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Volumn 5 FEB, Issue , 2014, Pages

Effects of cannabinoid drugs on the deficit of prepulse inhibition of startle in an animal model of schizophrenia: The SHR strain

Author keywords

Animal model; Cannabinoid drugs; PPI; Schizophrenia; SHR

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABIDIOL; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR AFFECTING AGENT; ENDOCANNABINOID; N (4 HYDROXYPHENYL)ARACHIDONAMIDE; RIMONABANT;

EID: 84895529159     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2014.00010     Document Type: Article
Times cited : (63)

References (118)
  • 1
    • 0032914945 scopus 로고    scopus 로고
    • Blockade of cannabinoid receptors by SR141716 selectively increases Fos expression in rat mesocorticolimbic areas via reduced dopamine D2 function
    • doi: 10.1016/S0306-4522(98)00675-7
    • Alonso, R., Voutsinos, B., Fournier, M., Labie, C., Steinberg, R., Souilhac, J., et al. (1999). Blockade of cannabinoid receptors by SR141716 selectively increases Fos expression in rat mesocorticolimbic areas via reduced dopamine D2 function. Neuroscience 91, 607-620. doi: 10.1016/S0306-4522(98)00675-7.
    • (1999) Neuroscience , vol.91 , pp. 607-620
    • Alonso, R.1    Voutsinos, B.2    Fournier, M.3    Labie, C.4    Steinberg, R.5    Souilhac, J.6
  • 2
    • 34548666018 scopus 로고    scopus 로고
    • Cannabinoid receptor antagonists counteract sensorimotor gating deficits in the phencyclidine model of psychosis
    • doi: 10.1038/sj.npp.1301344
    • Ballmaier, M., Bortolato, M., Rizzetti, C., Zoli, M., Gessa, G., Heinz, A., et al. (2007). Cannabinoid receptor antagonists counteract sensorimotor gating deficits in the phencyclidine model of psychosis. Neuropsychopharmacology 32, 2098-2107. doi: 10.1038/sj.npp.1301344.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 2098-2107
    • Ballmaier, M.1    Bortolato, M.2    Rizzetti, C.3    Zoli, M.4    Gessa, G.5    Heinz, A.6
  • 4
    • 83455262550 scopus 로고    scopus 로고
    • Safety and side effects of cannabidiol, a Cannabis sativa constituent
    • doi: 10.2174/157488611798280924
    • Bergamaschi, M. M., Queiroz, R. H., Zuardi, A. W., and Crippa, J. A. (2011). Safety and side effects of cannabidiol, a Cannabis sativa constituent. Curr. Drug Saf. 6, 237-249. doi: 10.2174/157488611798280924.
    • (2011) Curr. Drug Saf. , vol.6 , pp. 237-249
    • Bergamaschi, M.M.1    Queiroz, R.H.2    Zuardi, A.W.3    Crippa, J.A.4
  • 5
    • 0036920082 scopus 로고    scopus 로고
    • Cannabis and schizophrenia: impact on onset, course, psychopathology and outcomes
    • doi: 10.1007/s00406-002-0366-5
    • Bersani, G., Orlandi, V., Kotzalidis, G. D., and Pancheri, P. (2002). Cannabis and schizophrenia: impact on onset, course, psychopathology and outcomes. Eur. Arch. Psychiatry Clin. Neurosci. 252, 86-92. doi: 10.1007/s00406-002-0366-5.
    • (2002) Eur. Arch. Psychiatry Clin. Neurosci. , vol.252 , pp. 86-92
    • Bersani, G.1    Orlandi, V.2    Kotzalidis, G.D.3    Pancheri, P.4
  • 6
    • 64849106877 scopus 로고    scopus 로고
    • Modulation of mediotemporal and ventrostriatal function in humans by Δ 9-tetrahydrocannabinol: a neural basis for the effects of Cannabis sativa on learning and psychosis
    • doi: 10.1001/archgenpsychiatry.2009.17
    • Bhattacharyya, S., Fusar-Poli, P., Borgwardt, S., Martin-Santos, R., Nosarti, C., O'Carroll, C., et al. (2009). Modulation of mediotemporal and ventrostriatal function in humans by Δ 9-tetrahydrocannabinol: a neural basis for the effects of Cannabis sativa on learning and psychosis. Arch. Gen. Psychiatry 66, 442-451. doi: 10.1001/archgenpsychiatry.2009.17.
    • (2009) Arch. Gen. Psychiatry , vol.66 , pp. 442-451
    • Bhattacharyya, S.1    Fusar-Poli, P.2    Borgwardt, S.3    Martin-Santos, R.4    Nosarti, C.5    O'Carroll, C.6
  • 7
    • 75749126485 scopus 로고    scopus 로고
    • Opposite effects of Δ-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathology
    • doi: 10.1038/npp.2009.184
    • Bhattacharyya, S., Morrison, P. D., Fusar-Poli, P., Martin-Santos, R., Borgwardt, S., Winton-Brown, T., et al. (2010). Opposite effects of Δ-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathology. Neuropsychopharmacology 35, 764-774. doi: 10.1038/npp.2009.184.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 764-774
    • Bhattacharyya, S.1    Morrison, P.D.2    Fusar-Poli, P.3    Martin-Santos, R.4    Borgwardt, S.5    Winton-Brown, T.6
  • 8
    • 0034751335 scopus 로고    scopus 로고
    • Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide
    • doi: 10.1038/sj.bjp.0704327
    • Bisogno, T., Hanus, L., De Petrocellis, L., Tchilibon, S., Ponde, D. E., Brandi, I., et al. (2001). Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. Br. J. Pharmacol. 134, 845-852. doi: 10.1038/sj.bjp.0704327.
    • (2001) Br. J. Pharmacol. , vol.134 , pp. 845-852
    • Bisogno, T.1    Hanus, L.2    De Petrocellis, L.3    Tchilibon, S.4    Ponde, D.E.5    Brandi, I.6
  • 9
    • 34347386847 scopus 로고    scopus 로고
    • Methylphenidate reduces impulsive behaviour in juvenile Wistar rats, but not in adult Wistar, SHR and WKY rats
    • doi: 10.1007/s00213-007-0781-4
    • Bizot, J. C., Chenault, N., Houze, B., Herpin, A., David, S., Pothion, S., et al. (2007). Methylphenidate reduces impulsive behaviour in juvenile Wistar rats, but not in adult Wistar, SHR and WKY rats. Psychopharmacology (Berl.) 193, 215-223. doi: 10.1007/s00213-007-0781-4.
    • (2007) Psychopharmacology (Berl.) , vol.193 , pp. 215-223
    • Bizot, J.C.1    Chenault, N.2    Houze, B.3    Herpin, A.4    David, S.5    Pothion, S.6
  • 10
    • 79954988963 scopus 로고    scopus 로고
    • AVE1625, a cannabinoid CB1 receptor antagonist, as a co-treatment with antipsychotics for schizophrenia: improvement in cognitive function and reduction of antipsychotic-side effects in rodents
    • doi: 10.1007/s00213-010-2124-0
    • Black, M. D., Stevens, R. J., Rogacki, N., Featherstone, R. E., Senyah, Y., Giardino, O., et al. (2011). AVE1625, a cannabinoid CB1 receptor antagonist, as a co-treatment with antipsychotics for schizophrenia: improvement in cognitive function and reduction of antipsychotic-side effects in rodents. Psychopharmacology (Berl.) 215, 149-163. doi: 10.1007/s00213-010-2124-0.
    • (2011) Psychopharmacology (Berl.) , vol.215 , pp. 149-163
    • Black, M.D.1    Stevens, R.J.2    Rogacki, N.3    Featherstone, R.E.4    Senyah, Y.5    Giardino, O.6
  • 11
    • 55349114694 scopus 로고    scopus 로고
    • Neural basis of Δ-9-tetrahydrocannabinol and cannabidiol: effects during response inhibition
    • doi: 10.1016/j.biopsych.2008.05.011
    • Borgwardt, S. J., Allen, P., Bhattacharyya, S., Fusar-Poli, P., Crippa, J. A., Seal, M. L., et al. (2008). Neural basis of Δ-9-tetrahydrocannabinol and cannabidiol: effects during response inhibition. Biol. Psychiatry 64, 966-973. doi: 10.1016/j.biopsych.2008.05.011.
    • (2008) Biol. Psychiatry , vol.64 , pp. 966-973
    • Borgwardt, S.J.1    Allen, P.2    Bhattacharyya, S.3    Fusar-Poli, P.4    Crippa, J.A.5    Seal, M.L.6
  • 12
    • 33746149921 scopus 로고    scopus 로고
    • Anxiolytic-like properties of the anandamide transport inhibitor AM404
    • doi: 10.1038/sj.npp.1301061
    • Bortolato, M., Campolongo, P., Mangieri, R. A., Scattoni, M. L., Frau, R., Trezza, V., et al. (2006). Anxiolytic-like properties of the anandamide transport inhibitor AM404. Neuropsychopharmacology 31, 2652-2659. doi: 10.1038/sj.npp.1301061.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2652-2659
    • Bortolato, M.1    Campolongo, P.2    Mangieri, R.A.3    Scattoni, M.L.4    Frau, R.5    Trezza, V.6
  • 13
    • 0025190458 scopus 로고
    • Sensorimotor gating and schizophrenia. Human and animal model studies
    • doi: 10.1001/archpsyc.1990.01810140081011
    • Braff, D. L., and Geyer, M. A. (1990). Sensorimotor gating and schizophrenia. Human and animal model studies. Arch. Gen. Psychiatry 47, 181-188. doi: 10.1001/archpsyc.1990.01810140081011.
