CD103 is a marker for alloantigen-induced regulatory CD8+ T cells

Journal of Immunology

Volumn 177, Issue 5, 2006, Pages 2775-2783

  Uss, Elena ^a,c   Rowshani, Ajda T ^a   Hooibrink, Berend ^a   Lardy, Neubury M ^b   Van Lier, René A W ^a   Ten Berge, Ineke J M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b HLA Diagnostics Laboratory   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; ALPHAEBETA7 INTEGRIN; CD103 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; INTEGRIN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; MONOCLONAL ANTIBODY; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UVOMORULIN;

ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CONTACT; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; HUMAN; HUMAN CELL; IMMUNOREGULATION; IMMUNOSTIMULATION; IN VITRO STUDY; INTESTINE; LUNG; LYMPHOCYTIC INFILTRATION; NORMAL HUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 33747789077     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.5.2775     Document Type: Article

References (51)

1. Chen, C., W. H. Lee, P. Yun, P. Snow, and C. P. Liu. 2003. Induction of autoantigen-specific Th2 and Tr1 regulatory T cells and modulation of autoimmune diabetes. J. Immunol. 171: 733-744.
2. Akdis, M., J. Verhagen, A. Taylor, F. Karamloo, C. Karagiannidis, R. Crameri, S. Thunberg, G. Deniz, R. Valenta, H. Fiebig, et al. 2004. Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J. Exp. Med. 199: 1567-1575.
3. Graca, L., A. Le Moine, S. P. Cobbold, and H. Waldmann. 2003. Dominant transplantation tolerance. Curr. Opin. Immunol. 15: 499-506.
4. Mills, K. H. 2004. Regulatory T cells: friend or foe in immunity to infection? Nat. Rev. Immunol. 4: 841-855.
5. Sakaguchi, S., N. Sakaguchi, M. Asano, M. Itoh, and M. Toda. 1995. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155: 1151-1164.
6. Vigouroux, S., E. Yvon, E. Biagi, and M. K. Brenner. 2004. Antigen-induced regulatory T cells. Blood 104: 26-33.
7. + regulatory T cells. Nat. Immunol. 4: 330-336.
8. Chen, Y., V. K. Kuchroo, J. Inobe, D. A. Hafler, and H. L. Weiner. 1994. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265: 1237-1240.
9. + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389: 737-742.
10. McGuirk, P., C. McCann, and K. H. Mills. 2002. Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis. J. Exp. Med. 195: 221-231.
11. + Tc1 and Tc2 populations in graft-versus-leukemia effect and graft-versus-host disease. J. Immunol. 157: 4811-4821.
12. Martin, P. J. 1993. Donor CD8 cells prevent allogeneic marrow graft rejection in mice: potential implications for marrow transplantation in humans. J. Exp. Med. 178: 703-712.
13. Gilliet, M., and Y. J. Liu. 2002. Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells. J. Exp. Med. 195: 695-704.
14. + suppressor T cells. J. Clin. Invest. 114: 1218-1221.
15. - T cells in an autoimmune disease model. J. Clin. Invest. 112: 1037-1048.
16. S cells: the crucial role of inhibitory receptors ILT3 and ILT4. Nat. Immunol. 3: 237-243.
17. 1-integrin crosslinking and TGF-β. Am. J. Respir. Cell Mol. Biol. 15: 600-610.
18. 7-containing integrin defined by HML-1 monoclonal antibody. Eur. J. Immunol. 22: 2887-2892.
19. + T lymphocytes. J. Invest. Dermatol. 117: 569-575.
20. 7). Eur. J. Immunol. 25: 852-856.
21. 7 integrin. Nature 372: 190-193.
22. + cytolytic T lymphocytes. Transplantation 67: 1418-1425.
23. + T cells. J. Exp. Med. 196: 877-886.
24. Hori, S., T. Nomura, and S. Sakaguchi. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science 299: 1057-1061.
25. + regulatory T cells controls wasting disease, IL-10 secretion and T cell homeostasis. Eur. J. Immunol. 33: 2419-2428.
26. - regulatory T cells. Proc. Natl. Acad. Sci. USA 99: 13031-13036.
27. He, X., C. A. Janeway, Jr., M. Levine, E. Robinson, P. Preston-Hurlburt, C. Viret, and K. Bottomly. 2002. Dual receptor T cells extend the immune repertoire for foreign antigens. Nat. Immunol. 3: 127-134.
