-
2
-
-
77950635525
-
Can antigen-specific regulatory T cells protect against graft versus host disease and spare anti-malignancy alloresponse
-
Pidala J, Anasetti C., Can antigen-specific regulatory T cells protect against graft versus host disease and spare anti-malignancy alloresponse ? Haematologica 2010; 95: 660-665.
-
(2010)
Haematologica
, vol.95
, pp. 660-665
-
-
Pidala, J.1
Anasetti, C.2
-
3
-
-
79954551032
-
Mechanisms of tolerance
-
Bluestone JA., Mechanisms of tolerance. Immunol Rev 2011; 241: 5-19.
-
(2011)
Immunol Rev
, vol.241
, pp. 5-19
-
-
Bluestone, J.A.1
-
4
-
-
0027397169
-
Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1
-
Tan P, Anasetti C, Hansen JA, et al. Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1. J Exp Med 1993; 177: 165-173.
-
(1993)
J Exp Med
, vol.177
, pp. 165-173
-
-
Tan, P.1
Anasetti, C.2
Hansen, J.A.3
-
5
-
-
0028903939
-
CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2
-
Sayegh MH, Akalin E, Hancock WW, et al. CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2. J Exp Med 1995; 181: 1869-1874.
-
(1995)
J Exp Med
, vol.181
, pp. 1869-1874
-
-
Sayegh, M.H.1
Akalin, E.2
Hancock, W.W.3
-
6
-
-
0028425450
-
In vitro induction of T cell anergy by blocking B7 and early T cell costimulatory molecule ETC-1/B7-2
-
Chen C, Nabavi N., In vitro induction of T cell anergy by blocking B7 and early T cell costimulatory molecule ETC-1/B7-2. Immunity 1994; 1: 147-154.
-
(1994)
Immunity
, vol.1
, pp. 147-154
-
-
Chen, C.1
Nabavi, N.2
-
7
-
-
0029945316
-
Complete blockade of B7 family-mediated costimulation is necessary to induce human alloantigen-specific anergy: A method to ameliorate graft-versus-host disease and extend the donor pool
-
Gribben JG, Guinan EC, Boussiotis VA, et al. Complete blockade of B7 family-mediated costimulation is necessary to induce human alloantigen-specific anergy: A method to ameliorate graft-versus-host disease and extend the donor pool. Blood 1996; 87: 4887-4893.
-
(1996)
Blood
, vol.87
, pp. 4887-4893
-
-
Gribben, J.G.1
Guinan, E.C.2
Boussiotis, V.A.3
-
8
-
-
0035806276
-
CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade
-
Taylor PA, Noelle RJ, Blazar BR., CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade. J Exp Med 2001; 193: 1311-1318.
-
(2001)
J Exp Med
, vol.193
, pp. 1311-1318
-
-
Taylor, P.A.1
Noelle, R.J.2
Blazar, B.R.3
-
9
-
-
0033519661
-
Transplantation of anergic histoincompatible bone marrow allografts
-
Guinan EC, Boussiotis VA, Neuberg D, et al. Transplantation of anergic histoincompatible bone marrow allografts. N Engl J Med 1999; 340: 1704-1714.
-
(1999)
N Engl J Med
, vol.340
, pp. 1704-1714
-
-
Guinan, E.C.1
Boussiotis, V.A.2
Neuberg, D.3
-
10
-
-
55249127599
-
Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: Results of 2 phase 1 studies
-
Davies JK, Gribben JG, Brennan LL, Yuk D, Nadler LM, Guinan EC., Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: Results of 2 phase 1 studies. Blood 2008; 112: 2232-2241.
-
(2008)
Blood
, vol.112
, pp. 2232-2241
-
-
Davies, J.K.1
Gribben, J.G.2
Brennan, L.L.3
Yuk, D.4
Nadler, L.M.5
Guinan, E.C.6
-
11
-
-
0037097593
-
Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40: CD40L costimulatory pathway results in the generation of a potent immune regulatory cell
-
Taylor PA, Friedman TM, Korngold R, Noelle RJ, Blazar BR., Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40: CD40L costimulatory pathway results in the generation of a potent immune regulatory cell. Blood 2002; 99: 4601-4609.
-
(2002)
Blood
, vol.99
, pp. 4601-4609
-
-
Taylor, P.A.1
Friedman, T.M.2
Korngold, R.3
Noelle, R.J.4
Blazar, B.R.5
-
12
-
-
0034657951
-
Blockade of CD86 and CD40 induces alloantigen-specific immunoregulatory T cells that remain anergic even after reversal of hyporesponsiveness
-
Koenen HJ, Joosten I., Blockade of CD86 and CD40 induces alloantigen-specific immunoregulatory T cells that remain anergic even after reversal of hyporesponsiveness. Blood 2000; 95: 3153-3161.
