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Volumn 57, Issue 2, 1999, Pages 199-208

Influence of the antioxidant quercetin in vivo on the level of nitric oxide determined by electron paramagnetic resonance in rat brain during global ischemia and reperfusion

Author keywords

Antioxidants; Electron paramagnetic resonance; Flavonoids; Global brain ischemia and reperfusion; Nitric oxide measurement; Superoxide scavenging

Indexed keywords

ANTIOXIDANT; FLAVONOID; NITRIC OXIDE; QUERCETIN; SCAVENGER; SUPEROXIDE; SUPEROXIDE DISMUTASE MACROGOL;

EID: 0032901807     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00296-2     Document Type: Article
Times cited : (167)

References (66)
  • 2
    • 0027496238 scopus 로고
    • A radical hypothesis for neurodegeneration
    • Olanow C.W. A radical hypothesis for neurodegeneration. Trends Neurosci. 16:1993;439-444.
    • (1993) Trends Neurosci , vol.16 , pp. 439-444
    • Olanow, C.W.1
  • 3
    • 0028173654 scopus 로고
    • A "radical" view of cerebral ischemic injury
    • Phillis J.W. A "radical" view of cerebral ischemic injury. Prog Neurobiol. 42:1994;441-448.
    • (1994) Prog Neurobiol , vol.42 , pp. 441-448
    • Phillis, J.W.1
  • 4
    • 0030203367 scopus 로고    scopus 로고
    • The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury
    • Szabo C. The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury. Shock. 6:1996;79-88.
    • (1996) Shock , vol.6 , pp. 79-88
    • Szabo, C.1
  • 5
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate and neurodegenerative disorders
    • Coyle J.T., Puttfarcken P. Oxidative stress, glutamate and neurodegenerative disorders. Science. 262:1993;689-695.
    • (1993) Science , vol.262 , pp. 689-695
    • Coyle, J.T.1    Puttfarcken, P.2
  • 6
    • 0027252546 scopus 로고
    • Contributory mechanisms in the causation of neurodegenerative disorders
    • Lees G.J. Contributory mechanisms in the causation of neurodegenerative disorders. Neuroscience. 54:1993;287-322.
    • (1993) Neuroscience , vol.54 , pp. 287-322
    • Lees, G.J.1
  • 7
    • 0026712171 scopus 로고
    • Lipid peroxidation - A common pathogenetic mechanism?
    • Dargel R. Lipid peroxidation - a common pathogenetic mechanism? Exp Toxicol Pathol. 44:1992;1169-1181.
    • (1992) Exp Toxicol Pathol , vol.44 , pp. 1169-1181
    • Dargel, R.1
  • 8
    • 0029144638 scopus 로고
    • Nitric oxide and oxygen radicals: A question of balance
    • Darley-Usmar V., Wiseman H., Halliwell B. Nitric oxide and oxygen radicals A question of balance . FEBS Lett. 369:1995;131-135.
    • (1995) FEBS Lett , vol.369 , pp. 131-135
    • Darley-Usmar, V.1    Wiseman, H.2    Halliwell, B.3
  • 9
    • 0028132836 scopus 로고
    • Redox signalling: Nitrosylation and related target interactions of nitric oxide
    • Stamler J.S. Redox signalling Nitrosylation and related target interactions of nitric oxide . Cell. 78:1994;931-936.
    • (1994) Cell , vol.78 , pp. 931-936
    • Stamler, J.S.1
  • 10
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • Beckman J.S., Beckman T.W., Chen J., Marshall P.A., Freeman B.A. Apparent hydroxyl radical production by peroxynitrite Implications for endothelial injury from nitric oxide and superoxide . Proc Natl Acad Sci USA. 87:1990;1620-1624.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 11
    • 0028641246 scopus 로고
    • Peroxynitrite versus hydroxyl radical: The role of nitric oxide in superoxide-dependent cerebral injury
    • Beckman J.S. Peroxynitrite versus hydroxyl radical The role of nitric oxide in superoxide-dependent cerebral injury . Ann NY Acad Sci. 738:1994;69-75.
