Olfactomedin 4 inhibits cathepsin C-mediated protease activities, thereby modulating neutrophil killing of Staphylococcus aureus and Escherichia coli in mice

Journal of Immunology

Volumn 189, Issue 5, 2012, Pages 2460-2467

  Liu, Wenli ^a   Yan, Ming ^b   Liu, Yueqin ^c   McLeish, Kenneth R ^d   Coleman, William G ^b   Rodgers, Griffin P ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN G; DIPEPTIDYL PEPTIDASE I; GLYCOPROTEIN; LEUKOCYTE ELASTASE; MYELOBLASTIN; OLFACTOMEDIN 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CLEARANCE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTION; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; LEUKOCYTE ACTIVATION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; WILD TYPE;

EID: 84865423217     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1103179     Document Type: Article

References (29)

1. Segal, A.W. 2005. How neutrophils kill microbes. Annu. Rev. Immunol. 23: 197-223.
2. Standish, A. J., and J. N. Weiser. 2009. Human neutrophils kill Streptococcus pneumoniae via serine proteases. J. Immunol. 183: 2602-2609.
3. Dolenc, I., B. Turk, G. Pungercic, A. Ritonja, and V. Turk. 1995. Oligomeric structure and substrate induced inhibition of human cathepsin C. J. Biol. Chem. 270: 21626-21631.
4. Pham, C. T. 2006. Neutrophil serine proteases: specific regulators of inflammation. Nat. Rev. Immunol. 6: 541-550.
5. Tomarev, S. I., and N. Nakaya. 2009. Olfactomedin domain-containing proteins: possible mechanisms of action and functions in normal development and pathology. Mol. Neurobiol. 40: 122-138.
6. Zhang, J., W. L. Liu, D. C. Tang, L. Chen, M. Wang, S. D. Pack, Z. Zhuang, and G. P. Rodgers. 2002. Identification and characterization of a novel member of olfactomedin-related protein family, hGC-1, expressed during myeloid lineage development. Gene 283: 83-93.
7. Zhang, X., Q. Huang, Z. Yang, Y. Li, and C. Y. Li. 2004. GW112, a novel antiapoptotic protein that promotes tumor growth. Cancer Res. 64: 2474-2481.
8. Liu, W., H. W. Lee, Y. Liu, R. Wang, and G. P. Rodgers. 2010. Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2′- deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis. Blood 116: 4938-4947.
9. Chen, L., H. Li, W. Liu, J. Zhu, X. Zhao, E. Wright, L. Cao, I. Ding, and G. P. Rodgers. 2011. Olfactomedin 4 suppresses prostate cancer cell growth and metastasis via negative interaction with cathepsin D and SDF-1. Carcinogenesis 32: 986-994.
10. Shinozaki, S., T. Nakamura, M. Iimura, Y. Kato, B. Iizuka, M. Kobayashi, and N. Hayashi. 2001. Upregulation of Reg 1alpha and GW112 in the epithelium of inflamed colonic mucosa. Gut 48: 623-629.
11. Mannick, E. E., J. R. Schurr, A. Zapata, J. J. Lentz, M. Gastanaduy, R. L. Cote, A. Delgado, P. Correa, and H. Correa. 2004. Gene expression in gastric biopsies from patients infected with Helicobacter pylori. Scand. J. Gastroenterol. 39: 1192-1200.
12. Liu, W., M. Yan, Y. Liu, R. Wang, C. Li, C. Deng, A. Singh, W. G. Coleman, Jr., and G. P. Rodgers. 2010. Olfactomedin 4 down-regulates innate immunity against Helicobacter pylori infection. Proc. Natl. Acad. Sci. USA 107: 11056-11061.
13. Liu, W., L. Chen, J. Zhu, and G. P. Rodgers. 2006. The glycoprotein hGC-1 binds to cadherin and lectins. Exp. Cell Res. 312: 1785-1797.
14. Boxio, R., C. Bossenmeyer-Pourié, N. Steinckwich, C. Dournon, and O. Nüsse. 2004. Mouse bone marrow contains large numbers of functionally competent neutrophils. J. Leukoc. Biol. 75: 604-611.
15. Lominadze, G., D. W. Powell, G. C. Luerman, A. J. Link, R. A. Ward, and K. R. McLeish. 2005. Proteomic analysis of human neutrophil granules. Mol. Cell. Proteomics 4: 1503-1521.
16. Liu, W., J. Zhu, L. Cao, and G. P. Rodgers. 2007. Expression of hGC-1 is correlated with differentiation of gastric carcinoma. Histopathology 51: 157-165.
17. Malaviya, R., E. A. Ross, J. I. MacGregor, T. Ikeda, J. R. Little, B. A. Jakschik, and S. N. Abraham. 1994. Mast cell phagocytosis of FimH-expressing enterobacteria. J. Immunol. 152: 1907-1914.
18. Suzuki, K., H. Ota, S. Sasagawa, T. Sakatani, and T. Fujikura. 1983. Assay method for myeloperoxidase in human polymorphonuclear leukocytes. Anal. Biochem. 132: 345-352.
19. Bjerknes, R., and C. F. Bassøe. 1984. Phagocyte C3-mediated attachment and internalization: flow cytometric studies using a fluorescence quenching technique. Blut 49: 315-323.
20. Mallen-St Clair, J., C. T. Pham, S. A. Villalta, G. H. Caughey, and P. J. Wolters. 2004. Mast cell dipeptidyl peptidase I mediates survival from sepsis. J. Clin. Invest. 113: 628-634.
21. van Duijn, P. J., M. J. Dautzenberg, and E. A. Oostdijk. 2011. Recent trends in antibiotic resistance in European ICUs. Curr. Opin. Crit. Care 17: 658-665.
22. Borregaard, N., and J. B. Cowland. 1997. Granules of the human neutrophilic polymorphonuclear leukocyte. Blood 89: 3503-3521.
23. Kjeldsen, L., A. H. Johnsen, H. Sengeløv, and N. Borregaard. 1993. Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase. J. Biol. Chem. 268: 10425-10432.
24. Pham, C. T. 2008. Neutrophil serine proteases fine-tune the inflammatory response. Int. J. Biochem. Cell Biol. 40: 1317-1333.
25. Guay, D., C. Beaulieu, and M. D. Percival. 2010. Therapeutic utility and medicinal chemistry of cathepsin C inhibitors. Curr. Top. Med. Chem. 10: 708-716.
26. Dahl, S. W., T. Halkier, C. Lauritzen, I. Dolenc, J. Pedersen, V. Turk, and B. Turk. 2001. Human recombinant pro-dipeptidyl peptidase I (cathepsin C) can be activated by cathepsins L and S but not by autocatalytic processing. Biochemistry 40: 1671-1678.
27. Hamilton, G., J. D. Colbert, A. W. Schuettelkopf, and C. Watts. 2008. Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis. EMBO J. 27: 499-508.
28. Clarke, T. B., K. M. Davis, E. S. Lysenko, A. Y. Zhou, Y. Yu, and J. N. Weiser. 2010. Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity. Nat. Med. 16: 228-231.
29. Inomata, H., T. Haraguchi, and Y. Sasai. 2008. Robust stability of the embryonic axial pattern requires a secreted scaffold for chordin degradation. Cell 134: 854-865.