메뉴 건너뛰기




Volumn , Issue , 2012, Pages 493-524

Animal models of stroke for preclinical drug development: A comparative study of flavonols for cytoprotection

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84894566150     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4419-9530-8_25     Document Type: Chapter
Times cited : (3)

References (128)
  • 1
    • 4644310847 scopus 로고    scopus 로고
    • Behavioral and neuroplastic effects of focal endothelin-1 induced sensorimotor cortex lesions
    • Adkins DL, Voorhies AC, Jones TA. Behavioral and neuroplastic effects of focal endothelin-1 induced sensorimotor cortex lesions. Neuroscience. 2004;128:473-86.
    • (2004) Neuroscience , vol.128 , pp. 473-486
    • Adkins, D.L.1    Voorhies, A.C.2    Jones, T.A.3
  • 2
    • 0038364015 scopus 로고    scopus 로고
    • Microsurgical intraluminal middle cerebral artery occlusion model in rodents
    • Ardehali MR, Rondouin G. Microsurgical intraluminal middle cerebral artery occlusion model in rodents. Acta Neurol Scand. 2003;107:267-75.
    • (2003) Acta Neurol Scand , vol.107 , pp. 267-275
    • Ardehali, M.R.1    Rondouin, G.2
  • 3
    • 3042635436 scopus 로고    scopus 로고
    • Temperature-regulated model of focal ischemia in the mouse: A study with histopathological and behavioral outcomes
    • Barber PA, Hoyte L, Colbourne F, Buchan AM. Temperature-regulated model of focal ischemia in the mouse: a study with histopathological and behavioral outcomes. Stroke. 2004;35:1720-5.
    • (2004) Stroke , vol.35 , pp. 1720-1725
    • Barber, P.A.1    Hoyte, L.2    Colbourne, F.3    Buchan, A.M.4
  • 4
    • 0035879070 scopus 로고    scopus 로고
    • Enriched rehabilitative training promotes improved forelimb motor function and enhanced dendritic growth after focal ischemic injury
    • Biernaskie J, Corbett D. Enriched rehabilitative training promotes improved forelimb motor function and enhanced dendritic growth after focal ischemic injury. J Neurosci. 2001;21:5272-80.
    • (2001) J Neurosci , vol.21 , pp. 5272-5280
    • Biernaskie, J.1    Corbett, D.2
  • 5
    • 0034794176 scopus 로고    scopus 로고
    • A serial MR study of cerebral blood flow changes and lesion development following endothelin-1-induced ischemia in rats
    • Biernaskie J, Corbett D, Peeling J, Wells J, Lei H. A serial MR study of cerebral blood flow changes and lesion development following endothelin-1-induced ischemia in rats. Magn Reson Med. 2001;46:827-30.
    • (2001) Magn Reson Med , vol.46 , pp. 827-830
    • Biernaskie, J.1    Corbett, D.2    Peeling, J.3    Wells, J.4    Lei, H.5
  • 6
    • 0034888863 scopus 로고    scopus 로고
    • Anesthetic choice of halothane versus propofol: Impact on experimental perioperative stroke
    • Bhardwaj A, Castro AFI, Alkayed NJ, Hurn PD, Kirsch JR. Anesthetic choice of halothane versus propofol: impact on experimental perioperative stroke. Stroke. 2001;32:1920-5.
    • (2001) Stroke , vol.32 , pp. 1920-1925
    • Bhardwaj, A.1    Castro, A.F.I.2    Alkayed, N.J.3    Hurn, P.D.4    Kirsch, J.R.5
  • 7
    • 3242657223 scopus 로고    scopus 로고
    • Acute stroke therapy: Combination drugs and multifunctional neuroprotectants
    • Callaway JK. Acute stroke therapy: combination drugs and multifunctional neuroprotectants. Curr Neuropharmacol. 2004;2:277-94.
    • (2004) Curr Neuropharmacol , vol.2 , pp. 277-294
    • Callaway, J.K.1
  • 8
    • 0032752067 scopus 로고    scopus 로고
    • Delayed treatment with AM-36, a novel neuroprotective agent, reduces neuronal damage after endothelin-1-induced middle cerebral artery occlusion in conscious rats
    • Callaway JK, Knight MJ, Watkins DJ, Beart PM, Jarrott B. Delayed treatment with AM-36, a novel neuroprotective agent, reduces neuronal damage after endothelin-1-induced middle cerebral artery occlusion in conscious rats. Stroke. 1999;30:2704-12.
    • (1999) Stroke , vol.30 , pp. 2704-2712
    • Callaway, J.K.1    Knight, M.J.2    Watkins, D.J.3    Beart, P.M.4    Jarrott, B.5
  • 10
    • 0033969547 scopus 로고    scopus 로고
    • Relaxation to flavones and flavonols in rat isolated thoracic aorta: Mechanism of action and structure-activity relationships
    • Chan EC, Pannangpetch P, Woodman OL. Relaxation to flavones and flavonols in rat isolated thoracic aorta: mechanism of action and structure-activity relationships. J Cardiovasc Pharmacol. 2000;35:326-33.
    • (2000) J Cardiovasc Pharmacol , vol.35 , pp. 326-333
    • Chan, E.C.1    Pannangpetch, P.2    Woodman, O.L.3
  • 11
    • 0345017122 scopus 로고    scopus 로고
    • 3',4'-Dihydroxyflavonol enhances nitric oxidebio-availability and improves vascular function after ischemia and reperfusion injury in the rat
    • Chan EC, Drummond GR, Woodman OL. 3',4'-Dihydroxyflavonol enhances nitric oxidebio-availability and improves vascular function after ischemia and reperfusion injury in the rat. J Cardiovasc Pharmacol. 2003;42:727-35.
    • (2003) J Cardiovasc Pharmacol , vol.42 , pp. 727-735
    • Chan, E.C.1    Drummond, G.R.2    Woodman, O.L.3
  • 12
    • 0035149749 scopus 로고    scopus 로고
    • Reactive oxygen radicals in signaling and damage in the ischemic brain
    • Chan PH. Reactive oxygen radicals in signaling and damage in the ischemic brain. J Cereb Blood Flow Metab. 2001;21:2-14.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 2-14
    • Chan, P.H.1
  • 13
    • 77956414625 scopus 로고    scopus 로고
    • Quercetin: A potential drug to reverse multidrug resistance
    • Chen C, Zhou J, Ji C. Quercetin: a potential drug to reverse multidrug resistance. Life Sci. 2010;87:333-8.
