Regulation of hepatic drug transporter activity and expression by organochlorine pesticides

Journal of Biochemical and Molecular Toxicology

Volumn 28, Issue 3, 2014, Pages 119-128

  Bucher, Simon ^a   Le Vee, Marc ^a   Jouan, Elodie ^a   Fardel, Olivier ^a,b  

^a UNIVERSITÉ DE RENNES 1   (France)

^b RENNES UNIVERSITY HOSPITAL   (France)

Author keywords

Drug transporter; Efflux; Influx; Liver; Organochlorines; Pesticides; Regulation

Indexed keywords

ABC TRANSPORTER; BREAST CANCER RESISTANCE PROTEIN; CARRIER PROTEINS AND BINDING PROTEINS; CHLORDANE; CHLORDECONE; CHLORPHENOTANE; CYTOCHROME P450 3A4; DIELDRIN; DRUG METABOLIZING ENZYME; DRUG TRANSPORTER; ENDOSULFAN; HEPTACHLOR; LINDANE; MESSENGER RNA; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; ORGANIC CATION TRANSPORTER 1; ORGANOCHLORINE PESTICIDE; SODIUM BILE ACID COTRANSPORTER; UNCLASSIFIED DRUG; VERAPAMIL; ABCB1 PROTEIN, HUMAN; ABCG2 PROTEIN, HUMAN; CARRIER PROTEIN; CHLORINATED HYDROCARBON; COTRANSPORTER; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2; ORGANIC ANION TRANSPORTER; PESTICIDE; SLCO1B1 PROTEIN, HUMAN; SLCO2B1 PROTEIN, HUMAN; SODIUM-BILE ACID COTRANSPORTER; TUMOR PROTEIN;

ARTICLE; CELL STRAIN HEK293; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG TRANSPORT; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; PROTEIN EXPRESSION; CELL LINE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; DRUG INACTIVATION; GENE EXPRESSION REGULATION; GENETICS; LIVER; MCF 7 CELL LINE; METABOLISM;

ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; CELL SURVIVAL; GENE EXPRESSION REGULATION; HUMANS; HYDROCARBONS, CHLORINATED; INACTIVATION, METABOLIC; LIVER; MCF-7 CELLS; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; ORGANIC ANION TRANSPORTERS; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; ORGANIC CATION TRANSPORTER 1; P-GLYCOPROTEIN; P-GLYCOPROTEINS; PESTICIDES; SYMPORTERS;

EID: 84895490806     PISSN: 10956670     EISSN: 10990461     Source Type: Journal    
DOI: 10.1002/jbt.21543     Document Type: Article

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