologica 93: 413-422.
-
(2008)
Haematologica
, vol.93
, pp. 413-422
-
-
Cutrona, G.1
Colombo, M.2
Matis, S.3
Fabbi, M.4
Spriano, M.5
-
27
-
-
4143105617
-
ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia
-
Rassenti LZ, Huynh L, Toy TL, Chen L, Keating MJ, et al. (2004) ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia. N Engl J Med 351: 893-901.
-
(2004)
N Engl J Med
, vol.351
, pp. 893-901
-
-
Rassenti, L.Z.1
Huynh, L.2
Toy, T.L.3
Chen, L.4
Keating, M.J.5
-
28
-
-
48249129741
-
Molecular and transcriptional characterization of 17p loss in B-cell chronic lymphocytic leukemia
-
Fabris S, Mosca L, Todoerti K, Cutrona G, Lionetti M, et al. (2008) Molecular and transcriptional characterization of 17p loss in B-cell chronic lymphocytic leukemia. Genes Chromosomes Cancer 47: 781-793.
-
(2008)
Genes Chromosomes Cancer
, vol.47
, pp. 781-793
-
-
Fabris, S.1
Mosca, L.2
Todoerti, K.3
Cutrona, G.4
Lionetti, M.5
-
29
-
-
74949107027
-
The normal IGHV1-69-derived B-cell repertoire contains stereotypic patterns characteristic of unmutated CLL
-
Forconi F, Potter KN, Wheatley I, Darzentas N, Sozzi E, et al. (2010) The normal IGHV1-69-derived B-cell repertoire contains stereotypic patterns characteristic of unmutated CLL. Blood 115: 71-77.
-
(2010)
Blood
, vol.115
, pp. 71-77
-
-
Forconi, F.1
Potter, K.N.2
Wheatley, I.3
Darzentas, N.4
Sozzi, E.5
-
30
-
-
0014757386
-
A general method applicable to the search for similarities in the amino acid sequence of two proteins
-
Needleman SB, Wunsch CD, (1970) A general method applicable to the search for similarities in the amino acid sequence of two proteins. J Mol Biol 48: 443-453.
-
(1970)
J Mol Biol
, vol.48
, pp. 443-453
-
-
Needleman, S.B.1
Wunsch, C.D.2
-
31
-
-
0026458378
-
Amino acid substitution matrices from protein blocks
-
Henikoff S, Henikoff JG, (1992) Amino acid substitution matrices from protein blocks. Proc Natl Acad Sci U S A 89: 10915-10919.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 10915-10919
-
-
Henikoff, S.1
Henikoff, J.G.2
-
32
-
-
1542532754
-
A proportional hazards model for the subdistribution of a competing risk
-
Fine JP, Gray RJ, (1999) A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc 94: 496-509.
-
(1999)
J Am Stat Assoc
, vol.94
, pp. 496-509
-
-
Fine, J.P.1
Gray, R.J.2
|