    • (2010) Life Sci , vol.87 , pp. 333-338
    • Chen, C.1    Zhou, J.2    Ji, C.3
  • 14
    • 34250167199 scopus 로고    scopus 로고
    • Rodent stroke induced by photochemical occlusion of proximal middle cerebral artery: Evolution monitored with MR imaging and histopathology
    • Chen F, Suzuki Y, Nagai N, Jin L, Yu J, Wang H, Marchal G, Ni Y. Rodent stroke induced by photochemical occlusion of proximal middle cerebral artery: evolution monitored with MR imaging and histopathology. Eur J Radiol. 2007;63:68-75.
    • (2007) Eur J Radiol , vol.63 , pp. 68-75
    • Chen, F.1    Suzuki, Y.2    Nagai, N.3    Jin, L.4    Yu, J.5    Wang, H.6    Marchal, G.7    Ni, Y.8
  • 15
    • 33746533375 scopus 로고    scopus 로고
    • Protective effect of quercetin, a natural flavonoid against neuronal damage after transient global cerebral ischemia
    • Cho JY, Kim IS, Jang YH, Kim AR, Lee SR. Protective effect of quercetin, a natural flavonoid against neuronal damage after transient global cerebral ischemia. Neurosci Lett. 2006;40:330-5.
    • (2006) Neurosci Lett , vol.40 , pp. 330-335
    • Cho, J.Y.1    Kim, I.S.2    Jang, Y.H.3    Kim, A.R.4    Lee, S.R.5
  • 16
    • 0036215525 scopus 로고    scopus 로고
    • Predicting outcome after acute and subacute stroke: Development and validation of new prognostic models
    • Counsell C, Dennis M, McDowall M, Warlow C. Predicting outcome after acute and subacute stroke: development and validation of new prognostic models. Stroke. 2002;33:1041-7.
    • (2002) Stroke , vol.33 , pp. 1041-1047
    • Counsell, C.1    Dennis, M.2    McDowall, M.3    Warlow, C.4
  • 17
    • 0034801462 scopus 로고    scopus 로고
    • Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury
    • Crack PJ, Taylor JM, Flentjar NJ, de Haan J, Hertzog P, Iannello RC, Kola I. Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury. J Neurochem. 2001;78:1389-99.
    • (2001) J Neurochem , vol.78 , pp. 1389-1399
    • Crack, P.J.1    Taylor, J.M.2    Flentjar, N.J.3    de Haan, J.4    Hertzog, P.5    Iannello, R.C.6    Kola, I.7
  • 20
    • 0035122243 scopus 로고    scopus 로고
    • Malondialdehyde, glutathione peroxidase and superoxide dismutase in peripheral blood erythrocytes of patients with acute cerebral ischemia
    • Demirkaya S, Topcuoglu MA, Aydin A, Ulas UH, Isimer AI, Vural O. Malondialdehyde, glutathione peroxidase and superoxide dismutase in peripheral blood erythrocytes of patients with acute cerebral ischemia. Eur J Neurol. 2001;8:43-51.
    • (2001) Eur J Neurol , vol.8 , pp. 43-51
    • Demirkaya, S.1    Topcuoglu, M.A.2    Aydin, A.3    Ulas, U.H.4    Isimer, A.I.5    Vural, O.6
  • 21
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: An integrated view
    • Dirnagl U, Iadecola C, Moskowitz MA. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci. 1999;22:391-7.
    • (1999) Trends Neurosci , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 22
    • 0042919306 scopus 로고    scopus 로고
    • External carotid artery territory ischemia impairs outcome in the endovascular filament model of middle cerebral artery occlusion in rats
    • Dittmar M, Spruss T, Schuierer G, Horn M. External carotid artery territory ischemia impairs outcome in the endovascular filament model of middle cerebral artery occlusion in rats. Stroke. 2003;34:2252-7.
    • (2003) Stroke , vol.34 , pp. 2252-2257
    • Dittmar, M.1    Spruss, T.2    Schuierer, G.3    Horn, M.4
  • 23
    • 53449095870 scopus 로고    scopus 로고
    • Breaking the 3 h barrier for treatment of acute ischaemic stroke
    • Donnan G, Davis S. Breaking the 3 h barrier for treatment of acute ischaemic stroke. Lancet Neurol. 2008;7:981-2.
    • (2008) Lancet Neurol , vol.7 , pp. 981-982
    • Donnan, G.1    Davis, S.2
  • 25
    • 0030781313 scopus 로고    scopus 로고
    • Protection against oxidative damage of erythrocyte membrane by the flavonoid quercetin and its relation to iron chelating activity
    • Ferrali M, Signorini C, Caciotti B, Sugherini L, Ciccoli L, Giachetti D, Comporti M. Protection against oxidative damage of erythrocyte membrane by the flavonoid quercetin and its relation to iron chelating activity. FEBS Lett. 1997;416:123-9.
    • (1997) FEBS Lett , vol.416 , pp. 123-129
    • Ferrali, M.1    Signorini, C.2    Caciotti, B.3    Sugherini, L.4    Ciccoli, L.5    Giachetti, D.6    Comporti, M.7
  • 27
    • 0037252395 scopus 로고    scopus 로고
    • Models of focal cerebral ischemia in the nonhuman primate
    • Fukuda S, del Zoppo GJ. Models of focal cerebral ischemia in the nonhuman primate. ILAR J. 2003;44:96-104.
    • (2003) ILAR J , vol.44 , pp. 96-104
    • Fukuda, S.1    del Zoppo, G.J.2
  • 30
    • 0030807617 scopus 로고    scopus 로고
    • Endothelin-1 induced lesions of the frontoparietal cortex of the rat. A possible model of focal cortical ischemia
    • Fuxe K, Bjelke B, Andbjer B, Grahn H, Rimondini R, Agnati LF. Endothelin-1 induced lesions of the frontoparietal cortex of the rat. A possible model of focal cortical ischemia. Neuroreport. 1997;8:2623-9.
    • (1997) Neuroreport , vol.8 , pp. 2623-2629
    • Fuxe, K.1    Bjelke, B.2    Andbjer, B.3    Grahn, H.4    Rimondini, R.5    Agnati, L.F.6
  • 31
    • 0028947743 scopus 로고
    • Neuronal necrosis after middle cerebral artery occlusion in Wistar rats progresses at different time intervals in the caudoputamen and the cortex
    • Garcia JH, Liu KF, Ho KL. Neuronal necrosis after middle cerebral artery occlusion in Wistar rats progresses at different time intervals in the caudoputamen and the cortex. Stroke. 1995;26:636-42.
    • (1995) Stroke , vol.26 , pp. 636-642
    • Garcia, J.H.1    Liu, K.F.2    Ho, K.L.3
  • 32
    • 0037472778 scopus 로고    scopus 로고
    • The macrosphere model: Evaluation of a new stroke model for permanent middle cerebral artery occlusion in rats
    • Gerriets T, Li F, Silva MD, Meng X, Brevard M, Sotak CH, Fisher M. The macrosphere model: evaluation of a new stroke model for permanent middle cerebral artery occlusion in rats. J Neurosci Methods. 2003;122:201-11.