-
(2000)
Blood
, vol.95
, pp. 3153-3161
-
-
Koenen, H.J.1
Joosten, I.2
-
13
-
-
2142825777
-
Human T cell activation by costimulatory signal-deficient allogeneic cells induces inducible costimulator-expressing anergic T cells with regulatory cell activity
-
Vermeiren J, Ceuppens JL, Van Ghelue M, et al. Human T cell activation by costimulatory signal-deficient allogeneic cells induces inducible costimulator-expressing anergic T cells with regulatory cell activity. J Immunol 2004; 172: 5371-5378.
-
(2004)
J Immunol
, vol.172
, pp. 5371-5378
-
-
Vermeiren, J.1
Ceuppens, J.L.2
Van Ghelue, M.3
-
14
-
-
84869758998
-
Ex vivo alloanergization with belatacept: A strategy to selectively modulate alloresponses after transplantation
-
Davies JK, Barbon CM, Voskertchian A, Nadler LM, Guinan EC., Ex vivo alloanergization with belatacept: A strategy to selectively modulate alloresponses after transplantation. Cell Transplant 2012; 21: 2047-2061.
-
(2012)
Cell Transplant
, vol.21
, pp. 2047-2061
-
-
Davies, J.K.1
Barbon, C.M.2
Voskertchian, A.3
Nadler, L.M.4
Guinan, E.C.5
-
15
-
-
77954670464
-
Expansion of allospecific regulatory T cells after anergized, mismatched bone marrow transplantation
-
Davies JK, Nadler LM, Guinan EC., Expansion of allospecific regulatory T cells after anergized, mismatched bone marrow transplantation. Sci Transl Med 2009; 1: 1ra3.
-
(2009)
Sci Transl Med
, vol.1
-
-
Davies, J.K.1
Nadler, L.M.2
Guinan, E.C.3
-
16
-
-
0037093217
-
The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality
-
Taylor PA, Lees CJ, Blazar BR., The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality. Blood 2002; 99: 3493-3499.
-
(2002)
Blood
, vol.99
, pp. 3493-3499
-
-
Taylor, P.A.1
Lees, C.J.2
Blazar, B.R.3
-
18
-
-
78751696183
-
Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: Safety profile and detection kinetics
-
Brunstein CG, Miller JS, Cao Q, et al. Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: Safety profile and detection kinetics. Blood 2011; 117: 1061-1070.
-
(2011)
Blood
, vol.117
, pp. 1061-1070
-
-
Brunstein, C.G.1
Miller, J.S.2
Cao, Q.3
-
19
-
-
79953809817
-
Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
-
Di Ianni M, Falzetti F, Carotti A, et al. Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. Blood 2011; 117: 3921-3928.
-
(2011)
Blood
, vol.117
, pp. 3921-3928
-
-
Di Ianni, M.1
Falzetti, F.2
Carotti, A.3
-
20
-
-
0346366991
-
+ T cells that require antigen-specific activation for suppression
-
+ T cells that require antigen-specific activation for suppression. J Immunol 2003; 171: 6431-6441.
-
(2003)
J Immunol
, vol.171
, pp. 6431-6441
-
-
Koenen, H.J.1
Fasse, E.2
Joosten, I.3
-
23
-
-
84857026191
-
Rapamycin generates graft-homing murine suppressor CD8(+) T cells that confer donor-specific graft protection
-
El Essawy B, Putheti P, Gao W, Strom TB., Rapamycin generates graft-homing murine suppressor CD8(+) T cells that confer donor-specific graft protection. Cell Transplant 2011; 20: 1759-1769.
-
(2011)
Cell Transplant
, vol.20
, pp. 1759-1769
-
-
El Essawy, B.1
Putheti, P.2
Gao, W.3
Strom, T.B.4
-
24
-
-
29244482759
-
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
-
Tang Q, Adams JY, Tooley AJ, et al. Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol 2006; 7: 83-92.
-
(2006)
Nat Immunol
, vol.7
, pp. 83-92
-
-
Tang, Q.1
Adams, J.Y.2
Tooley, A.J.3
-
25
-
-
59749086849
-
Distribution of Foxp3(+) T-regulatory cells in experimental autoimmune neuritis rats
-
Zhang Z, Zhang ZY, Fauser U, Schluesener HJ., Distribution of Foxp3(+) T-regulatory cells in experimental autoimmune neuritis rats. Exp Neurol 2009; 216: 75-82.