    • (1994) Ann NY Acad Sci , vol.738 , pp. 69-75
    • Beckman, J.S.1
  • 12
    • 0030628410 scopus 로고    scopus 로고
    • Henricks, Sadeghi-Hashjin G and Nijkamp FP. Peroxynitrite: A two-faced metabolite of nitric oxide
    • Muijsers R.B.R., Folkerts G. Henricks, Sadeghi-Hashjin G and Nijkamp FP. Peroxynitrite A two-faced metabolite of nitric oxide . Life Sci. 60:1997;1833-1845.
    • (1997) Life Sci , vol.60 , pp. 1833-1845
    • Muijsers, R.B.R.1    Folkerts, G.2
  • 13
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide and peroxynitrite: The good, the bad, and the ugly
    • Beckman J.S., Koppenol W.H. Nitric oxide, superoxide and peroxynitrite The good, the bad, and the ugly . Am J Physiol. 271:1996;C1424-C1437.
    • (1996) Am J Physiol , vol.271
    • Beckman, J.S.1    Koppenol, W.H.2
  • 14
    • 0025874048 scopus 로고
    • Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide
    • Radi R., Beckman J.S., Bush K.M., Freeman B.A. Peroxynitrite-induced membrane lipid peroxidation The cytotoxic potential of superoxide and nitric oxide . Arch Biochem Biophys. 288:1991;481-489.
    • (1991) Arch Biochem Biophys , vol.288 , pp. 481-489
    • Radi, R.1    Beckman, J.S.2    Bush, K.M.3    Freeman, B.A.4
  • 15
    • 0027974136 scopus 로고
    • One- And two-electron oxidations of methionine by peroxynitrite
    • Pryor W.A., Jim X., Squadrito G.L. One- and two-electron oxidations of methionine by peroxynitrite. Proc Natl Acad Sci USA. 91:1994;11173-11177.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11173-11177
    • Pryor, W.A.1    Jim, X.2    Squadrito, G.L.3
  • 16
    • 0025730414 scopus 로고
    • Peroxynitrite oxidation of sulfhydrils. The cytotoxic potential of superoxide and nitric oxide
    • Radi R., Beckman J.S., Bush K.M., Freeman B.A. Peroxynitrite oxidation of sulfhydrils. The cytotoxic potential of superoxide and nitric oxide. J Biol Chem. 266:1991;4244-4250.
    • (1991) J Biol Chem , vol.266 , pp. 4244-4250
    • Radi, R.1    Beckman, J.S.2    Bush, K.M.3    Freeman, B.A.4
  • 17
    • 9444245614 scopus 로고
    • The nitration and hydroxylation of aromatic compounds by peroxynitrous acid
    • Halfpenny E., Robinson P.L. The nitration and hydroxylation of aromatic compounds by peroxynitrous acid. J Chem Soc (A). 1952;939-946.
    • (1952) J Chem Soc (A) , pp. 939-946
    • Halfpenny, E.1    Robinson, P.L.2
  • 19
    • 0024571782 scopus 로고
    • Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury
    • Liu T.H., Beckman J.S., Freeman B.A., Hogan E.L., Hsu S.Y. Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury. Am J Physiol. 256:1989;H589-H593.
    • (1989) Am J Physiol , vol.256
    • Liu, T.H.1    Beckman, J.S.2    Freeman, B.A.3    Hogan, E.L.4    Hsu, S.Y.5
  • 21
    • 0026345023 scopus 로고
    • Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn-superoxide dismutase
    • Kinouchi H., Epstein C.J., Mizui T., Carlson E., Chen S.F., Chan P.H. Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn-superoxide dismutase. Proc Natl Acad Sci USA. 88:1991;11158-11162.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 11158-11162
    • Kinouchi, H.1    Epstein, C.J.2    Mizui, T.3    Carlson, E.4    Chen, S.F.5    Chan, P.H.6
  • 22
    • 0025237287 scopus 로고
    • Protective effect of α-tocopherol on ischemic neuronal damage in the gerbil hippocampus
    • Hara H., Kato H., Kogure K. Protective effect of α-tocopherol on ischemic neuronal damage in the gerbil hippocampus. Brain Res. 510:1990;335-338.