28. Schelonka, R. L., F. M. Raaphorst, D. Infante, E. Kraig, J. M. Teale, and A. J. Infante. 1998. T cell receptor repertoire diversity and clonal expansion in human neonates. Pediatr. Res. 43: 396-402.
29. Maslanka, K., T. Piatek, J. Gorski, M. Yassai, and J. Gorski. 1995. Molecular analysis of T cell repertoires: spectratypes generated by multiplex polymerase chain reaction and evaluated by radioactivity or fluorescence. Hum. Immunol. 44: 28-34.
30. Zeijlemaker, W. P., M. H. Van Oers, and V. P. Eijsvoogel. 1976. Human lymphocyte subpopulations involved in MLC and CML. Scand. J. Immunol. (Suppl. 5): 143-156.
31. + CTL. J. Immunol. 159: 3748-3756.
32. + T cells in vitro. Transplantation 78: 815-824.
33. Wever, P. C., J. G. Boonstra, J. C. Laterveer, C. E. Hack, F. J. van der Woude, M. R. Daha, and I. J. Berge. 1998. Mechanisms of lymphocyte-mediated cytotoxicity in acute renal allograft rejection. Transplantation 66: 259-264.
34. Rowshani, A. T., S. Florquin, F. Bemelman, J. A. Kummer, C. E. Hack, and I. J. ten Berge. 2004. Hyperexpression of the granzyme B inhibitor PI-9 in human renal allografts: a potential mechanism for stable renal function in patients with subclinical rejection. Kidney Int. 66: 1417-1422.
35. Schieferdecker, H. L., R. Ullrich, A. N. Weiss-Breckwoldt, R. Schwarting, H. Stein, E. O. Riecken, and M. Zeitz. 1990. The HML-1 antigen of intestinal lymphocytes is an activation antigen. J. Immunol. 144: 2541-2549.
36. 7 (CD103) expression identifies a highly active, tonsil-resident effector-memory CTL population. J. Immunol. 175: 4355-4362.
37. Myers, L., M. Croft, B. S. Kwon, R. S. Mittler, and A. T. Vella. 2005. Peptide-specific CD8 T regulatory cells use IFN-γ to elaborate TGF-β-based suppression. J. Immunol. 174: 7625-7632.
38. + effectors in promoting tubular injury following allogeneic renal transplantation. J. Immunol. 175: 2868-2879.
39. 7 integrin) in the infiltrates of acute rejection in liver and kidney transplantation. Transplantation 70: 227-229.
40. +CTL accumulate within the graft epithelium during clinical renal allograft rejection. Transplantation 72: 1548-1555.
41. Waaga, A. M., M. Gasser, I. Laskowski, and N. L. Tilney. 2000. Mechanisms of chronic rejection. Curr. Opin. Immunol. 12: 517-521.
42. + T cells responding to renal allografts. J. Immunol. 172: 214-221.
43. + T cells in the psoriatic epidermis: regulation by interleukins 4 and 12 and transforming growth factor-β. Br. J. Dermatol. 147: 1118-1126.
44. + T cells: 1L-4 and IFN-γ have opposing effects, while TGF-β positively regulates its own production. J. Immunol. 160: 5719-5728.
45. + CTLs by TCR Vβ-derived peptides bound to HLA-E. J. Immunol. 167: 3800-3808.
46. Goronzy, J. J., C. Xie, W. Hu, S. K. Lundy, and C. M. Weyand. 1993. Restrictions in the repertoire of allospecific T cells: contribution of the α-helical sequence polymorphism of HLA-DR molecules. J. Immunol. 151: 825-836.
47. Gilliet, M., and Y. J. Liu. 2002. Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells. J. Exp. Med. 195: 695-704.
48. Malipiero, U., K. Frei, K. S. Spanaus, C. Agresti, H. Lassmann, M. Hahne, J. Tschopp, H. P. Eugster, and A. Fontana. 1997. Myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis is chronic/relapsing in perform knockout mice, but monophasic in Fas- and Fas ligand-deficient lpr and gld mice. Eur. J. Immunol. 27: 3151-3160.
49. Grossman, W. J., J. W. Verbsky, B. L. Tollefsen, C. Kemper, J. P. Atkinson, and T. J. Ley. 2004. Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells. Blood 104: 2840-2848.
50. Grossman, W. J., J. W. Verbsky, W. Barchet, M. Colonna, J. P. Atkinson, and T. J. Ley. 2004. Human T regulatory cells can use the perform pathway to cause autologous target cell death. Immunity 21: 589-601.
51. + regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. J. Immunol. 174: 1783-1786.