    • (1990) Arch. Gen. Psychiatry , vol.47 , pp. 181-188
    • Braff, D.L.1    Geyer, M.A.2
  • 14
    • 0026581360 scopus 로고
    • Gating and habituation of the startle reflex in schizophrenic patients
    • doi: 10.1001/archpsyc.1992.01820030038005
    • Braff, D. L., Grillon, C., and Geyer, M. A. (1992). Gating and habituation of the startle reflex in schizophrenic patients. Arch. Gen. Psychiatry 49, 206-215. doi: 10.1001/archpsyc.1992.01820030038005.
    • (1992) Arch. Gen. Psychiatry , vol.49 , pp. 206-215
    • Braff, D.L.1    Grillon, C.2    Geyer, M.A.3
  • 15
    • 0032908295 scopus 로고    scopus 로고
    • Symptom correlates of prepulse inhibition deficits in male schizophrenic patients
    • Braff, D. L., Swerdlow, N. R., and Geyer, M. A. (1999). Symptom correlates of prepulse inhibition deficits in male schizophrenic patients. Am. J. Psychiatry 156, 596-602.
    • (1999) Am. J. Psychiatry , vol.156 , pp. 596-602
    • Braff, D.L.1    Swerdlow, N.R.2    Geyer, M.A.3
  • 16
    • 79151480737 scopus 로고    scopus 로고
    • Acute treatment with cannabinoid receptor agonist WIN55212.2 improves prepulse inhibition in psychosocially stressed mice
    • doi: 10.1016/j.bbr.2010.11.003
    • Brzozka, M. M., Fischer, A., Falkai, P., and Havemann-Reinecke, U. (2011). Acute treatment with cannabinoid receptor agonist WIN55212.2 improves prepulse inhibition in psychosocially stressed mice. Behav. Brain Res. 218, 280-287. doi: 10.1016/j.bbr.2010.11.003.
    • (2011) Behav. Brain Res. , vol.218 , pp. 280-287
    • Brzozka, M.M.1    Fischer, A.2    Falkai, P.3    Havemann-Reinecke, U.4
  • 17
    • 79960321395 scopus 로고    scopus 로고
    • Effects of antipsychotics and amphetamine on social behaviors in spontaneously hypertensive rats
    • doi: 10.1016/j.bbr.2011.06.026
    • Calzavara, M. B., Levin, R., Medrano, W. A., Almeida, V., Sampaio, A. P., Barone, L. C., et al. (2011). Effects of antipsychotics and amphetamine on social behaviors in spontaneously hypertensive rats. Behav. Brain Res. 225, 15-22. doi: 10.1016/j.bbr.2011.06.026.
    • (2011) Behav. Brain Res. , vol.225 , pp. 15-22
    • Calzavara, M.B.1    Levin, R.2    Medrano, W.A.3    Almeida, V.4    Sampaio, A.P.5    Barone, L.C.6
  • 18
    • 68149165786 scopus 로고    scopus 로고
    • Neuroleptic drugs revert the contextual fear conditioning deficit presented by spontaneously hypertensive rats: a potential animal model of emotional context processing in schizophrenia?
    • doi: 10.1093/schbul/sbn006
    • Calzavara, M. B., Medrano, W. A., Levin, R., Kameda, S. R., Andersen, M. L., Tufik, S., et al. (2009). Neuroleptic drugs revert the contextual fear conditioning deficit presented by spontaneously hypertensive rats: a potential animal model of emotional context processing in schizophrenia? Schizophr. Bull. 35, 748-759. doi: 10.1093/schbul/sbn006.
    • (2009) Schizophr. Bull. , vol.35 , pp. 748-759
    • Calzavara, M.B.1    Medrano, W.A.2    Levin, R.3    Kameda, S.R.4    Andersen, M.L.5    Tufik, S.6
  • 19
    • 84868122317 scopus 로고    scopus 로고
    • Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders
    • doi: 10.1098/rstb.2011.0389
    • Campos, A. C., Moreira, F. A., Gomes, F. V., Del Bel, E. A., and Guimaraes, F. S. (2012). Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. Philos. Trans. R. Soc. Lond. B Biol. Sci. 367, 3364-3378. doi: 10.1098/rstb.2011.0389.
    • (2012) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.367 , pp. 3364-3378
    • Campos, A.C.1    Moreira, F.A.2    Gomes, F.V.3    Del Bel, E.A.4    Guimaraes, F.S.5
  • 20
    • 78650597507 scopus 로고    scopus 로고
    • Therapeutical use of the cannabinoids in psychiatry
    • doi: 10.1590/S1516-44462010000500009
    • Crippa, J. A. S., Zuardi, A. W., and Hallak, J. E. C. (2010). Therapeutical use of the cannabinoids in psychiatry. Rev. Bras. Psiquiatr. 32, 556-566. doi: 10.1590/S1516-44462010000500009.
    • (2010) Rev. Bras. Psiquiatr. , vol.32 , pp. 556-566
    • Crippa, J.A.S.1    Zuardi, A.W.2    Hallak, J.E.C.3
  • 21
    • 50849144063 scopus 로고    scopus 로고
    • On the influence of baseline startle reactivity on the indexation of prepulse inhibition
    • doi: 10.1037/0735-7044.122.4.885
    • Csomor, P. A., Yee, B. K., Vollenweider, F. X., Feldon, J., Nicolet, T., and Quednow, B. B. (2008). On the influence of baseline startle reactivity on the indexation of prepulse inhibition. Behav. Neurosci. 122, 885-900. doi: 10.1037/0735-7044.122.4.885.
    • (2008) Behav. Neurosci. , vol.122 , pp. 885-900
    • Csomor, P.A.1    Yee, B.K.2    Vollenweider, F.X.3    Feldon, J.4    Nicolet, T.5    Quednow, B.B.6
  • 22
    • 79958818048 scopus 로고    scopus 로고
    • Paranoid schizophrenia is characterized by increased CB1 receptor binding in the dorsolateral prefrontal cortex
    • doi: 10.1038/npp.2011.43
    • Dalton, V. S., Long, L. E., Weickert, C. S., and Zavitsanou, K. (2011). Paranoid schizophrenia is characterized by increased CB1 receptor binding in the dorsolateral prefrontal cortex. Neuropsychopharmacology 36, 1620-1630. doi: 10.1038/npp.2011.43.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 1620-1630
    • Dalton, V.S.1    Long, L.E.2    Weickert, C.S.3    Zavitsanou, K.4
  • 23
    • 0035961131 scopus 로고    scopus 로고
    • Studies on [3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use
    • doi: 10.1016/S0306-4522(00)00552-2
    • Dean, B., Sundram, S., Bradbury, R., Scarr, E., and Copolov, D. (2001). Studies on [3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use. Neuroscience 103, 9-15. doi: 10.1016/S0306-4522(00)00552-2.
    • (2001) Neuroscience , vol.103 , pp. 9-15
    • Dean, B.1    Sundram, S.2    Bradbury, R.3    Scarr, E.4    Copolov, D.5
  • 25
    • 84873330323 scopus 로고    scopus 로고
    • Sensory gating, cannabinoids and schizophrenia
    • doi: 10.1016/j.neuropharm.2012.10.011
    • Dissanayake, D. W., Mason, R., and Marsden, C. A. (2013). Sensory gating, cannabinoids and schizophrenia. Neuropharmacology 67, 66-77. doi: 10.1016/j.neuropharm.2012.10.011.
    • (2013) Neuropharmacology , vol.67 , pp. 66-77
    • Dissanayake, D.W.1    Mason, R.2    Marsden, C.A.3
  • 26
    • 70349265973 scopus 로고    scopus 로고
    • Cannabis and psychosis/schizophrenia: human studies
    • doi: 10.1007/s00406-009-0024-2
    • D'Souza, D. C., Sewell, R. A., and Ranganathan, M. (2009). Cannabis and psychosis/schizophrenia: human studies. Eur. Arch. Psychiatry Clin. Neurosci. 259, 413-431. doi: 10.1007/s00406-009-0024-2.
    • (2009) Eur. Arch. Psychiatry Clin. Neurosci. , vol.259 , pp. 413-431
    • D'Souza, D.C.1    Sewell, R.A.2    Ranganathan, M.3
  • 27
    • 0037381574 scopus 로고    scopus 로고
    • A longitudinal study of short-and long-term activity levels in male and female spontaneously hypertensive, Wistar-Kyoto, and Sprague-Dawley rats
    • doi: 10.1037/0735-7044.117.2.271
    • Ferguson, S. A., and Cada, A. M. (2003). A longitudinal study of short-and long-term activity levels in male and female spontaneously hypertensive, Wistar-Kyoto, and Sprague-Dawley rats. Behav. Neurosci. 117, 271-282. doi: 10.1037/0735-7044.117.2.271.
    • (2003) Behav. Neurosci. , vol.117 , pp. 271-282
    • Ferguson, S.A.1    Cada, A.M.2
  • 28
    • 1542300279 scopus 로고    scopus 로고
    • Spatial learning/memory and social and nonsocial behaviors in the spontaneously hypertensive, Wistar-Kyoto and Sprague-Dawley rat strains
    • doi: 10.1016/j.pbb.2003.12.014
    • Ferguson, S. A., and Cada, A. M. (2004). Spatial learning/memory and social and nonsocial behaviors in the spontaneously hypertensive, Wistar-Kyoto and Sprague-Dawley rat strains. Pharmacol. Biochem. Behav. 77, 583-594. doi: 10.1016/j.pbb.2003.12.014.
    • (2004) Pharmacol. Biochem. Behav. , vol.77 , pp. 583-594
    • Ferguson, S.A.1    Cada, A.M.2
  • 29
    • 4544272564 scopus 로고    scopus 로고
    • Sensorimotor gating in mice is disrupted after AM404, an anandamide reuptake and degradation inhibitor
    • doi: 10.1007/s00213-004-1851-5
    • Fernandez-Espejo, E., and Galan-Rodriguez, B. (2004). Sensorimotor gating in mice is disrupted after AM404, an anandamide reuptake and degradation inhibitor. Psychopharmacology (Berl.) 175, 220-224. doi: 10.1007/s00213-004-1851-5.
