A QTL on rat chromosome 7 modulates prepulse inhibition, a neuro-behavioral trait of ADHD, in a Lewis x SHR intercross

Behavioral and Brain Functions

Volumn 2, Issue , 2006, Pages

  Vendruscolo, Leandro Franco ^a,b   Terenina Rigaldie, Elena ^a   Raba, Frantz ^a   Ramos, André ^b   Takahashi, Reinaldo Naoto ^b   Mormède, Pierre ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENTION DEFICIT DISORDER; CHROMOSOME 7; CONTROLLED STUDY; FEMALE; GENOTYPE; HOMOZYGOTE; MALE; NONHUMAN; PREPULSE INHIBITION; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; QUANTITATIVE TRAIT LOCUS MAPPING; RAT; RAT STRAIN; SENSORIMOTOR FUNCTION; SPONTANEOUSLY HYPERTENSIVE RAT; STARTLE REFLEX; STRAIN DIFFERENCE;

EID: 33746993534     PISSN: 17449081     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-9081-2-21     Document Type: Article

References (38)

1. Douglas VI: Cognitive control processes in attention-deficit/ hyperactivity disorder. In Handbook of disruptive behavior disorders Edited by: Quay HC, Hogan AE. New York: Kluwer Academic/Plenum; 1999:105-138.
2. Barkley RA: Theories of attention-deficit/hyperactivity disorder. In Handbook of disruptive behavior disorders Edited by: Quay HC, Hogan AE: New York: Kluwer Academic/Plenum; 1999:295-313.
3. Asherson P: Attention-Deficit Hyperactivity Disorder in the post-genomic era. Eur Child Adolesc Psychiatry 2004, 13:1/50-1/70.
4. Heiser P, Friedel S, Dempfle S, Konrad K, Smidt J, Grabarkiewicz J, Herpertz-Dahlmann B, Remschmidt H, Hebebrand J: Molecular genetic aspects of attention-deficit/hyperactivity disorder. Neurosc Biobehav Rev 2004, 28:625-641.
5. Biederman J, Faraone SV, Spencer T, Wilens T, Mick E, Lapey KA: Gender differences in a sample of adults with attention deficit hyperactivity disorder. Psychiatry Res 1994, 53:13-29.
6. Davids E, Zhang K, Tarazi FI, Baldessarini RJ: Animal models of attention-deficit hyperactivity disorder. Brain Res Rev 2003, 42:1-21.
7. Sagvolden T, Russell VA, Aase H, Johansen EB, Farshbaf M: Rodent models of attention-deficit hyperactivity disorder. Biol Psychiatry 2005, 57:1239-1247.
8. Ramos A, Berton O, Mormède P, Chaouloff F: A multiple-test study of anxiety-related behaviors in six inbred rat strains. Behav Brain Res 1997, 85:57-69.
9. Ramos A, Mellerin Y, Mormède P, Chaouloff F: A genetic and multifactorial analysis of anxiety-related behaviours in Lewis and SHR intercrosses. Behav Brain Res 1998, 96:195-205.
10. Ramos A, Kangerski AL, Basso PF, Da Silva Santos JE, Assreuy J, Vendruscolo LF, Takahashi RN: Evaluation of Lewis and SHR rat strain as a genetic model for the study of anxiety and pain. Behav Brain Res 2002, 129:113-123.
11. Ramos A, Moisan M-P, Chaouloff F, Mormède C, Mormède P: Identification of female specific QTLs affecting an emotionality-related behavior in rats. Mol Psychiatry 1999, 4:453-462.
12. Mormède P, Moneva E, Bruneval C, Chaouloff F, Moisan M-P: Marker-assisted selection of a neuro-behavioural trait related to behavioural inhibition in the SHR strain, an animal model of ADHD. Genes Brain Behav 2002, 1:111-116.
13. Hall CS: Emotional behavior in the rat. I. Defecation and urination as measures of individual differences in emotionality. J Comp Psychol 1934, 18:385-403.
14. Hall CS: Emotional behavior in the rat. III The relationship between emotionality and ambulatory activity. J Comp Psychol 1936, 22:345-452.
15. Bardo MT, Donohew RL, Harrington NG: Psychobiology of novelty seeking and drug seeking behavior. Behav Brain Res 1996. 77:23-43.
16. Koch M: The neurobiology of startle. Prog Neurobiol 1999, 59:107-128.
17. Swerdlow NR, Braff DL, Taaid N, Geyer MA: Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients. Arch Gen Psychiatry 1994, 51:139-154.
18. Castellanos FX, Fine EJ, Kaysen D, Marsh WL, Rapoport JL, Hallett M: Sensorimotor gating in boys with Tourette's syndrome and ADHD: preliminary results. Biol Psychiatry 1996, 39:33-41.
