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Volumn 8, Issue 2, 2008, Pages 338-347

Homeostatic repopulation by CD28-CD8+ T cells in alemtuzumab-depleted kidney transplant recipients treated with reduced immunosuppression

Author keywords

Alemtuzumab; CAMPATH 1H; Human; Memory; T cells; Tolerance suppression anergy; Transplantation

Indexed keywords

ALEMTUZUMAB; CD28 ANTIGEN; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; TACROLIMUS;

EID: 38149086827     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2007.02078.x     Document Type: Article
Times cited : (107)

References (29)
  • 1
    • 11144355749 scopus 로고    scopus 로고
    • Homeostatic proliferation is a barrier to transplantation tolerance
    • Wu Z, Bensinger SJ, Zhang J, Chen C et al. Homeostatic proliferation is a barrier to transplantation tolerance. Nat Med 2004 10 : 87 92.
    • (2004) Nat Med , vol.10 , pp. 87-92
    • Wu, Z.1    Bensinger, S.J.2    Zhang, J.3    Chen, C.4
  • 2
    • 20044380331 scopus 로고    scopus 로고
    • Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion
    • Pearl JP, Parris J, Hale DA et al. Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion. Am J Transplant 2005 5 : 465 474.
    • (2005) Am J Transplant , vol.5 , pp. 465-474
    • Pearl, J.P.1    Parris, J.2    Hale, D.A.3
  • 3
    • 33751529566 scopus 로고    scopus 로고
    • Recipient memory-like lymphocytes remain unresponsive to graft antigens after CAMPATH-1H induction with reduced maintenance immunosuppression
    • Trzonkowski P, Zilvetti M, Friend P, Wood KJ. Recipient memory-like lymphocytes remain unresponsive to graft antigens after CAMPATH-1H induction with reduced maintenance immunosuppression. Transplantation 2006 82 : 1342 1351.
    • (2006) Transplantation , vol.82 , pp. 1342-1351
    • Trzonkowski, P.1    Zilvetti, M.2    Friend, P.3    Wood, K.J.4
  • 4
    • 33645795235 scopus 로고    scopus 로고
    • Accelerated memory cell homeostasis during T cell depletion and approaches to overcome it
    • Neujahr DC, Chen C, Huang X et al. Accelerated memory cell homeostasis during T cell depletion and approaches to overcome it. J Immunol 2006 176 : 4632 4639.
    • (2006) J Immunol , vol.176 , pp. 4632-4639
    • Neujahr, D.C.1    Chen, C.2    Huang, X.3
  • 5
    • 0033610681 scopus 로고    scopus 로고
    • Campath IH allows low-dose cyclosporine monotherapy in 31 cadaveric renal allograft recipients
    • Calne R, Moffatt SD, Friend PJ et al. Campath IH allows low-dose cyclosporine monotherapy in 31 cadaveric renal allograft recipients. Transplantation 1999 68 : 1613 1616.
    • (1999) Transplantation , vol.68 , pp. 1613-1616
    • Calne, R.1    Moffatt, S.D.2    Friend, P.J.3
  • 6
    • 0038638396 scopus 로고    scopus 로고
    • Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (CAMPATH-1H)
    • Kirk AD, Hale DA, Mannon RB et al. Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (CAMPATH-1H). Transplantation 2003 76 : 120 129.
    • (2003) Transplantation , vol.76 , pp. 120-129
    • Kirk, A.D.1    Hale, D.A.2    Mannon, R.B.3
  • 7
    • 27744481221 scopus 로고    scopus 로고
    • Results from a human renal allograft tolerance trial evaluating T-cell depletion with alemtuzumab combined with deoxyspergualin
    • Kirk AD, Mannon RB, Kleiner DE et al. Results from a human renal allograft tolerance trial evaluating T-cell depletion with alemtuzumab combined with deoxyspergualin. Transplantation 2005 80 : 1051 1059.
    • (2005) Transplantation , vol.80 , pp. 1051-1059
    • Kirk, A.D.1    Mannon, R.B.2    Kleiner, D.E.3
  • 8
    • 33644827088 scopus 로고    scopus 로고
    • Development of tolerogenic strategies in the clinic
    • Knechtle SJ. Development of tolerogenic strategies in the clinic. Philos Trans R Soc Lond B Biol Sci 2005 360 : 1739 1746.