-
(2009)
Exp Neurol
, vol.216
, pp. 75-82
-
-
Zhang, Z.1
Zhang, Z.Y.2
Fauser, U.3
Schluesener, H.J.4
-
29
-
-
70349247894
-
Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects
-
Zhang Z, Zhang ZY, Schluesener HJ., Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects. J Immunol 2009; 183: 3081-3091.
-
(2009)
J Immunol
, vol.183
, pp. 3081-3091
-
-
Zhang, Z.1
Zhang, Z.Y.2
Schluesener, H.J.3
-
32
-
-
56049106841
-
Induction of alloanergy in human donor T cells without loss of pathogen or tumor immunity
-
Davies JK, Yuk D, Nadler LM, Guinan EC., Induction of alloanergy in human donor T cells without loss of pathogen or tumor immunity. Transplantation 2008; 86: 854-864.
-
(2008)
Transplantation
, vol.86
, pp. 854-864
-
-
Davies, J.K.1
Yuk, D.2
Nadler, L.M.3
Guinan, E.C.4
-
33
-
-
0033621780
-
P27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes
-
Boussiotis VA, Freeman GJ, Taylor PA, et al. p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes. Nat Med 2000; 6: 290-297.
-
(2000)
Nat Med
, vol.6
, pp. 290-297
-
-
Boussiotis, V.A.1
Freeman, G.J.2
Taylor, P.A.3
-
34
-
-
0035202540
-
Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells
-
Tzachanis D, Freeman GJ, Hirano N, et al. Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells. Nat Immunol 2001; 2: 1174-1182.
-
(2001)
Nat Immunol
, vol.2
, pp. 1174-1182
-
-
Tzachanis, D.1
Freeman, G.J.2
Hirano, N.3
-
35
-
-
0014792798
-
Cell interactions in the induction of tolerance: The role of thymic lymphocytes
-
Gershon RK, Kondo K., Cell interactions in the induction of tolerance: The role of thymic lymphocytes. Immunology 1970; 18: 723-737.
-
(1970)
Immunology
, vol.18
, pp. 723-737
-
-
Gershon, R.K.1
Kondo, K.2
-
37
-
-
57149108306
-
+ T lymphocytes in human peripheral blood increases with age
-
+ T lymphocytes in human peripheral blood increases with age. J Leukoc Biol 2008; 84: 1454-1461.
-
(2008)
J Leukoc Biol
, vol.84
, pp. 1454-1461
-
-
Simone, R.1
Zicca, A.2
Saverino, D.3
-
38
-
-
71249132533
-
- T-suppressor cells in adult-to-adult living donor liver transplant recipients
-
- T-suppressor cells in adult-to-adult living donor liver transplant recipients. Transplant Proc 2009; 41: 4229-4231.
-
(2009)
Transplant Proc
, vol.41
, pp. 4229-4231
-
-
Lin, Y.X.1
Yan, L.N.2
Li, B.3
-
39
-
-
38149086827
-
+ T cells in alemtuzumab-depleted kidney transplant recipients treated with reduced immunosuppression
-
+ T cells in alemtuzumab-depleted kidney transplant recipients treated with reduced immunosuppression. Am J Transplant 2008; 8: 338-347.
-
(2008)
Am J Transplant
, vol.8
, pp. 338-347
-
-
Trzonkowski, P.1
Zilvetti, M.2
Chapman, S.3
-
40
-
-
77949908711
-
+ CD8 T cells with suppressive potential in colorectal mucosa following a pathogenic simian immunodeficiency virus infection correlates with diminished antiviral T cell response and viral control
-
+ CD8 T cells with suppressive potential in colorectal mucosa following a pathogenic simian immunodeficiency virus infection correlates with diminished antiviral T cell response and viral control. J Immunol 2010; 184: 1690-1701.
-
(2010)
J Immunol
, vol.184
, pp. 1690-1701
-
-
Nigam, P.1
Velu, V.2
Kannanganat, S.3
-
42
-
-
55249113014
-
+ regulatory T cells from naive precursors by CD40-activated B cells
-
+ regulatory T cells from naive precursors by CD40-activated B cells. Blood 2008; 112: 2554-2562.
-
(2008)
Blood
, vol.112
, pp. 2554-2562
-
-
Tu, W.1
Lau, Y.L.2
Zheng, J.3
-
43
-
-
26044458206
-
Antigen-dependent suppression of alloresponses by Foxp3-induced regulatory T cells in transplantation
-
Albert MH, Liu Y, Anasetti C, Yu XZ., Antigen-dependent suppression of alloresponses by Foxp3-induced regulatory T cells in transplantation. Eur J Immunol 2005; 35: 2598-2607.
-
(2005)
Eur J Immunol
, vol.35
, pp. 2598-2607
-
-
Albert, M.H.1
Liu, Y.2
Anasetti, C.3
Yu, X.Z.4
|