    • (2003) J Neurosci Methods , vol.122 , pp. 201-211
    • Gerriets, T.1    Li, F.2    Silva, M.D.3    Meng, X.4    Brevard, M.5    Sotak, C.H.6    Fisher, M.7
  • 33
    • 0042418531 scopus 로고    scopus 로고
    • Neuroprotective effects of MK-801 in different rat stroke models for permanent middle cerebral artery occlusion: Adverse effects of hypothalamic damage and strategies for its avoidance
    • Gerriets T, Stolz E, Walberer M, Kaps M, Bachmann G, Fisher M. Neuroprotective effects of MK-801 in different rat stroke models for permanent middle cerebral artery occlusion: adverse effects of hypothalamic damage and strategies for its avoidance. Stroke. 2003;34:2234-9.
    • (2003) Stroke , vol.34 , pp. 2234-2239
    • Gerriets, T.1    Stolz, E.2    Walberer, M.3    Kaps, M.4    Bachmann, G.5    Fisher, M.6
  • 34
    • 1642366572 scopus 로고    scopus 로고
    • The effects of intracortical endothe-lin-1 injections on skilled forelimb use: Implications for modelling recovery of function after stroke
    • Gilmour G, Iversen SD, O'Neill MF, Bannerman DM. The effects of intracortical endothe-lin-1 injections on skilled forelimb use: implications for modelling recovery of function after stroke. Behav Brain Res. 2004;150:171-83.
    • (2004) Behav Brain Res , vol.150 , pp. 171-183
    • Gilmour, G.1    Iversen, S.D.2    O'Neill, M.F.3    Bannerman, D.M.4
  • 35
    • 29744458225 scopus 로고    scopus 로고
    • Quercetin protects C6 glial cells from oxidative stress induced by tertiary-butylhydroperoxide
    • Gitika B, Sai Ram M, Sharma SK, Ilavazhagan G, Banerjee PK. Quercetin protects C6 glial cells from oxidative stress induced by tertiary-butylhydroperoxide. Free Radic Res. 2006;40:95-102.
    • (2006) Free Radic Res , vol.40 , pp. 95-102
    • Gitika, B.1    Sai Ram, M.2    Sharma, S.K.3    Ilavazhagan, G.4    Banerjee, P.K.5
  • 36
    • 33745955359 scopus 로고    scopus 로고
    • Therapeutic strategies for the treatment of stroke
    • Green AR, Shuaib A. Therapeutic strategies for the treatment of stroke. Drug Discov Today. 2006;11:681-93.
    • (2006) Drug Discov Today , vol.11 , pp. 681-693
    • Green, A.R.1    Shuaib, A.2
  • 37
    • 33748426170 scopus 로고    scopus 로고
    • Injury to axons and oligodendrocytes following endothelin-1-induced middle cerebral artery occlusion in conscious rats
    • Gresle MM, Jarrott B, Jones NM, Callaway JK. Injury to axons and oligodendrocytes following endothelin-1-induced middle cerebral artery occlusion in conscious rats. Brain Res. 2006;1110:13-22.
    • (2006) Brain Res , vol.1110 , pp. 13-22
    • Gresle, M.M.1    Jarrott, B.2    Jones, N.M.3    Callaway, J.K.4
  • 38
    • 0033900321 scopus 로고    scopus 로고
    • Cortical neurogenesis in adult rats after reversible photothrombotic stroke
    • Gu W, Brannstrom T, Wester P. Cortical neurogenesis in adult rats after reversible photothrombotic stroke. J Cereb Blood Flow Metab. 2000;20:1166-73.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 1166-1173
    • Gu, W.1    Brannstrom, T.2    Wester, P.3
  • 39
    • 0034861099 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-A and -C protein up-regulation and early angiogenesis in a rat photothrombotic ring stroke model with spontaneous reperfusion
    • Gu W, Brannstrom T, Jiang W, Bergh A, Wester P. Vascular endothelial growth factor-A and -C protein up-regulation and early angiogenesis in a rat photothrombotic ring stroke model with spontaneous reperfusion. Acta Neuropathol. 2001;102:216-26.
    • (2001) Acta Neuropathol , vol.102 , pp. 216-226
    • Gu, W.1    Brannstrom, T.2    Jiang, W.3    Bergh, A.4    Wester, P.5
  • 40
    • 0031829004 scopus 로고    scopus 로고
    • Endothelin as a regulator of cardiovascular function in health and disease
    • Haynes WG, Webb DJ. Endothelin as a regulator of cardiovascular function in health and disease. J Hypertens. 1998;16:1081-98.
    • (1998) J Hypertens , vol.16 , pp. 1081-1098
    • Haynes, W.G.1    Webb, D.J.2
  • 41
  • 42
    • 3042706276 scopus 로고    scopus 로고
    • Lost in translation: Taking neuroprotection from animal models to clinical trials
    • Hoyte L, Kaur J, Buchan AM. Lost in translation: taking neuroprotection from animal models to clinical trials. Exp Neurol. 2004;188:200-4.
    • (2004) Exp Neurol , vol.188 , pp. 200-204
    • Hoyte, L.1    Kaur, J.2    Buchan, A.M.3
  • 43
    • 0035080062 scopus 로고    scopus 로고
    • Progressive and reproducible focal cortical ischemia with or without late spontaneous reperfusion generated by a ring-shaped, laser-driven photothrombotic lesion in rats
    • Hu X, Wester P, Brannstrom T, Watson BD, Gu W. Progressive and reproducible focal cortical ischemia with or without late spontaneous reperfusion generated by a ring-shaped, laser-driven photothrombotic lesion in rats. Brain Res Brain Res Protoc. 2001;7:76-85.
    • (2001) Brain Res Brain Res Protoc , vol.7 , pp. 76-85
    • Hu, X.1    Wester, P.2    Brannstrom, T.3    Watson, B.D.4    Gu, W.5
  • 44
    • 4544308331 scopus 로고    scopus 로고
    • Dynamic changes of the anti- and pro-apoptotic proteins Bcl-w, Bcl-2, and Bax with Smac/Diablo mitochondrial release after photothrombotic ring stroke in rats
    • Hu XL, Olsson T, Johansson IM, Brannstrom T, Wester P. Dynamic changes of the anti- and pro-apoptotic proteins Bcl-w, Bcl-2, and Bax with Smac/Diablo mitochondrial release after photothrombotic ring stroke in rats. Eur J Neurosci. 2004;20:1177-88.