19. Hawk LW Jr, Yartz AR, Pelham WE Jr, Lock TM: The effects of methylphenidate on prepulse inhibition during attended and ignored prestimuli among boys with attention-deficit hyperactivity disorder. Psychopharmacology 2003, 165:118-127.
20. Swerdlow NR, Braff DL, Caine SB, Geyer MA: Limbic cortico-striato-pallido-pontine substrates of sensorimotor gating in animal models and psychiatric disorders. In Limbic Motor Circuits and Neuropsychiatry Edited by: Kalivas PW, Barnes CD. Boca Raton: CRC Press; 1993:311-328.
21. Swerdlow NR, Geyer MA, Braff DL: Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges. Psychopharmacology 2001, 156:194-215.
22. Davis M: Are different parts of the extended amygdale involved in fear versus anxiety? Biol Psychiatry 1998, 44:1239-1247.
23. Bennett B, Beeson M, Gordon L, Johnson TE: Quick method for confirmation of quantitative trait loci. Alcohol Clin Exp Res 1997, 21:767-772.
24. Vendruscolo LF, Terenina-Rigaldie E, Raba F, Ramos A, Takahashi RN, Mormède P: Evidence for a female-specific effect of a chromosome 4 locus on anxiety-related behaviors and ethanol drinking in rats. Genes Brain Behav in press.
25. Härd E, Carlsson SG, Jern S, Larsson K, Lindh A, Svensson L: Behavioral reactivity in spontaneously hypertensive rats. Physiol Behav 1985, 35:487-492.
26. van den Buuse M: Prepulse inhibition of acoustic startle in spontaneously hypertensive rats. Behav Brain Res 2004, 154:331-337.
27. Braff DL, Grillon C, Geyer MA: Gating and habituation of the startle reflex in schizophrenic patients. Arch Gen Psychiatry 1992, 49:206-215.
28. Grillon C, Dierker L, Merikangas KR: Startle modulation in children at risk for anxiety disorders and/or alcoholism. J Am Acad Adolesc Psychiatry 1997, 36:925-932.
29. Da Silva GE, Vendruscolo LF, Takahashi RN: Effects of ethanol on locomotor and anxiety-like behaviors and the acquisition of ethanol intake in Lewis and spontaneously hypertensive rats. Life Sci 2005, 77:693-706.
30. Palmer AA, Dulawa SC, Mottiwala AA, Conti LH, Geyer MA, Printz MP: Prepulse Startle Deficit in the Brown Norway Rat: A Potential Genetic Model. Behav Neurosc 2000, 114:374-388.
31. Yamashita M, Fukushima S, Shen HW, Hall FS, Uhl GR, Numachi Y, Kobayashi H, Sora I: Norepinephrine Transporter Blockade can Normalize the Prepulse Inhibition Deficits found in Dopamine Transporter Knockout Mice. Neuropsychopharmacology in press.
32. Paylor R, Crawley JN: Inbred strain differences in prepulse inhibition of the mouse startle response. Psychopharmacology 1997, 132:169-180.
33. Swerdlow NR, Krupin AS, Bongiovanni MJ, Shoemaker JM, Goins JC, Hammer RP Jr: Heritable Differences in the Dopaminergic Regulation of Behavior in Rats: Relationship to D2-Like Receptor G-Protein Function. Neuropsychopharmacology in press.
34. Palmer AA, Breen LL, Flodman P, Conti LH, Spence MA, Printz MP: Identification of quantitative trait loci for prepulse inhibition in rats. Psychopharmacology 2003, 165:270-279.
35. Joober R, Zarate J-M, Rouleau G-A, Skamene E, Boksa P: Provisional mapping of quantitative trait loci modulating the acoustic startle response and prepulse inhibition of acoustic startle. Neuropsychopharmacology 2002, 27:765-781.
36. Petryshen TL, Kirby A, Hammer RP Jr, Purcell S, Singer JB, Hill AE, Nadeau JH, Daly MJ, Sklar P: Two quantitative trait Loci for prepulse inhibition of startle identified on mouse chromosome 16 using chromosome substitution strains. Genetics 2005, 171:1985-1904.
37. Kao HT, Porton B, Czernik AJ, Feng J, Yiu G, Häring M, Benfenati F, Greengard P: A third member of the synapsin gene family. Proc Natl Acad Sci 1998, 95:4667-4672.
38. Porton B, Ferreira A, DeLisi LE, Kao HT: A rare polymorphism affects a mitogen-activated protein kinase site in synapsin III: possible relationship to schizophrenia. Biol Psychiatry 2004, 55:118-125.