    • (1990) Brain Res , vol.510 , pp. 335-338
    • Hara, H.1    Kato, H.2    Kogure, K.3
  • 23
    • 0025088070 scopus 로고
    • Protection from cerebral ischemic injury in gerbils with the spin trap agent N-tert-butyl-α-phenylnitrone (PBN)
    • Phillis J.W., Clough-Helfman C. Protection from cerebral ischemic injury in gerbils with the spin trap agent N-tert-butyl-α-phenylnitrone (PBN). Neurosci Lett. 116:1990;315-319.
    • (1990) Neurosci Lett , vol.116 , pp. 315-319
    • Phillis, J.W.1    Clough-Helfman, C.2
  • 24
    • 0026512905 scopus 로고
    • Deoxycoformycin and oxypurinol: Protection against focal ischemic brain injury in the rat
    • Lin Y., Phillis J.W. Deoxycoformycin and oxypurinol Protection against focal ischemic brain injury in the rat . Brain Res. 571:1992;272-280.
    • (1992) Brain Res , vol.571 , pp. 272-280
    • Lin, Y.1    Phillis, J.W.2
  • 26
    • 0029029094 scopus 로고
    • A synthetic flavonoid promotes EDRF-induced relaxation of rabbit arteries in vitro: Evidence for superoxide scavenging
    • Girard P., Sercombe R., Sercombe C., Le Lem G., Seylaz J., Potier P. A synthetic flavonoid promotes EDRF-induced relaxation of rabbit arteries in vitro Evidence for superoxide scavenging . Biochem Pharmacol. 49:1995;1533-1539.
    • (1995) Biochem Pharmacol , vol.49 , pp. 1533-1539
    • Girard, P.1    Sercombe, R.2    Sercombe, C.3    Le Lem, G.4    Seylaz, J.5    Potier, P.6
  • 27
    • 0023864255 scopus 로고
    • Flavonoids are scavengers of superoxide anions
    • Robak J., Gryglewski R.J. Flavonoids are scavengers of superoxide anions. Biochem Pharmacol. 37:1988;837-841.
    • (1988) Biochem Pharmacol , vol.37 , pp. 837-841
    • Robak, J.1    Gryglewski, R.J.2
  • 28
    • 0009538299 scopus 로고
    • Hydroxyl radical scavenging activity of flavonoids
    • Rafat Husain S., Cillard J., Cillard P. Hydroxyl radical scavenging activity of flavonoids. Phytochemistry. 26:1987;2489-2491.
    • (1987) Phytochemistry , vol.26 , pp. 2489-2491
    • Rafat Husain, S.1    Cillard, J.2    Cillard, P.3
  • 29
    • 0025050374 scopus 로고
    • Flavonoids as superoxide scavengers and antioxidants
    • Chen Y., Zheng R., Jia Z., Ju Y. Flavonoids as superoxide scavengers and antioxidants. Free Radical Biol Med. 9:1990;19-21.
    • (1990) Free Radical Biol Med , vol.9 , pp. 19-21
    • Chen, Y.1    Zheng, R.2    Jia, Z.3    Ju, Y.4
  • 30
    • 0028318752 scopus 로고
    • The correlation between active oxygen scavenging and antioxidative effects of flavonoids
    • Hanasaki Y., Ogawa S., Fukui S. The correlation between active oxygen scavenging and antioxidative effects of flavonoids. Free Radical Biol Med. 16:1994;845-850.
    • (1994) Free Radical Biol Med , vol.16 , pp. 845-850
    • Hanasaki, Y.1    Ogawa, S.2    Fukui, S.3
  • 31
    • 0021947045 scopus 로고
    • Inhibitory action of quercetin on xanthine oxidase and xanthine dehydrogenase activity
    • Bindoli A., Valente M., Cavallini L. Inhibitory action of quercetin on xanthine oxidase and xanthine dehydrogenase activity. Pharmacol Res Comms. 17:1985;831-839.
    • (1985) Pharmacol Res Comms , vol.17 , pp. 831-839
    • Bindoli, A.1    Valente, M.2    Cavallini, L.3
  • 32
    • 0018347695 scopus 로고
    • A new model of bilateral hemispheric ischemia in the unanesthetized rat
    • Pulsinelli W.A., Brierley J.B. A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke. 10:1979;267-272.