    • (2004) Psychopharmacology (Berl.) , vol.175 , pp. 220-224
    • Fernandez-Espejo, E.1    Galan-Rodriguez, B.2
  • 30
    • 33847128328 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptor antagonism markedly increases dopamine receptor-mediated stereotypies
    • doi: 10.1016/j.ejphar.2007.01.009
    • Ferrer, B., Gorriti, M. A., Palomino, A., Gornemann, I., De Diego, Y., Bermudez-Silva, F. J., et al. (2007). Cannabinoid CB1 receptor antagonism markedly increases dopamine receptor-mediated stereotypies. Eur. J. Pharmacol 559, 180-183. doi: 10.1016/j.ejphar.2007.01.009.
    • (2007) Eur. J. Pharmacol , vol.559 , pp. 180-183
    • Ferrer, B.1    Gorriti, M.A.2    Palomino, A.3    Gornemann, I.4    De Diego, Y.5    Bermudez-Silva, F.J.6
  • 31
    • 84861993153 scopus 로고    scopus 로고
    • The endocannabinoid and endovanilloid systems interact in the rat prelimbic medial prefrontal cortex to control anxiety-like behavior
    • doi: 10.1016/j.neuropharm.2012.03.007
    • Fogaca, M. V., Aguiar, D. C., Moreira, F. A., and Guimaraes, F. S. (2012). The endocannabinoid and endovanilloid systems interact in the rat prelimbic medial prefrontal cortex to control anxiety-like behavior. Neuropharmacology 63, 202-210. doi: 10.1016/j.neuropharm.2012.03.007.
    • (2012) Neuropharmacology , vol.63 , pp. 202-210
    • Fogaca, M.V.1    Aguiar, D.C.2    Moreira, F.A.3    Guimaraes, F.S.4
  • 32
    • 84875494005 scopus 로고    scopus 로고
    • Neurophysiological effects of cannabinoids: implications for psychosis research
    • doi: 10.2174/138161212802884582
    • Gallinat, J., Rentzsch, J., and Roser, P. (2012). Neurophysiological effects of cannabinoids: implications for psychosis research. Curr. Pharm. Des. 18, 4938-4949. doi: 10.2174/138161212802884582.
    • (2012) Curr. Pharm. Des. , vol.18 , pp. 4938-4949
    • Gallinat, J.1    Rentzsch, J.2    Roser, P.3
  • 33
    • 8444242207 scopus 로고    scopus 로고
    • Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptoms
    • doi: 10.1038/sj.npp.1300558
    • Giuffrida, A., Leweke, F. M., Gerth, C. W., Schreiber, D., Koethe, D., Faulhaber, J., et al. (2004). Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptoms. Neuropsychopharmacology 29, 2108-2114. doi: 10.1038/sj.npp.1300558.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 2108-2114
    • Giuffrida, A.1    Leweke, F.M.2    Gerth, C.W.3    Schreiber, D.4    Koethe, D.5    Faulhaber, J.6
  • 34
    • 0034680851 scopus 로고    scopus 로고
    • Elevated circulating levels of anandamide after administration of the transport inhibitor, AM404
    • doi: 10.1016/S0014-2999(00)00786-X
    • Giuffrida, A., Rodriguez De Fonseca, F., Nava, F., Loubet-Lescoulie, P., and Piomelli, D. (2000). Elevated circulating levels of anandamide after administration of the transport inhibitor, AM404. Eur. J. Pharmacol. 408, 161-168. doi: 10.1016/S0014-2999(00)00786-X.
    • (2000) Eur. J. Pharmacol. , vol.408 , pp. 161-168
    • Giuffrida, A.1    Rodriguez De Fonseca, F.2    Nava, F.3    Loubet-Lescoulie, P.4    Piomelli, D.5
  • 35
    • 29144513466 scopus 로고    scopus 로고
    • Psychological effects of (S)-ketamine and N,N-dimethyltryptamine (DMT): a double-blind, cross-over study in healthy volunteers
    • doi: 10.1055/s-2005-916185
    • Gouzoulis-Mayfrank, E., Heekeren, K., Neukirch, A., Stoll, M., Stock, C., Obradovic, M., et al. (2005). Psychological effects of (S)-ketamine and N,N-dimethyltryptamine (DMT): a double-blind, cross-over study in healthy volunteers. Pharmacopsychiatry 38, 301-311. doi: 10.1055/s-2005-916185.
    • (2005) Pharmacopsychiatry , vol.38 , pp. 301-311
    • Gouzoulis-Mayfrank, E.1    Heekeren, K.2    Neukirch, A.3    Stoll, M.4    Stock, C.5    Obradovic, M.6
  • 36
    • 0027087246 scopus 로고
    • Startle gating deficits occur across prepulse intensities in schizophrenic patients
    • doi: 10.1016/0006-3223(92)90183-Z
    • Grillon, C., Ameli, R., Charney, D. S., Krystal, J., and Braff, D. (1992). Startle gating deficits occur across prepulse intensities in schizophrenic patients. Biol. Psychiatry 32, 939-943. doi: 10.1016/0006-3223(92)90183-Z.
    • (1992) Biol. Psychiatry , vol.32 , pp. 939-943
    • Grillon, C.1    Ameli, R.2    Charney, D.S.3    Krystal, J.4    Braff, D.5
  • 37
    • 0842347092 scopus 로고
    • A comparative study on some chemical and biological characteristics of various samples of cannabis resin
    • Grlie, L. (1976). A comparative study on some chemical and biological characteristics of various samples of cannabis resin. Bull. Narc. 14, 37-46.
    • (1976) Bull. Narc. , vol.14 , pp. 37-46
    • Grlie, L.1
  • 38
    • 79952748303 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptor antagonism prevents neurochemical and behavioural deficits induced by chronic phencyclidine
    • doi: 10.1017/S1461145710000209
    • Guidali, C., Vigano, D., Petrosino, S., Zamberletti, E., Realini, N., Binelli, G., et al. (2011). Cannabinoid CB1 receptor antagonism prevents neurochemical and behavioural deficits induced by chronic phencyclidine. Int. J. Neuropsychopharmacol. 14, 17-28. doi: 10.1017/S1461145710000209.
    • (2011) Int. J. Neuropsychopharmacol. , vol.14 , pp. 17-28
    • Guidali, C.1    Vigano, D.2    Petrosino, S.3    Zamberletti, E.4    Realini, N.5    Binelli, G.6
  • 39
    • 2442641276 scopus 로고    scopus 로고
    • Cannabidiol increases Fos expression in the nucleus accumbens but not in the dorsal striatum
    • doi: 10.1016/j.lfs.2004.01.015
    • Guimaraes, V. M., Zuardi, A. W., Del Bel, E. A., and Guimaraes, F. S. (2004). Cannabidiol increases Fos expression in the nucleus accumbens but not in the dorsal striatum. Life Sci. 75, 633-638. doi: 10.1016/j.lfs.2004.01.015.
    • (2004) Life Sci. , vol.75 , pp. 633-638
    • Guimaraes, V.M.1    Zuardi, A.W.2    Del Bel, E.A.3    Guimaraes, F.S.4
  • 40
    • 79955964765 scopus 로고    scopus 로고
    • Effect of cannabidiol in a MK-801-rodent model of aspects of schizophrenia
    • doi: 10.1016/j.bbr.2011.03.053
    • Gururajan, A., Taylor, D. A., and Malone, D. T. (2011). Effect of cannabidiol in a MK-801-rodent model of aspects of schizophrenia. Behav. Brain Res. 222, 299-308. doi: 10.1016/j.bbr.2011.03.053.
    • (2011) Behav. Brain Res. , vol.222 , pp. 299-308
    • Gururajan, A.1    Taylor, D.A.2    Malone, D.T.3
  • 41
    • 4544383665 scopus 로고    scopus 로고
    • Enhancement of anxiety-like responsiveness to the cannabinoid CB1 receptor agonist HU-210 following chronic stress
    • doi: 10.1016/j.ejphar.2004.06.069
    • Hill, M. N., and Gorzalka, B. B. (2004). Enhancement of anxiety-like responsiveness to the cannabinoid CB1 receptor agonist HU-210 following chronic stress. Eur. J. Pharmacol. 499, 291-295. doi: 10.1016/j.ejphar.2004.06.069.
    • (2004) Eur. J. Pharmacol. , vol.499 , pp. 291-295
    • Hill, M.N.1    Gorzalka, B.B.2
  • 42
    • 0026720883 scopus 로고
    • Genetic divergence between the Wistar-Kyoto rat and the spontaneously hypertensive rat
    • doi: 10.1161/01.HYP.19.5.425
    • Johnson, M. L., Ely, D. L., and Turner, M. E. (1992). Genetic divergence between the Wistar-Kyoto rat and the spontaneously hypertensive rat. Hypertension 19, 425-427. doi: 10.1161/01.HYP.19.5.425.
    • (1992) Hypertension , vol.19 , pp. 425-427
    • Johnson, M.L.1    Ely, D.L.2    Turner, M.E.3
  • 43
    • 33745029325 scopus 로고    scopus 로고
    • Chronic cannabis use is associated with attention-modulated reduction in prepulse inhibition of the startle reflex in healthy humans
    • doi: 10.1177/0269881105057516
    • Kedzior, K. K., and Martin-Iverson, M. T. (2006). Chronic cannabis use is associated with attention-modulated reduction in prepulse inhibition of the startle reflex in healthy humans. J. Psychopharmacol. 20, 471-484. doi: 10.1177/0269881105057516.
