The endolysosomal cysteine cathepsins L and K are involved in macrophage-mediated clearance of Staphylococcus aureus and the concomitant cytokine induction

FASEB Journal

Volumn 28, Issue 1, 2014, Pages 162-175

  Müller, Sabrina ^a,b   Faulhaber, Anja ^a   Sieber, Carolin ^a   Pfeifer, Dietmar ^b   Hochberg, Tanja ^a   Gansz, Martina ^a   Deshmukh, Sachin D ^b   Dauth, Stephanie ^c   Brix, Klaudia ^c   Saftig, Paul ^d   Peters, Christoph ^a   Henneke, Philipp ^b   Reinheckel, Thomas ^a,b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c JACOBS UNIVERSITY BREMEN   (Germany)

^d UNIVERSITY OF KIEL   (Germany)

Author keywords

Innate immune system; Lysosome; Nonoxidative killing; Phagocyte; Proteases

Indexed keywords

CATHEPSIN K; CATHEPSIN L; CYTOKINE; INTERLEUKIN 6; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9;

ANIMAL CELL; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL GROWTH; BACTERIAL SURVIVAL; BACTERICIDAL ACTIVITY; BONE MARROW; CELL SURFACE; CONTROLLED STUDY; CYTOKINE INDUCTION; FLUORESCENCE ACTIVATED CELL SORTING; GENE ONTOLOGY; IMMUNE RESPONSE; LYSOSOME; MACROPHAGE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN INDUCTION; RESPIRATORY BURST; STAPHYLOCOCCUS AUREUS; ANIMAL; CELL CULTURE; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; NONOXIDATIVE KILLING; PHAGOCYTE; PHYSIOLOGY; PROTEASES;

INNATE IMMUNE SYSTEM; LYSOSOME; NONOXIDATIVE KILLING; PHAGOCYTE; PROTEASES;

ANIMALS; CATHEPSIN K; CATHEPSIN L; CELLS, CULTURED; CYTOKINES; MACROPHAGES; MICE; PHAGOCYTOSIS; STAPHYLOCOCCUS AUREUS;

EID: 84894560482     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-232272     Document Type: Article

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