AM-36 modulates the neutrophil inflammatory response and reduces breakdown of the blood brain barrier after endothelin-1 induced focal brain ischaemia

British Journal of Pharmacology

Volumn 149, Issue 6, 2006, Pages 712-723

  Weston, R M ^a,b   Jarrott, B ^b   Ishizuka, Y ^a,c   Callaway, J K ^b  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

AM 36; Blood brain barrier; Cerebral ischaemia; Endothelin; Macrophages; Neutrophils

Indexed keywords

1 [2 (4 CHLOROPHENYL) 2 HYDROXY]ETHYL 4 [3,5 BIS(1,1 DIMETHYLETHYL) 4 HYDROXYPHENYL]METHYLPIPERAZINE; AM 36; ANTIOXIDANT; ENDOTHELIN 1; MYELOPEROXIDASE; PIPERAZINE DERIVATIVE; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN REGION; CELL LABELING; CONTROLLED STUDY; CONVALESCENCE; ENZYME ASSAY; IMAGE ANALYSIS; IMMUNOFLUORESCENCE TEST; INFLAMMATORY INFILTRATE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROMODULATION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT; STROKE; TASK PERFORMANCE; THERAPY EFFECT; TISSUE SECTION; TREATMENT RESPONSE;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN ISCHEMIA; ENDOTHELIN-1; FLUORESCENT ANTIBODY TECHNIQUE; INFLAMMATION; MALE; MICROSCOPY, CONFOCAL; NEUTROPHILS; PEROXIDASE; PIPERAZINES; RATS; RATS, LONG-EVANS;

EID: 33751006424     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706918     Document Type: Article

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