    • (2006) J. Psychopharmacol. , vol.20 , pp. 471-484
    • Kedzior, K.K.1    Martin-Iverson, M.T.2
  • 44
    • 78651292667 scopus 로고    scopus 로고
    • Effects of the cannabinoid-1 receptor antagonist rimonabant on psychiatric symptoms in overweight people with schizophrenia: a randomized, double-blind, pilot study
    • doi: 10.1097/JCP.0b013e318204825b
    • Kelly, D. L., Gorelick, D. A., Conley, R. R., Boggs, D. L., Linthicum, J., Liu, F., et al. (2011). Effects of the cannabinoid-1 receptor antagonist rimonabant on psychiatric symptoms in overweight people with schizophrenia: a randomized, double-blind, pilot study. J. Clin. Psychopharmacol. 31, 86-91. doi: 10.1097/JCP.0b013e318204825b.
    • (2011) J. Clin. Psychopharmacol. , vol.31 , pp. 86-91
    • Kelly, D.L.1    Gorelick, D.A.2    Conley, R.R.3    Boggs, D.L.4    Linthicum, J.5    Liu, F.6
  • 45
    • 32544432112 scopus 로고    scopus 로고
    • Algorithmically designed peptides ameliorate behavioral defects in animal model of ADHD by an allosteric mechanism
    • doi: 10.1016/j.jneumeth.2005.07.015
    • Kinkead, B., Selz, K. A., Owens, M. J., and Mandell, A. J. (2006). Algorithmically designed peptides ameliorate behavioral defects in animal model of ADHD by an allosteric mechanism. J. Neurosci. Methods 151, 68-81. doi: 10.1016/j.jneumeth.2005.07.015.
    • (2006) J. Neurosci. Methods , vol.151 , pp. 68-81
    • Kinkead, B.1    Selz, K.A.2    Owens, M.J.3    Mandell, A.J.4
  • 46
    • 70349652278 scopus 로고    scopus 로고
    • The endocannabinoid system as a target for modelling psychosis
    • doi: 10.1007/s00213-009-1591-7
    • Koethe, D., Hoyer, C., and Leweke, F. M. (2009). The endocannabinoid system as a target for modelling psychosis. Psychopharmacology (Berl.) 206, 551-561. doi: 10.1007/s00213-009-1591-7.
    • (2009) Psychopharmacology (Berl.) , vol.206 , pp. 551-561
    • Koethe, D.1    Hoyer, C.2    Leweke, F.M.3
  • 47
    • 0033190699 scopus 로고    scopus 로고
    • NMDA agonists and antagonists as probes of glutamatergic dysfunction and pharmacotherapies in neuropsychiatric disorders
    • Krystal, J. H., D'Souza, D. C., Petrakis, I. L., Belger, A., Berman, R. M., Charney, D. S., et al. (1999). NMDA agonists and antagonists as probes of glutamatergic dysfunction and pharmacotherapies in neuropsychiatric disorders. Harv. Rev. Psychiatry 7, 125-143.
    • (1999) Harv. Rev. Psychiatry , vol.7 , pp. 125-143
    • Krystal, J.H.1    D'Souza, D.C.2    Petrakis, I.L.3    Belger, A.4    Berman, R.M.5    Charney, D.S.6
  • 48
    • 84870803773 scopus 로고    scopus 로고
    • Antipsychotic profile of cannabidiol and rimonabant in an animal model of emotional context processing in schizophrenia
    • doi: 10.2174/138161212802884735
    • Levin, R., Almeida, V., Peres, F. F., Calzavara, M. B., Da Silva, N. D., Suiama, M. A., et al. (2012). Antipsychotic profile of cannabidiol and rimonabant in an animal model of emotional context processing in schizophrenia. Curr. Pharm. Des. 18, 4960-4965. doi: 10.2174/138161212802884735.
    • (2012) Curr. Pharm. Des. , vol.18 , pp. 4960-4965
    • Levin, R.1    Almeida, V.2    Peres, F.F.3    Calzavara, M.B.4    Da Silva, N.D.5    Suiama, M.A.6
  • 49
    • 79961127762 scopus 로고    scopus 로고
    • Spontaneously Hypertensive Rats (SHR) present deficits in prepulse inhibition of startle specifically reverted by clozapine
    • doi: 10.1016/j.pnpbp.2011.06.003
    • Levin, R., Calzavara, M. B., Santos, C. M., Medrano, W. A., Niigaki, S. T., and Abilio, V. C. (2011). Spontaneously Hypertensive Rats (SHR) present deficits in prepulse inhibition of startle specifically reverted by clozapine. Prog. Neuropsychopharmacol. Biol. Psychiatry 35, 1748-1752. doi: 10.1016/j.pnpbp.2011.06.003.
    • (2011) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.35 , pp. 1748-1752
    • Levin, R.1    Calzavara, M.B.2    Santos, C.M.3    Medrano, W.A.4    Niigaki, S.T.5    Abilio, V.C.6
  • 50
    • 10044238890 scopus 로고    scopus 로고
    • Cannabis-associated psychosis: current status of research
    • doi: 10.2165/00023210-200418130-00005
    • Leweke, F. M., Gerth, C. W., and Klosterkotter, J. (2004). Cannabis-associated psychosis: current status of research. CNS Drugs 18, 895-910. doi: 10.2165/00023210-200418130-00005.
    • (2004) CNS Drugs , vol.18 , pp. 895-910
    • Leweke, F.M.1    Gerth, C.W.2    Klosterkotter, J.3
  • 51
    • 0033519542 scopus 로고    scopus 로고
    • Elevated endogenous cannabinoids in schizophrenia
    • doi: 10.1097/00001756-199906030-00008
    • Leweke, F. M., Giuffrida, A., Wurster, U., Emrich, H. M., and Piomelli, D. (1999). Elevated endogenous cannabinoids in schizophrenia. Neuroreport 10, 1665-1669. doi: 10.1097/00001756-199906030-00008.
    • (1999) Neuroreport , vol.10 , pp. 1665-1669
    • Leweke, F.M.1    Giuffrida, A.2    Wurster, U.3    Emrich, H.M.4    Piomelli, D.5
  • 53
    • 84858391237 scopus 로고    scopus 로고
    • Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia
    • doi: 10.1038/tp.2012.15
    • Leweke, F. M., Piomelli, D., Pahlisch, F., Muhl, D., Gerth, C. W., Hoyer, C., et al. (2012). Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. Transl. Psychiatry 2, e94. doi: 10.1038/tp.2012.15.
    • (2012) Transl. Psychiatry , vol.2
    • Leweke, F.M.1    Piomelli, D.2    Pahlisch, F.3    Muhl, D.4    Gerth, C.W.5    Hoyer, C.6
  • 54
    • 0034080911 scopus 로고    scopus 로고
    • Different effects of nabilone and cannabidiol on binocular depth inversion in Man
    • doi: 10.1016/S0091-3057(00)00201-X
    • Leweke, F. M., Schneider, U., Radwan, M., Schmidt, E., and Emrich, H. M. (2000). Different effects of nabilone and cannabidiol on binocular depth inversion in Man. Pharmacol. Biochem. Behav. 66, 175-181. doi: 10.1016/S0091-3057(00)00201-X.
    • (2000) Pharmacol. Biochem. Behav. , vol.66 , pp. 175-181
    • Leweke, F.M.1    Schneider, U.2    Radwan, M.3    Schmidt, E.4    Emrich, H.M.5
  • 55
    • 84859258164 scopus 로고    scopus 로고
    • Distinct neurobehavioural effects of cannabidiol in transmembrane domain neuregulin 1 mutant mice
    • doi: 10.1371/journal.pone.0034129
    • Long, L. E., Chesworth, R., Huang, X. F., Wong, A., Spiro, A., Mcgregor, I. S., et al. (2012). Distinct neurobehavioural effects of cannabidiol in transmembrane domain neuregulin 1 mutant mice. PLoS ONE 7:e34129. doi: 10.1371/journal.pone.0034129.
    • (2012) PLoS ONE , vol.7
    • Long, L.E.1    Chesworth, R.2    Huang, X.F.3    Wong, A.4    Spiro, A.5    Mcgregor, I.S.6
  • 56
    • 33645029075 scopus 로고    scopus 로고
    • Cannabidiol reverses MK-801-induced disruption of prepulse inhibition in mice
    • doi: 10.1038/sj.npp.1300838
    • Long, L. E., Malone, D. T., and Taylor, D. A. (2006). Cannabidiol reverses MK-801-induced disruption of prepulse inhibition in mice. Neuropsychopharmacology 31, 795-803. doi: 10.1038/sj.npp.1300838.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 795-803
    • Long, L.E.1    Malone, D.T.2    Taylor, D.A.3
  • 57
    • 67649274432 scopus 로고    scopus 로고
    • Cannabidiol reverses the reduction in social interaction produced by low dose Δ 9-tetrahydrocannabinol in rats
    • doi: 10.1016/j.pbb.2009.04.010
    • Malone, D. T., Jongejan, D., and Taylor, D. A. (2009). Cannabidiol reverses the reduction in social interaction produced by low dose Δ 9-tetrahydrocannabinol in rats. Pharmacol. Biochem. Behav. 93, 91-96. doi: 10.1016/j.pbb.2009.04.010.
    • (2009) Pharmacol. Biochem. Behav. , vol.93 , pp. 91-96
    • Malone, D.T.1    Jongejan, D.2    Taylor, D.A.3
  • 58
    • 1942455357 scopus 로고    scopus 로고
    • The effect of SR 141716 and apomorphine on sensorimotor gating in Swiss mice
    • doi: 10.1016/j.pbb.2004.02.010
    • Malone, D. T., Long, L. E., and Taylor, D. A. (2004). The effect of SR 141716 and apomorphine on sensorimotor gating in Swiss mice. Pharmacol. Biochem. Behav. 77, 839-845. doi: 10.1016/j.pbb.2004.02.010.