    • (2004) Eur J Neurosci , vol.20 , pp. 1177-1188
    • Hu, X.L.1    Olsson, T.2    Johansson, I.M.3    Brannstrom, T.4    Wester, P.5
  • 46
    • 33745580593 scopus 로고    scopus 로고
    • Establishing a photothrombotic 'ring' stroke model in adult mice with late spontaneous reperfusion: Quantitative measurements of cerebral blood flow and cerebral protein synthesis
    • Jiang W, Gu W, Hossmann KA, Mies G, Wester P. Establishing a photothrombotic 'ring' stroke model in adult mice with late spontaneous reperfusion: quantitative measurements of cerebral blood flow and cerebral protein synthesis. J Cereb Blood Flow Metab. 2006;26:927-36.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 927-936
    • Jiang, W.1    Gu, W.2    Hossmann, K.A.3    Mies, G.4    Wester, P.5
  • 47
    • 77952513645 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: Role of inflammatory cells
    • Jin R, Yang G, Li G. Inflammatory mechanisms in ischemic stroke: role of inflammatory cells. J Leukocyte Biol. 2010;87:779-89.
    • (2010) J Leukocyte Biol , vol.87 , pp. 779-789
    • Jin, R.1    Yang, G.2    Li, G.3
  • 48
    • 0036791921 scopus 로고    scopus 로고
    • Differences in the extent of primary ischemic damage between middle cerebral artery coagulation and intraluminal occlusion models
    • Kanemitsu H, Nakagomi T, Tamura A, Tsuchiya T, Kono G, Sano K. Differences in the extent of primary ischemic damage between middle cerebral artery coagulation and intraluminal occlusion models. J Cereb Blood Flow Metab. 2002;22:1196-204.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 1196-1204
    • Kanemitsu, H.1    Nakagomi, T.2    Tamura, A.3    Tsuchiya, T.4    Kono, G.5    Sano, K.6
  • 49
    • 0036310780 scopus 로고    scopus 로고
    • Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent
    • Kapinya KJ, Löwl D, Fütterer C, Maurer M, Waschke KF, Isaev NK, Dirnagl U. Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent. Stroke. 2002;33:1889-98.
    • (2002) Stroke , vol.33 , pp. 1889-1898
    • Kapinya, K.J.1    Löwl, D.2    Fütterer, C.3    Maurer, M.4    Waschke, K.F.5    Isaev, N.K.6    Dirnagl, U.7
  • 50
    • 77958065233 scopus 로고    scopus 로고
    • Considerations for the use of anesthetics in neurotoxicity studies
    • Karmarkar SW, Bottum KM, Tischkau SA. Considerations for the use of anesthetics in neurotoxicity studies. Comp Med. 2010;60:256-62.
    • (2010) Comp Med , vol.60 , pp. 256-262
    • Karmarkar, S.W.1    Bottum, K.M.2    Tischkau, S.A.3
  • 52
    • 41149095178 scopus 로고    scopus 로고
    • Blocking of platelets or intrinsic coagulation pathway-driven thrombosis does not prevent cerebral infarctions induced by photothrombosis
    • Kleinschnitz C, Braeuninger S, Pham M, Austinat M, Nolte I, Renne T, Nieswandt B, Bendszus M, Stoll G. Blocking of platelets or intrinsic coagulation pathway-driven thrombosis does not prevent cerebral infarctions induced by photothrombosis. Stroke. 2008;39:1262-8.
    • (2008) Stroke , vol.39 , pp. 1262-1268
    • Kleinschnitz, C.1    Braeuninger, S.2    Pham, M.3    Austinat, M.4    Nolte, I.5    Renne, T.6    Nieswandt, B.7    Bendszus, M.8    Stoll, G.9
  • 53
    • 0002254106 scopus 로고
    • Experimental studies of brain edema, 1: A new experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area
    • Koizumi J, Yoshida Y, Nazakawa T, Ooneda G. Experimental studies of brain edema, 1: a new experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area. Jpn J Stroke. 1986;8:1-8.
    • (1986) Jpn J Stroke , vol.8 , pp. 1-8
    • Koizumi, J.1    Yoshida, Y.2    Nazakawa, T.3    Ooneda, G.4
  • 54
    • 0019986718 scopus 로고
    • An animal model of cerebral infarction. Homologous blood clot emboli in rats
    • Kudo M, Aoyama A, Ichimori S, Fukunaga N. An animal model of cerebral infarction. Homologous blood clot emboli in rats. Stroke. 1982;13:505-8.
    • (1982) Stroke , vol.13 , pp. 505-508
    • Kudo, M.1    Aoyama, A.2    Ichimori, S.3    Fukunaga, N.4
  • 56
    • 77953639695 scopus 로고    scopus 로고
    • Translational stroke research using a rabbit embolic stroke model: A correlative analysis hypothesis for novel therapy development
    • Lapchak PA. Translational stroke research using a rabbit embolic stroke model: a correlative analysis hypothesis for novel therapy development. Transl Stroke Res. 2010;1:96-107.
    • (2010) Transl Stroke Res , vol.1 , pp. 96-107
    • Lapchak, P.A.1
  • 57
    • 0141954290 scopus 로고    scopus 로고
    • Development of the nitrone-based spin trap agent NXY-059 to treat acute ischemic stroke
    • Lapchak PA, Araujo DM. Development of the nitrone-based spin trap agent NXY-059 to treat acute ischemic stroke. CNS Drug Rev. 2003;9:253-62.
    • (2003) CNS Drug Rev , vol.9 , pp. 253-262
    • Lapchak, P.A.1    Araujo, D.M.2
  • 58
    • 0036098259 scopus 로고    scopus 로고
    • Neuroprotective effects of the spin trap agent disodium-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) in a rabbit small clot embolic stroke model: Combination studies with the thrombolytic tissue plasminogen activator
    • Lapchak PA, Araujo DM, Song D, Wei J, Zivin JA. Neuroprotective effects of the spin trap agent disodium-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) in a rabbit small clot embolic stroke model: combination studies with the thrombolytic tissue plasminogen activator. Stroke. 2002;33:1411-5.
    • (2002) Stroke , vol.33 , pp. 1411-1415
    • Lapchak, P.A.1    Araujo, D.M.2    Song, D.3    Wei, J.4    Zivin, J.A.5
  • 59
    • 0347624526 scopus 로고    scopus 로고
    • Comparison of tenecteplase with alteplase on clinical rating scores following small clot embolic strokes in rabbits
    • Lapchak PA, Araujo DM, Zivin JA. Comparison of tenecteplase with alteplase on clinical rating scores following small clot embolic strokes in rabbits. Exp Neurol. 2004;185:154-9.
