Atherosclerotic lesion formation and triglyceride storage in obese apolipoprotein AI-deficient mice

Journal of Nutritional Biochemistry

Volumn 19, Issue 10, 2008, Pages 664-673

  Plummer, Michelle R ^a   Hasty, Alyssa H ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adipose tissue; High density lipoprotein; Lipid partitioning; Obesity; Reverse cholesterol transport; Scavenger receptor BI

Indexed keywords

APOLIPOPROTEIN A1; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; SCAVENGER RECEPTOR BI;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; BUTTER; C57BL 6 MOUSE; CONTROLLED STUDY; DIET RESTRICTION; KNOCKOUT MOUSE; LIPID STORAGE; LIVER CLEARANCE; LIVER WEIGHT; MOUSE; NONHUMAN; WHITE ADIPOSE TISSUE;

ANIMALS; APOLIPOPROTEIN A-I; ATHEROSCLEROSIS; BLOTTING, WESTERN; LIPOLYSIS; MICE; MICE, INBRED C57BL; OBESITY; ORGAN SIZE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRIGLYCERIDES;

MUS;

EID: 50949117507     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2007.08.009     Document Type: Article

References (19)

1. Kuczmarski R.J., Flegal K.M., Campbell S.M., and Johnson C.L. Increasing prevalence of overweight among US adults. The National Health and Nutrition Examination Surveys, 1960 to 1991. JAMA 272 (1994) 205-211
2. Isomaa B., Almgren P., Tuomi T., Forsen B., Lahti K., Nissen M., et al. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care 24 (2001) 683-689
3. Nishina P.M., Lowe S., Wang J., and Paigen B. Characterization of plasma lipids in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow. Metabolism 43 (1994) 549-553
4. Silver D.L., Jiang X.C., and Tall A.R. Increased high density lipoprotein (HDL), defective hepatic catabolism of ApoA-I and ApoA-II, and decreased ApoA-I mRNA in ob/ob mice. Possible role of leptin in stimulation of HDL turnover. J Biol Chem 274 (1999) 4140-4146
5. Silver D.L., Wang N., and Tall A.R. Defective HDL particle uptake in ob/ob hepatocytes causes decreased recycling, degradation, and selective lipid uptake. J Clin Invest 105 (2000) 151-159
6. Gruen M.L., Plummer M.R., Zhang W., Posey K.A., Linton M.F., Fazio S., et al. Persistence of high density lipoprotein particles in obese mice lacking apolipoprotein A-I. J Lipid Res 46 (2005) 2007-2014
7. Paigen B., Morrow A., Holmes P.A., Mitchell D., and Williams R.A. Quantitative assessment of atherosclerotic lesions in mice. Atherosclerosis 68 (1987) 231-240
8. Folch J., Lees M., and Sloane Stanley G.H. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226 (1957) 497-509
9. Saraswathi V., and Hasty A.H. The role of lipolysis in mediating the proinflammatory effects of very low density lipoproteins in mouse peritoneal macrophages. J Lipid Res 47 (2006) 1406-1415
10. Li H., Reddick R.L., and Maeda N. Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice. Arterioscler Thromb 13 (1993) 1814-1821
11. Plump A.S., Azrolan N., Odaka H., Wu L., Jiang X., Tall A., et al. ApoA-I knockout mice: characterization of HDL metabolism in homozygotes and identification of a post-RNA mechanism of apoA-I up-regulation in heterozygotes. J Lipid Res 38 (1997) 1033-1047
12. Nishina P.M., Naggert J.K., Verstuyft J., and Paigen B. Atherosclerosis in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow. Metabolism 43 (1994) 554-558
13. Yancey P.G., de la Llera-Moya M., Swarnakar S., Monzo P., Klein S.M., Connelly M.A., et al. High density lipoprotein phospholipid composition is a major determinant of the bi-directional flux and net movement of cellular free cholesterol mediated by scavenger receptor BI. J Biol Chem 275 (2000) 36596-36604
14. de La Llera-Moya M., Connelly M.A., Drazul D., Klein S.M., Favari E., Yancey P.G., et al. Scavenger receptor Class B Type I affects cholesterol homeostasis by magnifying cholesterol flux between cells and HDL. J Lipid Res 42 (2001) 1969-1978
15. Trigatti B., Rigotti A., and Krieger M. The role of the high-density lipoprotein receptor SR-BI in cholesterol metabolism. Curr Opin Lipidol 11 (2000) 123-131
16. Vainio S., and Ikonen E. Macrophage cholesterol transport: a critical player in foam cell formation. Ann Med 35 (2003) 146-155
17. Yvan-Charvet L., Bobard A., Bossard P., Massiera F., Rousset X., Ailhaud G., et al. In vivo evidence for a role of adipose tissue SR-BI in the nutritional and hormonal regulation of adiposity and cholesterol homeostasis. Arterioscler Thromb Vasc Biol 27 (2007) 1340-1345
18. Zhao S.P., Wu Z.H., Hong S.C., Ye H.J., and Wu J. Effect of atorvastatin on SR-BI expression and HDL-induced cholesterol efflux in adipocytes of hypercholesterolemic rabbits. Clin Chim Acta 365 (2006) 119-124
19. Dugail I., Le Lay S., Varret M., Le Liepvre X., Dagher G., and Ferre P. New insights into how adipocytes sense their triglyceride stores. Is cholesterol a signal?. Horm Metab Res 35 (2003) 204-210