    • (2004) Pharmacol. Biochem. Behav. , vol.77 , pp. 839-845
    • Malone, D.T.1    Long, L.E.2    Taylor, D.A.3
  • 59
    • 27944484447 scopus 로고    scopus 로고
    • The effect of Δ 9-tetrahydrocannabinol on sensorimotor gating in socially isolated rats
    • doi: 10.1016/j.bbr.2005.07.009
    • Malone, D. T., and Taylor, D. A. (2006). The effect of Δ 9-tetrahydrocannabinol on sensorimotor gating in socially isolated rats. Behav. Brain Res. 166, 101-109. doi: 10.1016/j.bbr.2005.07.009.
    • (2006) Behav. Brain Res. , vol.166 , pp. 101-109
    • Malone, D.T.1    Taylor, D.A.2
  • 61
    • 79957623003 scopus 로고    scopus 로고
    • Failure to sustain prepulse inhibition in adolescent marijuana users
    • doi: 10.1016/j.drugalcdep.2010.11.020
    • Mathias, C. W., Blumenthal, T. D., Dawes, M. A., Liguori, A., Richard, D. M., Bray, B., et al. (2011). Failure to sustain prepulse inhibition in adolescent marijuana users. Drug Alcohol Depend. 116, 110-116. doi: 10.1016/j.drugalcdep.2010.11.020.
    • (2011) Drug Alcohol Depend. , vol.116 , pp. 110-116
    • Mathias, C.W.1    Blumenthal, T.D.2    Dawes, M.A.3    Liguori, A.4    Richard, D.M.5    Bray, B.6
  • 62
    • 2942538034 scopus 로고    scopus 로고
    • Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder
    • doi: 10.1176/appi.ajp.161.6.975
    • Meltzer, H. Y., Arvanitis, L., Bauer, D., and Rein, W. (2004). Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder. Am. J. Psychiatry 161, 975-984. doi: 10.1176/appi.ajp.161.6.975.
    • (2004) Am. J. Psychiatry , vol.161 , pp. 975-984
    • Meltzer, H.Y.1    Arvanitis, L.2    Bauer, D.3    Rein, W.4
  • 63
    • 84861303384 scopus 로고    scopus 로고
    • Bimodal control of fear-coping strategies by CB1 cannabinoid receptors
    • doi: 10.1523/JNEUROSCI.1054-12.2012
    • Metna-Laurent, M., Soria-Gomez, E., Verrier, D., Conforzi, M., Jego, P., Lafenetre, P., et al. (2012). Bimodal control of fear-coping strategies by CB1 cannabinoid receptors. J. Neurosci. 32, 7109-7118. doi: 10.1523/JNEUROSCI.1054-12.2012.
    • (2012) J. Neurosci. , vol.32 , pp. 7109-7118
    • Metna-Laurent, M.1    Soria-Gomez, E.2    Verrier, D.3    Conforzi, M.4    Jego, P.5    Lafenetre, P.6
  • 64
    • 17444393586 scopus 로고    scopus 로고
    • Cannabidiol inhibits the hyperlocomotion induced by psychotomimetic drugs in mice
    • doi: 10.1016/j.ejphar.2005.02.040
    • Moreira, F. A., and Guimaraes, F. S. (2005). Cannabidiol inhibits the hyperlocomotion induced by psychotomimetic drugs in mice. Eur. J. Pharmacol. 512, 199-205. doi: 10.1016/j.ejphar.2005.02.040.
    • (2005) Eur. J. Pharmacol. , vol.512 , pp. 199-205
    • Moreira, F.A.1    Guimaraes, F.S.2
  • 65
    • 43949084075 scopus 로고    scopus 로고
    • The endocannabinoid system: emotion, learning and addiction
    • doi: 10.1111/j.1369-1600.2008.00104.x
    • Moreira, F. A., and Lutz, B. (2008). The endocannabinoid system: emotion, learning and addiction. Addict. Biol. 13, 196-212. doi: 10.1111/j.1369-1600.2008.00104.x.
    • (2008) Addict. Biol. , vol.13 , pp. 196-212
    • Moreira, F.A.1    Lutz, B.2
  • 66
    • 33745623410 scopus 로고    scopus 로고
    • Increased cannabinoid receptor density in the posterior cingulate cortex in schizophrenia
    • doi: 10.1007/s00221-006-0503-x
    • Newell, K. A., Deng, C., and Huang, X. F. (2006). Increased cannabinoid receptor density in the posterior cingulate cortex in schizophrenia. Exp. Brain Res. 172, 556-560. doi: 10.1007/s00221-006-0503-x.
    • (2006) Exp. Brain Res. , vol.172 , pp. 556-560
    • Newell, K.A.1    Deng, C.2    Huang, X.F.3
  • 67
    • 0011910306 scopus 로고
    • Development of a strain of spontaneously hypertensive rats
    • doi: 10.1253/jcj.27.282
    • Okamoto, K., and Aoki, K. (1963). Development of a strain of spontaneously hypertensive rats. Jpn. Circ. J. 27, 282-293. doi: 10.1253/jcj.27.282.
    • (1963) Jpn. Circ. J. , vol.27 , pp. 282-293
    • Okamoto, K.1    Aoki, K.2
  • 68
    • 0033942808 scopus 로고    scopus 로고
    • Prepulse startle deficit in the Brown Norway rat: a potential genetic model
    • doi: 10.1037/0735-7044.114.2.374
    • Palmer, A. A., Dulawa, S. C., Mottiwala, A. A., Conti, L. H., Geyer, M. A., and Printz, M. P. (2000). Prepulse startle deficit in the Brown Norway rat: a potential genetic model. Behav. Neurosci. 114, 374-388. doi: 10.1037/0735-7044.114.2.374.
    • (2000) Behav. Neurosci. , vol.114 , pp. 374-388
    • Palmer, A.A.1    Dulawa, S.C.2    Mottiwala, A.A.3    Conti, L.H.4    Geyer, M.A.5    Printz, M.P.6
  • 69
    • 33644755672 scopus 로고    scopus 로고
    • WIN 55212-2 impairs contextual fear conditioning through the activation of CB1 cannabinoid receptors
    • doi: 10.1016/j.neulet.2005.12.026
    • Pamplona, F. A., and Takahashi, R. N. (2006). WIN 55212-2 impairs contextual fear conditioning through the activation of CB1 cannabinoid receptors. Neurosci. Lett. 397, 88-92. doi: 10.1016/j.neulet.2005.12.026.
    • (2006) Neurosci. Lett. , vol.397 , pp. 88-92
    • Pamplona, F.A.1    Takahashi, R.N.2
  • 70
    • 0026844301 scopus 로고
    • Learning behavior, escape behavior, and depression in an ulcer susceptible rat strain
    • doi: 10.1007/BF02698502
    • Pare, W. P. (1992). Learning behavior, escape behavior, and depression in an ulcer susceptible rat strain. Integr. Physiol. Behav. Sci. 27, 130-141. doi: 10.1007/BF02698502.
    • (1992) Integr. Physiol. Behav. Sci. , vol.27 , pp. 130-141
    • Pare, W.P.1
  • 71
    • 0028224173 scopus 로고
    • Open field, learned helplessness, conditioned defensive burying, and forced-swim tests in WKY rats
    • doi: 10.1016/0031-9384(94)90097-3
    • Pare, W. P. (1994). Open field, learned helplessness, conditioned defensive burying, and forced-swim tests in WKY rats. Physiol. Behav. 55, 433-439. doi: 10.1016/0031-9384(94)90097-3.
    • (1994) Physiol. Behav. , vol.55 , pp. 433-439
    • Pare, W.P.1
  • 72
    • 0026599635 scopus 로고
    • Influence of cannabis abuse on schizophrenic psychopathology
    • doi: 10.1111/j.1600-0447.1992.tb01456.x
    • Peralta, V., and Cuesta, M. J. (1992). Influence of cannabis abuse on schizophrenic psychopathology. Acta Psychiatr. Scand. 85, 127-130. doi: 10.1111/j.1600-0447.1992.tb01456.x.
    • (1992) Acta Psychiatr. Scand. , vol.85 , pp. 127-130
    • Peralta, V.1    Cuesta, M.J.2
  • 73
    • 38349158960 scopus 로고    scopus 로고
    • 9-tetrahydrocannabivarin
    • doi: 10.1038/sj.bjp.0707442
    • 9-tetrahydrocannabivarin. Br. J. Pharmacol. 153, 199-215. doi: 10.1038/sj.bjp.0707442.
    • (2008) Br. J. Pharmacol. , vol.153 , pp. 199-215
    • Pertwee, R.G.1
  • 74
    • 84875941411 scopus 로고    scopus 로고
    • The cannabinoid CB1 receptor biphasically modulates motor activity and regulates dopamine and glutamate release region dependently
    • doi: 10.1017/S1461145712000156
    • Polissidis, A., Galanopoulos, A., Naxakis, G., Papahatjis, D., Papadopoulou-Daifoti, Z., and Antoniou, K. (2013). The cannabinoid CB1 receptor biphasically modulates motor activity and regulates dopamine and glutamate release region dependently. Int. J. Neuropsychopharmacol. 16, 393-403. doi: 10.1017/S1461145712000156.
    • (2013) Int. J. Neuropsychopharmacol. , vol.16 , pp. 393-403
    • Polissidis, A.1    Galanopoulos, A.2    Naxakis, G.3    Papahatjis, D.4    Papadopoulou-Daifoti, Z.5    Antoniou, K.6
  • 75
    • 53249088295 scopus 로고    scopus 로고
    • Impaired sensorimotor gating of the acoustic startle response in the prodrome of schizophrenia
    • doi: 10.1016/j.biopsych.2008.04.019
    • Quednow, B. B., Frommann, I., Berning, J., Kuhn, K. U., Maier, W., and Wagner, M. (2008). Impaired sensorimotor gating of the acoustic startle response in the prodrome of schizophrenia. Biol. Psychiatry 64, 766-773. doi: 10.1016/j.biopsych.2008.04.019.