    • (2004) Exp Neurol , vol.185 , pp. 154-159
    • Lapchak, P.A.1    Araujo, D.M.2    Zivin, J.A.3
  • 60
    • 79959560081 scopus 로고    scopus 로고
    • Quercetin reduces the elevated matrix metalloproteinases-9 level and improves functional outcome after cerebral focal ischemia in rats
    • Lee JK, Kwak HJ, Piao MS, Jang JW, Kim SH, Kim HS. Quercetin reduces the elevated matrix metalloproteinases-9 level and improves functional outcome after cerebral focal ischemia in rats. Acta Neurochir (Wien). 2011;153:1321-9.
    • (2011) Acta Neurochir (Wien) , vol.153 , pp. 1321-1329
    • Lee, J.K.1    Kwak, H.J.2    Piao, M.S.3    Jang, J.W.4    Kim, S.H.5    Kim, H.S.6
  • 62
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • Longa EZ, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke. 1989;20:84-91.
    • (1989) Stroke , vol.20 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 63
    • 0027399173 scopus 로고
    • Endothelin-1-induced reductions in cerebral blood flow: Dose dependency, time course, and neuropathological consequences
    • Macrae IM, Robinson MJ, Graham DI, Reid JL, McCulloch J. Endothelin-1-induced reductions in cerebral blood flow: dose dependency, time course, and neuropathological consequences. J Cereb Blood Flow Metab. 1993;13:276-84.
    • (1993) J Cereb Blood Flow Metab , vol.13 , pp. 276-284
    • Macrae, I.M.1    Robinson, M.J.2    Graham, D.I.3    Reid, J.L.4    McCulloch, J.5
  • 64
    • 48149095229 scopus 로고    scopus 로고
    • The flavonoid fisetin promotes nerve cell survival from trophic factor withdrawal by enhancement of proteasome activity
    • Maher P. The flavonoid fisetin promotes nerve cell survival from trophic factor withdrawal by enhancement of proteasome activity. Arch Biochem Biophys. 2008;476:139-44.
    • (2008) Arch Biochem Biophys , vol.476 , pp. 139-144
    • Maher, P.1
  • 65
    • 71949125029 scopus 로고    scopus 로고
    • Modulation of multiple pathways involved in the maintenance of neuronal function during aging by fisetin
    • Maher P. Modulation of multiple pathways involved in the maintenance of neuronal function during aging by fisetin. Genes Nutr. 2009;4:297-307.
    • (2009) Genes Nutr , vol.4 , pp. 297-307
    • Maher, P.1
  • 66
    • 34548855340 scopus 로고    scopus 로고
    • A novel approach to screening for new neuroprotective compounds for the treatment of stroke
    • Maher P, Salgado KF, Zivin JA, Lapchak PA. A novel approach to screening for new neuroprotective compounds for the treatment of stroke. Brain Res. 2007;1173:117-25.
    • (2007) Brain Res , vol.1173 , pp. 117-125
    • Maher, P.1    Salgado, K.F.2    Zivin, J.A.3    Lapchak, P.A.4
  • 69
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
    • Middleton Jr E, Kandaswami C, Theoharides TC. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev. 2000;52:673-751.
    • (2000) Pharmacol Rev , vol.52 , pp. 673-751
    • Middleton, E.1    Kandaswami, C.2    Theoharides, T.C.3
  • 71
    • 0027405380 scopus 로고
    • Sustained decrease in brain regional blood flow after microsphere embolism in rats
    • Miyake K, Takeo S, Kaijihara H. Sustained decrease in brain regional blood flow after microsphere embolism in rats. Stroke. 1993;24:415-20.
    • (1993) Stroke , vol.24 , pp. 415-420
    • Miyake, K.1    Takeo, S.2    Kaijihara, H.3
  • 72
    • 0029143932 scopus 로고
    • Perfusion and diffusion-weighted MR imaging for in vivo evaluation of treatment with U74389G in a rat stroke model
    • Muller TB, Haraldseth O, Jones RA, Sebastiani G, Lindboe CF, Unsgard G, Oksendal AN. Perfusion and diffusion-weighted MR imaging for in vivo evaluation of treatment with U74389G in a rat stroke model. Stroke. 1995;26:1453-8.
    • (1995) Stroke , vol.26 , pp. 1453-1458
    • Muller, T.B.1    Haraldseth, O.2    Jones, R.A.3    Sebastiani, G.4    Lindboe, C.F.5    Unsgard, G.6    Oksendal, A.N.7
  • 73
    • 0042122367 scopus 로고    scopus 로고
    • Differences in clot preparation determine outcome of recombinant tissue plasminogen activator treatment in experimental thromboembolic stroke
    • Niessen F, Hilger T, Hoehn M, Hossmann KA. Differences in clot preparation determine outcome of recombinant tissue plasminogen activator treatment in experimental thromboembolic stroke. Stroke. 2003;34:2019-24.
    • (2003) Stroke , vol.34 , pp. 2019-2024
    • Niessen, F.1    Hilger, T.2    Hoehn, M.3    Hossmann, K.A.4
  • 74
    • 0027326241 scopus 로고
    • Endothelin-1 exacerbates focal cerebral ischemia without exerting neurotoxic action in vitro
    • Nikolov R, Rami A, Krieglstein J. Endothelin-1 exacerbates focal cerebral ischemia without exerting neurotoxic action in vitro. Eur J Pharmacol. 1993;248:205-8.
    • (1993) Eur J Pharmacol , vol.248 , pp. 205-208
    • Nikolov, R.1    Rami, A.2    Krieglstein, J.3
  • 77
    • 0023219197 scopus 로고
    • Leakiness of rat brain microvessels to fluorescent probes following craniotomy
    • Olesen SP. Leakiness of rat brain microvessels to fluorescent probes following craniotomy. Acta Physiol Scand. 1987;130:63-8.
    • (1987) Acta Physiol Scand , vol.130 , pp. 63-68
    • Olesen, S.P.1
  • 78
    • 43249123028 scopus 로고    scopus 로고
    • Rodent models of focal cerebral ischemia
    • O'Neill MJ, Clemens JA. Rodent models of focal cerebral ischemia. Curr Protoc Neurosci. 2001;9.6.1-9.6.32.
    • (2001) Curr Protoc Neurosci , pp. 9.6.1-9.6.32.
    • O'Neill, M.J.1    Clemens, J.A.2
  • 80
    • 79952986535 scopus 로고    scopus 로고
    • The role of ASIC1a in neuroprotection elicited by quercetin in focal cerebral ischemia
    • Pandey AK, Hazari PP, Patnaik R, Mishra AK. The role of ASIC1a in neuroprotection elicited by quercetin in focal cerebral ischemia. Brain Res. 2011;1383:289-99.
    • (2011) Brain Res , vol.1383 , pp. 289-299
    • Pandey, A.K.1    Hazari, P.P.2    Patnaik, R.3    Mishra, A.K.4
  • 81
    • 0033859612 scopus 로고    scopus 로고
    • Flavonoids as antioxidants
    • Pietta PG. Flavonoids as antioxidants. J Nat Prod. 2000;63:1035-42.