    • (2005) Philos Trans R Soc Lond B Biol Sci , vol.360 , pp. 1739-1746
    • Knechtle, S.J.1
  • 9
    • 20144389244 scopus 로고    scopus 로고
    • Kidney transplantation under minimal immunosuppression after pretransplant lymphoid depletion with Thymoglobulin or Campath
    • Shapiro R, Basu A, Tan H et al. Kidney transplantation under minimal immunosuppression after pretransplant lymphoid depletion with Thymoglobulin or Campath. J AmColl Surg 2005 200 : 505 515.
    • (2005) J AmColl Surg , vol.200 , pp. 505-515
    • Shapiro, R.1    Basu, A.2    Tan, H.3
  • 10
    • 20544458513 scopus 로고    scopus 로고
    • Alemtuzumab (CAMPATH 1H) induction therapy in cadaveric kidney transplantation - Efficacy and safety at five years
    • Watson CJ, Bradley J, Friend PJ et al. Alemtuzumab (CAMPATH 1H) induction therapy in cadaveric kidney transplantation - efficacy and safety at five years. Am J Transplant 2005 5 : 1347 1353.
    • (2005) Am J Transplant , vol.5 , pp. 1347-1353
    • Watson, C.J.1    Bradley, J.2    Friend, P.J.3
  • 11
    • 33644833287 scopus 로고    scopus 로고
    • Alemtuzumab induction and sirolimus plus mycophenolate mofetil maintenance for CNI and steroid-free kidney transplant immunosuppression
    • Flechner SM, Friend PJ, Brockmann J et al. Alemtuzumab induction and sirolimus plus mycophenolate mofetil maintenance for CNI and steroid-free kidney transplant immunosuppression. Am J Transplant 2005 5 : 3009 3014.
    • (2005) Am J Transplant , vol.5 , pp. 3009-3014
    • Flechner, S.M.1    Friend, P.J.2    Brockmann, J.3
  • 12
    • 33751522625 scopus 로고    scopus 로고
    • + memory T-cells in vitro with immunosuppressants
    • + memory T-cells in vitro with immunosuppressants. Transplantation 2006 82 : 1352 1361.
    • (2006) Transplantation , vol.82 , pp. 1352-1361
    • Jones, D.L.1    Sacks, S.H.2    Wong, W.3
  • 13
    • 27944439639 scopus 로고    scopus 로고
    • Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis
    • Cox AL, Thompson SA, Jones JL et al. Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis. Eur J Immunol 2005 35 : 3332 3342.
    • (2005) Eur J Immunol , vol.35 , pp. 3332-3342
    • Cox, A.L.1    Thompson, S.A.2    Jones, J.L.3
  • 14
    • 32844458509 scopus 로고    scopus 로고
    • + lymphocyte populations in long-term drug-free tolerance and chronic rejection in human kidney graft recipients
    • + lymphocyte populations in long-term drug-free tolerance and chronic rejection in human kidney graft recipients. J Am Soc Nephrol 2006 17 : 294 304.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 294-304
    • Baeten, D.1    Louis, S.2    Braud, C.3
  • 15
    • 4544349290 scopus 로고    scopus 로고
    • Will telomere erosion lead to a loss of T-cell memory?
    • Akbar AN, Beverley PC, Salmon M. Will telomere erosion lead to a loss of T-cell memory? Nat Rev Immunol 2004 4 : 737 743.
    • (2004) Nat Rev Immunol , vol.4 , pp. 737-743
    • Akbar, A.N.1    Beverley, P.C.2    Salmon, M.3
  • 16
    • 0028806679 scopus 로고
    • Long-term culture of monoclonal human T lymphocytes: Models for immunosenescence?
    • Adibzadeh M, Pohla H, Rehbein A, Pawelec G. Long-term culture of monoclonal human T lymphocytes: Models for immunosenescence? Mech Ageing Dev 1995 83 : 171 183.
    • (1995) Mech Ageing Dev , vol.83 , pp. 171-183
    • Adibzadeh, M.1    Pohla, H.2    Rehbein, A.3    Pawelec, G.4
  • 17
    • 0028177371 scopus 로고
    • Long-term in vitro growth of human T cell clones: Can postmitotic 'senescent' cell populations be defined?
    • Grubeck-Loebenstein B, Lechner H, Trieb K. Long-term in vitro growth of human T cell clones: Can postmitotic 'senescent' cell populations be defined? Int Arch Allergy Immunol 1994 104 : 232 239.
