Carcinogenicity of benzo[a]pyrene and manufactured gas plant residues in infant mice

Carcinogenesis

Volumn 18, Issue 1, 1997, Pages 127-135

  Rodriguez, Lewis V ^a   Dunsford, Harold A ^b   Steinberg, Michael ^c   Chaloupka, Kathy K ^c   Zhu, Lunjian ^d   Safe, Stephen ^c   Womack, James E ^c   Goldstein, Lawrence S ^e  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b SABA UNIVERSITY SCHOOL OF MEDICINE   (Netherlands)

^c TEXAS A AND M UNIVERSITY   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e ELECTRIC POWER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE; CARCINOGEN; PHOSPHORUS 32; POLYCYCLIC AROMATIC HYDROCARBON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DOSE TIME EFFECT RELATION; FEMALE; FORESTOMACH; GAS; LIVER CARCINOGENESIS; LUNG; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BENZO(A)PYRENE; CARCINOGENICITY TESTS; COAL TAR; DNA ADDUCTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; LIVER NEOPLASMS, EXPERIMENTAL; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; NEOPLASMS, EXPERIMENTAL; ORGAN SIZE; SEX FACTORS; STOMACH NEOPLASMS;

EID: 0031427594     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/18.1.127     Document Type: Article

References (60)

1. Goldstein,L.S., Safe,S. and Weyand,E.H. (1994) Carcinogenicity of coal tars: A multidisciplinary approach. Polycyclic Aromatic Compounds, 7, 161-174.
2. Wyzga,R.E. and Goldstein,L.S. (1994) Assessing the carcinogen potency of environmental coal tars, by-products of coal gasification. In Yang,R.S.H. (ed.), Toxicology of Chemical Mixtures. Academic Press Inc., San Diego, CA, pp. 83-97.
3. 3.IARC (1984) Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 34. Polycyclic Aromatic Compounds. Part 3. Industrial Exposure in Aluminium Production, Coal Gasification, Coke Production, and Iron and Steel Founding. IARC, Lyon, France.
4. 4.IARC (1985) Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 35. Polycyclic Aromatic Compounds. Part 4. Bitumens, Coal-tars and Derived Products, Shale-oils and Soots. IARC, Lyon, France.
5. Fisher,R.E.W. (1953) Occupational skin cancer in a group of tar workers. Arch. Indust. Hyg., 7, 12-18.
6. Pittelkow,M.R., Perry,H.O., Muller,S.A., Maughan,W.Z. and O'Brien,P.C. (1981) Skin cancer in patients with psoriasis treated with coal tar: a 25-year follow-up study. Arch. Dermatol., 117, 465-468.
7. Comaish,J.S. (1987) The effect of tar and ultraviolet on the skin. J. Invest. Dermatol., 88, 61-64.
8. Warshawsky,D., Barkley,W. and Bingham,E. (1993) Factors affecting carcinogenic potential of mixtures. Fund. Appl. Toxicol., 20, 376-382.
9. 1 mice. J. Toxicol. Environ. Health, 42, 89-107.
10. Weyand,E.H., Chen,Y.-C., Wu,Y., Koganti,A., Dunsford,H.A. and Rodriguez,L.V. (1995) Differences in the tumorigenic activity of a pure hydrocarbon and a complex mixture following ingestion: Benzo[a]pyrene vs manufactured gas plant residue. Chem. Res. Toxicol., 6, 949-954.
11. Wallcave,L., Garcia,H., Feldman,R., Lijinksky,W. and Shubik,P (1971) Skin tumorigenesis in mice by petroleum asphalts and coal-tar pitches of known polynuclear aromatic hydrocarbon content. Toxicol. Applied Pharmacol., 18, 41-52.