    • (2000) J Nat Prod , vol.63 , pp. 1035-1042
    • Pietta, P.G.1
  • 82
    • 77955081026 scopus 로고    scopus 로고
    • Targeting inflammatory pathways by flavonoids for prevention and treatment of cancer
    • Prasad S, Phromnoi K, Yadav VR, Chaturvedi MM, Aggarwal BB. Targeting inflammatory pathways by flavonoids for prevention and treatment of cancer. Planta Med. 2010;76:1044-63.
    • (2010) Planta Med , vol.76 , pp. 1044-1063
    • Prasad, S.1    Phromnoi, K.2    Yadav, V.R.3    Chaturvedi, M.M.4    Aggarwal, B.B.5
  • 83
    • 0042886941 scopus 로고    scopus 로고
    • Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation
    • Prass K, Meisel C, Hoflich C, Braun J, Halle E, WolfT, Ruscher K, Victorov IV, Priller J, Dirnagl U, Volk HD, Meisel A. Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation. J Exp Med. 2003;198:725-36.
    • (2003) J Exp Med , vol.198 , pp. 725-736
    • Prass, K.1    Meisel, C.2    Hoflich, C.3    Braun, J.4    Halle, E.5    Wolf, T.6    Ruscher, K.7    Victorov, I.V.8    Priller, J.9    Dirnagl, U.10    Volk, H.D.11    Meisel, A.12
  • 84
    • 0035004114 scopus 로고    scopus 로고
    • Flavonoid antioxidants
    • Rice-Evans C. Flavonoid antioxidants. Curr Med Chem. 2001;8:797-807.
    • (2001) Curr Med Chem , vol.8 , pp. 797-807
    • Rice-Evans, C.1
  • 85
    • 15844374508 scopus 로고    scopus 로고
    • Some aspects of the in vivo neuroprotective capacity of flavonoids: Bioavailability and structure-activity relationship
    • Rivera F, Urbanavicius J, Gervaz E, Morquio A, Dajas F. Some aspects of the in vivo neuroprotective capacity of flavonoids: bioavailability and structure-activity relationship. Neurotox Res. 2004;6:543-53.
    • (2004) Neurotox Res , vol.6 , pp. 543-553
    • Rivera, F.1    Urbanavicius, J.2    Gervaz, E.3    Morquio, A.4    Dajas, F.5
  • 86
    • 49849101939 scopus 로고    scopus 로고
    • Reduction of ischemic brain damage and increase of glutathione by a liposomal preparation of quercetin in permanent focal ischemia in rats
    • Rivera F, Costa G, Abin A, Urbanavicius J, Arruti C, Casanova G, Dajas F. Reduction of ischemic brain damage and increase of glutathione by a liposomal preparation of quercetin in permanent focal ischemia in rats. Neurotox Res. 2008;13:105-14.
    • (2008) Neurotox Res , vol.13 , pp. 105-114
    • Rivera, F.1    Costa, G.2    Abin, A.3    Urbanavicius, J.4    Arruti, C.5    Casanova, G.6    Dajas, F.7
  • 87
    • 0031040148 scopus 로고    scopus 로고
    • Neuropsychiatric consequences of stroke
    • Robinson RG. Neuropsychiatric consequences of stroke. Annu Rev Med. 1997;48:217-29.
    • (1997) Annu Rev Med , vol.48 , pp. 217-229
    • Robinson, R.G.1
  • 88
    • 0025027060 scopus 로고
    • Reduction of local cerebral blood flow to pathological levels by endothelin-1 applied to the middle cerebral artery in the rat
    • Robinson MJ, Macrae IM, Todd M, Reid JL, McCulloch J. Reduction of local cerebral blood flow to pathological levels by endothelin-1 applied to the middle cerebral artery in the rat. Neurosci Lett. 1990;118:269-72.
    • (1990) Neurosci Lett , vol.118 , pp. 269-272
    • Robinson, M.J.1    Macrae, I.M.2    Todd, M.3    Reid, J.L.4    McCulloch, J.5
  • 89
    • 41149090581 scopus 로고    scopus 로고
    • Using behaviour to predict stroke severity in conscious rats: Post-stroke treatment with 3',4'-dihydroxyflavonol improves recovery
    • Roulston CL, Callaway JK, Jarrott B, Woodman OL, Dusting GJ. Using behaviour to predict stroke severity in conscious rats: post-stroke treatment with 3',4'-dihydroxyflavonol improves recovery. Eur J Pharmacol. 2008;584:100-10.
    • (2008) Eur J Pharmacol , vol.584 , pp. 100-110
    • Roulston, C.L.1    Callaway, J.K.2    Jarrott, B.3    Woodman, O.L.4    Dusting, G.J.5
  • 91
    • 13844275969 scopus 로고    scopus 로고
    • Prospects for the future: The role of free radicals in the treatment of stroke
    • Schaller B. Prospects for the future: the role of free radicals in the treatment of stroke. Free Radic Biol Med. 2005;38:411-25.
    • (2005) Free Radic Biol Med , vol.38 , pp. 411-425
    • Schaller, B.1
  • 92
    • 0031665617 scopus 로고    scopus 로고
    • A critical reevaluation of the intraluminal thread model of focal cerebral ischemia: Evidence of inadvertent premature reperfusion and subarachnoid hemorrhage in rats by laser-doppler flowmetry
    • Schmid-Elsaesser R, Zausinger S, Hungerhuber E, Baethmann A, Reulen HJ. A critical reevaluation of the intraluminal thread model of focal cerebral ischemia: evidence of inadvertent premature reperfusion and subarachnoid hemorrhage in rats by laser-doppler flowmetry. Stroke. 1998;29:2162-70.
    • (1998) Stroke , vol.29 , pp. 2162-2170
    • Schmid-Elsaesser, R.1    Zausinger, S.2    Hungerhuber, E.3    Baethmann, A.4    Reulen, H.J.5
  • 95
    • 0027164675 scopus 로고
    • Perivascular microapplication of endothelin-1: A new model of focal cerebral ischaemia in rats
    • Sharkey J, Ritchie IM, Kelly PA. Perivascular microapplication of endothelin-1: a new model of focal cerebral ischaemia in rats. J Cereb Blood Flow Metab. 1993;13:865-71.
    • (1993) J Cereb Blood Flow Metab , vol.13 , pp. 865-871
    • Sharkey, J.1    Ritchie, I.M.2    Kelly, P.A.3
  • 96
    • 0027991602 scopus 로고
    • Endothelin-1 induced middle cerebral artery occlusion: Pathological consequences and neuroprotective effects of MK801
    • Sharkey J, Butcher SP, Kelly JS. Endothelin-1 induced middle cerebral artery occlusion: pathological consequences and neuroprotective effects of MK801. J Auton Nerv Syst. 1994;49 Suppl:S177-85.