    • (2008) Biol. Psychiatry , vol.64 , pp. 766-773
    • Quednow, B.B.1    Frommann, I.2    Berning, J.3    Kuhn, K.U.4    Maier, W.5    Wagner, M.6
  • 76
    • 11144353964 scopus 로고    scopus 로고
    • Prepulse inhibition and habituation of acoustic startle response in male MDMA ('ecstasy') users, cannabis users, and healthy controls
    • doi: 10.1038/sj.npp.1300396
    • Quednow, B. B., Kuhn, K. U., Hoenig, K., Maier, W., and Wagner, M. (2004). Prepulse inhibition and habituation of acoustic startle response in male MDMA ('ecstasy') users, cannabis users, and healthy controls. Neuropsychopharmacology 29, 982-990. doi: 10.1038/sj.npp.1300396.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 982-990
    • Quednow, B.B.1    Kuhn, K.U.2    Hoenig, K.3    Maier, W.4    Wagner, M.5
  • 77
    • 33644611674 scopus 로고    scopus 로고
    • Sensorimotor gating and habituation of the startle response in schizophrenic patients randomly treated with amisulpride or olanzapine
    • doi: 10.1016/j.biopsych.2005.07.012
    • Quednow, B. B., Wagner, M., Westheide, J., Beckmann, K., Bliesener, N., Maier, W., et al. (2006). Sensorimotor gating and habituation of the startle response in schizophrenic patients randomly treated with amisulpride or olanzapine. Biol. Psychiatry 59, 536-545. doi: 10.1016/j.biopsych.2005.07.012.
    • (2006) Biol. Psychiatry , vol.59 , pp. 536-545
    • Quednow, B.B.1    Wagner, M.2    Westheide, J.3    Beckmann, K.4    Bliesener, N.5    Maier, W.6
  • 78
    • 0028129936 scopus 로고
    • SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
    • doi: 10.1016/0014-5793(94)00773-X
    • Rinaldi-Carmona, M., Barth, F., Heaulme, M., Shire, D., Calandra, B., Congy, C., et al. (1994). SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett. 350, 240-244. doi: 10.1016/0014-5793(94)00773-X.
    • (1994) FEBS Lett. , vol.350 , pp. 240-244
    • Rinaldi-Carmona, M.1    Barth, F.2    Heaulme, M.3    Shire, D.4    Calandra, B.5    Congy, C.6
  • 79
    • 0026565729 scopus 로고
    • Neuroleptics increase c-fos expression in the forebrain: contrasting effects of haloperidol and clozapine
    • doi: 10.1016/0306-4522(92)90054-6
    • Robertson, G. S., and Fibiger, H. C. (1992). Neuroleptics increase c-fos expression in the forebrain: contrasting effects of haloperidol and clozapine. Neuroscience 46, 315-328. doi: 10.1016/0306-4522(92)90054-6.
    • (1992) Neuroscience , vol.46 , pp. 315-328
    • Robertson, G.S.1    Fibiger, H.C.2
  • 80
    • 84873344483 scopus 로고    scopus 로고
    • Antipsychotic-like effects of cannabidiol and rimonabant: systematic review of animal and human studies
    • doi: 10.2174/138161212802884690
    • Roser, P., and Haussleiter, I. S. (2012). Antipsychotic-like effects of cannabidiol and rimonabant: systematic review of animal and human studies. Curr. Pharm. Des. 18, 5141-5155. doi: 10.2174/138161212802884690.
    • (2012) Curr. Pharm. Des. , vol.18 , pp. 5141-5155
    • Roser, P.1    Haussleiter, I.S.2
  • 81
    • 82955249251 scopus 로고    scopus 로고
    • Inhibition of cerebral type 1 cannabinoid receptors is associated with impaired auditory mismatch negativity generation in the ketamine model of schizophrenia
    • doi: 10.1007/s00213-011-2352-y
    • Roser, P., Haussleiter, I. S., Chong, H. J., Maier, C., Kawohl, W., Norra, C., et al. (2011). Inhibition of cerebral type 1 cannabinoid receptors is associated with impaired auditory mismatch negativity generation in the ketamine model of schizophrenia. Psychopharmacology (Berl.) 218, 611-620. doi: 10.1007/s00213-011-2352-y.
    • (2011) Psychopharmacology (Berl.) , vol.218 , pp. 611-620
    • Roser, P.1    Haussleiter, I.S.2    Chong, H.J.3    Maier, C.4    Kawohl, W.5    Norra, C.6
  • 82
    • 77950834228 scopus 로고    scopus 로고
    • Potential antipsychotic properties of central cannabinoid CB1 receptor antagonists
    • doi: 10.3109/15622970801908047
    • Roser, P., Vollenweider, F. X., and Kawohl, W. (2010). Potential antipsychotic properties of central cannabinoid CB1 receptor antagonists. World J. Biol. Psychiatry 11, 208-219. doi: 10.3109/15622970801908047.
    • (2010) World J. Biol. Psychiatry , vol.11 , pp. 208-219
    • Roser, P.1    Vollenweider, F.X.2    Kawohl, W.3
  • 83
    • 33947540328 scopus 로고    scopus 로고
    • Neurobiology of animal models of attention-deficit hyperactivity disorder
    • doi: 10.1016/j.jneumeth.2006.12.005
    • Russell, V. A. (2007). Neurobiology of animal models of attention-deficit hyperactivity disorder. J. Neurosci. Methods 161, 185-198. doi: 10.1016/j.jneumeth.2006.12.005.
    • (2007) J. Neurosci. Methods , vol.161 , pp. 185-198
    • Russell, V.A.1
  • 84
    • 27644440716 scopus 로고    scopus 로고
    • Agonistic properties of cannabidiol at 5-HT1a receptors
    • doi: 10.1007/s11064-005-6978-1
    • Russo, E. B., Burnett, A., Hall, B., and Parker, K. K. (2005). Agonistic properties of cannabidiol at 5-HT1a receptors. Neurochem. Res. 30, 1037-1043. doi: 10.1007/s11064-005-6978-1.
    • (2005) Neurochem. Res. , vol.30 , pp. 1037-1043
    • Russo, E.B.1    Burnett, A.2    Hall, B.3    Parker, K.K.4
  • 85
    • 0026498641 scopus 로고
    • The spontaneously hypertensive rat (SHR) as an animal model of childhood hyperactivity (ADHD): changed reactivity to reinforcers and to psychomotor stimulants
    • doi: 10.1016/0163-1047(92)90315-U
    • Sagvolden, T., Metzger, M. A., Schiorbeck, H. K., Rugland, A. L., Spinnangr, I., and Sagvolden, G. (1992). The spontaneously hypertensive rat (SHR) as an animal model of childhood hyperactivity (ADHD): changed reactivity to reinforcers and to psychomotor stimulants. Behav. Neural. Biol. 58, 103-112. doi: 10.1016/0163-1047(92)90315-U.
    • (1992) Behav. Neural. Biol. , vol.58 , pp. 103-112
    • Sagvolden, T.1    Metzger, M.A.2    Schiorbeck, H.K.3    Rugland, A.L.4    Spinnangr, I.5    Sagvolden, G.6
  • 86
    • 0031855726 scopus 로고    scopus 로고
    • Attention deficit/hyperactivity disorder-from brain dysfunctions to behaviour
    • doi: 10.1016/S0166-4328(97)00164-2
    • Sagvolden, T., and Sergeant, J. A. (1998). Attention deficit/hyperactivity disorder-from brain dysfunctions to behaviour. Behav. Brain Res. 94, 1-10. doi: 10.1016/S0166-4328(97)00164-2.
    • (1998) Behav. Brain Res. , vol.94 , pp. 1-10
    • Sagvolden, T.1    Sergeant, J.A.2
  • 87
    • 0031909405 scopus 로고    scopus 로고
    • A test of the predictive validity of animal models of schizophrenia based on phencyclidine and D-amphetamine
    • doi: 10.1016/S0893-133X(97)00161-9
    • Sams-Dodd, F. (1998). A test of the predictive validity of animal models of schizophrenia based on phencyclidine and D-amphetamine. Neuropsychopharmacology 18, 293-304. doi: 10.1016/S0893-133X(97)00161-9.
    • (1998) Neuropsychopharmacology , vol.18 , pp. 293-304
    • Sams-Dodd, F.1
  • 88
    • 0035499974 scopus 로고    scopus 로고
    • Modulation of transmitter release via presynaptic cannabinoid receptors
    • doi: 10.1016/S0165-6147(00)01805-8
    • Schlicker, E., and Kathmann, M. (2001). Modulation of transmitter release via presynaptic cannabinoid receptors. Trends Pharmacol. Sci. 22, 565-572. doi: 10.1016/S0165-6147(00)01805-8.
    • (2001) Trends Pharmacol. Sci. , vol.22 , pp. 565-572
    • Schlicker, E.1    Kathmann, M.2
  • 89
    • 0036180943 scopus 로고    scopus 로고
    • The cannabinoid agonist WIN 55,212-2 reduces sensorimotor gating and recognition memory in rats
    • doi: 10.1097/00008877-200202000-00003
    • Schneider, M., and Koch, M. (2002). The cannabinoid agonist WIN 55,212-2 reduces sensorimotor gating and recognition memory in rats. Behav. Pharmacol. 13, 29-37. doi: 10.1097/00008877-200202000-00003.