12. Mahlum,D.D., Wright,C.W., Chess,E.K. and Wilson,B.W. (1984) Fractionation of skin tumor-initiating activity of coal liquids. Cancer Res., 44, 5176-5181.
13. Robinson,M., Bull,R.J., Munch,J. and Meier,J. (1984) Comparative carcinogenic and mutagenic activity of coal tar and petroleum asphalt paints used in potable water supply systems. J. Appl. Toxicol., 4, 49-56.
14. Mukhtar,H., Mukul,D. and Bickers,D.R. (1986) Skin tumor initiating activity of therapeutic crude coal tar as compared to other polycyclic aromatic hydrocabons in Sencar mice. Cancer Lett., 31, 147-151.
15. 15.United States Environmental Protection Agency (1991) Workshop Report on Toxicity Equivalency Factors for Polychlorinated Biphenyl Congeners (Risk Assessment Forum). EPA/625/3-91/020.
16. Dunsford,H.A., Womack,J.E., Ramagli,L.S., Sell,S., Becker,F.F. and Rodriguez,L.V. (1991) Spontaneous hepatocarcinogenesis in recombinant inbred mouse strains: correlation with serum levels of Alpha-Fetoprotein. J. Tumor Marker Oncol., 6, 145-155.
17. Dunsford,H.A., Womack,J.E., Ramagli,L.S., Sell,S., Becker,F.F. and Rodriguez,L.V. (1991) Diethylnitrosamine-induced hepatocarcinogenesis in recombinant inbred mouse strains: correlation with serum levels of Alpha-Fetoprotein. J. Tumor Marker Oncol., 6, 157-164.
18. Vesselinovitch,S.D. and Mihailovich,N. (1967) The neonatal and infant age periods as biologic factors which modify multicarcinogenesis by urethan. Cancer Res., 27, 1422-1429.
19. Vesselinovitch,S.D, Mihailovich,N. and Pietra,G. (1967) The prenatal exposure of mice to urethan and the consequent development of tumors in various tissues. Cancer Res., 27, 2333-2337.
20. Vesselinovitch,S.D., Mihailovich,N., Rao,K.V.N. and Itze,L. (1971) Perinatal carcinogenesis by urethan. Cancer Res., 31, 2143-2147.
21. Vesselinovitch,S.D., Rao,K.V.N. and Mihailovich,N. (1979) Neoplastic response of mouse tissues during perinatal age periods and its significance in chemical carcinogenesis. Natl Cancer Inst. Monogr., 51, 239-250.
22. Vesselinovitch,S.D., Koka,M., Rao,K.V.N., Mihailovich,N. and Rice,J.M. (1977) Prenatal multi-carcinogenesis by ethylnitorsourea in mice. Cancer Res., 37, 1822-1828.
23. Itze,L., Vesselinovitch,S.D. and Rao,K.V.N. (1976) Inter and intra diurnal variations. DNA, RNA, and protein synthetic activity in newborn, infant and young adult mouse livers. Physiol. Biochem., 25, 289-293.
24. Vesselinovitch,S.D., Koka,M., Mihailovich,N. and Rao,K.V.N. (1984) Carcinogenicity of diethyl-nitrosamine in newborn, infant and adult mice. J. Cancer Res. Clin. Oncol., 108, 60-65.
25. Vesselinovitch,S.D. (1990) Perinatal mouse liver carcinogenesis as a sensitive carcinogenesis model and the role of the sex hormonal environment in tumor development. In Stevenson,D.E., Popp,J.A., Ward,J.M., McLain,R.M., Slaga,T.J. and Pitot,H.C. (eds). Mouse Liver Carcinogenesis: Mechanisms and Species Comparisons. Alan R.Liss, Inc., New York, pp. 53-68.