    • (1979) Stroke , vol.10 , pp. 267-272
    • Pulsinelli, W.A.1    Brierley, J.B.2
  • 33
    • 0028238555 scopus 로고
    • Electron paramagnetic resonance study on nitric oxide production during brain focal ischemia and reperfusion in the rat
    • Sato S., Tominaga T., Ohnishi T., Ohnishi S.T. Electron paramagnetic resonance study on nitric oxide production during brain focal ischemia and reperfusion in the rat. Brain Res. 647:1994;91-96.
    • (1994) Brain Res , vol.647 , pp. 91-96
    • Sato, S.1    Tominaga, T.2    Ohnishi, T.3    Ohnishi, S.T.4
  • 35
    • 85007884503 scopus 로고
    • Effects of isorhamnetin, rhamnetin, and quercetin on the concentrations of cholesterol and lipoperoxide in the serum and liver and on the blood and liver antioxidative enzyme activities of rats
    • Igarashi K., Ohmuma M. Effects of isorhamnetin, rhamnetin, and quercetin on the concentrations of cholesterol and lipoperoxide in the serum and liver and on the blood and liver antioxidative enzyme activities of rats. Biosci Biotech Biochem. 59:1995;595-601.
    • (1995) Biosci Biotech Biochem , vol.59 , pp. 595-601
    • Igarashi, K.1    Ohmuma, M.2
  • 36
    • 0026579380 scopus 로고
    • EPR evidence for nitric oxide production from guanidino nitrogens of L-arginine in animal tissues in vivo
    • Kubrina I.N., Caldwell W.S., Mordvintcev P.I., Malenkova I.V., Vanin A.F. EPR evidence for nitric oxide production from guanidino nitrogens of L-arginine in animal tissues in vivo. Biochim Biophys Acta. 1099:1992;233-237.
    • (1992) Biochim Biophys Acta , vol.1099 , pp. 233-237
    • Kubrina, I.N.1    Caldwell, W.S.2    Mordvintcev, P.I.3    Malenkova, I.V.4    Vanin, A.F.5
  • 37
    • 0027152090 scopus 로고
    • EPR spin-trapping study of nitric oxide formation during bilateral carotid occlusion in the rat
    • Sato S., Tominaga T., Ohnishi T., Ohnishi S.T. EPR spin-trapping study of nitric oxide formation during bilateral carotid occlusion in the rat. Biochim Biophys Acta. 1181:1993;195-197.
    • (1993) Biochim Biophys Acta , vol.1181 , pp. 195-197
    • Sato, S.1    Tominaga, T.2    Ohnishi, T.3    Ohnishi, S.T.4
  • 38
    • 0027287924 scopus 로고
    • Potentiation of nitric oxide formation following bilateral carotid occlusion and focal cerebral ischemia in the rat: In vivo detection of nitric oxide radical by electron paramagnetic resonance spin trapping
    • Tominaga T., Sato S., Ohnishi T., Ohnishi S.T. Potentiation of nitric oxide formation following bilateral carotid occlusion and focal cerebral ischemia in the rat In vivo detection of nitric oxide radical by electron paramagnetic resonance spin trapping . Brain Res. 614:1993;342-346.
    • (1993) Brain Res , vol.614 , pp. 342-346
    • Tominaga, T.1    Sato, S.2    Ohnishi, T.3    Ohnishi, S.T.4
  • 39
    • 0028025095 scopus 로고
    • Electron paramagnetic resonance (EPR) detection of nitric oxide produced during forebrain ischemia of the rat
    • Tominaga T., Sato S., Ohnishi T., Ohnishi S.T. Electron paramagnetic resonance (EPR) detection of nitric oxide produced during forebrain ischemia of the rat. J Cereb Blood Flow Metabol. 14:1994;715-722.
    • (1994) J Cereb Blood Flow Metabol , vol.14 , pp. 715-722
    • Tominaga, T.1    Sato, S.2    Ohnishi, T.3    Ohnishi, S.T.4
  • 43
    • 0027323351 scopus 로고
    • Inhibition of rat cerebellar nitric oxide synthase by 7-nitro indazole and related substituted indazoles
    • Babbedge R.C., Bland-Ward P.A., Hart S.L., Moore P.K. Inhibition of rat cerebellar nitric oxide synthase by 7-nitro indazole and related substituted indazoles. Br J Pharmacol. 110:1993;225-228.
