Induction of Rad51 protein levels by p38 MAPK decreases cytotoxicity and mutagenicity in benzo[a]pyrene-exposed human lung cancer cells

Toxicology and Applied Pharmacology

Volumn 230, Issue 3, 2008, Pages 290-297

  Chuang, Show Mei ^a   Wang, Lyu Han ^b   Hong, Jhao Hao ^b   Lin, Yun Wei ^b  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b NATIONAL CHIAYI UNIVERSITY   (Taiwan)

Author keywords

B a P; Cytotoxicity; DNA repair; Mutagenicity; p38 MAPK; Proteasome; Rad51; Ubiquitin

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BENZO[A]PYRENE; CARCINOGEN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE P38; POLYCYCLIC HYDROCARBON; RAD51 PROTEIN; SMALL INTERFERING RNA;

ARTICLE; CANCER CELL; CARCINOGENESIS; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; MUTAGENICITY; PROTEIN INDUCTION; PROTEIN STABILITY; PROTEIN SYNTHESIS; RNA TRANSCRIPTION;

BENZO(A)PYRENE; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MUTAGENS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEASOME ENDOPEPTIDASE COMPLEX; RAD51 RECOMBINASE; RNA, MESSENGER;

MAMMALIA;

EID: 46749085843     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.03.001     Document Type: Article

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