26. Vesselinovitch,S.D., Kyriazis,A.P., Mihailovich,N. and Rao,K.V.N. (1975) Conditions modifying development of tumors in mice at various sites by benzo[a]pyrene. Cancer Res., 35, 2948-2953.
27. Becker,F.F. (1982) Morphological classification of mouse liver tumors based on biological characteristics. Cancer Res., 42, 3918-3923.
28. Becker,F.F. (1985) Tumor phenotype and susceptibility to progression as an expression of subpopulations of initiated murine cells. Cancer Res., 45, 768-773.
29. 1 mice. Cancer Res., 38, 2003-2010.
30. Ward,J.M. and Vlahakis,G. (1978) Evaluation of hepatocellular neoplasms in mice. J. Natl Cancer Inst., 61, 807-811.
31. Ward,J.M., Griesemer,R.A. and Weisburger,J.H. (1979) The mouse liver tumor as an endpoint in carcinogenesis tests. Toxicol. Appl. Pharmacol., 51, 389-397.
32. 1 mice. Cancer Lett., 9, 319-325.
33. 32P-postlabeling test for structurally diverse adducts. Carcinogenesis, 7, 1542-1551.
34. 32P postlabeling assay, J. Natl Cancer Inst., 81, 341-347.
35. 32P postlabeling analysis of aromatic carcinogen: DNA adducts. Cancer Res., 45, 5656-5662.
36. Randerath,E. and Randerath,K. (1967) Thin-layer separation methods for nucleic acid derivatives. Methods Enzymol., 12A, 323-347.
37. Leadon,S.A., Sumcrel,J., Minton,T.A. and Tischler,A. (1995) Coal tar residues produce both DNA adducts and oxidative DNA damage in human mammary epithelial cells. Carcinogenesis, 16, 3021-3026.
38. Ripp,J., Taylor,B., Mauro,D. and Young,M. (1993) Chemical and physical characteristics of tar samples from selected manufactured gas plant (MGP) sites. Electrical Power Research Institute, Research Project 2879-12, TR-102184.
39. Safe,S., Rodriguez,L.V. and Goldstein,L.S. (1995) Toxic equivalency factor approach for risk assessment of combustion by-products. Toxicol, Environ. Chem., 49, 181-191.
40. Chaloupka,K., Harper,N., Krishnan,V., Santostefano,M., Rodriguez,L.V. and Safe,S. (1993) Synergistic activity of polynuclear aromatic hydrocarbon mixtures as aryl hydrocarbon (Ah) receptor agonists. Chem.-Biol. interactions, 89, 141-158.
41. Abelson,P.H. (1995) Flaws in risk assessment. Science, 270, 215.
42. Warshawsky,D., Barkley,W., Miller,M.L., LaDow,K. and Andringa,A. (1994) Carcinogenicity of 7H-dibenzo[c,g]carbazole, dibenz[a,j]acridine and benzo[a]pyrene in mouse skin and liver following topical application. Toxicology, 93, 135-149.
43. Chaloupka,K., Steinberg,M., Santostefano,M., Rodriguez,L.V., Goldstein,L. and Safe,S. (1995) Induction of Cypla-1 and Cypla-2 gene expression by a reconstituted mixture of polynuclear aromatic hydrocarbons in B6C3F1 mice. Chem.-Biol. Interactions, 96, 207-221.
44. Vesselinovitch,S.D., Rao,K.V.N., Mihailovich,N. and Rice,J.M. (1974) Development of broad spectrum of tumors by ethylnitrosourea in mice; modifying role of age, sex, and strain. Cancer Res., 34, 2530-2538.
45. Vesselinovitch,S.D., Kyriazis,A.P., Mihailovich,N. and Rao,K.V.N. (1975a) Factors influencing augmentation and/or acceleration of lymphoreticular tumors in mice by benzo[a]pyrene. Cancer Res., 35, 1963-1969.
46. 14C]dimethylnitrosamine in hydroxyurea-synchronized regenerating rat liver. Cancer Res., 39, 4228-4236.