    • (2002) Behav. Pharmacol. , vol.13 , pp. 29-37
    • Schneider, M.1    Koch, M.2
  • 90
    • 67649265233 scopus 로고    scopus 로고
    • Synthetic Δ-9-tetrahydrocannabinol (dronabinol) can improve the symptoms of schizophrenia
    • doi: 10.1097/JCP.0b013e3181a6bc3b
    • Schwarcz, G., Karajgi, B., and Mccarthy, R. (2009). Synthetic Δ-9-tetrahydrocannabinol (dronabinol) can improve the symptoms of schizophrenia. J. Clin. Psychopharmacol. 29, 255-258. doi: 10.1097/JCP.0b013e3181a6bc3b.
    • (2009) J. Clin. Psychopharmacol. , vol.29 , pp. 255-258
    • Schwarcz, G.1    Karajgi, B.2    Mccarthy, R.3
  • 91
    • 77952882862 scopus 로고    scopus 로고
    • Inhibition of fatty-acid amide hydrolase and CB1 receptor antagonism differentially affect behavioural responses in normal and PCP-treated rats
    • doi: 10.1017/S146114570999023X
    • Seillier, A., Advani, T., Cassano, T., Hensler, J. G., and Giuffrida, A. (2010). Inhibition of fatty-acid amide hydrolase and CB1 receptor antagonism differentially affect behavioural responses in normal and PCP-treated rats. Int. J. Neuropsychopharmacol. 13, 373-386. doi: 10.1017/S146114570999023X.
    • (2010) Int. J. Neuropsychopharmacol. , vol.13 , pp. 373-386
    • Seillier, A.1    Advani, T.2    Cassano, T.3    Hensler, J.G.4    Giuffrida, A.5
  • 92
    • 79851503776 scopus 로고    scopus 로고
    • Behavioral, cognitive and psychophysiological effects of cannabinoids: relevance to psychosis and schizophrenia
    • doi: 10.1590/S1516-44462010000500005
    • Sewell, R. A., Skosnik, P. D., Garcia-Sosa, I., Ranganathan, M., and D'Souza, D. C. (2010). Behavioral, cognitive and psychophysiological effects of cannabinoids: relevance to psychosis and schizophrenia. Rev. Bras. Psiquiatr. 32(Suppl. 1), S15-S30. doi: 10.1590/S1516-44462010000500005.
    • (2010) Rev. Bras. Psiquiatr. , vol.32 , Issue.SUPPL. 1
    • Sewell, R.A.1    Skosnik, P.D.2    Garcia-Sosa, I.3    Ranganathan, M.4    D'Souza, D.C.5
  • 93
    • 71549147546 scopus 로고    scopus 로고
    • Cannabinoid self-administration attenuates PCP-induced schizophrenia-like symptoms in adult rats
    • doi: 10.1016/j.euroneuro.2009.09.004
    • Spano, M. S., Fadda, P., Frau, R., Fattore, L., and Fratta, W. (2010). Cannabinoid self-administration attenuates PCP-induced schizophrenia-like symptoms in adult rats. Eur. Neuropsychopharmacol. 20, 25-36. doi: 10.1016/j.euroneuro.2009.09.004.
    • (2010) Eur. Neuropsychopharmacol. , vol.20 , pp. 25-36
    • Spano, M.S.1    Fadda, P.2    Frau, R.3    Fattore, L.4    Fratta, W.5
  • 94
    • 84873720051 scopus 로고    scopus 로고
    • Chronic cannabinoid exposure reduces phencyclidine-induced schizophrenia-like positive symptoms in adult rats
    • doi: 10.1007/s00213-012-2839-1
    • Spano, M. S., Fattore, L., Cadeddu, F., Fratta, W., and Fadda, P. (2012). Chronic cannabinoid exposure reduces phencyclidine-induced schizophrenia-like positive symptoms in adult rats. Psychopharmacology (Berl.) 225, 531-542. doi: 10.1007/s00213-012-2839-1.
    • (2012) Psychopharmacology (Berl.) , vol.225 , pp. 531-542
    • Spano, M.S.1    Fattore, L.2    Cadeddu, F.3    Fratta, W.4    Fadda, P.5
  • 95
    • 0026681077 scopus 로고
    • Hypertensive strains and normotensive 'control' strains. How closely are they related?
    • doi: 10.1161/01.HYP.19.5.419
    • St Lezin, E., Simonet, L., Pravenec, M., and Kurtz, T. W. (1992). Hypertensive strains and normotensive 'control' strains. How closely are they related? Hypertension 19, 419-424. doi: 10.1161/01.HYP.19.5.419.
    • (1992) Hypertension , vol.19 , pp. 419-424
    • St Lezin, E.1    Simonet, L.2    Pravenec, M.3    Kurtz, T.W.4
  • 96
    • 0033938877 scopus 로고    scopus 로고
    • Animal models of deficient sensorimotor gating: what we know, what we think we know, and what we hope to know soon
    • doi: 10.1097/00008877-200006000-00002
    • Swerdlow, N. R., Braff, D. L., and Geyer, M. A. (2000). Animal models of deficient sensorimotor gating: what we know, what we think we know, and what we hope to know soon. Behav. Pharmacol. 11, 185-204. doi: 10.1097/00008877-200006000-00002.
    • (2000) Behav. Pharmacol. , vol.11 , pp. 185-204
    • Swerdlow, N.R.1    Braff, D.L.2    Geyer, M.A.3
  • 97
    • 0028371468 scopus 로고
    • Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients
    • doi: 10.1001/archpsyc.1994.03950020063007
    • Swerdlow, N. R., Braff, D. L., Taaid, N., and Geyer, M. A. (1994). Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients. Arch. Gen. Psychiatry 51, 139-154. doi: 10.1001/archpsyc.1994.03950020063007.
    • (1994) Arch. Gen. Psychiatry , vol.51 , pp. 139-154
    • Swerdlow, N.R.1    Braff, D.L.2    Taaid, N.3    Geyer, M.A.4
  • 98
    • 0034927844 scopus 로고    scopus 로고
    • Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges
    • doi: 10.1007/s002130100799
    • Swerdlow, N. R., Geyer, M. A., and Braff, D. L. (2001). Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges. Psychopharmacology (Berl.) 156, 194-215. doi: 10.1007/s002130100799.
    • (2001) Psychopharmacology (Berl.) , vol.156 , pp. 194-215
    • Swerdlow, N.R.1    Geyer, M.A.2    Braff, D.L.3
  • 99
    • 12844257483 scopus 로고    scopus 로고
    • Neurochemical analysis of rat strain differences in the startle gating-disruptive effects of dopamine agonists
    • doi: 10.1016/j.pbb.2004.11.002
    • Swerdlow, N. R., Kuczenski, R., Goins, J. C., Crain, S. K., Ma, L. T., Bongiovanni, M. J., et al. (2005). Neurochemical analysis of rat strain differences in the startle gating-disruptive effects of dopamine agonists. Pharmacol. Biochem. Behav. 80, 203-211. doi: 10.1016/j.pbb.2004.11.002.
    • (2005) Pharmacol. Biochem. Behav. , vol.80 , pp. 203-211
    • Swerdlow, N.R.1    Kuczenski, R.2    Goins, J.C.3    Crain, S.K.4    Ma, L.T.5    Bongiovanni, M.J.6
  • 100
    • 12444281775 scopus 로고    scopus 로고
    • New perspectives in the studies on endocannabinoid and cannabis: cannabinoid receptors and schizophrenia
    • doi: 10.1254/jphs.FMJ04003X4
    • Ujike, H., and Morita, Y. (2004). New perspectives in the studies on endocannabinoid and cannabis: cannabinoid receptors and schizophrenia. J. Pharmacol. Sci. 96, 376-381. doi: 10.1254/jphs.FMJ04003X4.
    • (2004) J. Pharmacol. Sci. , vol.96 , pp. 376-381
    • Ujike, H.1    Morita, Y.2
  • 101
    • 33646682434 scopus 로고    scopus 로고
    • Spontaneously hypertensive rats do not predict symptoms of attention-deficit hyperactivity disorder
    • doi: 10.1016/j.pbb.2006.02.018
    • van den Bergh, F. S., Bloemarts, E., Chan, J. S., Groenink, L., Olivier, B., and Oosting, R. S. (2006). Spontaneously hypertensive rats do not predict symptoms of attention-deficit hyperactivity disorder. Pharmacol. Biochem. Behav. 83, 380-390. doi: 10.1016/j.pbb.2006.02.018.
    • (2006) Pharmacol. Biochem. Behav. , vol.83 , pp. 380-390
    • Van den Bergh, F.S.1    Bloemarts, E.2    Chan, J.S.3    Groenink, L.4    Olivier, B.5    Oosting, R.S.6
  • 102
    • 4143069010 scopus 로고    scopus 로고
    • Prepulse inhibition of acoustic startle in spontaneously hypertensive rats
    • doi: 10.1016/j.bbr.2004.02.021
    • van den Buuse, M. (2004). Prepulse inhibition of acoustic startle in spontaneously hypertensive rats. Behav. Brain Res. 154, 331-337. doi: 10.1016/j.bbr.2004.02.021.
    • (2004) Behav. Brain Res. , vol.154 , pp. 331-337
    • van den Buuse, M.1
  • 103
    • 33746993534 scopus 로고    scopus 로고
    • A QTL on rat chromosome 7 modulates prepulse inhibition, a neuro-behavioral trait of ADHD, in a Lewis x SHR intercross
    • doi: 10.1186/1744-9081-2-21
    • Vendruscolo, L. F., Terenina-Rigaldie, E., Raba, F., Ramos, A., Takahashi, R. N., and Mormede, P. (2006). A QTL on rat chromosome 7 modulates prepulse inhibition, a neuro-behavioral trait of ADHD, in a Lewis x SHR intercross. Behav. Brain Funct. 2, 21. doi: 10.1186/1744-9081-2-21.