    • (1993) Br J Pharmacol , vol.110 , pp. 225-228
    • Babbedge, R.C.1    Bland-Ward, P.A.2    Hart, S.L.3    Moore, P.K.4
  • 44
    • 0028000460 scopus 로고
    • Bland-Ward PA, Moore PK, Jenner P and Marsden CD, Time-course of inhibition of brain nitric oxide synthase by 7-nitro indazole
    • MacKenzie G.M., Rose S. Bland-Ward PA, Moore PK, Jenner P and Marsden CD, Time-course of inhibition of brain nitric oxide synthase by 7-nitro indazole. Neuroreport. 5:1994;1993-1996.
    • (1994) Neuroreport , vol.5 , pp. 1993-1996
    • MacKenzie, G.M.1    Rose, S.2
  • 45
    • 0028092958 scopus 로고
    • Nitric oxide synthases: Roles, tolls and controls
    • Nathan C., Xie Q-w. Nitric oxide synthases Roles, tolls and controls . Cell. 78:1994;915-918.
    • (1994) Cell , vol.78 , pp. 915-918
    • Nathan, C.1    Xie, Q.-W.2
  • 46
    • 0028998421 scopus 로고
    • S-nitrosothiols and the bioregulatory actions of nitrogen oxides through reactions with thiol groups
    • Stamler J.S. S-nitrosothiols and the bioregulatory actions of nitrogen oxides through reactions with thiol groups. Curr Top Microbiol Immunol. 196:1995;19-36.
    • (1995) Curr Top Microbiol Immunol , vol.196 , pp. 19-36
    • Stamler, J.S.1
  • 47
    • 0027523390 scopus 로고
    • NO, thiols and disulfides
    • Girard P., Potier P. NO, thiols and disulfides. FEBS Lett. 320:1993;7-8.
    • (1993) FEBS Lett , vol.320 , pp. 7-8
    • Girard, P.1    Potier, P.2
  • 48
    • 0028824722 scopus 로고
    • Thiol dependence of nitric oxide synthase
    • Hofmann H., Schmidt H.H.H.W. Thiol dependence of nitric oxide synthase. Biochemistry. 34:1995;13443-13452.
    • (1995) Biochemistry , vol.34 , pp. 13443-13452
    • Hofmann, H.1    Schmidt, H.H.H.W.2
  • 49
    • 0029927487 scopus 로고    scopus 로고
    • The role of gluthatione in the transport and catabolism of nitric oxide
    • Hogg N., Singh R.J., Kalyanaraman B. The role of gluthatione in the transport and catabolism of nitric oxide. FEBS Lett. 382:1996;223-228.
    • (1996) FEBS Lett , vol.382 , pp. 223-228
    • Hogg, N.1    Singh, R.J.2    Kalyanaraman, B.3
  • 50
    • 0031938717 scopus 로고    scopus 로고
    • Role of glutathione in nitric oxide-dependent regulation of energy metabolism in rat hepatoma cells
    • Nishikawa M., Sato E.F., Kashiba M., Kuroki T., Utsumi K., Inoue M. Role of glutathione in nitric oxide-dependent regulation of energy metabolism in rat hepatoma cells. Hepatology. 27:1998;422-426.
    • (1998) Hepatology , vol.27 , pp. 422-426
    • Nishikawa, M.1    Sato, E.F.2    Kashiba, M.3    Kuroki, T.4    Utsumi, K.5    Inoue, M.6
  • 51
    • 0028935932 scopus 로고
    • Effect of food deprivation on glutathione and amino acid levels in brain and liver of young and aged rats
    • Benuck M., Banay-Schwartz M., DeGuzman T., Lajtha A. Effect of food deprivation on glutathione and amino acid levels in brain and liver of young and aged rats. Brain Res. 678:1995;259-264.
    • (1995) Brain Res , vol.678 , pp. 259-264
    • Benuck, M.1    Banay-Schwartz, M.2    Deguzman, T.3    Lajtha, A.4
  • 52
  • 54
    • 0028240615 scopus 로고
    • Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia
    • Endoh M., Maiese K., Wagner J. Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia. Brain Res. 651:1994;92-100.
