The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for notch signaling

Cancer Research

Volumn 67, Issue 12, 2007, Pages 5611-5616

  Malyukova, Alena ^a   Dohda, Takeaki ^b   Von Der Lehr, Natalie ^a   Akhondi, Shahab ^a,d   Corcoran, Martin ^a   Heyman, Mats ^a   Spruck, Charles ^c   Grandér, Dan ^a   Lendahl, Urban ^b   Sangfelt, Olle ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c SIDNEY KIMMEL CANCER CENTER   (United States)

^d SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; F BOX PROTEIN; NOTCH1 RECEPTOR; PROTEIN HCDC4; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CANCER SURVIVAL; CONTROLLED STUDY; ENZYME SUBSTRATE COMPLEX; FEMALE; GENE MUTATION; HALF LIFE TIME; HUMAN; HUMAN CELL; LEUKEMIA CELL; LEUKEMOGENESIS; MALE; MISSENSE MUTATION; PRIORITY JOURNAL; SCHOOL CHILD; SIGNAL TRANSDUCTION; T CELL LEUKEMIA; TUMOR SUPPRESSOR GENE; UBIQUITINATION; WILD TYPE;

BASE SEQUENCE; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CHILD; DNA MUTATIONAL ANALYSIS; F-BOX PROTEINS; FEMALE; HUMANS; LEUKEMIA, T-CELL, ACUTE; MALE; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES;

EID: 34250837539     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-4381     Document Type: Article

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