47. Dunsford,H.A., Zhu,L., Chaloupka,K.K., Steinberg,M., Safe,S., Womack,J.E., Goldstein,L.S. and Rodriguez,L.V. (1994) Induction of transient cell proliferation by manufactured gas plant residue in B6C3F1 male mice. Polyc. Arom. Comp., 7, 183-189.
48. Grasso,P. and Hardy,J. (1975) Strain difference in natural incidence and response to carcinogens. In Butler,W.H. and Newberene,P.M. (eds), Mouse Hepatic Neoplasia. Elsevier Science Publishing Co., Amsterdam, pp. 111-132.
49. Drinkwater,N.R. and Ginsler,J.J. (1986) Genetic control of hepatocarcinogenesis in C57BL/6J and C3H/HeJ inbred mice. Carcinogenesis, 7, 1701-1707.
50. Diwan,B.A., Rice,J.M., Ohshima,M. and Ward,J.M. (1986) Interstrain differences in susceptibility to liver carcinogenesis initiated by N-nitroso-diethylamine and its promotion by phenobarbital in C57BL/6NCr, C3H/ HeNCr and DBA/2NCr mice. Carcinogenesis, 7, 215-220.
51. Lee,G.-H., Nomura,K. and Kitagawa,T. (1989) Comparative study of diethylnitrosamine-initiated two-stage hepatocarcinogenesis in C3H, C57BL and BALB mice promoted by various hepatopromoters. Carcinogenesis, 10, 2227-2230.
52. Ward,J.M., Diwan,B.A., Lubet,R.A., Henneman,J.R. and Devor,D.E. (1990) Liver tumor promoters and other mouse liver carcinogens. In Stevenson,D.E., Popp,J.A., Ward,J.M., McLain,R.M., Slaga,J.J. and Pitot,H.C. (eds). Mouse Liver Carcinogenesis: Mechanisms and Species Comparisons. Alan R.Liss, New York, pp. 85-108.
53. Vesselinovitcb,S.D., Itze,L., Mihailovich,N. and Rao,K.V.N. (1980) Modifying role of partial hepatectomy and gonadectomy in ethylnitrosourea-induced hepatocarcinogenesis. Cancer Res., 40, 1538-1542.
54. Diwan,B.A., Rice,J.M. and Ward,J.M. (1990) Strain-dependent effects of phenobarbital on liver tumor promotion in inbred mice. In Stevenson,D.E., Popp,J.A., Ward,J.M., McLain,R.M., Slaga,T.J. and Pitot,H.C. (eds). Mouse Liver Carcinogenesis: Mechanisms and Species Comparisons. Alan R.Liss, New York, pp. 69-83.
55. Hashimoto,Y., Degawa,M., Kojima,M. and Hishinuma,T. (1982) Induction of carcinogen activation enzyme(s) by feeding of a carcinogenic tryptophan pyrolysate correlates to sex difference in the Carcinogenesis of the mouse. Gann, 73, 508-510.
56. Williams,G.M. (1982) Sex hormones and liver cancer. Lab. Invest., 46, 352-354.
57. Vesselinovitch,S.D., Mihailovich,N. and Negri,N. (1988) Sex hormones as modulators of liver tumor development. In Roberfrold,M.B. and Preat,V. (eds), Experimental Hepatocarcinogenesis. Plenum Publishing, New York, pp. 51-62.
58. Kemp,C.J. and Drinkwater,N.R. (1989) Genetic variation in liver tumor susceptibility, plasma testosterone levels, and androgen receptor binding in six inbred strains of mice. Cancer Res., 49, 5044-5047.
59. Weyand,E.H. and Wu,Y. (1995) Covalent binding of polycyclic aromatic hydrocarbon components of manufacatured gas plant residue to mouse lung and forestomach DNA. Chem. Res, Toxicol., 8, 955-962.
60. Culp,S.J. and Beland,F.A. (1994) Comparison of DNA adduct formation in mice fed coal tar or benzo[a]pyrene. Carcinogenesis, 15, 247-252.