    • (1994) Int Arch Allergy Immunol , vol.104 , pp. 232-239
    • Grubeck-Loebenstein, B.1    Lechner, H.2    Trieb, K.3
  • 18
    • 0031960827 scopus 로고    scopus 로고
    • Replicative senescence in the immune system: Impact of the Hayflick limit on T cell function in the elderly. Human genetics 98: Ageing and senescence
    • Effros RB. Replicative senescence in the immune system: Impact of the Hayflick limit on T cell function in the elderly. Human genetics 98: Ageing and senescence. Am J Hum Genet 1998 62 : 1 5.
    • (1998) Am J Hum Genet , vol.62 , pp. 1-5
    • Effros, R.B.1
  • 19
    • 32044433093 scopus 로고    scopus 로고
    • Longitudinal studies of clonally expanded CD8 T-cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T-cells in the very elderly
    • Hadrup SR, Strindhall J, Kollgaard T et al. Longitudinal studies of clonally expanded CD8 T-cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T-cells in the very elderly. J Immunol 2006 176 : 2645 2653.
    • (2006) J Immunol , vol.176 , pp. 2645-2653
    • Hadrup, S.R.1    Strindhall, J.2    Kollgaard, T.3
  • 20
    • 0242317690 scopus 로고    scopus 로고
    • Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination - An impact of immunosenescence
    • Trzonkowski P, Mysliwska J, Szmit E et al. Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination - an impact of immunosenescence. Vaccine 2003 21 : 3826 3836.
    • (2003) Vaccine , vol.21 , pp. 3826-3836
    • Trzonkowski, P.1    Mysliwska, J.2    Szmit, E.3
  • 21
    • 0033975581 scopus 로고    scopus 로고
    • Human immunosenescence: The prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space
    • Franceschi C, Bonafe M, Valensin S. Human immunosenescence: The prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space. Vaccine 2000 18 : 1717 1720.
    • (2000) Vaccine , vol.18 , pp. 1717-1720
    • Franceschi, C.1    Bonafe, M.2    Valensin, S.3
  • 23
    • 8944258925 scopus 로고    scopus 로고
    • + cell subset in HIV disease implicate replicative senescence in HIV pathogenesis
    • + cell subset in HIV disease implicate replicative senescence in HIV pathogenesis. AIDS 1996 10 : F17 F22.
    • (1996) AIDS , vol.10
    • Effros, R.B.1    Allsopp, R.2    Chiu, C.P.3
  • 24
    • 0035348175 scopus 로고    scopus 로고
    • + T cell differentiation: Initial antigen encounter triggers a developmental program in naive cells
    • + T cell differentiation: Initial antigen encounter triggers a developmental program in naive cells. Nat Immunol 2001 2 : 415 422.
    • (2001) Nat Immunol , vol.2 , pp. 415-422
    • Kaech, S.M.1    Ahmed, R.2
  • 26
    • 10344249383 scopus 로고    scopus 로고
    • Molecular characterization of allospecific T suppressor and tolerogenic dendritic cells: Review
    • Suciu-Foca N, Manavalan JS, Scotto L et al. Molecular characterization of allospecific T suppressor and tolerogenic dendritic cells: Review. Int Immunopharmacol 2005 5 : 7 11.
    • (2005) Int Immunopharmacol , vol.5 , pp. 7-11
    • Suciu-Foca, N.1    Manavalan, J.S.2    Scotto, L.3
  • 28
    • 23944434883 scopus 로고    scopus 로고
    • A randomized trial of three renal transplant induction antibodies: Early comparison of tacrolimus, mycophenolate mofetil, and steroid dosing, and newer immune-monitoring
    • Ciancio G, Burke GW, Gaynor JJ et al. A randomized trial of three renal transplant induction antibodies: Early comparison of tacrolimus, mycophenolate mofetil, and steroid dosing, and newer immune-monitoring. Transplantation 2005 80 : 457 465.
    • (2005) Transplantation , vol.80 , pp. 457-465
    • Ciancio, G.1    Burke, G.W.2    Gaynor, J.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.