Benzo[a]pyrene increases DNA double strand break repair in vitro and in vivo: A possible mechanism for benzo[a]pyrene-induced toxicity

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 760, Issue , 2014, Pages 64-69

  Tung, Emily W Y ^a   Philbrook, Nicola A ^a   Belanger, Christine L ^a   Ansari, Saad ^a   Winn, Louise M ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

H2AX; Benzo a pyrene; DNA double strand break; Homologous recombination; Nonhomologous end joining; Reactive oxygen species

Indexed keywords

ATM PROTEIN; ATM PROTEIN, MOUSE; BENZO[A]PYRENE; BETA GALACTOSIDASE; CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN; KU ANTIGEN; PROTEIN P53;

ANIMAL; CHO CELL LINE; CRICETULUS; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HAMSTER; HOMOLOGOUS RECOMBINATION; KIDNEY; LIVER; LUNG; MALE; METABOLISM; MOUSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPLEEN; THYMUS; TOXICITY; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; ANTIGENS, NUCLEAR; ATAXIA TELANGIECTASIA MUTATED PROTEINS; BENZO(A)PYRENE; BETA-GALACTOSIDASE; BLOTTING, WESTERN; CHO CELLS; CRICETINAE; CRICETULUS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-BINDING PROTEINS; GENE EXPRESSION; HOMOLOGOUS RECOMBINATION; KIDNEY; LIVER; LUNG; MALE; MICE; MICE, TRANSGENIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPLEEN; THYMUS GLAND; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84895066085     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2013.12.003     Document Type: Article

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