    • (1994) Brain Res , vol.651 , pp. 92-100
    • Endoh, M.1    Maiese, K.2    Wagner, J.3
  • 56
    • 0020067965 scopus 로고
    • Temporal profile of neuronal damage in a model of transient forebrain ischemia
    • Pulsinelli W.A., Brierley J.B., Plum F. Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann Neurol. 11:1982;491-498.
    • (1982) Ann Neurol , vol.11 , pp. 491-498
    • Pulsinelli, W.A.1    Brierley, J.B.2    Plum, F.3
  • 57
    • 0021236076 scopus 로고
    • Cerebral circulation and metabolism
    • Siesjo B.K. Cerebral circulation and metabolism. J Neurosurg. 60:1984;883-908.
    • (1984) J Neurosurg , vol.60 , pp. 883-908
    • Siesjo, B.K.1
  • 58
    • 0021225723 scopus 로고
    • The density and distribution of ischemic brain injury in the rat following 2-10 min of forebrain ischemia
    • Smith M.-L., Auer R.N., Siesjo B.K. The density and distribution of ischemic brain injury in the rat following 2-10 min of forebrain ischemia. Acta Neuropathol. 64:1984;319-332.
    • (1984) Acta Neuropathol , vol.64 , pp. 319-332
    • Smith, M.-L.1    Auer, R.N.2    Siesjo, B.K.3
  • 59
    • 0020069661 scopus 로고
    • Regional cerebral blood flow and glucose metabolism following transient forebrain ischemia
    • Pulsinelli W.A., Levy D.E., Duffy T.E. Regional cerebral blood flow and glucose metabolism following transient forebrain ischemia. Ann Neurol. 11:1982;499-509.
    • (1982) Ann Neurol , vol.11 , pp. 499-509
    • Pulsinelli, W.A.1    Levy, D.E.2    Duffy, T.E.3
  • 60
    • 0029917236 scopus 로고    scopus 로고
    • Ketamine antagonizes nitric oxide release from cerebral cortex after middle cerebral artery ligation in rats
    • Lin S.-Z., Chiou A.-L., Wang Y. Ketamine antagonizes nitric oxide release from cerebral cortex after middle cerebral artery ligation in rats. Stroke. 27:1996;747-752.
    • (1996) Stroke , vol.27 , pp. 747-752
    • Lin, S.-Z.1    Chiou, A.-L.2    Wang, Y.3
  • 61
    • 0030893203 scopus 로고    scopus 로고
    • Early nitric oxide increase in depolarized tissue of cat focal cerebral ischemia
    • Ohta K., Graf R., Rosner G., Kumura E., Heiss W.-D. Early nitric oxide increase in depolarized tissue of cat focal cerebral ischemia. Neuroreport. 8:1996;143-148.
    • (1996) Neuroreport , vol.8 , pp. 143-148
    • Ohta, K.1    Graf, R.2    Rosner, G.3    Kumura, E.4    Heiss, W.-D.5
  • 62
    • 0027245908 scopus 로고
    • Nitric oxide measured by a porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion
    • Malinski T., Bailey F., Zhang Z.G., Chopp M. Nitric oxide measured by a porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab. 13:1993;355-358.
    • (1993) J Cereb Blood Flow Metab , vol.13 , pp. 355-358
    • Malinski, T.1    Bailey, F.2    Zhang, Z.G.3    Chopp, M.4
  • 66
    • 0030972992 scopus 로고    scopus 로고
    • Postischemic, systemic administration of polyamine-modified superoxide dismutase reduces hippocampal CA1 neurodegeneration in rat global cerebral ischemia
    • Wengenack T.M., Curran G.L., Podluso J.F. Postischemic, systemic administration of polyamine-modified superoxide dismutase reduces hippocampal CA1 neurodegeneration in rat global cerebral ischemia. Brain Res. 754:1997;46-54.
    • (1997) Brain Res , vol.754 , pp. 46-54
    • Wengenack, T.M.1    Curran, G.L.2    Podluso, J.F.3


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