    • (1994) J Auton Nerv Syst , vol.49 , pp. S177-S185
    • Sharkey, J.1    Butcher, S.P.2    Kelly, J.S.3
  • 97
    • 0029085707 scopus 로고
    • Characterisation of an experimental model of stroke produced by intracerebral microinjection of endothelin-1 adjacent to the rat middle cerebral artery
    • Sharkey J, Butcher SP. Characterisation of an experimental model of stroke produced by intracerebral microinjection of endothelin-1 adjacent to the rat middle cerebral artery. J Neurosci Methods. 1995;60:125-31.
    • (1995) J Neurosci Methods , vol.60 , pp. 125-131
    • Sharkey, J.1    Butcher, S.P.2
  • 98
    • 59849123367 scopus 로고    scopus 로고
    • Metabolism and pharmacokinetics of 3,3',4',7-tetrahydroxyflavone (fisetin), 5-hydroxyflavone, and 7-hydroxyflavone and antihemolysis effects of fisetin and its serum metabolites
    • Shia CS, Tsai SY, Kuo SC, Hou YC, Chao PD. Metabolism and pharmacokinetics of 3,3',4',7-tetrahydroxyflavone (fisetin), 5-hydroxyflavone, and 7-hydroxyflavone and antihemolysis effects of fisetin and its serum metabolites. J Agric Food Chem. 2009;57:83-9.
    • (2009) J Agric Food Chem , vol.57 , pp. 83-89
    • Shia, C.S.1    Tsai, S.Y.2    Kuo, S.C.3    Hou, Y.C.4    Chao, P.D.5
  • 99
    • 0032901807 scopus 로고    scopus 로고
    • Influence of the antioxidant quercetin in vivo on the level of nitric oxide determined by electron paramagnetic resonance in rat brain during global ischemia and reperfusion
    • Shutenko Z, Henry Y, Pinard E, Seylaz J, Potier P, Berthet F, Girard P, Sercombe R. Influence of the antioxidant quercetin in vivo on the level of nitric oxide determined by electron paramagnetic resonance in rat brain during global ischemia and reperfusion. Biochem Pharmacol. 1999;57:199-208.
    • (1999) Biochem Pharmacol , vol.57 , pp. 199-208
    • Shutenko, Z.1    Henry, Y.2    Pinard, E.3    Seylaz, J.4    Potier, P.5    Berthet, F.6    Girard, P.7    Sercombe, R.8
  • 101
    • 65649106234 scopus 로고    scopus 로고
    • A white matter stroke model in the mouse: Axonal damage, progenitor responses and MRI correlates
    • Sozmen EG, Kolekar A, Havton LA, Carmichael ST. A white matter stroke model in the mouse: axonal damage, progenitor responses and MRI correlates. J Neurosci Methods. 2009;180:261-72.
    • (2009) J Neurosci Methods , vol.180 , pp. 261-272
    • Sozmen, E.G.1    Kolekar, A.2    Havton, L.A.3    Carmichael, S.T.4
  • 102
    • 0020656735 scopus 로고
    • Acute NMR changes during MCA occlusion: A preliminary study in primates
    • Spetzler RF, Zabramski JM, Kaufman B, Yeung HN. Acute NMR changes during MCA occlusion: a preliminary study in primates. Stroke. 1983;14:185-91.
    • (1983) Stroke , vol.14 , pp. 185-191
    • Spetzler, R.F.1    Zabramski, J.M.2    Kaufman, B.3    Yeung, H.N.4
  • 104
    • 33747180092 scopus 로고    scopus 로고
    • Modification of the method of thread manufacture improves stroke induction rate and reduces mortality after thread-occlusion of the middle cerebral artery in young or aged rats
    • Spratt NJ, Fernandez J, Chen M, Rewell S, Cox S, van Raay L, Hogan L, Howells DW. Modification of the method of thread manufacture improves stroke induction rate and reduces mortality after thread-occlusion of the middle cerebral artery in young or aged rats. J Neurosci Methods. 2006;155:285-90.
    • (2006) J Neurosci Methods , vol.155 , pp. 285-290
    • Spratt, N.J.1    Fernandez, J.2    Chen, M.3    Rewell, S.4    Cox, S.5    van Raay, L.6    Hogan, L.7    Howells, D.W.8
  • 105
    • 47649114689 scopus 로고    scopus 로고
    • Filamentous middle cerebral artery occlusion causes ischemic damage to the retina in mice
    • Steele Jr EC, Guo Q, Namura S. Filamentous middle cerebral artery occlusion causes ischemic damage to the retina in mice. Stroke. 2008;39:2099-104.
    • (2008) Stroke , vol.39 , pp. 2099-2104
    • Steele, E.C.1    Guo, Q.2    Namura, S.3
  • 106
    • 0344065373 scopus 로고    scopus 로고
    • Recommendations for standards regarding preclinical neuroprotective and restorative drug development
    • Stroke Therapy Academic Industry Roundtable I (STAIR-I). Recommendations for standards regarding preclinical neuroprotective and restorative drug development. Stroke. 1999;30:2752-8.
    • (1999) Stroke , vol.30 , pp. 2752-2758
  • 107
    • 0034943173 scopus 로고    scopus 로고
    • Recommendations for clinical trial evaluation of acute stroke therapies
    • Stroke Therapy Academic Industry Roundtable II (STAIR-II). Recommendations for clinical trial evaluation of acute stroke therapies. Stroke. 2001;32:1598-606.
    • (2001) Stroke , vol.32 , pp. 1598-1606
  • 108
    • 67349222548 scopus 로고    scopus 로고
    • Sensorimotor behavioral effects of endothelin-1 induced small cortical infarcts in C57BL/6 mice
    • Tennant KA, Jones TA. Sensorimotor behavioral effects of endothelin-1 induced small cortical infarcts in C57BL/6 mice. J Neurosci Methods. 2009;181:18-26.
    • (2009) J Neurosci Methods , vol.181 , pp. 18-26
    • Tennant, K.A.1    Jones, T.A.2
  • 109
    • 0028783948 scopus 로고
    • Tissue plasminogen activator for acute ischemic stroke
    • The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581-7.
    • (1995) N Engl J Med , vol.333 , pp. 1581-1587
  • 110
    • 33644849222 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2006 update. A report from the American heart association statistics committee and stroke statistics subcommittee
    • Thom T, Haase N, Rosamond W, Howard VJ, Rumsfeld J, Manolio T, et al. Heart disease and stroke statistics-2006 update. A report from the American heart association statistics committee and stroke statistics subcommittee. Circulation. 2006;113:e85-151.