    • (2006) Behav. Brain Funct. , vol.2 , pp. 21
    • Vendruscolo, L.F.1    Terenina-Rigaldie, E.2    Raba, F.3    Ramos, A.4    Takahashi, R.N.5    Mormede, P.6
  • 104
    • 25444469638 scopus 로고    scopus 로고
    • Impact of substance use on the onset and course of early psychosis
    • doi: 10.1016/j.schres.2004.12.008
    • Verdoux, H., Tournier, M., and Cougnard, A. (2005). Impact of substance use on the onset and course of early psychosis. Schizophr. Res. 79, 69-75. doi: 10.1016/j.schres.2004.12.008.
    • (2005) Schizophr. Res. , vol.79 , pp. 69-75
    • Verdoux, H.1    Tournier, M.2    Cougnard, A.3
  • 105
    • 20444379218 scopus 로고    scopus 로고
    • Endocannabinoid system and stress and anxiety responses
    • doi: 10.1016/j.pbb.2005.01.029
    • Viveros, M. P., Marco, E. M., and File, S. E. (2005). Endocannabinoid system and stress and anxiety responses. Pharmacol. Biochem. Behav. 81, 331-342. doi: 10.1016/j.pbb.2005.01.029.
    • (2005) Pharmacol. Biochem. Behav. , vol.81 , pp. 331-342
    • Viveros, M.P.1    Marco, E.M.2    File, S.E.3
  • 106
    • 44249087350 scopus 로고    scopus 로고
    • Effects of acute systemic and intra-cerebral stimulation of cannabinoid receptors on sensorimotor gating, locomotion and spatial memory in rats
    • doi: 10.1007/s00213-008-1148-1
    • Wegener, N., Kuhnert, S., Thuns, A., Roese, R., and Koch, M. (2008). Effects of acute systemic and intra-cerebral stimulation of cannabinoid receptors on sensorimotor gating, locomotion and spatial memory in rats. Psychopharmacology (Berl.) 198, 375-385. doi: 10.1007/s00213-008-1148-1.
    • (2008) Psychopharmacology (Berl.) , vol.198 , pp. 375-385
    • Wegener, N.1    Kuhnert, S.2    Thuns, A.3    Roese, R.4    Koch, M.5
  • 107
    • 0007182459 scopus 로고    scopus 로고
    • Effective neuroleptic medication removes prepulse inhibition deficits in schizophrenia patients
    • doi: 10.1016/S0006-3223(99)00229-2
    • Weike, A. I., Bauer, U., and Hamm, A. O. (2000). Effective neuroleptic medication removes prepulse inhibition deficits in schizophrenia patients. Biol. Psychiatry 47, 61-70. doi: 10.1016/S0006-3223(99)00229-2.
    • (2000) Biol. Psychiatry , vol.47 , pp. 61-70
    • Weike, A.I.1    Bauer, U.2    Hamm, A.O.3
  • 108
    • 0033913927 scopus 로고    scopus 로고
    • Strain differences in the isolation-induced effects on prepulse inhibition of the acoustic startle response and on locomotor activity
    • doi: 10.1037/0735-7044.114.2.364
    • Weiss, I. C., Di Iorio, L., Feldon, J., and Domeney, A. M. (2000). Strain differences in the isolation-induced effects on prepulse inhibition of the acoustic startle response and on locomotor activity. Behav. Neurosci. 114, 364-373. doi: 10.1037/0735-7044.114.2.364.
    • (2000) Behav. Neurosci. , vol.114 , pp. 364-373
    • Weiss, I.C.1    Di Iorio, L.2    Feldon, J.3    Domeney, A.M.4
  • 109
    • 79956035968 scopus 로고    scopus 로고
    • Modulation of auditory and visual processing by Δ-9-tetrahydrocannabinol and cannabidiol: an FMRI study
    • doi: 10.1038/npp.2011.17
    • Winton-Brown, T. T., Allen, P., Bhattacharyya, S., Borgwardt, S. J., Fusar-Poli, P., Crippa, J. A., et al. (2011). Modulation of auditory and visual processing by Δ-9-tetrahydrocannabinol and cannabidiol: an FMRI study. Neuropsychopharmacology 36, 1340-1348. doi: 10.1038/npp.2011.17.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 1340-1348
    • Winton-Brown, T.T.1    Allen, P.2    Bhattacharyya, S.3    Borgwardt, S.J.4    Fusar-Poli, P.5    Crippa, J.A.6
  • 110
    • 84867555703 scopus 로고    scopus 로고
    • Atypical antipsychotics do not reverse prepulse inhibition deficits in acutely psychotic schizophrenia
    • doi: 10.1177/147323001204000425
    • Xue, Y. Y., Wang, H. N., Xue, F., and Tan, Q. R. (2012). Atypical antipsychotics do not reverse prepulse inhibition deficits in acutely psychotic schizophrenia. J. Int. Med. Res. 40, 1467-1475. doi: 10.1177/147323001204000425.
    • (2012) J. Int. Med. Res. , vol.40 , pp. 1467-1475
    • Xue, Y.Y.1    Wang, H.N.2    Xue, F.3    Tan, Q.R.4
  • 111
    • 84857363460 scopus 로고    scopus 로고
    • Long-lasting recovery of psychotic-like symptoms in isolation-reared rats after chronic but not acute treatment with the cannabinoid antagonist AM251
    • doi: 10.1017/S1461145710001185
    • Zamberletti, E., Vigano, D., Guidali, C., Rubino, T., and Parolaro, D. (2012). Long-lasting recovery of psychotic-like symptoms in isolation-reared rats after chronic but not acute treatment with the cannabinoid antagonist AM251. Int. J. Neuropsychopharmacol. 15, 267-280. doi: 10.1017/S1461145710001185.
    • (2012) Int. J. Neuropsychopharmacol. , vol.15 , pp. 267-280
    • Zamberletti, E.1    Vigano, D.2    Guidali, C.3    Rubino, T.4    Parolaro, D.5
  • 112
    • 1642523101 scopus 로고    scopus 로고
    • Selective antagonist [3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophrenia
    • doi: 10.1016/j.pnpbp.2003.11.005
    • Zavitsanou, K., Garrick, T., and Huang, X. F. (2004). Selective antagonist [3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 28, 355-360. doi: 10.1016/j.pnpbp.2003.11.005.
    • (2004) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.28 , pp. 355-360
    • Zavitsanou, K.1    Garrick, T.2    Huang, X.F.3
  • 113
    • 54249156391 scopus 로고    scopus 로고
    • Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action
    • doi: 10.1590/S1516-44462008000300015
    • Zuardi, A. W. (2008). Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action. Rev. Bras. Psiquiatr. 30, 271-280. doi: 10.1590/S1516-44462008000300015.
    • (2008) Rev. Bras. Psiquiatr. , vol.30 , pp. 271-280
    • Zuardi, A.W.1
  • 114
    • 78650624740 scopus 로고    scopus 로고
    • Cannabis sativa: the plant that can induce unwanted effects and also treat them
    • Zuardi, A. W., Crippa, J. A., and Hallak, J. E. (2010). Cannabis sativa: the plant that can induce unwanted effects and also treat them. Rev. Bras. Psiquiatr. 32(Suppl. 1), S1-S2.
    • (2010) Rev. Bras. Psiquiatr. , vol.32 , Issue.SUPPL. 1
    • Zuardi, A.W.1    Crippa, J.A.2    Hallak, J.E.3
  • 115
    • 84870833786 scopus 로고    scopus 로고
    • A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation
    • doi: 10.2174/138161212802884681
    • Zuardi, A. W., Crippa, J. A., Hallak, J. E., Bhattacharyya, S., Atakan, Z., Martin-Santos, R., et al. (2012). A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation. Curr. Pharm. Des. 18, 5131-5140. doi: 10.2174/138161212802884681.
    • (2012) Curr. Pharm. Des. , vol.18 , pp. 5131-5140
    • Zuardi, A.W.1    Crippa, J.A.2    Hallak, J.E.3    Bhattacharyya, S.4    Atakan, Z.5    Martin-Santos, R.6
  • 116
    • 33645821022 scopus 로고    scopus 로고
    • Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug
    • doi: 10.1590/S0100-879X2006000400001
    • Zuardi, A. W., Crippa, J. A., Hallak, J. E., Moreira, F. A., and Guimaraes, F. S. (2006). Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug. Braz. J. Med. Biol. Res. 39, 421-429. doi: 10.1590/S0100-879X2006000400001.
    • (2006) Braz. J. Med. Biol. Res. , vol.39 , pp. 421-429
    • Zuardi, A.W.1    Crippa, J.A.2    Hallak, J.E.3    Moreira, F.A.4    Guimaraes, F.S.5
  • 117
    • 70449375201 scopus 로고    scopus 로고
    • Cannabidiol for the treatment of psychosis in Parkinson's disease
    • doi: 10.1177/0269881108096519
    • Zuardi, A. W., Crippa, J. A., Hallak, J. E., Pinto, J. P., Chagas, M. H., Rodrigues, G. G., et al. (2009). Cannabidiol for the treatment of psychosis in Parkinson's disease. J. Psychopharmacol. 23, 979-983. doi: 10.1177/0269881108096519.
    • (2009) J. Psychopharmacol. , vol.23 , pp. 979-983
    • Zuardi, A.W.1    Crippa, J.A.2    Hallak, J.E.3    Pinto, J.P.4    Chagas, M.H.5    Rodrigues, G.G.6
  • 118
    • 0028881791 scopus 로고
    • Antipsychotic effect of cannabidiol
    • doi: 10.2174/138161212802884681
    • Zuardi, A. W., Morais, S. L., Guimaraes, F. S., and Mechoulam, R. (1995). Antipsychotic effect of cannabidiol. J. Clin. Psychiatry 56, 485-486. doi: 10.2174/138161212802884681.
    • (1995) J. Clin. Psychiatry , vol.56 , pp. 485-486
    • Zuardi, A.W.1    Morais, S.L.2    Guimaraes, F.S.3    Mechoulam, R.4


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