    • (2006) Circulation , vol.113 , pp. e85-151
    • Thom, T.1    Haase, N.2    Rosamond, W.3    Howard, V.J.4    Rumsfeld, J.5    Manolio, T.6
  • 112
    • 0032564240 scopus 로고    scopus 로고
    • Diagnosis as a guide to stroke therapy
    • Vuadens P, Bogousslavsky J. Diagnosis as a guide to stroke therapy. Lancet. 1998;352 Suppl 3:SIII5-9.
    • (1998) Lancet , vol.352 , pp. SIII5-SIII9
    • Vuadens, P.1    Bogousslavsky, J.2
  • 113
    • 0035975027 scopus 로고    scopus 로고
    • An improved version of embolic model of brain ischemic injury in the rat
    • Wang CX, Yang T, Shuaib A. An improved version of embolic model of brain ischemic injury in the rat. J Neurosci Methods. 2001;109:147-51.
    • (2001) J Neurosci Methods , vol.109 , pp. 147-151
    • Wang, C.X.1    Yang, T.2    Shuaib, A.3
  • 114
    • 3042739740 scopus 로고    scopus 로고
    • 3',4'-Dihydroxyflavonol reduces infarct size and injury associated with myocardial ischaemia and reperfusion in sheep
    • Wang S, Dusting GJ, May CN, Woodman OL. 3',4'-Dihydroxyflavonol reduces infarct size and injury associated with myocardial ischaemia and reperfusion in sheep. Br J Pharmacol. 2004;142:443-52.
    • (2004) Br J Pharmacol , vol.142 , pp. 443-452
    • Wang, S.1    Dusting, G.J.2    May, C.N.3    Woodman, O.L.4
  • 116
    • 34548127060 scopus 로고    scopus 로고
    • Neurogenesis associated with endothelin-induced cortical infarction in the mouse
    • Wang Y, Jin K, Greenberg DA. Neurogenesis associated with endothelin-induced cortical infarction in the mouse. Brain Res. 2007;1167:118-22.
    • (2007) Brain Res , vol.1167 , pp. 118-122
    • Wang, Y.1    Jin, K.2    Greenberg, D.A.3
  • 117
    • 0021826450 scopus 로고
    • Induction of reproducible brain infarction by photochemically initiated thrombosis
    • Watson BD, Dietrich WD, Busto R, Wachtel MS, Ginsberg MD. Induction of reproducible brain infarction by photochemically initiated thrombosis. Ann Neurol. 1985;17:497-504.
    • (1985) Ann Neurol , vol.17 , pp. 497-504
    • Watson, B.D.1    Dietrich, W.D.2    Busto, R.3    Wachtel, M.S.4    Ginsberg, M.D.5
  • 118
    • 33751006424 scopus 로고    scopus 로고
    • AM-36 modulates the neutrophil inflammatory response and reduces breakdown of the blood brain barrier after endothelin-1 induced focal brain ischaemia
    • Weston RM, Jarrott B, Ishizuka Y, Callaway JK. AM-36 modulates the neutrophil inflammatory response and reduces breakdown of the blood brain barrier after endothelin-1 induced focal brain ischaemia. Br J Pharmacol. 2006;149:712-23.
    • (2006) Br J Pharmacol , vol.149 , pp. 712-723
    • Weston, R.M.1    Jarrott, B.2    Ishizuka, Y.3    Callaway, J.K.4
  • 119
    • 11144353392 scopus 로고    scopus 로고
    • Endothelin receptor pharmacology and function in the mouse: Comparison with rat and man
    • Wiley KE, Davenport AP. Endothelin receptor pharmacology and function in the mouse: comparison with rat and man. J Cardiovasc Pharmacol. 2004;44 Suppl 1:S4-6.
    • (2004) J Cardiovasc Pharmacol , vol.44 , pp. S4-S6
    • Wiley, K.E.1    Davenport, A.P.2
  • 121
    • 18144417848 scopus 로고    scopus 로고
    • Fluoxetine and recovery of motor function after focal ischemia in rats
    • Windle V, Corbett D. Fluoxetine and recovery of motor function after focal ischemia in rats. Brain Res. 2005;1044:25-32.
    • (2005) Brain Res , vol.1044 , pp. 25-32
    • Windle, V.1    Corbett, D.2
  • 122
    • 33644554212 scopus 로고    scopus 로고
    • Comparison of different intravascular thread occlusion models for experimental stroke in rats
    • Woitzik J, Schneider UC, Thome C, Schroeck H, Schilling L. Comparison of different intravascular thread occlusion models for experimental stroke in rats. J Neurosci Methods. 2006;151:224-31.
    • (2006) J Neurosci Methods , vol.151 , pp. 224-231
    • Woitzik, J.1    Schneider, U.C.2    Thome, C.3    Schroeck, H.4    Schilling, L.5
  • 124
    • 0036267791 scopus 로고    scopus 로고
    • Anesthetic methods in rats determine outcome after experimental focal cerebral ischemia: Mechanical ventilation is required to obtain controlled experimental conditions
    • Zausinger S, Baethmann A, Schmid-Elsaesser R. Anesthetic methods in rats determine outcome after experimental focal cerebral ischemia: mechanical ventilation is required to obtain controlled experimental conditions. Brain Res Brain Res Protoc. 2002;9:112-21.
    • (2002) Brain Res Brain Res Protoc , vol.9 , pp. 112-121
    • Zausinger, S.1    Baethmann, A.2    Schmid-Elsaesser, R.3
  • 127
    • 16844372455 scopus 로고    scopus 로고
    • Functional recovery in aged and young rats after embolic stroke: Treatment with a phosphodiesterase type 5 inhibitor
    • Zhang L, Zhang RL, Wang Y, Zhang C, Zhang ZG, Meng H, Chopp M. Functional recovery in aged and young rats after embolic stroke: treatment with a phosphodiesterase type 5 inhibitor. Stroke. 2005;36:847-52.
    • (2005) Stroke , vol.36 , pp. 847-852
    • Zhang, L.1    Zhang, R.L.2    Wang, Y.3    Zhang, C.4    Zhang, Z.G.5    Meng, H.6    Chopp, M.7
  • 128
    • 39149120805 scopus 로고    scopus 로고
    • Suppressive effects of flavonoid fisetin on lipopolysaccharide-induced microglial activation and neurotoxicity
    • Zheng LT, Ock J, Kwon BM, Suk K. Suppressive effects of flavonoid fisetin on lipopolysaccharide-induced microglial activation and neurotoxicity. Int Immunopharmacol. 2008;8:484-94.
    • (2008) Int Immunopharmacol , vol.8 , pp. 484-494
    • Zheng, L.T.1    Ock, J.2    Kwon, B.M.3    Suk, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.